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Article ; Online: Viral simulations in dreams: The effect of the COVID-19 pandemic on threatening dream content in a Finnish sample of diary dreams.

Loukola, Ville / Tuominen, Jarno / Kirsilä, Santeri / Kyyhkynen, Annimaaria / Lahdenperä, Maron / Parkkali, Lilja / Ranta, Emilia / Malinen, Eveliina / Vanhanen, Sanni / Välimaa, Katariina / Olkoniemi, Henri / Revonsuo, Antti / Valli, Katja

Consciousness and cognition

2024 Volume 119, Page(s) 103651

Abstract: Previous research indicates that the COVID-19 pandemic has affected dreaming negatively. We compared 1132 dreams collected with prospective two-week dream diary during the pandemic to 166 dreams collected before the pandemic. We hypothesized that the ... ...

Abstract	Previous research indicates that the COVID-19 pandemic has affected dreaming negatively. We compared 1132 dreams collected with prospective two-week dream diary during the pandemic to 166 dreams collected before the pandemic. We hypothesized that the pandemic would increase the number of threatening events, threats related to diseases, and the severity of threats. We also hypothesized that dreams that include direct references to the pandemic will include more threatening events, more disease-related threats, and more severe threats. In contradiction with our hypotheses, results showed no differences between pandemic and pre-pandemic samples in the number of threats, threats related to diseases, or severe threats. However, dreams with direct references to the pandemic had more threats, disease-related threats, and severe threats. Our results thus do not suggest a significant overall increase in nightmarish or threatening dream content during the pandemic but show a more profound effect on a minority of dreams.
MeSH term(s)	Humans ; Dreams ; Pandemics ; Finland/epidemiology ; Prospective Studies ; COVID-19
Language	English
Publishing date	2024-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1106647-7
ISSN	1090-2376 ; 1053-8100
ISSN (online)	1090-2376
ISSN	1053-8100
DOI	10.1016/j.concog.2024.103651
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Article ; Online: Correlation between apparent diffusion coefficient value on diffusion-weighted MR imaging and Gleason score in prostate cancer.

Wu, X / Reinikainen, P / Vanhanen, A / Kapanen, M / Vierikko, T / Ryymin, P / Hyödynmaa, S / Kellokumpu-Lehtinen, P-L

Diagnostic and interventional imaging

2017 Volume 98, Issue 1, Page(s) 63–71

Abstract: Objectives: To investigate whether diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the diagnostic performance of ADC and normalized ADC (nADC: normalized to non- ... ...

Abstract	Objectives: To investigate whether diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the diagnostic performance of ADC and normalized ADC (nADC: normalized to non-tumor tissue). Patients and methods: Thirty pre-treatment patients (mean age, 69years; range: 59-78years) with prostate cancer underwent magnetic resonance imaging (MRI) examination, including DWI with three b values: 50, 400, and 800s/mm Results: The tumor minimum ADC (ADC Conclusion: Tumor ADC
Language	English
Publishing date	2017-01
Publishing country	France
Document type	Journal Article
ZDB-ID	2648283-6
ISSN	2211-5684 ; 2211-5684
ISSN (online)	2211-5684
ISSN	2211-5684
DOI	10.1016/j.diii.2016.08.009
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Article ; Online: Cerebrospinal fluid dynamics in idiopathic intracranial hypertension: a literature review and validation of contemporary findings.

Kaipainen, Aku L / Martoma, Erik / Puustinen, Tero / Tervonen, Joona / Jyrkkänen, Henna-Kaisa / Paterno, Jussi J / Kotkansalo, Anna / Rantala, Susanna / Vanhanen, Ulla / Leinonen, Ville / Lehto, Soili M / Iso-Mustajärvi, Matti / Elomaa, Antti-Pekka / Qvarlander, Sara / Huuskonen, Terhi J

Acta neurochirurgica

2021 Volume 163, Issue 12, Page(s) 3353–3368

Abstract: Background: Idiopathic intracranial hypertension (IIH) is a rare disease of unknown aetiology related possibly to disturbed cerebrospinal fluid (CSF) dynamics and characterised by elevated intracranial pressure (ICP) causing optic nerve atrophy if not ... ...

