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Article: Prosthetic joint infection due to

Singh, Joya / Antony, Suresh J

Proceedings (Baylor University. Medical Center)

2019 Volume 33, Issue 1, Page(s) 97–99

Abstract: Nontuberculous mycobacteria (NTM) are a rare cause of prosthetic joint infection (PJI) that is documented to affect immunocompromised patients primarily. In this case report, we describe an immunocompetent patient with a rare case of PJI caused ... ...

Abstract	Nontuberculous mycobacteria (NTM) are a rare cause of prosthetic joint infection (PJI) that is documented to affect immunocompromised patients primarily. In this case report, we describe an immunocompetent patient with a rare case of PJI caused by
Language	English
Publishing date	2019-10-14
Publishing country	United States
Document type	Case Reports
ZDB-ID	2703932-8
ISSN	1525-3252 ; 0899-8280
ISSN (online)	1525-3252
ISSN	0899-8280
DOI	10.1080/08998280.2019.1674089
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Article ; Online: Legionella pneumophila Pneumonia in Pregnancy: A Case Report and Review of the Literature.

Kleinberg, Katherine A / Antony, Suresh J

Infectious disorders drug targets

2019 Volume 20, Issue 2, Page(s) 247–252

Abstract: L. pneumophila is an unusual cause of pneumonia with a prevalence of 2.7%, and it is even more uncommon in pregnancy. To date, only 11 cases of Legionnaire's Disease in pregnancy have been reported, though this small number could possibly be attributed ... ...

Abstract	L. pneumophila is an unusual cause of pneumonia with a prevalence of 2.7%, and it is even more uncommon in pregnancy. To date, only 11 cases of Legionnaire's Disease in pregnancy have been reported, though this small number could possibly be attributed to underdiagnoses and under documentation. Case Presentation: In this paper, we present a 31-year-old Hispanic female, gravida 4, para 1 from the southwest United States who presented with a 3-week history of fever, worsening cough, dyspnea on exertion, and hypoxemia. Chest x-ray showed bibasilar infiltrates, with positive serology for Legionella IgM and IgG (1:250 and 1:640 respectively), as well as positive urinary antigen. Despite appropriate treatment with azithromycin 500 mg, she continued to have dyspnea and mild respiratory distress. Conclusion: Upon follow up, mother and fetus initially remained stable without any signs of sequelae from Legionnaire's disease, but the patient miscarried 5 weeks after the second admission to the hospital. The chest x-ray eventually cleared up after almost 21 days of azithromycin.
MeSH term(s)	Abortion, Spontaneous ; Adult ; Anti-Bacterial Agents/therapeutic use ; Antibodies, Bacterial/blood ; Azithromycin/therapeutic use ; Female ; Humans ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Legionella pneumophila ; Legionnaires' Disease/complications ; Legionnaires' Disease/diagnostic imaging ; Legionnaires' Disease/drug therapy ; Pneumonia, Bacterial/complications ; Pneumonia, Bacterial/diagnostic imaging ; Pneumonia, Bacterial/drug therapy ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/microbiology ; Prevalence ; Radiography
Chemical Substances	Anti-Bacterial Agents ; Antibodies, Bacterial ; Immunoglobulin G ; Immunoglobulin M ; Azithromycin (83905-01-5)
Language	English
Publishing date	2019-01-18
Publishing country	United Arab Emirates
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526519666190119110657
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Zs.A 5598: Show issues

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Article ; Online: Catheter related line sepsis resulting from Mycobacterium chelonae infection in an immunocompromised host.

Antony, Suresh J

Infectious disorders drug targets

2015 Volume 15, Issue 2, Page(s) 135–137

Abstract: Almost any species of non tuberculosis mycobacterium [NTM], including M. chelonae may be associated with nosocomial infections including catheter related sepsis, pneumonia etc. We present a case of catheter related sepsis due to M. chelonae which was ... ...

