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  1. Article ; Online: Takotsubo syndrome in a premenopausal patient.

    Menezes, Maria / Marto, Daniela / Marcão, Isabel / Salvado, Catarina

    BMJ case reports

    2018  Volume 2018

    Abstract: Takotsubo syndrome is a rare clinical condition, with a pathophysiology that is not fully understood. Characterised by an acute and usually reversible heart failure, the condition is often preceded by a stressful event. For the diagnosis of Takotsubo ... ...

    Abstract Takotsubo syndrome is a rare clinical condition, with a pathophysiology that is not fully understood. Characterised by an acute and usually reversible heart failure, the condition is often preceded by a stressful event. For the diagnosis of Takotsubo syndrome to be possible, the absence of coronary artery disease as a cause is required. We report a case of Takotsubo syndrome in a 47-year-old woman of fertile age. Electrical and echocardiographic presentations were classical in the patient. However, abnormally elevated cardiac biomarkers were registered. The patient showed signs of clinical improvement, with a follow-up angiography excluding coronary artery disease and therefore leading to a diagnosis of Takotsubo syndrome.
    MeSH term(s) Acute Disease ; Biomarkers/blood ; Coronary Angiography ; Diagnosis, Differential ; Electrocardiography ; Female ; Heart Ventricles/diagnostic imaging ; Humans ; Middle Aged ; Natriuretic Peptide, Brain/blood ; Premenopause ; Respiration, Artificial ; Takotsubo Cardiomyopathy/diagnostic imaging ; Takotsubo Cardiomyopathy/physiopathology ; Troponin I/blood
    Chemical Substances Biomarkers ; Troponin I ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2018-02-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2017-222598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hidradenocarcinoma do Escroto com Metastização Ganglionar.

    Simões, Maria Inês / Marcão, Isabel / Toscano, Mário / Borges, Luís

    Acta medica portuguesa

    2018  Volume 31, Issue 3, Page(s) 176–179

    Abstract: Hidradenocarcinoma is a rare neoplasm of the eccrine cells of the sweat glands, usually asymptomatic with slow growing and higher incidence between 50 and 80 years, occurring in both sexes and preferentially located in the palmar, plantar, frontal, ... ...

    Title translation Hidradenocarcinoma of the Scrotum with Lymph Node Metastasis.
    Abstract Hidradenocarcinoma is a rare neoplasm of the eccrine cells of the sweat glands, usually asymptomatic with slow growing and higher incidence between 50 and 80 years, occurring in both sexes and preferentially located in the palmar, plantar, frontal, axillary and nuchal regions. It has an aggressive behavior, with high rate of local recurrence and distance metastasis, associated with a poor prognosis. We present a case of hidradenocarcinoma of the scrotum manifested by lymph node metastasis through an exercise of clinical and histological differential diagnosis of an inguinal adenopathy in a young adult.
    MeSH term(s) Acrospiroma/pathology ; Acrospiroma/surgery ; Adult ; Genital Neoplasms, Male/pathology ; Genital Neoplasms, Male/surgery ; Humans ; Lymphatic Metastasis ; Male ; Scrotum ; Sweat Gland Neoplasms/pathology ; Sweat Gland Neoplasms/surgery
    Language Portuguese
    Publishing date 2018-03-29
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
    DOI 10.20344/amp.9017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hidradenocarcinoma of the Scrotum with Lymph Node Metastasis

    Maria Inês Simões / Isabel Marcão / Mário Toscano / Luís Borges

    Acta Médica Portuguesa, Vol 31, Iss 3, Pp 176-

    2018  Volume 179

    Abstract: Hidradenocarcinoma is a rare neoplasm of the eccrine cells of the sweat glands, usually asymptomatic with slow growing and higher incidence between 50 and 80 years, occurring in both sexes and preferentially located in the palmar, plantar, frontal, ... ...

    Abstract Hidradenocarcinoma is a rare neoplasm of the eccrine cells of the sweat glands, usually asymptomatic with slow growing and higher incidence between 50 and 80 years, occurring in both sexes and preferentially located in the palmar, plantar, frontal, axillary and nuchal regions. It has an aggressive behavior, with high rate of local recurrence and distance metastasis, associated with a poor prognosis. We present a case of hidradenocarcinoma of the scrotum manifested by lymph node metastasis through an exercise of clinical and histological differential diagnosis of an inguinal adenopathy in a young adult.
    Keywords Adenocarcinoma ; Escroto ; Metástase Linfática ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2018-03-01T00:00:00Z
    Publisher Ordem dos Médicos
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Adenoma paratiroideu ectópico. caso clínico.