Abstract	Background: Idiopathic intracranial hypertension (IIH) is a rare disease of unknown aetiology related possibly to disturbed cerebrospinal fluid (CSF) dynamics and characterised by elevated intracranial pressure (ICP) causing optic nerve atrophy if not timely treated. We studied CSF dynamics of the IIH patients based on the available literature and our well-defined cohort. Method: A literature review was performed from PubMed between 1980 and 2020 in compliance with the PRISMA guideline. Our study includes 59 patients with clinical, demographical, neuro-ophthalmological, radiological, outcome data, and lumbar CSF pressure measurements for suspicion of IIH; 39 patients had verified IIH while 20 patients did not according to Friedman's criteria, hence referred to as symptomatic controls. Results: The literature review yielded 19 suitable studies; 452 IIH patients and 264 controls had undergone intraventricular or lumbar CSF pressure measurements. In our study, the mean CSF pressure, pulse amplitudes, power of respiratory waves (RESP), and the pressure constant (P Conclusions: Our literature review revealed increased CSF pressure, resistance to CSF outflow and sagittal sinus pressure (SSP) as key findings in IIH. Our study confirmed significantly higher lumbar CSF pressure and increased CSF pressure waves and RAP index in IIH when excluding patients with acetazolamide treatment. In overall, the findings reflect decreased craniospinal compliance and potentially depleted cerebral autoregulation resulting from the increased CSF pressure in IIH. The increased slow waves in patients without acetazolamide may indicate issues in autoregulation, while increased P
MeSH term(s)	Cerebrospinal Fluid Pressure ; Comorbidity ; Cranial Sinuses ; Humans ; Intracranial Hypertension/epidemiology ; Pseudotumor Cerebri
Language	English
Publishing date	2021-08-27
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	80010-7
ISSN	0942-0940 ; 0001-6268
ISSN (online)	0942-0940
ISSN	0001-6268
DOI	10.1007/s00701-021-04940-x
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Article ; Online: Changes in Finnish nursing students' nursing orientations between mid 1990s and mid-2000s.

Vanhanen-Nuutinen, Liisa / Janhonen, Sirpa / Maunu, Maija / Laukkala, Helena

Nurse education today

2012 Volume 32, Issue 5, Page(s) 490–496

Abstract: Aims: The main purpose of the study was to identify nursing students' orientations to nursing, their experiences of caring and nursing, the meaning of nursing and the expectations applied to a nursing career, and to report the changes in the ... ...

Abstract	Aims: The main purpose of the study was to identify nursing students' orientations to nursing, their experiences of caring and nursing, the meaning of nursing and the expectations applied to a nursing career, and to report the changes in the orientations between the mid-1990s and the mid-2000s. Another aim was to determine the extent to which students' age, sex, having children, pre-educational caring experiences and intentions to leave nursing might explain the changes in nursing orientations. Background: There is a worldwide shortage of nurses but at the same time there is an ever decreasing number of applicants that are entering nursing education. Young people are less interested in choosing nursing as a career option than they were one or two decades ago. Methods: A sample of 426 nursing students in 1997 and 660 students in 2006-2007 from the Universities of Applied Sciences in different parts of Finland completed a questionnaire containing questions concerning the students' background factors and 26 Likert-type statements concerning their nursing orientations. Results: The following orientations were identified: personal responsibility, idealistic nursing, selfactualization, and family centrality. Statistically significant changes were found in all of the orientations between the two periods. Fewer nursing students in the 2000s were oriented to idealistic nursing or emphasised self-actualization. Instead, there were more family centrality oriented nursing students in the mid-2000s than in the mid-1990s. Conclusions: The results reflect the changes in the student generation applying for nursing education. The results challenge nurse educators to use teaching methods that promote students' awareness of their individual nursing orientations.
MeSH term(s)	Adolescent ; Adult ; Career Choice ; Career Mobility ; Education, Nursing/trends ; Female ; Finland ; Humans ; Intention ; Male ; Middle Aged ; Nursing Education Research ; Nursing Methodology Research ; Students, Nursing/psychology ; Students, Nursing/statistics & numerical data ; Young Adult
Language	English
Publishing date	2012-07
Publishing country	Scotland
Document type	Journal Article ; Review
ZDB-ID	1062570-7
ISSN	1532-2793 ; 0260-6917
ISSN (online)	1532-2793
ISSN	0260-6917
DOI	10.1016/j.nedt.2011.08.010
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Article: Changes in students' orientations to nursing during nursing education.

