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  1. Article ; Online: C

    Pyankov, V I / Gunin, P D / Tsoog, S / Black, C C

    Oecologia

    2000  Volume 123, Issue 1, Page(s) 15–31

    Abstract: ... of species with C ...

    Abstract The natural geographical occurrence, carbon assimilation, and structural and biochemical diversity of species with C
    Language English
    Publishing date 2000-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123369-5
    ISSN 1432-1939 ; 0029-8549
    ISSN (online) 1432-1939
    ISSN 0029-8549
    DOI 10.1007/s004420050985
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    Z 70/109: Show issues

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  2. Article ; Online: Substrate Conformation Regulates Aromatic C-H Vs C-F Bond Activation in Heme-Dependent Tyrosine Hydroxylase.

    Singh, Warispreet / Santos, Sonia F G / Yadav, Shalini / Black, Gary W / Dubey, Kshatresh Dutta

    Biochemistry

    2023  Volume 62, Issue 10, Page(s) 1577–1587

    Abstract: ... for functionalizing the high-strength C-H and C-F bonds in aromatic compounds. However, there is ambiguity regarding ... in the functionalization of both C-F and C-H bonds. The energy barrier for C-H and C-F activation using compound 0 (Cpd 0 ... favors the C-H activation, while the other conformation prefers the C-F activation ...

    Abstract A recently discovered heme-dependent enzyme tyrosine hydroxylase (TyrH) offers a green approach for functionalizing the high-strength C-H and C-F bonds in aromatic compounds. However, there is ambiguity regarding the nature of the oxidant (compound 0 or compound I) involved in activating these bonds. Herein, using comprehensive molecular dynamics (MD) simulations and hybrid quantum mechanical/molecular mechanical calculations, we reveal that it is compound I (Cpd I) that acts as the primary oxidant involved in the functionalization of both C-F and C-H bonds. The energy barrier for C-H and C-F activation using compound 0 (Cpd 0) as an oxidant was very high, indicating that Cpd 0 cannot be an oxidant. Consistent with the previous experimental finding, our simulation shows two different conformations of the substrate, where one orientation favors the C-H activation, while the other conformation prefers the C-F activation. As such, our mechanistic study shows that nature utilizes just one oxidant, that is, Cpd I, but it is the active site conformation that decides whether it selects C-F or C-H functionalization which may resemble involvement of two different oxidants.
    MeSH term(s) Heme/chemistry ; Tyrosine 3-Monooxygenase ; Oxidants/chemistry ; Molecular Dynamics Simulation ; Catalytic Domain
    Chemical Substances Heme (42VZT0U6YR) ; Tyrosine 3-Monooxygenase (EC 1.14.16.2) ; Oxidants
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1108-3
    ISSN 1520-4995 ; 0006-2960
    ISSN (online) 1520-4995
    ISSN 0006-2960
    DOI 10.1021/acs.biochem.3c00087
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    Zs.A 217: Show issues Location:
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  3. Article ; Online: Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing.

    Liu, Jingshu / Black, Graeme C / Kimber, Susan J / Sergouniotis, Panagiotis I

    Stem cell research

    2022  Volume 64, Page(s) 102880

    Abstract: ... in melanocytes and retinal pigment epithelia (RPE). The TYR c.575C>A (p.Ser192Tyr) [rs1042602] and c.1205G>A (p ... line (WTSIi253-A-2) that carries both c.575C>A and c.1205G>A in homozygous state. The line expresses ...

    Abstract TYR encodes tyrosinase, the enzyme catalysing the first steps of melanin biosynthesis in melanocytes and retinal pigment epithelia (RPE). The TYR c.575C>A (p.Ser192Tyr) [rs1042602] and c.1205G>A (p.Arg402Gln) [rs1126809] variants are prevalent genetic changes that have been associated with multiple pigmentation traits. Notably, individuals who are homozygous for these two missense variants are predisposed to having albinism. Here we used CRISPR-Cas9 technology to generate an induced pluripotent stem cell (iPSC) line (WTSIi253-A-2) that carries both c.575C>A and c.1205G>A in homozygous state. The line expresses pluripotency markers and exhibits multi-lineage differentiation potential, providing a useful in vitro model for investigating albinism pathogenesis.
    MeSH term(s) Humans ; Gene Editing ; Induced Pluripotent Stem Cells/metabolism ; Monophenol Monooxygenase/genetics ; Monophenol Monooxygenase/metabolism ; CRISPR-Cas Systems/genetics ; Melanins/genetics ; Melanins/metabolism ; Albinism/genetics ; Retinal Pigments
    Chemical Substances Monophenol Monooxygenase (EC 1.14.18.1) ; Melanins ; Retinal Pigments
    Language English
    Publishing date 2022-07-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2022.102880
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  4. Article ; Online: Catalytic Metal-free Allylic C-H Amination of Terpenoids.

