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  1. Article ; Online: Arthur Benton and a bunch of Dutch flowers.

    Bouma, Anke / Bakker, Dirk J

    Journal of clinical and experimental neuropsychology

    2009  Volume 31, Issue 2, Page(s) 154–157

    Abstract: This paper shows how Arthur Benton's excellent research in the field of neuropsychological topics ...

    Abstract This paper shows how Arthur Benton's excellent research in the field of neuropsychological topics like hemispheric specialization, Gerstmann syndrome, aphasia, prosopagnosia and visuospatial deficits has influenced the development of the field of neuropsychology in The Netherlands. Also, his outstanding methodological knowledge and clinical experience have had an enormously significant impact on neuropsychological assessment in this country. Benton's knowledge about the different topics in neuropsychology was tremendous, while at the same time he was always critical and aware of findings he was not able to understand.
    MeSH term(s) Brain/physiology ; Cognition Disorders/history ; Dominance, Cerebral/physiology ; History, 20th Century ; History, 21st Century ; Humans ; Netherlands ; Neuropsychology/history ; Prosopagnosia/history ; United States
    Language English
    Publishing date 2009-02
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 605982-x
    ISSN 1744-411X ; 0168-8634 ; 1380-3395
    ISSN (online) 1744-411X
    ISSN 0168-8634 ; 1380-3395
    DOI 10.1080/13803390802082039
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2393: Show issues Location:
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  2. Article ; Online: Editorial.

    Bakker, Arthur / Wagner, David

    Educational studies in mathematics

    2021  Volume 106, Issue 1, Page(s) 1–3

    Language English
    Publishing date 2021-01-04
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2012239-1
    ISSN 1573-0816 ; 0013-1954
    ISSN (online) 1573-0816
    ISSN 0013-1954
    DOI 10.1007/s10649-020-10015-y
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  3. Article ; Online: Pandemic: lessons for today and tomorrow?

    Bakker, Arthur / Wagner, David

    Educational studies in mathematics

    2020  Volume 104, Issue 1, Page(s) 1–4

    Language English
    Publishing date 2020-03-26
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2012239-1
    ISSN 1573-0816 ; 0013-1954
    ISSN (online) 1573-0816
    ISSN 0013-1954
    DOI 10.1007/s10649-020-09946-3
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  4. Article ; Online: Hypochlorous acid exposure impairs skeletal muscle function and Ca

    Lea, Thomas A / Panizza, Peter M / Arthur, Peter G / Bakker, Anthony J / Pinniger, Gavin J

    The Journal of physiology

    2023  Volume 601, Issue 23, Page(s) 5257–5275

    Abstract: Duchenne muscular dystrophy (DMD) is a fatal X-linked disease characterised by severe muscle wasting. The mechanisms underlying the DMD pathology likely involve the interaction between inflammation, oxidative stress and impaired ... ...

    Abstract Duchenne muscular dystrophy (DMD) is a fatal X-linked disease characterised by severe muscle wasting. The mechanisms underlying the DMD pathology likely involve the interaction between inflammation, oxidative stress and impaired Ca
    MeSH term(s) Animals ; Mice ; Muscular Dystrophy, Duchenne ; Hypochlorous Acid/pharmacology ; Hypochlorous Acid/metabolism ; Hypochlorous Acid/therapeutic use ; Peroxidase/metabolism ; Mice, Inbred mdx ; Mice, Inbred C57BL ; Muscle, Skeletal/metabolism ; Inflammation/metabolism ; Disease Models, Animal
    Chemical Substances Hypochlorous Acid (712K4CDC10) ; Peroxidase (EC 1.11.1.7)
    Language English
    Publishing date 2023-10-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP285263
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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Future themes of mathematics education research: an international survey before and during the pandemic.

    Bakker, Arthur / Cai, Jinfa / Zenger, Linda

    Educational studies in mathematics

    2021  Volume 107, Issue 1, Page(s) 1–24

    Abstract: Before the pandemic (2019), we asked: ...