Vanhanen, L / Janhonen, S

Nurse education today

2000 Volume 20, Issue 8, Page(s) 654–661

Abstract: The purpose of this study was to describe the changes that took place in students' orientations to nursing during nursing education. The theoretical background of the research lay in the model of nursing students' orientation to nursing, which defines ... ...

Abstract	The purpose of this study was to describe the changes that took place in students' orientations to nursing during nursing education. The theoretical background of the research lay in the model of nursing students' orientation to nursing, which defines students' orientations in terms of caring, nursing expertise and life orientation. The orientations differ from each other as regards the student's pre-educational caring and nursing experiences, the meaning of caring and nursing and the expectations for a career in nursing. The research was conducted qualitatively, but quantitative measures were also used. The interviews of 19 voluntary nursing students concerning their orientation to nursing both at the beginning and at the end of education were analyzed by content analysis. The categories were derived deductively from the model of nursing students' orientation to nursing. The categories were quantified, and paired t-test and Wilcoxon test were performed to test the significance of the changes in students' orientations between the beginning and the end of education.
MeSH term(s)	Education, Nursing, Baccalaureate ; Empathy ; Humans ; Longitudinal Studies ; Nursing Education Research ; Philosophy, Nursing ; Self Concept ; Students, Nursing/psychology
Language	English
Publishing date	2000-11
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	1062570-7
ISSN	1532-2793 ; 0260-6917
ISSN (online)	1532-2793
ISSN	0260-6917
DOI	10.1054/nedt.2000.0485
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Article ; Online: Buried in water, burdened by nature-Resilience carried the Iron Age people through Fimbulvinter.

Oinonen, Markku / Alenius, Teija / Arppe, Laura / Bocherens, Hervé / Etu-Sihvola, Heli / Helama, Samuli / Huhtamaa, Heli / Lahtinen, Maria / Mannermaa, Kristiina / Onkamo, Päivi / Palo, Jukka / Sajantila, Antti / Salo, Kati / Sundell, Tarja / Vanhanen, Santeri / Wessman, Anna

PloS one

2020 Volume 15, Issue 4, Page(s) e0231787

Abstract: Levänluhta is a unique archaeological site with the remains of nearly a hundred Iron Age individuals found from a water burial in Ostrobothnia, Finland. The strongest climatic downturn of the Common Era, resembling the great Fimbulvinter in Norse ... ...

Abstract	Levänluhta is a unique archaeological site with the remains of nearly a hundred Iron Age individuals found from a water burial in Ostrobothnia, Finland. The strongest climatic downturn of the Common Era, resembling the great Fimbulvinter in Norse mythology, hit these people during the 6th century AD. This study establishes chronological, dietary, and livelihood synthesis on this population based on stable carbon and nitrogen isotopic and radiocarbon analyses on human remains, supported by multidisciplinary evidence. Extraordinarily broad stable isotopic distribution is observed, indicating three subgroups with distinct dietary habits spanning four centuries. This emphasizes the versatile livelihoods practiced at this boundary of marine, freshwater, and terrestrial ecosystems. While the impact of the prolonged cold darkness of the 6th century was devastating for European communities relying on cultivation, the broad range of livelihoods provided resilience for the Levänluhta people to overcome the abrupt climatic decline.
MeSH term(s)	Agriculture/history ; Archaeology ; Bone and Bones/chemistry ; Climate Change/history ; Feeding Behavior ; Finland ; History, Ancient ; Humans ; Radiometric Dating ; Resilience, Psychological
Language	English
Publishing date	2020-04-21
Publishing country	United States
Document type	Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0231787
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Article: Factors associated with students' orientations to nursing.

Vanhanen, L / Janhonen, S

Journal of advanced nursing

2000 Volume 31, Issue 5, Page(s) 1054–1062

Abstract: Factors associated with students' orientations to nursing This paper presents the results of a study focusing on the factors associated with orientations to nursing. Students' orientations to nursing have not as yet been a focus of nursing research. In ... ...

