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Article ; Online: Let's Look Right during Diastolic Dysfunction Evaluation?

Foppa, Murilo / Santos, Angela Barreto Santiago

2019 Volume 112, Issue 3, Page(s) 258–259

MeSH term(s)	Atrial Appendage ; Atrial Fibrillation ; Echocardiography ; Heart Atria ; Humans ; Ventricular Function, Right
Language	Portuguese
Publishing date	2019-01-07
Publishing country	Brazil
Document type	Editorial ; Comment
ZDB-ID	730261-7
ISSN	1678-4170 ; 0066-782X
ISSN (online)	1678-4170
ISSN	0066-782X
DOI	10.5935/abc.20190053
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Article ; Online: Left ventricular structural abnormalities in the assessment of diastolic function in the elderly: source of discrepancies between the 2009 and 2016 criteria.

Gonzalez, Vinícius Leite / Santos, Angela Barreto Santiago / Rohde, Luis Eduardo Paim / Foppa, Murilo

The international journal of cardiovascular imaging

2023 Volume 39, Issue 11, Page(s) 2127–2137

Abstract: Diastolic dysfunction (DD) is routinely evaluated in echocardiography to support diagnosis, prognostication, and management of heart failure, a condition highly prevalent in elderly patients. Clinical guidelines were published in 2009, and updated in ... ...

Abstract	Diastolic dysfunction (DD) is routinely evaluated in echocardiography to support diagnosis, prognostication, and management of heart failure, a condition highly prevalent in elderly patients. Clinical guidelines were published in 2009, and updated in 2016, pursuing to standardize and improve DD categorization. We aimed to assess the concordance of DD between these two documents in an elderly population and to investigate how left ventricular structural abnormalities (LVSA) impact the reclassification. To evaluate this we analyzed the 308 consecutive transthoracic echocardiograms in patients older than 60 years (70.4 ± 7.7 years-old, 59% women) that fulfilled the inclusion criteria out of the 1438 echocardiograms performed in a tertiary hospital. We found that the prevalence of DD was lower according to the 2016 criteria (64% vs. 91%; p < 0.001), with 207 (67.2%) patients changing category, indicating poor agreement between the guidelines (kappa = 0.21). There were 188 (61%) patients with LVSA, which drove most of the reclassifications in 2016 Grade I DD cases. The prevalence of elevated filling pressures by Doppler halved in this elderly population using the updated recommendations (20.9% vs. 39.2%; p < 0.001). In conclusion the prevalence of DD was lower applying the 2016 guidelines, with a poor agreement with 2009 guidelines in all DD grades. The role of LVSA in reclassifications was particularly evident in Grade I DD, while Doppler parameters drove reclassifications among the more severe grades. If not properly addressed, these discrepancies may undermine the reliance on DD as a diagnostic and prognostic tool, particularly in an elderly population at a higher risk of heart failure.
MeSH term(s)	Humans ; Female ; Aged ; Middle Aged ; Male ; Ventricular Function, Left ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/epidemiology ; Predictive Value of Tests ; Echocardiography ; Cardiomyopathies ; Heart Failure/diagnostic imaging ; Heart Failure/epidemiology ; Heart Defects, Congenital ; Diastole
Language	English
Publishing date	2023-08-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-023-02919-6
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Article ; Online: Reproducibility of right ventricular function by longitudinal strain and other echocardiographic parameters in the ELSA-Brasil study.

Pianca, Eduardo G / Schmitz, Giulia B / Duncan, Bruce B / Foppa, Murilo / Santos, Angela B S

The international journal of cardiovascular imaging

2023 Volume 39, Issue 10, Page(s) 1865–1870

Abstract: Right ventricular (RV) free wall longitudinal strain (RVFWLS), and four-chamber longitudinal strain (RV4CLS) using speckle tracking echocardiography have demonstrated increased accuracy and discrimination to measure right ventricular function in ... ...

Abstract	Right ventricular (RV) free wall longitudinal strain (RVFWLS), and four-chamber longitudinal strain (RV4CLS) using speckle tracking echocardiography have demonstrated increased accuracy and discrimination to measure right ventricular function in different clinical conditions. Reproducibility data of these measures are scarce and mainly tested in small or reference populations. The main objective of this study was to investigate their reproducibility, and of other traditional RV parameters, from unselected participants of a large cohort study. RV strain reproducibility was analyzed using echocardiographic images of 50 participants from a randomly selected sample from The ELSA-Brasil Cohort. Images were acquired and analyzed following the study protocols. The mean RVFWLS was - 26.9 ± 2.6% and the mean RV4CLS was - 24.4 ± 1.9%. The intra-observer reproducibility parameters of RVFWLS demonstrated a coefficient of variation (CV) of 5.1% and an intraclass correlation coefficient (ICC [95%CI] 0.78[0.67-0.89]), and for RV4CLS were CV = 5.1% and ICC = 0.78[0.67-0.89]. Reproducibility for RV fractional area change was CV = 12.1%; ICC = 0.66 [0.50-0.81] and for RV basal diameter was CV = 6.3%; ICC = 0.82 [0.73-0.91]. The inter-observer reproducibility for RVFWLS was CV = 8.3%; ICC 0.54[0.34-0.74] and for RV4CLS, CV = 6.3%; ICC = 0.53[0.34-0.73], following the same pattern among conventional RV parameters. We found adequate reproducibility of RV longitudinal strain parameters. This information is relevant for the long-term follow-up of cohort participants and reinforces the utility of RV longitudinal strain as a tool to monitor subclinical changes in RV systolic function.
Language	English
Publishing date	2023-06-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-023-02899-7
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Article: Increased Mobility of the Atrial Septum in Aortic Root Dilation: An Observational Study on Transesophageal Echocardiography.

