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Article ; Online: GW190521: A Binary Black Hole Merger with a Total Mass of 150 M_{⊙}.

Abbott, R / Abbott, T D / Abraham, S / Acernese, F / Ackley, K / Adams, C / Adhikari, R X / Adya, V B / Affeldt, C / Agathos, M / Agatsuma, K / Aggarwal, N / Aguiar, O D / Aich, A / Aiello, L / Ain, A / Ajith, P / Akcay, S / Allen, G /

Allocca, A / Altin, P A / Amato, A / Anand, S / Ananyeva, A / Anderson, S B / Anderson, W G / Angelova, S V / Ansoldi, S / Antier, S / Appert, S / Arai, K / Araya, M C / Areeda, J S / Arène, M / Arnaud, N / Aronson, S M / Arun, K G / Asali, Y / Ascenzi, S / Ashton, G / Aston, S M / Astone, P / Aubin, F / Aufmuth, P / AultONeal, K / Austin, C / Avendano, V / Babak, S / Bacon, P / Badaracco, F / Bader, M K M / Bae, S / Baer, A M / Baird, J / Baldaccini, F / Ballardin, G / Ballmer, S W / Bals, A / Balsamo, A / Baltus, G / Banagiri, S / Bankar, D / Bankar, R S / Barayoga, J C / Barbieri, C / Barish, B C / Barker, D / Barkett, K / Barneo, P / Barone, F / Barr, B / Barsotti, L / Barsuglia, M / Barta, D / Bartlett, J / Bartos, I / Bassiri, R / Basti, A / Bawaj, M / Bayley, J C / Bazzan, M / Bécsy, B / Bejger, M / Belahcene, I / Bell, A S / Beniwal, D / Benjamin, M G / Bentley, J D / Bergamin, F / Berger, B K / Bergmann, G / Bernuzzi, S / Berry, C P L / Bersanetti, D / Bertolini, A / Betzwieser, J / Bhandare, R / Bhandari, A V / Bidler, J / Biggs, E / Bilenko, I A / Billingsley, G / Birney, R / Birnholtz, O / Biscans, S / Bischi, M / Biscoveanu, S / Bisht, A / Bissenbayeva, G / Bitossi, M / Bizouard, M A / Blackburn, J K / Blackman, J / Blair, C D / Blair, D G / Blair, R M / Bobba, F / Bode, N / Boer, M / Boetzel, Y / Bogaert, G / Bondu, F / Bonilla, E / Bonnand, R / Booker, P / Boom, B A / Bork, R / Boschi, V / Bose, S / Bossilkov, V / Bosveld, J / Bouffanais, Y / Bozzi, A / Bradaschia, C / Brady, P R / Bramley, A / Branchesi, M / Brau, J E / Breschi, M / Briant, T / Briggs, J H / Brighenti, F / Brillet, A / Brinkmann, M / Brockill, P / Brooks, A F / Brooks, J / Brown, D D / Brunett, S / Bruno, G / Bruntz, R / Buikema, A / Bulik, T / Bulten, H J / Buonanno, A / Buscicchio, R / Buskulic, D / Byer, R L / Cabero, M / Cadonati, L / Cagnoli, G / Cahillane, C / Calderón Bustillo, J / Callaghan, J D / Callister, T A / Calloni, E / Camp, J B / Canepa, M / Cannon, K C / Cao, H / Cao, J / Carapella, G / Carbognani, F / Caride, S / Carney, M F / Carullo, G / Casanueva Diaz, J / Casentini, C / Castañeda, J / Caudill, S / Cavaglià, M / Cavalier, F / Cavalieri, R / Cella, G / Cerdá-Durán, P / Cesarini, E / Chaibi, O / Chakravarti, K / Chan, C / Chan, M / Chandra, K / Chao, S / Charlton, P / Chase, E A / Chassande-Mottin, E / Chatterjee, D / Chaturvedi, M / Chatziioannou, K / Chen, H Y / Chen, X / Chen, Y / Cheng, H-P / Cheong, C K / Chia, H Y / Chiadini, F / Chierici, R / Chincarini, A / Chiummo, A / Cho, G / Cho, H S / Cho, M / Christensen, N / Chu, Q / Chua, S / Chung, K W / Chung, S / Ciani, G / Ciecielag, P / Cieślar, M / Ciobanu, A A / Ciolfi, R / Cipriano, F / Cirone, A / Clara, F / Clark, J A / Clearwater, P / Clesse, S / Cleva, F / Coccia, E / Cohadon, P-F / Cohen, D / Colleoni, M / Collette, C G / Collins, C / Colpi, M / Constancio, M / Conti, L / Cooper, S J / Corban, P / Corbitt, T R / Cordero-Carrión, I / Corezzi, S / Corley, K R / Cornish, N / Corre, D / Corsi, A / Cortese, S / Costa, C A / Cotesta, R / Coughlin, M W / Coughlin, S B / Coulon, J-P / Countryman, S T / Couvares, P / Covas, P B / Coward, D M / Cowart, M J / Coyne, D C / Coyne, R / Creighton, J D E / Creighton, T D / Cripe, J / Croquette, M / Crowder, S G / Cudell, J-R / Cullen, T J / Cumming, A / Cummings, R / Cunningham, L / Cuoco, E / Curylo, M / Canton, T Dal / Dálya, G / Dana, A / Daneshgaran-Bajastani, L M / D'Angelo, B / Danilishin, S L / D'Antonio, S / Danzmann, K / Darsow-Fromm, C / Dasgupta, A / Datrier, L E H / Dattilo, V / Dave, I / Davier, M / Davies, G S / Davis, D / Daw, E J / DeBra, D / Deenadayalan, M / Degallaix, J / De Laurentis, M / Deléglise, S / Delfavero, M / De Lillo, N / Del Pozzo, W / DeMarchi, L M / D'Emilio, V / Demos, N / Dent, T / De Pietri, R / De Rosa, R / De Rossi, C / DeSalvo, R / de Varona, O / Dhurandhar, S / Díaz, M C / Diaz-Ortiz, M / Dietrich, T / Di Fiore, L / Di Fronzo, C / Di Giorgio, C / Di Giovanni, F / Di Giovanni, M / Di Girolamo, T / Di Lieto, A / Ding, B / Di Pace, S / Di Palma, I / Di Renzo, F / Divakarla, A K / Dmitriev, A / Doctor, Z / Donovan, F / Dooley, K L / Doravari, S / Dorrington, I / Downes, T P / Drago, M / Driggers, J C / Du, Z / Ducoin, J-G / Dupej, P / Durante, O / D'Urso, D / Dwyer, S E / Easter, P J / Eddolls, G / Edelman, B / Edo, T B / Edy, O / Effler, A / Ehrens, P / Eichholz, J / Eikenberry, S S / Eisenmann, M / Eisenstein, R A / Ejlli, A / Errico, L / Essick, R C / Estelles, H / Estevez, D / Etienne, Z B / Etzel, T / Evans, M / Evans, T M / Ewing, B E / Fafone, V / Fairhurst, S / Fan, X / Farinon, S / Farr, B / Farr, W M / Fauchon-Jones, E J / Favata, M / Fays, M / Fazio, M / Feicht, J / Fejer, M M / Feng, F / Fenyvesi, E / Ferguson, D L / Fernandez-Galiana, A / Ferrante, I / Ferreira, E C / Ferreira, T A / Fidecaro, F / Fiori, I / Fiorucci, D / Fishbach, M / Fisher, R P / Fittipaldi, R / Fitz-Axen, M / Fiumara, V / Flaminio, R / Floden, E / Flynn, E / Fong, H / Font, J A / Forsyth, P W F / Fournier, J-D / Frasca, S / Frasconi, F / Frei, Z / Freise, A / Frey, R / Frey, V / Fritschel, P / Frolov, V V / Fronzè, G / Fulda, P / Fyffe, M / Gabbard, H A / Gadre, B U / Gaebel, S M / Gair, J R / Galaudage, S / Ganapathy, D / Ganguly, A / Gaonkar, S G / García-Quirós, C / Garufi, F / Gateley, B / Gaudio, S / Gayathri, V / Gemme, G / Genin, E / Gennai, A / George, D / George, J / Gergely, L / Ghonge, S / Ghosh, Abhirup / Ghosh, Archisman / Ghosh, S / Giacomazzo, B / Giaime, J A / Giardina, K D / Gibson, D R / Gier, C / Gill, K / Glanzer, J / Gniesmer, J / Godwin, P / Goetz, E / Goetz, R / Gohlke, N / Goncharov, B / González, G / Gopakumar, A / Gossan, S E / Gosselin, M / Gouaty, R / Grace, B / Grado, A / Granata, M / Grant, A / Gras, S / Grassia, P / Gray, C / Gray, R / Greco, G / Green, A C / Green, R / Gretarsson, E M / Griggs, H L / Grignani, G / Grimaldi, A / Grimm, S J / Grote, H / Grunewald, S / Gruning, P / Guidi, G M / Guimaraes, A R / Guixé, G / Gulati, H K / Guo, Y / Gupta, A / Gupta, Anchal / Gupta, P / Gustafson, E K / Gustafson, R / Haegel, L / Halim, O / Hall, E D / Hamilton, E Z / Hammond, G / Haney, M / Hanke, M M / Hanks, J / Hanna, C / Hannam, M D / Hannuksela, O A / Hansen, T J / Hanson, J / Harder, T / Hardwick, T / Haris, K / Harms, J / Harry, G M / Harry, I W / Hasskew, R K / Haster, C-J / Haughian, K / Hayes, F J / Healy, J / Heidmann, A / Heintze, M C / Heinze, J / Heitmann, H / Hellman, F / Hello, P / Hemming, G / Hendry, M / Heng, I S / Hennes, E / Hennig, J / Heurs, M / Hild, S / Hinderer, T / Hoback, S Y / Hochheim, S / Hofgard, E / Hofman, D / Holgado, A M / Holland, N A / Holt, K / Holz, D E / Hopkins, P / Horst, C / Hough, J / Howell, E J / Hoy, C G / Huang, Y / Hübner, M T / Huerta, E A / Huet, D / Hughey, B / Hui, V / Husa, S / Huttner, S H / Huxford, R / Huynh-Dinh, T / Idzkowski, B / Iess, A / Inchauspe, H / Ingram, C / Intini, G / Isac, J-M / Isi, M / Iyer, B R / Jacqmin, T / Jadhav, S J / Jadhav, S P / James, A L / Jani, K / Janthalur, N N / Jaranowski, P / Jariwala, D / Jaume, R / Jenkins, A C / Jiang, J / Johns, G R / Johnson-McDaniel, N K / Jones, A W / Jones, D I / Jones, J D / Jones, P / Jones, R / Jonker, R J G / Ju, L / Junker, J / Kalaghatgi, C V / Kalogera, V / Kamai, B / Kandhasamy, S / Kang, G / Kanner, J B / Kapadia, S J / Karki, S / Kashyap, R / Kasprzack, M / Kastaun, W / Katsanevas, S / Katsavounidis, E / Katzman, W / Kaufer, S / Kawabe, K / Kéfélian, F / Keitel, D / Keivani, A / Kennedy, R / Key, J S / Khadka, S / Khalili, F Y / Khan, I / Khan, S / Khan, Z A / Khazanov, E A / Khetan, N / Khursheed, M / Kijbunchoo, N / Kim, Chunglee / Kim, G J / Kim, J C / Kim, K / Kim, W / Kim, W S / Kim, Y-M / Kimball, C / King, P J / Kinley-Hanlon, M / Kirchhoff, R / Kissel, J S / Kleybolte, L / Klimenko, S / Knowles, T D / Knyazev, E / Koch, P / Koehlenbeck, S M / Koekoek, G / Koley, S / Kondrashov, V / Kontos, A / Koper, N / Korobko, M / Korth, W Z / Kovalam, M / Kozak, D B / Kringel, V / Krishnendu, N