    Simões, Inês / Marcão, Isabel / Alves, Elisabette / Reis, João / Martelo, Fernando

    Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular

    2013  Volume 20, Issue 4, Page(s) 207–210

    Abstract: Ectopic parathyroid adenoma is a rare cause of primary hyperparathyroidism and can become a diagnostic challenge. We present a case report of an ectopic mediastinal parathyroid adenoma leading to primary hyperparathyroidism and responsible for a ... ...

    Title translation Ectopic parathyroid adenoma.
    Abstract Ectopic parathyroid adenoma is a rare cause of primary hyperparathyroidism and can become a diagnostic challenge. We present a case report of an ectopic mediastinal parathyroid adenoma leading to primary hyperparathyroidism and responsible for a persistent asymptomatic hypercalcemia. The preoperative location of the tumor assessed by imaging studies contribute to the choice of the surgical cervical approach. Tumor resection was successful and the calcemia levels promptly returned to normal levels.
    MeSH term(s) Adenoma/complications ; Adenoma/diagnosis ; Adenoma/surgery ; Aged ; Humans ; Hyperparathyroidism, Primary/etiology ; Hyperparathyroidism, Primary/surgery ; Male ; Mediastinal Neoplasms/complications ; Mediastinal Neoplasms/diagnosis ; Mediastinal Neoplasms/surgery ; Parathyroid Neoplasms/complications ; Parathyroid Neoplasms/diagnosis ; Parathyroid Neoplasms/surgery
    Language Portuguese
    Publishing date 2013-10
    Publishing country Portugal
    Document type Case Reports ; English Abstract ; Journal Article
    ISSN 0873-7215
    ISSN 0873-7215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Miocardiopatia de Takotsubo: Na Origem do Choque Cardiogénico.

    Fevereiro, Maria do Carmo / Simões, Maria Inês / Lampreia, Fátima / Marcão, Isabel / Godinho, António / Lopes, Vitor

    Acta medica portuguesa

    2015  Volume 28, Issue 5, Page(s) 670–673

    Abstract: Takotsubo cardiomyopathy, of unknown etiology, is characterized by sudden and transient systolic dysfunction of the mid-apical segments of the left ventricle without significant coronary disease, and full normalization of segmental changes. More common ... ...

    Title translation Takotsubo Cardiomyopathy: Cause of a Cardiogenic Shock.
    Abstract Takotsubo cardiomyopathy, of unknown etiology, is characterized by sudden and transient systolic dysfunction of the mid-apical segments of the left ventricle without significant coronary disease, and full normalization of segmental changes. More common in middle-aged women, it is cause of differential diagnosis with acute coronary syndrome. We present the case of a 59 year old woman admitted to the emergency room with sudden chest pain and dyspnea. At presentation: acute hypotensive pulmonary edema requiring aminergic support and invasive ventilation. Blood tests showed elevated necrosis myocardial enzymes. Serial electrocardiograms: sinus rhythm with progressive inversion of the T wave through the precordial leads (v2 - v6). Control echocardiograms: overall decreased systolic function with apical akinesia, and full reversal of the changes in 2 weeks. Cardiogenic shock of unknown etiology was admitted and a coronary computed tomography angiography was performed excluding coronary heart disease, supporting the diagnosis of Takotsubo cardiomyopathy.
    Language Portuguese
    Publishing date 2015-09
    Publishing country Portugal
    Document type English Abstract ; Journal Article
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
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  6. Article: Oxovanadium(IV) complexes of salicyl-L-aspartic acid and salicylglycyl-L-aspartic acid.

    Jakusch, Tamás / Marcão, Susana / Rodrigues, Lígia / Correia, Isabel / Pessoa, João Costa / Kiss, Tamás

    Dalton transactions (Cambridge, England : 2003)

    2005  , Issue 18, Page(s) 3072–3078

    Abstract: The dipeptide and tripeptide analogues salicyl-L-aspartic acid (Sal-L-Asp) and salicylglycyl-L-aspartic acid (SalGly-L-Asp) were synthesized and their protonation and complex formation with V(IV)O2+ were studied in aqueous solution through the use of pH- ... ...