Abstract	Factors associated with students' orientations to nursing This paper presents the results of a study focusing on the factors associated with orientations to nursing. Students' orientations to nursing have not as yet been a focus of nursing research. In some other professions, however, professional orientation has been associated with learning motivation and study performance, and has been seen as a predictor of work satisfaction. In this study, students' orientations to nursing were defined in terms of caring, nursing expertise and life orientation. The hypothesis of whether students' pre-educational experiences of nursing, gender, choice of nursing specialty, problems with nursing studies and intention to stay in nursing were associated with different orientations was tested. The extent to which students were orientated to caring, nursing expertise and their own life was also examined. The orientation to nursing measurement tool, which has been developed on the basis of a qualitative study, was used to collect the data. Nurse teachers collected the data from nursing students (n=184) who were studying in three different nursing programmes in Finland. Non-parametric assessments (Mann-Whitney U-test and Kruskal-Wallis test) of the differences between the students' orientations were carried out. A majority of the students were highly life-orientated, and two-thirds had average nursing expertise or caring orientation scores. The results supported the study hypothesis of an association between students' orientations and their gender, choice of nursing speciality, problems with nursing studies and intention to stay in nursing. However, the hypothesis of an association between students' pre-educational nursing experiences and orientation to nursing was not supported. The contradictions between students' orientation to nursing and the philosophy of nursing underlying the study programme may be a source of motivational problems and dissatisfaction with nursing education. Therefore, nurse educators are challenged to discuss curriculum matters and student supervision in order to promote flexibility in planning personal study programmes.
MeSH term(s)	Adolescent ; Adult ; Analysis of Variance ; Career Choice ; Clinical Competence ; Empathy ; Female ; Finland ; Humans ; Male ; Middle Aged ; Motivation ; Sex Factors ; Statistics, Nonparametric ; Students, Nursing/psychology
Language	English
Publishing date	2000-05-30
Publishing country	England
Document type	Journal Article
ZDB-ID	197634-5
ISSN	1365-2648 ; 0309-2402
ISSN (online)	1365-2648
ISSN	0309-2402
DOI	10.1046/j.1365-2648.2000.01390.x
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Article ; Online: Seasonal Succession of Fungi Associated with Ips typographus Beetles and Their Phoretic Mites in an Outbreak Region of Finland.

Linnakoski, Riikka / Mahilainen, Saila / Harrington, Alison / Vanhanen, Henri / Eriksson, Miikka / Mehtätalo, Lauri / Pappinen, Ari / Wingfield, Michael J

PloS one

2016 Volume 11, Issue 5, Page(s) e0155622

Abstract: The ophiostomatoid fungi (Microascales and Ophiostomatales, Ascomycota) are common associates of Ips typographus, and include tree pathogens and species responsible for blue-stain of timber. Fungal assemblages associated with I. typographus have varied ... ...

Abstract	The ophiostomatoid fungi (Microascales and Ophiostomatales, Ascomycota) are common associates of Ips typographus, and include tree pathogens and species responsible for blue-stain of timber. Fungal assemblages associated with I. typographus have varied considerably between studies but few investigations have attempted to explain this variation. For this reason, we assessed the overall cultivable fungal diversity associated with I. typographus in a storm-felled spruce forest in south-eastern Finland. Fungi were isolated from the individually collected beetles as well as their phoretic mites in spring, summer and autumn, including different life stages of the beetle (hibernation, dispersal flight and first generation). The internal transcribed spacer (ITS) gene region was used to identify the fungi. A total of 32 operational taxonomic units (OTUs) were found and these resided in four fungal phyla/subphyla (24 Ascomycota, 2 Basidiomycota, 5 Mucoromycotina, 1 Mortierellomycotina) in association with adult bark beetles. Ophiostomatoid species were the most commonly detected fungal associates. A generalized linear model analysis showed a clear association between fungal communities and season, indicating seasonal succession among I. typographus-associated fungi. The season of sampling appears to be an important factor that has resulted in inconsistencies between results in previous studies. Many of these fungi were also found on phoretic mites and their presence or absence could have influenced variation in patterns of association.
MeSH term(s)	Animals ; Coleoptera/microbiology ; Finland ; Fungi/classification ; Fungi/isolation & purification ; Mites/microbiology ; Picea/parasitology ; Seasons ; Symbiosis
Language	English
Publishing date	2016-05-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0155622
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Article ; Online: Mineral Analysis of Pine Nuts (Pinus spp.) Grown in New Zealand