Abstract	Almost any species of non tuberculosis mycobacterium [NTM], including M. chelonae may be associated with nosocomial infections including catheter related sepsis, pneumonia etc. We present a case of catheter related sepsis due to M. chelonae which was treated with appropriate therapy including removal of the catheter. This case serves as a reminder to include the NTM group in the differential diagnosis of these nosocomial infections.
MeSH term(s)	Adult ; Catheter-Related Infections/diagnosis ; Catheter-Related Infections/drug therapy ; Catheter-Related Infections/microbiology ; Ciprofloxacin/therapeutic use ; Clarithromycin/therapeutic use ; Cross Infection/diagnosis ; Cross Infection/drug therapy ; Cross Infection/microbiology ; Drug Therapy, Combination ; Female ; Humans ; Immunocompromised Host ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/drug therapy ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium chelonae/isolation & purification ; Mycobacterium chelonae/pathogenicity ; Ovarian Neoplasms/complications ; Ovarian Neoplasms/therapy ; Sepsis/drug therapy ; Sepsis/microbiology ; Vascular Access Devices/microbiology
Chemical Substances	Ciprofloxacin (5E8K9I0O4U) ; Clarithromycin (H1250JIK0A)
Language	English
Publishing date	2015-07-23
Publishing country	United Arab Emirates
Document type	Case Reports ; Journal Article
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526515666150724114724
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Article ; Online: Coccidioidomycosis Resulting in a Prosthetic Joint Infection in an Immunocompetent Patient after a Total Hip Arthroplasty: A Case Report and Review of the Literature.

Shah, Sidra / Haq, Syed / Antony, Suresh J

Infectious disorders drug targets

2020 Volume 22, Issue 2, Page(s) e170322188282

Abstract: Introduction/background: Coccidioidomycosis is a fungal infection that is a rare cause of prosthetic joint infection (PJI) in patients.: Case presentation: This case report describes an immunocompetent patient who had a right total hip arthroplasty ( ... ...

Abstract	Introduction/background: Coccidioidomycosis is a fungal infection that is a rare cause of prosthetic joint infection (PJI) in patients. Case presentation: This case report describes an immunocompetent patient who had a right total hip arthroplasty (THA) complicated with Coccidioidomycosis. This patient is the 9th reported case of Coccidioidomycosis, causing a PJI and only the second case to be reported in a THA. Once progressed, it can be difficult to treat, often reoccurring and requiring repeat surgical and prolonged therapy. Conclusion: This study discusses the clinical presentation in this patient and reviews the literature on the currently published cases.
MeSH term(s)	Arthritis, Infectious ; Arthroplasty, Replacement, Hip/adverse effects ; Coccidioidomycosis/complications ; Coccidioidomycosis/drug therapy ; Hip Prosthesis/adverse effects ; Humans ; Prosthesis-Related Infections/drug therapy ; Prosthesis-Related Infections/surgery ; Retrospective Studies ; Risk Factors
Language	English
Publishing date	2020-07-10
Publishing country	United Arab Emirates
Document type	Case Reports ; Review
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526520999201123205249
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Article ; Online: Case series describing an outbreak of highly resistant vancomycin Staphylococcus aureus (possible VISA/VRSA) infections in orthopedic related procedures in Guatemala.

Antony, Suresh J

Infectious disorders drug targets

2014 Volume 14, Issue 1, Page(s) 44–48

Abstract: This is a case series describing an outbreak of VRSA/VISA associated infections in orthopedic related procedures that occurred on a medical mission trip in Antigua, Guatemala. The paper describes the clinical features, microbiology and treatment options ... ...