    Abstract The dipeptide and tripeptide analogues salicyl-L-aspartic acid (Sal-L-Asp) and salicylglycyl-L-aspartic acid (SalGly-L-Asp) were synthesized and their protonation and complex formation with V(IV)O2+ were studied in aqueous solution through the use of pH-potentiometry and spectroscopic (UV-Vis, CD and EPR) techniques. The phenolate terminus proved to be a good anchoring site to promote (i) the metal ion-induced deprotonation and subsequent coordination of the peptide amide group(s) in the pH range 4-5 for the dipeptide analogue, (ii) and in the pH range 5-6 in a very cooperative way for the tripeptide analogue. The results suggest that the presence of good anchoring donors on both sides of the amide groups is responsible for the cooperative deprotonation of the two amide-NH groups.
    MeSH term(s) Aspartic Acid/analogs & derivatives ; Aspartic Acid/chemical synthesis ; Aspartic Acid/chemistry ; Hydrogen-Ion Concentration ; Ligands ; Molecular Structure ; Organometallic Compounds/chemistry ; Stereoisomerism ; Vanadium/chemistry
    Chemical Substances Ligands ; Organometallic Compounds ; Vanadium (00J9J9XKDE) ; Aspartic Acid (30KYC7MIAI)
    Language English
    Publishing date 2005-09-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1472887-4
    ISSN 1364-5447 ; 1477-9234 ; 1477-9226 ; 0300-9246
    ISSN (online) 1364-5447 ; 1477-9234
    ISSN 1477-9226 ; 0300-9246
    DOI 10.1039/b506684k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Echocardiography in emergency.

    Marcão, Isabel / Teixeira, Helena / Longo, Susana / Robalo, Miguel / Oliveira, Susana / Fevereiro, Teresa / Godinho, António / Ramos, Alexandra / Pereira, Trigo

    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

    2004  Volume 23, Issue 1, Page(s) 81–92

    Abstract: The use of echocardiography is still far from optimal. It is difficult or impossible to ensure the 24-hour presence at a hospital of a cardiologist with experience in echocardiography. As a result other specialties are becoming familiar with this ... ...

    Abstract The use of echocardiography is still far from optimal. It is difficult or impossible to ensure the 24-hour presence at a hospital of a cardiologist with experience in echocardiography. As a result other specialties are becoming familiar with this technique. Echocardiography has been recognized as of paramount importance in diagnosis, prognosis and therapeutic decisions in several diseases and therefore echocardiographic training with different levels of experience should be supported and coordinated by a reference group in such matters. The authors review some aspects of echocardiography in emergency. They emphasize the importance of continuous training and accreditation as required conditions to perform echocardiography.
    MeSH term(s) Cardiology Service, Hospital ; Echocardiography ; Emergencies ; Emergency Service, Hospital ; Humans ; Intensive Care Units ; Trauma Centers
    Language Portuguese
    Publishing date 2004-01
    Publishing country Portugal
    Document type Journal Article ; Review
    ZDB-ID 632718-7
    ISSN 0870-2551 ; 0304-4750
    ISSN 0870-2551 ; 0304-4750
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Outcome of three cases of untreated maternal glutaric aciduria type I.

    Garcia, Paula / Martins, Esmeralda / Diogo, Luísa / Rocha, Hugo / Marcão, Ana / Gaspar, Eurico / Almeida, Margarida / Vaz, Catarina / Soares, Isabel / Barbot, Clara / Vilarinho, Laura

    European journal of pediatrics

    2008  Volume 167, Issue 5, Page(s) 569–573

    Abstract: We report, for the first time, the outcome of three children born to two women with untreated glutaric aciduria type I (GA I). Isolated hypocarnitinemia in neonatal screening in one baby allowed the identification of the disease in his mother, who was ... ...

    Abstract We report, for the first time, the outcome of three children born to two women with untreated glutaric aciduria type I (GA I). Isolated hypocarnitinemia in neonatal screening in one baby allowed the identification of the disease in his mother, who was undiagnosed so far and had had a previous daughter. The other baby was born to an already diagnosed mother who was not treated; newborn screening in the child reflected the metabolic state of the mother. Biochemical abnormalities returned to normal within one week. At the age of 4 months, neuroimaging showed Sylvian enlargement in both infants and bilateral temporal arachnoid cysts in one. Physical and neurological developments were normal for the three patients at ages 2 and 5 years. We conclude that long-term follow up will determine the true impact of GA I in such children.
    MeSH term(s) Adult ; Arachnoid Cysts/diagnosis ; Arachnoid Cysts/etiology ; Brain/pathology ; DNA/genetics ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Glutarates/urine ; Glutaryl-CoA Dehydrogenase/genetics ; Humans ; Infant, Newborn ; Magnetic Resonance Imaging ; Male ; Metabolism, Inborn Errors/complications ; Metabolism, Inborn Errors/diagnosis ; Metabolism, Inborn Errors/urine ; Mutation ; Time Factors
    Chemical Substances Glutarates ; DNA (9007-49-2) ; Glutaryl-CoA Dehydrogenase (EC 1.3.8.6) ; glutaric acid (H849F7N00B)
    Language English
    Publishing date 2008-05
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-007-0556-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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