    Teh, Wei Pin / Obenschain, Derek C / Black, Blaise M / Michael, Forrest E

    Journal of the American Chemical Society

    2020  Volume 142, Issue 39, Page(s) 16716–16722

    Abstract: The selective replacement of C-H bonds in complex molecules, especially natural products like ...

    Abstract The selective replacement of C-H bonds in complex molecules, especially natural products like terpenoids, is a highly efficient way to introduce new functionality and/or couple fragments. Here, we report the development of a new metal-free allylic amination of alkenes that allows the introduction of a wide range of nitrogen functionality at the allylic position of alkenes with unique regioselectivity and no allylic transposition. This reaction employs catalytic amounts of selenium in the form of phosphine selenides or selenoureas. Simple sulfonamides and sulfamates can be used directly in the reaction without the need to prepare isolated nitrenoid precursors. We demonstrate the utility of this transformation by aminating a large set of terpenoids in high yield and regioselectivity.
    Language English
    Publishing date 2020-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.0c06997
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  5. Article ; Online: Indirect photo-electrochemical detection of carbohydrates with Pt@g-C

    Zhao, Yuanzhu / Dobson, Joshua / Harabajiu, Catajina / Madrid, Elena / Kanyanee, Tinakorn / Lyall, Catherine / Reeksting, Shaun / Carta, Mariolino / McKeown, Neil B / Torrente-Murciano, Laura / Black, Kate / Marken, Frank

    Bioelectrochemistry (Amsterdam, Netherlands)

    2020  Volume 134, Page(s) 107499

    Abstract: ... in the photocatalytic compartment by a Pt@g-C ...

    Abstract An "indirect" photo-electrochemical sensor is presented for the measurement of a mixture of analytes including reducing sugars (e.g. glucose, fructose) and non-reducing sugars (e.g. sucrose, trehalose). Its innovation relies on the use of a palladium film creating a two-compartment cell to separate the electrochemical and the photocatalytic processes. In this original way, the electrochemical detection is separated from the potential complex matrix of the analyte (i.e. colloids, salts, additives, etc.). Hydrogen is generated in the photocatalytic compartment by a Pt@g-C
    MeSH term(s) Catalysis ; Electrochemistry ; Hydrogen/chemistry ; Membranes, Artificial ; Nitriles/chemistry ; Palladium/chemistry ; Photochemical Processes ; Platinum/chemistry ; Polymers/chemistry ; Porosity ; Sugars/analysis ; Sugars/chemistry
    Chemical Substances Membranes, Artificial ; Nitriles ; Polymers ; Sugars ; Platinum (49DFR088MY) ; cyanogen (534Q0F66RK) ; Palladium (5TWQ1V240M) ; Hydrogen (7YNJ3PO35Z)
    Language English
    Publishing date 2020-03-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2010650-6
    ISSN 1878-562X ; 0302-4598 ; 1567-5394
    ISSN (online) 1878-562X
    ISSN 0302-4598 ; 1567-5394
    DOI 10.1016/j.bioelechem.2020.107499
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    Zs.A 1178: Show issues Location:
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  6. Article: Outcomes of hepatitis C virus seropositive donors to hepatitis C virus seronegative liver recipients: A large single center analysis.

    Sobotka, Lindsay A / Mumtaz, Khalid / Wellner, Michael R / Kelly, Sean G / Conteh, Lanla F / Hanje, A James / Schenk, Austin / El-Hinnawi, Ashraf / Black, Sylvester / Washburn, Kenneth / Pesavento, Todd / Daloul, Reem / Michaels, Anthony J

    Annals of hepatology

    2021  Volume 24, Page(s) 100318

    Abstract: ... the management of hepatitis C virus (HCV) infection and has led to the expansion of the deceased donor organ pool ...