V / Królak, A / Krupinski, N / Kuehn, G / Kumar, A / Kumar, P / Kumar, Rahul / Kumar, Rakesh / Kumar, S / Kuo, L / Kutynia, A / Lackey, B D / Laghi, D / Lalande, E / Lam, T L / Lamberts, A / Landry, M / Lane, B B / Lang, R N / Lange, J / Lantz, B / Lanza, R K / La Rosa, I / Lartaux-Vollard, A / Lasky, P D / Laxen, M / Lazzarini, A / Lazzaro, C / Leaci, P / Leavey, S / Lecoeuche, Y K / Lee, C H / Lee, H M / Lee, H W / Lee, J / Lee, K / Lehmann, J / Leroy, N / Letendre, N / Levin, Y / Li, A K Y / Li, J / Li, K / Li, T G F / Li, X / Linde, F / Linker, S D / Linley, J N / Littenberg, T B / Liu, J / Liu, X / Llorens-Monteagudo, M / Lo, R K L / Lockwood, A / London, L T / Longo, A / Lorenzini, M / Loriette, V / Lormand, M / Losurdo, G / Lough, J D / Lousto, C O / Lovelace, G / Lück, H / Lumaca, D / Lundgren, A P / Ma, Y / Macas, R / Macfoy, S / MacInnis, M / Macleod, D M / MacMillan, I A O / Macquet, A / Magaña Hernandez, I / Magaña-Sandoval, F / Magee, R M / Majorana, E / Maksimovic, I / Malik, A / Man, N / Mandic, V / Mangano, V / Mansell, G L / Manske, M / Mantovani, M / Mapelli, M / Marchesoni, F / Marion, F / Márka, S / Márka, Z / Markakis, C / Markosyan, A S / Markowitz, A / Maros, E / Marquina, A / Marsat, S / Martelli, F / Martin, I W / Martin, R M / Martinez, V / Martynov, D V / Masalehdan, H / Mason, K / Massera, E / Masserot, A / Massinger, T J / Masso-Reid, M / Mastrogiovanni, S / Matas, A / Matichard, F / Mavalvala, N / Maynard, E / McCann, J J / McCarthy, R / McClelland, D E / McCormick, S / McCuller, L / McGuire, S C / McIsaac, C / McIver, J / McManus, D J / McRae, T / McWilliams, S T / Meacher, D / Meadors, G D / Mehmet, M / Mehta, A K / Mejuto Villa, E / Melatos, A / Mendell, G / Mercer, R A / Mereni, L / Merfeld, K / Merilh, E L / Merritt, J D / Merzougui, M / Meshkov, S / Messenger, C / Messick, C / Metzdorff, R / Meyers, P M / Meylahn, F / Mhaske, A / Miani, A / Miao, H / Michaloliakos, I / Michel, C / Middleton, H / Milano, L / Miller, A L / Millhouse, M / Mills, J C / Milotti, E / Milovich-Goff, M C / Minazzoli, O / Minenkov, Y / Mishkin, A / Mishra, C / Mistry, T / Mitra, S / Mitrofanov, V P / Mitselmakher, G / Mittleman, R / Mo, G / Mogushi, K / Mohapatra, S R P / Mohite, S R / Molina-Ruiz, M / Mondin, M / Montani, M / Moore, C J / Moraru, D / Morawski, F / Moreno, G / Morisaki, S / Mours, B / Mow-Lowry, C M / Mozzon, S / Muciaccia, F / Mukherjee, Arunava / Mukherjee, D / Mukherjee, S / Mukherjee, Subroto / Mukund, N / Mullavey, A / Munch, J / Muñiz, E A / Murray, P G / Nagar, A / Nardecchia, I / Naticchioni, L / Nayak, R K / Neil, B F / Neilson, J / Nelemans, G / Nelson, T J N / Nery, M / Neunzert, A / Ng, K Y / Ng, S / Nguyen, C / Nguyen, P / Nichols, D / Nichols, S A / Nissanke, S / Nitz, A / Nocera, F / Noh, M / North, C / Nothard, D / Nuttall, L K / Oberling, J / O'Brien, B D / Oganesyan, G / Ogin, G H / Oh, J J / Oh, S H / Ohme, F / Ohta, H / Okada, M A / Oliver, M / Olivetto, C / Oppermann, P / Oram, Richard J / O'Reilly, B / Ormiston, R G / Ortega, L F / O'Shaughnessy, R / Ossokine, S / Osthelder, C / Ottaway, D J / Overmier, H / Owen, B J / Pace, A E / Pagano, G / Page, M A / Pagliaroli, G / Pai, A / Pai, S A / Palamos, J R / Palashov, O / Palomba, C / Pan, H / Panda, P K / Pang, P T H / Pankow, C / Pannarale, F / Pant, B C / Paoletti, F / Paoli, A / Parida, A / Parker, W / Pascucci, D / Pasqualetti, A / Passaquieti, R / Passuello, D / Patricelli, B / Payne, E / Pearlstone, B L / Pechsiri, T C / Pedersen, A J / Pedraza, M / Pele, A / Penn, S / Perego, A / Perez, C J / Périgois, C / Perreca, A / Perriès, S / Petermann, J / Pfeiffer, H P / Phelps, M / Phukon, K S / Piccinni, O J / Pichot, M / Piendibene, M / Piergiovanni, F / Pierro, V / Pillant, G / Pinard, L / Pinto, I M / Piotrzkowski, K / Pirello, M / Pitkin, M / Plastino, W / Poggiani, R / Pong, D Y T / Ponrathnam, S / Popolizio, P / Porter, E K / Powell, J / Prajapati, A K / Prasai, K / Prasanna, R / Pratten, G / Prestegard, T / Principe, M / Prodi, G A / Prokhorov, L / Punturo, M / Puppo, P / Pürrer, M / Qi, H / Quetschke, V / Quinonez, P J / Raab, F J / Raaijmakers, G / Radkins, H / Radulesco, N / Raffai, P / Rafferty, H / Raja, S / Rajan, C / Rajbhandari, B / Rakhmanov, M / Ramirez, K E / Ramos-Buades, A / Rana, Javed / Rao, K / Rapagnani, P / Raymond, V / Razzano, M / Read, J / Regimbau, T / Rei, L / Reid, S / Reitze, D H / Rettegno, P / Ricci, F / Richardson, C J / Richardson, J W / Ricker, P M / Riemenschneider, G / Riles, K / Rizzo, M / Robertson, N A / Robinet, F / Rocchi, A / Rodriguez-Soto, R D / Rolland, L / Rollins, J G / Roma, V J / Romanelli, M / Romano, R / Romel, C L / Romero-Shaw, I M / Romie, J H / Rose, C A / Rose, D / Rose, K / Rosińska, D / Rosofsky, S G / Ross, M P / Rowan, S / Rowlinson, S J / Roy, P K / Roy, Santosh / Roy, Soumen / Ruggi, P / Rutins, G / Ryan, K / Sachdev, S / Sadecki, T / Sakellariadou, M / Salafia, O S / Salconi, L / Saleem, M / Salemi, F / Samajdar, A / Sanchez, E J / Sanchez, L E / Sanchis-Gual, N / Sanders, J R / Santiago, K A / Santos, E / Sarin, N / Sassolas, B / Sathyaprakash, B S / Sauter, O / Savage, R L / Savant, V / Sawant, D / Sayah, S / Schaetzl, D / Schale, P / Scheel, M / Scheuer, J / Schmidt, P / Schnabel, R / Schofield, R M S / Schönbeck, A / Schreiber, E / Schulte, B W / Schutz, B F / Schwarm, O / Schwartz, E / Scott, J / Scott, S M / Seidel, E / Sellers, D / Sengupta, A S / Sennett, N / Sentenac, D / Sequino, V / Sergeev, A / Setyawati, Y / Shaddock, D A / Shaffer, T / Sharifi, S / Shahriar, M S / Sharma, A / Sharma, P / Shawhan, P / Shen, H / Shikauchi, M / Shink, R / Shoemaker, D H / Shoemaker, D M / Shukla, K / ShyamSundar, S / Siellez, K / Sieniawska, M / Sigg, D / Singer, L P / Singh, D / Singh, N / Singha, A / Singhal, A / Sintes, A M / Sipala, V / Skliris, V / Slagmolen, B J J / Slaven-Blair, T J / Smetana, J / Smith, J R / Smith, R J E / Somala, S / Son, E J / Soni, S / Sorazu, B / Sordini, V / Sorrentino, F / Souradeep, T / Sowell, E / Spencer, A P / Spera, M / Srivastava, A K / Srivastava, V / Staats, K / Stachie, C / Standke, M / Steer, D A / Steinke, M / Steinlechner, J / Steinlechner, S / Steinmeyer, D / Stevenson, S / Stocks, D / Stops, D J / Stover, M / Strain, K A / Stratta, G / Strunk, A / Sturani, R / Stuver, A L / Sudhagar, S / Sudhir, V / Summerscales, T Z / Sun, L / Sunil, S / Sur, A / Suresh, J / Sutton, P J / Swinkels, B L / Szczepańczyk, M J / Tacca, M / Tait, S C / Talbot, C / Tanasijczuk, A J / Tanner, D B / Tao, D / Tápai, M / Tapia, A / Tapia San Martin, E N / Tasson, J D / Taylor, R / Tenorio, R / Terkowski, L / Thirugnanasambandam, M P / Thomas, M / Thomas, P / Thompson, J E / Thondapu, S R / Thorne, K A / Thrane, E / Tinsman, C L / Saravanan, T R / Tiwari, Shubhanshu / Tiwari, S / Tiwari, V / Toland, K / Tonelli, M / Tornasi, Z / Torres-Forné, A / Torrie, C I / Tosta E Melo, I / Töyrä, D / Travasso, F / Traylor, G / Tringali, M C / Tripathee, A / Trovato, A / Trudeau, R J / Tsang, K W / Tse, M / Tso, R / Tsukada, L / Tsuna, D / Tsutsui, T / Turconi, M / Ubhi, A S / Udall, R / Ueno, K / Ugolini, D / Unnikrishnan, C S / Urban, A L / Usman, S A / Utina, A C / Vahlbruch, H / Vajente, G / Valdes, G / Valentini, M / van Bakel, N / van Beuzekom, M / van den Brand, J F J / Van Den Broeck, C / Vander-Hyde, D C / van der Schaaf, L / Van Heijningen, J V / van Veggel, A A / Vardaro, M / Varma, V / Vass, S / Vasúth, M / Vecchio, A / Vedovato, G / Veitch, J / Veitch, P J / Venkateswara, K / Venugopalan, G / Verkindt, D / Veske, D / Vetrano, F / Viceré, A / Viets, A D / Vinciguerra, S / Vine, D J / Vinet, J-Y / Vitale, S / Vivanco, Francisco Hernandez / Vo, T / Vocca, H / Vorvick, C / Vyatchanin, S P / Wade, A R / Wade, L E / Wade, M / Walet, R / Walker, M / Wallace, G S / Wallace, L / Walsh, S / Wang, J Z / Wang, S / Wang, W H / Ward, R L / Warden, Z A / Warner, J / Was, M / Watchi, J / Weaver, B / Wei, L-W / Weinert, M / Weinstein, A J / Weiss, R / Wellmann, F / Wen, L / Weßels, P / Westhouse, J W / Wette, K / Whelan, J T / Whiting, B F / Whittle, C / Wilken, D M / Williams, D / Willis, J L / Willke, B / Winkler, W / Wipf, C C / Wittel, H / Woan, G / Woehler, J / Wofford, J K / Wong, I C F / Wright, J L / Wu, D S / Wysocki, D M / Xiao, L / Yamamoto, H / Yang, L / Yang, Y / Yang, Z / Yap, M J / Yazback, M / Yeeles, D W / Yu, Hang / Yu, Haocun / Yuen, S H R / Zadrożny, A K / Zadrożny, A / Zanolin, M / Zelenova, T / Zendri, J-P / Zevin, M / Zhang, J / Zhang, L / Zhang, T / Zhao, C / Zhao, G / Zhou, M / Zhou, Z / Zhu, X J / Zimmerman, A B / Zucker, M E / Zweizig, J