Leo P. Vanhanen / Geoffrey P. Savage

Foods, Vol 2, Iss 2, Pp 143-

2013 Volume 150

Abstract: ... Pinus armandii Franch), Swiss stone pine (Pinus cembra L.), Mexican pinyon (Pinus cembroides Zucc. var ... bicolor Little), Coulter pine (Pinus coulteri D. Don), Johann’s pine (Pinus johannis M.F. Robert), Italian ... stone pine (Pinus pinea L.) and Torrey pine (Pinus torreyana Parry ex Carrière), was carried out using ...

Abstract	Mineral analysis of seven Pinus species grown in different regions of New Zealand; Armand pine (Pinus armandii Franch), Swiss stone pine (Pinus cembra L.), Mexican pinyon (Pinus cembroides Zucc. var. bicolor Little), Coulter pine (Pinus coulteri D. Don), Johann’s pine (Pinus johannis M.F. Robert), Italian stone pine (Pinus pinea L.) and Torrey pine (Pinus torreyana Parry ex Carrière), was carried out using an inductively coupled plasma optical emission spectrophotometer (ICP-OES) analysis. Fourteen different minerals (Al, B, Ca, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, P, S and Zn) were identified in all seven varieties, except that no Al or Na was found in Pinus coulteri D. Don. New Zealand grown pine nuts are a good source of Cu, Mg, Mn, P and Zn, meeting or exceeding the recommended RDI for these minerals (based on an intake of 50 g nuts/day) while they supplied between 39%–89% of the New Zealand RDI for Fe. Compared to other commonly eaten tree-nuts New Zealand grown pine nuts are an excellent source of essential minerals.
Keywords	pine nuts ; Pinus spp. ; mineral content ; diet ; Nutrition. Foods and food supply ; TX341-641 ; Home economics ; TX1-1110 ; Technology ; T ; DOAJ:Nutrition and Food Sciences ; DOAJ:Agriculture and Food Sciences
Language	English
Publishing date	2013-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Bioavailability of soluble oxalate from tea and the effect of consuming milk with the tea.

Savage, G P / Charrier, M J S / Vanhanen, L

European journal of clinical nutrition

2003 Volume 57, Issue 3, Page(s) 415–419

Abstract: Objectives: To measure the availability of oxalate normally extracted when making tea from two commercially available black teas bought from a supermarket in Christchurch, New Zealand in July 2001.: Design, subjects and intervention: A randomized ... ...

Abstract	Objectives: To measure the availability of oxalate normally extracted when making tea from two commercially available black teas bought from a supermarket in Christchurch, New Zealand in July 2001. Design, subjects and intervention: A randomized double crossover study. Six students and four staff consumed six cups of each brand of tea both with and without added milk over a 24 h period. A total urine collection was taken for the initial 6 h followed by a further 18 h. The oxalate content of the urine voided was measured using an enzyme kit method and the availability of the soluble oxalate consumed was measured for the 6 h and the total 24 h sample. Setting: University campus. Results: The mean soluble oxalate content of black tea in the two different commercial tea bags was respectively 6.1 and 6.3 mg soluble oxalate/g tea. The mean availability of the oxalate extracted from tea measured over a 6 h period ranged from 1.9 to 4.7% when tea was consumed without milk. The availability of the soluble oxalate from tea ranged from -3.0 to 2.3% for each of the two brands of tea investigated over a 24 h period. Conclusion: These studies show that consuming black tea on a daily basis will lead to a moderate intake of soluble oxalate each day, however the consumption of tea with milk on a regular basis will result in the absorption of very little oxalate from tea.
MeSH term(s)	Adult ; Animals ; Biological Availability ; Cross-Over Studies ; Female ; Humans ; Intestinal Absorption ; Male ; Middle Aged ; Milk/chemistry ; Oxalates/adverse effects ; Oxalates/pharmacokinetics ; Oxalates/urine ; Tea/chemistry
Chemical Substances	Oxalates ; Tea
Language	English
Publishing date	2003-03
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	639358-5
ISSN	1476-5640 ; 0954-3007
ISSN (online)	1476-5640
ISSN	0954-3007
DOI	10.1038/sj.ejcn.1601572
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