Abstract	This is a case series describing an outbreak of VRSA/VISA associated infections in orthopedic related procedures that occurred on a medical mission trip in Antigua, Guatemala. The paper describes the clinical features, microbiology and treatment options available to treat such infections in a Third World country. It also highlights the difficulty in making an accurate diagnosis with suboptimal microbiological support.
MeSH term(s)	Adult ; Amputation ; Anti-Bacterial Agents/therapeutic use ; Arthroplasty, Replacement, Knee/adverse effects ; Combined Modality Therapy ; Cross Infection/diagnosis ; Cross Infection/microbiology ; Cross Infection/therapy ; Debridement ; Developing Countries ; Disease Outbreaks ; Fracture Fixation, Internal/adverse effects ; Guatemala ; Health Services Accessibility ; Humans ; Male ; Medical Missions ; Microbial Sensitivity Tests ; Osteomyelitis/diagnosis ; Osteomyelitis/microbiology ; Osteomyelitis/therapy ; Reoperation ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/microbiology ; Staphylococcal Infections/therapy ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/pathogenicity ; Surgical Wound Infection/diagnosis ; Surgical Wound Infection/microbiology ; Surgical Wound Infection/therapy ; Treatment Outcome ; Vancomycin Resistance ; Young Adult
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2014-05-02
Publishing country	United Arab Emirates
Document type	Case Reports ; Journal Article
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526514666140522115220
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Article ; Online: Are coinfections with COVID-19 and influenza low or underreported? An observational study examining current published literature including three new unpublished cases.

Antony, Suresh J / Almaghlouth, Nouf K / Heydemann, Emily L

Journal of medical virology

2020 Volume 92, Issue 11, Page(s) 2489–2497

Abstract: As the coronavirus disease-2019 (COVID-19) pandemic continues, one major point of uncertainty is the impact this novel pathogen will have during the upcoming 2020 to 2021 flu season. While the influenza virus is a known contributor to human morbidity and ...

Abstract	As the coronavirus disease-2019 (COVID-19) pandemic continues, one major point of uncertainty is the impact this novel pathogen will have during the upcoming 2020 to 2021 flu season. While the influenza virus is a known contributor to human morbidity and mortality, the question of how a coinfection between COVID-19 and influenza might manifest is of utmost concern. The aim of this study was to review the limited cases of COVID-19/influenza coinfection currently available in the literature, along with cases in the community of El Paso, TX, to determine whether any patterns of clinical presentation and morbidity emerged. An international review of the literature was conducted. Six published articles describing COVID-19/influenza coinfection were identified, with a total of 13 patients described therein. Three additional patients were identified from the El Paso, TX data. The most common presenting symptoms were fever and cough. The most common laboratory findings were elevated C-reactive protein and lymphocytopenia. Thirteen patients presented with viral pneumonia findings on CT, and nine had findings of ground-glass opacity. Finally, complications were reported in six patients, with most common complication being acute respiratory distress syndrome. The results of the review indicate that, due to the similarity in presentation between COVID-19 and influenza, further analysis will be required to understand the effects of coinfection on morbidity and mortality. However, the limited number of coinfection cases in the literature indicates that the implementation of COVID-19 control measures may continue to play a role in limiting the spread of these human respiratory pathogens.
MeSH term(s)	Adult ; Aged ; COVID-19/epidemiology ; COVID-19/mortality ; Coinfection/epidemiology ; Coinfection/mortality ; Coinfection/virology ; Female ; Humans ; Influenza, Human/epidemiology ; Male ; Middle Aged ; Texas/epidemiology ; Tomography, X-Ray Computed
Keywords	covid19
Language	English
Publishing date	2020-06-29
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.26167
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Article ; Online: Use of Oritavancin (Novel New Lipoglycopeptide) in the Treatment of Prosthetic Joint Infections (PJI): A Possible Alternative Novel Approach to a Difficult Problem.

Antony, Suresh J / Cooper, Leigh G

Infectious disorders drug targets

2017 Volume 17, Issue 2, Page(s) 77–80

Abstract: Prosthetic joint infections (PJI) result in significant morbidity, mortality and cost to patients and the health system. Traditional treatment involves a twostaged revision and occasionally a single staged revision along with intravenous antibiotics (IV) ...