    Abstract Introduction and objectives: The success of direct-acting antivirals (DAA) has transformed the management of hepatitis C virus (HCV) infection and has led to the expansion of the deceased donor organ pool for liver transplantation.
    Material and methods: We present a single center retrospective review of liver transplantations performed on HCV-seronegative recipients from HCV-seropositive organs from 11/2017 to 05/2020. HCV nucleic acid testing (NAT) was performed on HCV-seropositive donors to assess active HCV infection.
    Results: 42 HCV-seronegative recipients underwent a liver transplant from a HCV-seropositive donor, including 21 NAT negative (20 liver, 1 simultaneous liver kidney transplant) and 21 NAT positive liver transplants. Two (9.5%) HCV antibody positive/NAT negative recipients developed HCV viremia and achieved sustained virologic response with DAA therapy. The remaining patients with available data (19 patients) remained polymerase chain reaction (PCR) negative at 6 months. 20 (95%) of HCV antibody positive/NAT positive recipients had a confirmed HCV viremia. 100% of patients with available data (15 patients) achieved SVR. Observed events include 1 mortality and graft loss and equivalent rates of post-transplant complications between NAT positive and NAT negative recipients.
    Conclusions: HCV-seropositive organs can be safely transplanted into HCV-seronegative patients with minimal complications post-transplant.
    MeSH term(s) Adult ; Aged ; Antiviral Agents/therapeutic use ; Donor Selection ; Female ; Hepacivirus/isolation & purification ; Hepatitis C/diagnosis ; Hepatitis C/epidemiology ; Hepatitis C/therapy ; Humans ; Liver Diseases/diagnosis ; Liver Diseases/surgery ; Liver Diseases/virology ; Liver Transplantation ; Male ; Middle Aged ; Retrospective Studies ; Sustained Virologic Response ; Treatment Outcome
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-01-27
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    DOI 10.1016/j.aohep.2021.100318
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  7. Article ; Online: Using Public Health Surveillance Data to Determine Hepatitis C Virus Exposure Among Live-Born Infants in Tennessee, 2013-2017.

    Wingate, Heather / Sizemore, Lindsey / Black, Jennifer / Heth, Zachary / Talley, Pamela / Patrick, Stephen W / Wester, Carolyn

    Public health reports (Washington, D.C. : 1974)

    2021  Volume 137, Issue 5, Page(s) 860–866

    Abstract: Objective: Maternal hepatitis C virus (HCV) infection reported on birth certificates has been ...

    Abstract Objective: Maternal hepatitis C virus (HCV) infection reported on birth certificates has been shown to underestimate HCV infection. We sought to determine the usefulness of HCV surveillance data for (1) quantifying the number of HCV-positive reproductive-aged women with a live birth, (2) comparing maternal HCV surveillance data with reported HCV infection status on birth certificates, and (3) delineating past versus current maternal infection to identify true perinatal exposures.
    Methods: We extracted data from January 1, 2013, through December 31, 2017, on birth certificate indication of HCV exposure from the Tennessee Birth Statistical File, and we ascertained indication of HCV exposure by using laboratory data from the Tennessee National Electronic Disease Surveillance System (NEDSS) Base System (NBS). We conducted a sensitivity analysis comparing birth certificate indication of HCV exposure with HCV laboratory data to determine whether true perinatal exposure had occurred.
    Results: During the study period, 6731 mothers with live births in Tennessee reported having HCV infection during pregnancy: 3295 (49.0%) had both laboratory and birth certificate indication of HCV infection, 2130 (31.6%) had indication of HCV infection on the laboratory report only, and 1306 (19.4%) had indication of HCV infection on the birth certificate only.
    Conclusions: Using data from a public health HCV surveillance system with birth certificate data may improve the identification of HCV-infected pregnant women and perinatally exposed infants. Surveillance systems that include complete reporting of all HCV RNA results can be used to distinguish past from present maternal HCV infection to focus limited public health resources on currently infected mothers and their exposed infants.
    MeSH term(s) Adult ; Female ; Hepacivirus ; Hepatitis C/epidemiology ; Humans ; Infant ; Live Birth ; Pregnancy ; Public Health Surveillance ; Tennessee/epidemiology
    Language English
    Publishing date 2021-08-17
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 120953-x
    ISSN 1468-2877 ; 0033-3549
    ISSN (online) 1468-2877
    ISSN 0033-3549
    DOI 10.1177/00333549211035854
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  8. Article ; Online: Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing

    Jingshu Liu / Graeme C. Black / Susan J. Kimber / Panagiotis I. Sergouniotis

    Stem Cell Research, Vol 64, Iss , Pp 102880- (2022)

    2022  

    Abstract: ... in melanocytes and retinal pigment epithelia (RPE). The TYR c.575C>A (p.Ser192Tyr) [rs1042602] and c.1205G>A (p ... line (WTSIi253-A-2) that carries both c.575C>A and c.1205G>A in homozygous state. The line expresses ...