    Abstract Before the pandemic (2019), we asked:
    Language English
    Publishing date 2021-04-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012239-1
    ISSN 1573-0816 ; 0013-1954
    ISSN (online) 1573-0816
    ISSN 0013-1954
    DOI 10.1007/s10649-021-10049-w
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  6. Article: Follicle-Stimulating Hormone Receptor Expression and Its Potential Application for Theranostics in Subtypes of Ovarian Tumors: A Systematic Review.

    Bakker, Marie-Christine E / Brink, Geertruid J / Poot, Alex J / Braat, Arthur J A T / Jonges, Geertruida N / Zweemer, Ronald P

    Cancers

    2024  Volume 16, Issue 6

    Abstract: Ovarian cancer mortality rates have not decreased significantly in the past years. As most women are still diagnosed in an advanced stage, there is a need for new treatment strategies for recurrent disease. A potentially new developing targeted approach, ...

    Abstract Ovarian cancer mortality rates have not decreased significantly in the past years. As most women are still diagnosed in an advanced stage, there is a need for new treatment strategies for recurrent disease. A potentially new developing targeted approach, theranostics, combines diagnostics and treatment using radiopharmaceuticals. Through target receptors, imaging and treatment of malignant tissue can be achieved. For ovarian malignancy, the follicle-stimulating hormone (FSH) receptor may serve as a possible target since expression appears to be limited to ovarian cells. In this systematic review, we aim to gather all available literature on the expression of the FSH receptor in ovarian tumors. Pubmed, Embase and the Cochrane databases were searched until December 2023 for eligible studies. The search yielded 41 studies, mostly regarding serous carcinomas, sex cord-stromal tumors (SCSTs) and cell lines of serous and SCSTs. Various techniques were used to analyze the expression of the FSH receptor. For serous carcinomas, conflicting results on the expression of the FSH receptor were found. Studies on SCSTs, mainly studying the subtype of granulosa cell tumors, all showed positive expression of the FSH receptor. In the cell lines studies, the KGN cell line derived from a granulosa cell tumor shows positive expression in all studies. Available studies show that SCSTs express the FSH receptor. A theranostic approach targeting the FSH receptor may, therefore, provide a useful new approach for this malignancy with limited therapeutic options in recurrent disease.
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16061140
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  7. Article: Academic discourse on education during the early part of the pandemic.

    Meulenbroeks, Ralph / Reijerkerk, Martijn / Angerer, Elisabeth / Pieters, Toine / Bakker, Arthur

    Heliyon

    2022  Volume 8, Issue 10, Page(s) e11170

    Abstract: As the global COVID-19 pandemic forced a sudden transition to emergency online education in early 2020, academic discourse quickly shifted to focus on the new situation and what could be learned from it. The present study gives an overview of the ... ...

    Abstract As the global COVID-19 pandemic forced a sudden transition to emergency online education in early 2020, academic discourse quickly shifted to focus on the new situation and what could be learned from it. The present study gives an overview of the discourse on education during the pandemic in publications that appeared in the top-50 journals on the Clarivate Education list in the period April 2020-May 2021. Based on a final selection of 63 articles and 12 editorials, mostly on higher education, five main themes were identified: affect, teaching practice, teaching context, achievement and assessment, and equity. The academic discourse in these publications indicates that the emergency situation exacerbated previously existing issues: mental distress was observed to rise sharply for all stakeholders and gaps in access to education between different social groups widened. In response, teachers revisited the core values of education to guide them in approaching online teaching. Management focused less on procedures and communicated in a more human and empathic way. We argue that the acute interconnectedness experienced during the pandemic can be used to develop a pedagogy of care in which support is explicitly organized on both socio-emotional and academic levels.
    Language English
    Publishing date 2022-10-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11170
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  9. Article ; Online: Abstracts from the 2022 European Association for Vision and Eye Research Festival, 13-15 October 2022, Valencia.