Heidemann, Altair / Dall'Oglio, Lorença / Bertoldi, Eduardo Gehling / Foppa, Murilo

Frontiers in physiology

2021 Volume 12, Page(s) 701399

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-08-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2021.701399
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Article ; Online: Myocardial iron content by T2 Star cardiac magnetic resonance and serum markers of iron metabolism in patients with heart failure.

Pereira, Guilherme Augusto Reissig / Foppa, Murilo / Eifer, Diego André / Beck-da-Silva, Luís

Journal of cardiovascular medicine (Hagerstown, Md.)

2021 Volume 23, Issue 1, Page(s) e33–e35

MeSH term(s)	Biomarkers/blood ; Cross-Sectional Studies ; Female ; Ferritins/blood ; Heart Failure/diagnostic imaging ; Hemoglobins/analysis ; Humans ; Iron/metabolism ; Magnetic Resonance Imaging, Cine ; Male ; Middle Aged ; Myocardium/metabolism ; Stroke Volume ; Transferrin/analysis
Chemical Substances	Biomarkers ; Hemoglobins ; Transferrin ; Ferritins (9007-73-2) ; Iron (E1UOL152H7)
Language	English
Publishing date	2021-09-15
Publishing country	United States
Document type	Letter
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000001263
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Zs.A 5210: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 559: Show issues

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Article ; Online: Prognostic value of right ventricular strain and peak oxygen consumption in heart failure with reduced ejection fraction.

Menegazzo, Willian Roberto / Santos, Angela Barreto Santiago / Foppa, Murilo / Scolari, Fernando Luis / Barros, Fernando Colares / Stein, Ricardo / da Silveira, Anderson Donelli

The international journal of cardiovascular imaging

2022 Volume 39, Issue 3, Page(s) 501–509

Abstract: Our purpose is to evaluate the combined predictive value of cardiopulmonary exercise testing (CPET) and echocardiographic evidence of left ventricular (LV) and right ventricular (RV) strain in predicting mortality and heart transplant (HTx) in a series ... ...

Abstract	Our purpose is to evaluate the combined predictive value of cardiopulmonary exercise testing (CPET) and echocardiographic evidence of left ventricular (LV) and right ventricular (RV) strain in predicting mortality and heart transplant (HTx) in a series of outpatients with heart failure with reduced ejection fraction (HFrEF). A retrospective cohort study of 66 patients with HFrEF (median age, 57 years; 51% women) who underwent CPET and echocardiography (up to 90 days apart) to assess prognosis. The primary outcome was a composite of death and need for HTx. At a median follow-up of 27 [20-39] months, 19 patients (29%) experienced the primary outcome. In unadjusted analysis, most echocardiographic and CPET parameters were associated with the primary outcome, including percentage of predicted peak oxygen consumption (ppVO
MeSH term(s)	Humans ; Female ; Middle Aged ; Male ; Heart Failure ; Prognosis ; Stroke Volume ; Retrospective Studies ; Predictive Value of Tests ; Ventricular Dysfunction, Left ; Oxygen Consumption
Language	English
Publishing date	2022-11-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-022-02747-0
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Article ; Online: Splenic Switch-Off for Stress Cardiovascular MR Imaging and Dipyridamole.

Torres, Felipe Soares / Foppa, Murilo

Radiology

2015 Volume 277, Issue 2, Page(s) 613–614

MeSH term(s)	Adenosine ; Cardiac Imaging Techniques/methods ; Dobutamine ; Exercise Test/methods ; Humans ; Magnetic Resonance Angiography ; Purines ; Pyrazoles ; Spleen/physiology
Chemical Substances	Purines ; Pyrazoles ; Dobutamine (3S12J47372) ; Adenosine (K72T3FS567)
Language	English
Publishing date	2015-11
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.2015151067
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Article: Effects of Antihypertensive Treatment on Left and Right Ventricular Global Longitudinal Strain and Diastolic Parameters in Patients with Hypertension and Obstructive Sleep Apnea: Randomized Clinical Trial of Chlorthalidone plus Amiloride vs. Amlodipine.