    Abstract TYR encodes tyrosinase, the enzyme catalysing the first steps of melanin biosynthesis in melanocytes and retinal pigment epithelia (RPE). The TYR c.575C>A (p.Ser192Tyr) [rs1042602] and c.1205G>A (p.Arg402Gln) [rs1126809] variants are prevalent genetic changes that have been associated with multiple pigmentation traits. Notably, individuals who are homozygous for these two missense variants are predisposed to having albinism. Here we used CRISPR-Cas9 technology to generate an induced pluripotent stem cell (iPSC) line (WTSIi253-A-2) that carries both c.575C>A and c.1205G>A in homozygous state. The line expresses pluripotency markers and exhibits multi-lineage differentiation potential, providing a useful in vitro model for investigating albinism pathogenesis.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells.

    Li, Xinyue / Kaur, Navneet / Albahrani, Mustafa / Karpf, Adam R / Black, Adrian R / Black, Jennifer D

    The Journal of biological chemistry

    2023  Volume 299, Issue 4, Page(s) 103017

    Abstract: ... Protein kinase C α (PKCα) and transforming growth factor β (TGFβ) are negative regulators of proliferation ...

    Abstract Tight coordination of growth regulatory signaling is required for intestinal epithelial homeostasis. Protein kinase C α (PKCα) and transforming growth factor β (TGFβ) are negative regulators of proliferation with tumor suppressor properties in the intestine. Here, we identify novel crosstalk between PKCα and TGFβ signaling. RNA-Seq analysis of nontransformed intestinal crypt-like cells and colorectal cancer cells identified TGFβ receptor 1 (TGFβR1) as a target of PKCα signaling. RT-PCR and immunoblot analysis confirmed that PKCα positively regulates TGFβR1 mRNA and protein expression in these cells. Effects on TGFβR1 were dependent on Ras-extracellular signal-regulated kinase 1/2 (ERK) signaling. Nascent RNA and promoter-reporter analysis indicated that PKCα induces TGFβR1 transcription, and Runx2 was identified as an essential mediator of the effect. PKCα promoted ERK-mediated activating phosphorylation of Runx2, which preceded transcriptional activation of the TGFβR1 gene and induction of Runx2 expression. Thus, we have identified a novel PKCα→ERK→Runx2→TGFβR1 signaling axis. In further support of a link between PKCα and TGFβ signaling, PKCα knockdown reduced the ability of TGFβ to induce SMAD2 phosphorylation and cell cycle arrest, and inhibition of TGFβR1 decreased PKCα-induced upregulation of p21
    MeSH term(s) Humans ; Colorectal Neoplasms/genetics ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Epithelial Cells/metabolism ; Intestines ; Protein Kinase C-alpha/genetics ; Protein Kinase C-alpha/metabolism ; RNA, Messenger/genetics ; Transforming Growth Factor beta/metabolism ; Receptor, Transforming Growth Factor-beta Type I/genetics ; Receptor, Transforming Growth Factor-beta Type I/metabolism
    Chemical Substances Core Binding Factor Alpha 1 Subunit ; Protein Kinase C-alpha (EC 2.7.11.13) ; RNA, Messenger ; RUNX2 protein, human ; Transforming Growth Factor beta ; TGFBR1 protein, human (EC 2.7.11.30) ; Receptor, Transforming Growth Factor-beta Type I (EC 2.7.11.30)
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2023.103017
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  10. Article ; Online: Observation of the B_{c}^{+} Meson in Pb-Pb and pp Collisions at sqrt[s_{NN}]=5.02  TeV and Measurement of its Nuclear Modification Factor.