Abstract	Prosthetic joint infections (PJI) result in significant morbidity, mortality and cost to patients and the health system. Traditional treatment involves a twostaged revision and occasionally a single staged revision along with intravenous antibiotics (IV) and or oral antibiotics for several weeks to months. The use of a single staged revision along with an antibiotic which has a prolonged half life and is bactericidal would be ideal. We present 2 patients who were treated successfully with a single stage revision/antibiotic spacer and a new novel long acting lipoglycopeptide called oritavancin.
Language	English
Publishing date	2017
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526517666161108130148
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Article ; Online: Is There Enough Evidence to Avoid Remdesivir Use in Patients with Severe Renal Impairment? A Review of the Pharmacological and Clinical Literature

Suresh J. ANTONY / Emily L. HEYDEMANN / Katrina M. BROWN

Mediterranean Journal of Infection, Microbes and Antimicrobials, Vol 10, Iss

2021 Volume 1

Abstract: Although patients with severe renal impairment (SRI) typically experience more critical symptoms once infected with novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2, this population has often been excluded from randomized controlled ... ...

Abstract	Although patients with severe renal impairment (SRI) typically experience more critical symptoms once infected with novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2, this population has often been excluded from randomized controlled trials (RCT) for Coronavirus disease-2019 (COVID-19) treatment strategies. Of particular note, all RCTs for remdesivir (Veklury®), the only antiviral treatment approved by the Food and Drug Administration for COVID-19 intervention, excluded patients with an estimated glomerular filtration rate less than 30 ml/min. Regardless, some physicians have ventured to utilize this drug on patients with SRI, positing that the benefits might outweigh the risks of its use. The intent of this literature review was to examine the pharmacology of remdesivir and evaluate the published clinical literature on the topic to determine more definitively whether it might be safe to use in this population. A total of 59 articles were evaluated, seven of which contained descriptions of SRI patients treated with remdesivir for COVID-19, for a total of 176 patients. Interestingly, none of the patients experienced severe adverse reactions attributable to the use of remdesivir, and none of the investigators recommended against its use. While there is not yet clear evidence to suggest improvement in mortality, decreased morbidity and duration of illness are likely to lower mortality rates among these patients. Therefore, these findings suggest that, for patients with SRI diagnosed with COVID-19, the benefits of using remdesivir likely outweigh the risks. RCTs are urgently needed to further elucidate outcomes among this population.
Keywords	remdesivir ; covid-19 ; severe renal impairment ; end stage renal disease ; therapeutics ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
Subject code	610
Language	Turkish
Publishing date	2021-12-01T00:00:00Z
Publisher	Galenos Yayinevi
Document type	Article ; Online
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Article: Early use of tocilizumab in respiratory failure associated with acute COVID -19 pneumonia in recipients with solid organ transplantation.

Antony, Suresh J / Singh, Joya / de Jesus, Mikhail / Lance, Jessalyn

IDCases

2020 Volume 21, Page(s) e00888

Abstract: As of May 14, 2020, the World Health Organization has reported approximately 4.3 million cases of the novel Coronavirus Disease (COVID-19) with approximately 294,046 deaths worldwide [1]. Solid organ transplant recipients who are on chronic ... ...

Abstract	As of May 14, 2020, the World Health Organization has reported approximately 4.3 million cases of the novel Coronavirus Disease (COVID-19) with approximately 294,046 deaths worldwide [1]. Solid organ transplant recipients who are on chronic immunosuppressants fall within a special population of COVID-19 patients since they are more susceptible to complications secondary to COVID-19. Currently, we do not have data on treating COVID-19 patients with solid organ transplants with tocilizumab, an interleukin-6 (IL-6) inhibitor. We report a case of COVID-19 in a patient with a kidney and liver transplant and discuss the early use of tocilizumab to prevent the cytokine storm and attempt to reduce the likelihood of progression to Acute Respiratory Distress Syndrome (ARDS). In addition, we present other COVID-19 related transplant cases reported in the literature outlining the presenting clinical signs and outcomes.
Keywords	covid19
Language	English
Publishing date	2020-06-26
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2745454-X
ISSN	2214-2509
ISSN	2214-2509
DOI	10.1016/j.idcr.2020.e00888
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Article ; Online: Are coinfections with COVID‐19 and influenza low or underreported? An observational study examining current published literature including three new unpublished cases

Antony, Suresh J. / Almaghlouth, Nouf K. / Heydemann, Emily L.

Journal of Medical Virology

2020 Volume 92, Issue 11, Page(s) 2489–2497

Keywords	Virology ; Infectious Diseases ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.26167
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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