Jorge, Juliano A / Foppa, Murilo / Santos, Angela B S / Cichelero, Fábio T / Martinez, Denis / Lucca, Marcelo B / de Oliveira, Geórgia P F / Fuchs, Flávio D / Fuchs, Sandra C

Journal of clinical medicine

2023 Volume 12, Issue 11

Abstract: Hypertension is highly prevalent in patients with obstructive sleep apnea (OSA), and fluid retention with its nighttime rostral distribution is one potential mechanism. We tested whether or not diuretics differ from amlodipine in their impact on ... ...

Abstract	Hypertension is highly prevalent in patients with obstructive sleep apnea (OSA), and fluid retention with its nighttime rostral distribution is one potential mechanism. We tested whether or not diuretics differ from amlodipine in their impact on echocardiographic parameters. Patients with moderate OSA and hypertension were randomized to receive diuretics (chlorthalidone plus amiloride) or amlodipine daily for 8 weeks. We compared their effects on left and right ventricular global longitudinal strain (LV-GLS and RV-GLS, respectively), on LV diastolic parameters, and on LV remodeling. In the 55 participants who had echocardiographic images feasible for strain analysis, all echocardiographic parameters were within normal ranges. After 8 weeks, the 24 h blood pressure (BP) reduction values were similar, while most echocardiographic metrics were kept unchanged, except for LV-GLS and LV mass. In conclusion, the use of diuretics or amlodipine had small and similar effects on echocardiographic parameters in patients with moderate OSA and hypertension, suggesting that they do not have important effects on mediating the interaction between OSA and hypertension.
Language	English
Publishing date	2023-05-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12113785
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Article ; Online: Associations Between Coronary Artery Calcification and Left Ventricular Global Longitudinal Strain and Diastolic Parameters: the ELSA-Brasil Study.

Haas, Priscila / Santos, Angela B S / Cañon-Montañez, Wilson / Bittencourt, Marcio S / Torres, Felipe S / Ribeiro, Antonio L P / Duncan, Bruce B / Foppa, Murilo

The American journal of cardiology

2023 Volume 204, Page(s) 215–222

Abstract: Atherosclerosis burden can be evaluated in asymptomatic patients by measuring coronary artery calcification (CAC), whereas the global longitudinal strain (GLS) and diastolic function parameters (mitral E/e' ratio, septal e', and lateral e') are used to ... ...

Abstract	Atherosclerosis burden can be evaluated in asymptomatic patients by measuring coronary artery calcification (CAC), whereas the global longitudinal strain (GLS) and diastolic function parameters (mitral E/e' ratio, septal e', and lateral e') are used to evaluate subclinical left ventricular (LV) dysfunction. We investigated whether subjects with CAC (CAC >0 Agatston units) would present with an impairment in LV functional parameters. Among the participants of the ELSA-Brasil cohort free of clinically prevalent cardiovascular disease who performed cardiac computed tomography and echocardiography within the study protocol, we tested whether those with CAC >0 presented with worse GLS and diastolic function parameters. CAC >0 was present in 203 of the 612 included participants (33.17%; age 51.4 ± 8.6 years, 52.1% women). Absolute CAC values did not correlate with GLS (ro = 0.07, p = 0.105) but did so with E/e' (ro = 0.19, p <0.001), septal e' (ro = 0.28, p <0.001), and lateral e' (ro = 0.30, p <0.001), with stronger correlations in men. Those with CAC >0 had worse mitral E/e' ratios (7.75 ± 0.13 vs 7.01 ± 0.09; p ≤0.001), septal e' (8.25 ± 0.15 vs 9.59 ± 0.11 cm/s; p <0.001), and lateral e' (10.13 ± 0.20 vs 11.99 ± 0.14 cm/s; p ≤0.001), respectively. However, these associations were not independent of diabetes, obesity, hypertension, smoking, and low-density lipoprotein cholesterol, persisting only as significant associations of CAC >0 with mitral E/e' ratio and septal e' in men. There is an association between subclinical coronary atherosclerosis and impaired LV functional parameters. These associations are more likely attributed to the presence of common cardiovascular risk factors in the general population. However, in men, it seems to exist as an independent association.
MeSH term(s)	Male ; Humans ; Female ; Adult ; Middle Aged ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/complications ; Global Longitudinal Strain ; Echocardiography ; Diastole ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/epidemiology ; Ventricular Dysfunction, Left/etiology ; Ventricular Function, Left
Language	English
Publishing date	2023-08-07
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.06.124
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Article ; Online: Regarding effects of bariatric surgery on left ventricular mass index and geometry.

Chuang, Michael L / Foppa, Murilo

American journal of hypertension

2014 Volume 27, Issue 7, Page(s) 991–992

MeSH term(s)	Bariatric Surgery ; Female ; Heart Ventricles/pathology ; Humans ; Hypertrophy, Left Ventricular/physiopathology ; Male ; Obesity, Morbid/surgery ; Ultrasonography ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Function, Left
Language	English
Publishing date	2014-07
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	639383-4
ISSN	1941-7225 ; 1879-1905 ; 0895-7061
ISSN (online)	1941-7225 ; 1879-1905
ISSN	0895-7061
DOI	10.1093/ajh/hpu054
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