    Wagstaff, Ellie / Bakker, Reinier / Emri, Eszter / Ten Asbroek, Anneloor / Bergen, Arthur

    Acta ophthalmologica

    2023  Volume 100 Suppl 275

    Abstract: Purpose: Albinism refers to a group of genetic disorders typically characterized by a loss/reduction of melanin in the hair, skin and eyes of affected patients. Apart from pigment changes, all albinism patients present with foveal hypoplasia and optic ... ...

    Abstract Purpose: Albinism refers to a group of genetic disorders typically characterized by a loss/reduction of melanin in the hair, skin and eyes of affected patients. Apart from pigment changes, all albinism patients present with foveal hypoplasia and optic nerve misrouting, and have blurred vision. The molecular mechanisms that link this lack of pigment with neural retinal development are poorly understood, with foveal and optic tract development being difficult to model. To advance our knowledge, we developed a novel retinal organoid model of albinism, and characterized the development and outgrowth of retinal ganglion cells affected during albinism as a model for future studies.
    Methods: Human oculocutaneous albinism 1 (OCA1) patient-derived stem cells were differentiated alongside controls into retinal organoids, as published previously
    Results: IHC analysis showed differences in the number of ipsilateral and contralateral retinal ganglion cells between the healthy control and albinism organoids, in line with in vivo observations. Further, optic nerve-like outgrowth could be achieved with both models, allowing for future research into optic nerve misrouting in albinism.
    Conclusions: We generated a novel retinal organoid model of oculocutaneous albinism, and characterized the retinal ganglion cell development and outgrowth. This will allow us in the future to study a different and sometimes overlooked aspect of albinism; optic nerve misrouting. References 1. Wagstaff, P. E., Ten Asbroek, A., Ten Brink, J. B., Jansonius, N. M. & Bergen, A. A. B. An alternative approach to produce versatile retinal organoids with accelerated ganglion cell development. Sci Rep 11, 1101, doi:10.1038/s41598-020-79651-x (2021). 2. Ohlemacher, S. K. et al. Stepwise Differentiation of Retinal Ganglion Cells from Human Pluripotent Stem Cells Enables Analysis of Glaucomatous Neurodegeneration. Stem Cells 34, 1553-1562, doi:10.1002/stem.2356 (2016).
    Language English
    Publishing date 2023-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/j.1755-3768.2022.0616
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    In stock of ZB MED Cologne/Königswinter

    Ul I Zs.90: Show issues Location:
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  10. Article ; Online: Academic discourse on education during the early part of the pandemic

    Ralph Meulenbroeks / Martijn Reijerkerk / Elisabeth Angerer / Toine Pieters / Arthur Bakker

    Heliyon, Vol 8, Iss 10, Pp e11170- (2022)

    2022  

    Abstract: As the global COVID-19 pandemic forced a sudden transition to emergency online education in early 2020, academic discourse quickly shifted to focus on the new situation and what could be learned from it. The present study gives an overview of the ... ...

    Abstract As the global COVID-19 pandemic forced a sudden transition to emergency online education in early 2020, academic discourse quickly shifted to focus on the new situation and what could be learned from it. The present study gives an overview of the discourse on education during the pandemic in publications that appeared in the top-50 journals on the Clarivate Education list in the period April 2020–May 2021. Based on a final selection of 63 articles and 12 editorials, mostly on higher education, five main themes were identified: affect, teaching practice, teaching context, achievement and assessment, and equity. The academic discourse in these publications indicates that the emergency situation exacerbated previously existing issues: mental distress was observed to rise sharply for all stakeholders and gaps in access to education between different social groups widened. In response, teachers revisited the core values of education to guide them in approaching online teaching. Management focused less on procedures and communicated in a more human and empathic way. We argue that the acute interconnectedness experienced during the pandemic can be used to develop a pedagogy of care in which support is explicitly organized on both socio-emotional and academic levels.
    Keywords Higher education ; Pandemic ; COVID-19 ; Pedagogy of care ; Online education ; Blended learning ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 028 ; 370
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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