    Tumasyan, A / Adam, W / Andrejkovic, J W / Bergauer, T / Chatterjee, S / Dragicevic, M / Del Valle, A Escalante / Frühwirth, R / Jeitler, M / Krammer, N / Lechner, L / Liko, D / Mikulec, I / Paulitsch, P / Pitters, F M / Schieck, J / Schöfbeck, R / Schwarz, D / Templ, S /
    Waltenberger, W / Wulz, C-E / Chekhovsky, V / Litomin, A / Makarenko, V / Darwish, M R / De Wolf, E A / Janssen, T / Kello, T / Lelek, A / Sfar, H Rejeb / Van Mechelen, P / Van Putte, S / Van Remortel, N / Blekman, F / Bols, E S / D'Hondt, J / Delcourt, M / Faham, H El / Lowette, S / Moortgat, S / Morton, A / Müller, D / Sahasransu, A R / Tavernier, S / Van Doninck, W / Van Mulders, P / Beghin, D / Bilin, B / Clerbaux, B / De Lentdecker, G / Favart, L / Grebenyuk, A / Kalsi, A K / Lee, K / Mahdavikhorrami, M / Makarenko, I / Moureaux, L / Pétré, L / Popov, A / Postiau, N / Starling, E / Thomas, L / Vanden Bemden, M / Vander Velde, C / Vanlaer, P / Wezenbeek, L / Cornelis, T / Dobur, D / Knolle, J / Lambrecht, L / Mestdach, G / Niedziela, M / Roskas, C / Samalan, A / Skovpen, K / Tytgat, M / Vermassen, B / Vit, M / Benecke, A / Bethani, A / Bruno, G / Bury, F / Caputo, C / David, P / Delaere, C / Donertas, I S / Giammanco, A / Jaffel, K / Jain, Sa / Lemaitre, V / Mondal, K / Prisciandaro, J / Taliercio, A / Teklishyn, M / Tran, T T / Vischia, P / Wertz, S / Alves, G A / Hensel, C / Moraes, A / Júnior, W L Aldá / Pereira, M Alves Gallo / Filho, M Barroso Ferreira / Malbouisson, H Brandao / Carvalho, W / Chinellato, J / Da Costa, E M / Da Silveira, G G / Damiao, D De Jesus / De Souza, S Fonseca / Figueiredo, D Matos / Herrera, C Mora / Amarilo, K Mota / Mundim, L / Nogima, H / Teles, P Rebello / Santoro, A / Amaral, S M Silva Do / Sznajder, A / Thiel, M / De Araujo, F Torres Da Silva / Pereira, A Vilela / Bernardes, C A / Calligaris, L / Tomei, T R Fernandez Perez / Gregores, E M / Lemos, D S / Mercadante, P G / Novaes, S F / Padula, Sandra S / Aleksandrov, A / Antchev, G / Hadjiiska, R / Iaydjiev, P / Misheva, M / Rodozov, M / Shopova, M / Sultanov, G / Dimitrov, A / Ivanov, T / Litov, L / Pavlov, B / Petkov, P / Petrov, A / Cheng, T / Javaid, T / Mittal, M / Yuan, L / Ahmad, M / Bauer, G / Dozen, C / Hu, Z / Martins, J / Wang, Y / Yi, K / Chapon, E / Chen, G M / Chen, H S / Chen, M / Iemmi, F / Kapoor, A / Leggat, D / Liao, H / Liu, Z-A / Milosevic, V / Monti, F / Sharma, R / Tao, J / Thomas-Wilsker, J / Wang, J / Zhang, H / Zhao, J / Agapitos, A / An, Y / Ban, Y / Chen, C / Levin, A / Li, Q / Lyu, X / Mao, Y / Qian, S J / Wang, D / Wang, Q / Xiao, J / Lu, M / You, Z / Gao, X / Okawa, H / Lin, Z / Xiao, M / Avila, C / Cabrera, A / Florez, C / Fraga, J / Guisao, J Mejia / Ramirez, F / Alvarez, J D Ruiz / González, C A Salazar / Giljanovic, D / Godinovic, N / Lelas, D / Puljak, I / Antunovic, Z / Kovac, M / Sculac, T / Brigljevic, V / Ferencek, D / Majumder, D / Roguljic, M / Starodumov, A / Susa, T / Attikis, A / Christoforou, K / Erodotou, E / Ioannou, A / Kole, G / Kolosova, M / Konstantinou, S / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Saka, H / Finger, M / Kveton, A / Ayala, E / Jarrin, E Carrera / Elgammal, S / Kamel, A Ellithi / Mahmoud, M A / Mohammed, Y / Bhowmik, S / Dewanjee, R K / Ehataht, K / 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    Physical review letters

    2022  Volume 128, Issue 25, Page(s) 252301

    Abstract: The B_{c}^{+} meson is observed for the first time in heavy ion collisions. Data from the CMS ... detector are used to study the production of the B_{c}^{+} meson in lead-lead (Pb-Pb) and proton-proton (pp ... collisions at a center-of-mass energy per nucleon pair of sqrt[s_{NN}]=5.02  TeV, via the B_{c}^{+}→(J/ψ→μ^ ...

    Abstract The B_{c}^{+} meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the B_{c}^{+} meson in lead-lead (Pb-Pb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of sqrt[s_{NN}]=5.02  TeV, via the B_{c}^{+}→(J/ψ→μ^{+}μ^{-})μ^{+}ν_{μ} decay. The B_{c}^{+} nuclear modification factor, derived from the Pb-Pb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the Pb-Pb collision centrality. The B_{c}^{+} meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma.
    Language English
    Publishing date 2022-06-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.128.252301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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