Physical review letters

2021 Volume 125, Issue 10, Page(s) 101102

Abstract: ... with masses of 85_{-14}^{+21} M_{⊙} and 66_{-18}^{+17} M_{⊙} (90% credible intervals). We infer ... with only a 0.32% probability of being below 65 M_{⊙}. We calculate the mass of the remnant to be 142_{-16 ... 28} M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance ...

Abstract	On May 21, 2019 at 03:02:29 UTC Advanced LIGO and Advanced Virgo observed a short duration gravitational-wave signal, GW190521, with a three-detector network signal-to-noise ratio of 14.7, and an estimated false-alarm rate of 1 in 4900 yr using a search sensitive to generic transients. If GW190521 is from a quasicircular binary inspiral, then the detected signal is consistent with the merger of two black holes with masses of 85_{-14}^{+21} M_{⊙} and 66_{-18}^{+17} M_{⊙} (90% credible intervals). We infer that the primary black hole mass lies within the gap produced by (pulsational) pair-instability supernova processes, with only a 0.32% probability of being below 65 M_{⊙}. We calculate the mass of the remnant to be 142_{-16}^{+28} M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance of the source is 5.3_{-2.6}^{+2.4} Gpc, corresponding to a redshift of 0.82_{-0.34}^{+0.28}. The inferred rate of mergers similar to GW190521 is 0.13_{-0.11}^{+0.30} Gpc^{-3} yr^{-1}.
Language	English
Publishing date	2021-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.125.101102
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Article: Alcohol as a Dressing for Wounds, with Special Reference to Its Employment by M. Nèlaton, at the Clinical Hospital, Paris, France.

Bradley, W Lockwood

Atlanta medical and surgical journal

2022 Volume 7B, Issue 9, Page(s) 419–424

Language	English
Publishing date	2022-07-11
Publishing country	United States
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Article ; Online: GW190814: Gravitational Waves from the Coalescence of a 23 M$_\odot$ Black Hole with a 2.6 M$_\odot$ Compact Object

Collaboration, The LIGO Scientific / Abbott, the Virgo Collaboration R. / Abbott, T. D. / Abraham, S. / Acernese, F. / Ackley, K. / Adams, C. / Adhikari, R. X. / Adya, V. B. / Affeldt, C. / Agathos, M. / Agatsuma, K. / Aggarwal, N. / Aguiar, O. D. / Aich, A. / Aiello, L. / Ain, A. / Ajith, P. / Akcay, S. /

Allen, G. / Allocca, A. / Altin, P. A. / Amato, A. / Anand, S. / Ananyeva, A. / Anderson, S. B. / Anderson, W. G. / Angelova, S. V. / Ansoldi, S. / Antier, S. / Appert, S. / Arai, K. / Araya, M. C. / Areeda, J. S. / Arene, M. / Arnaud, N. / Aronson, S. M. / Arun, K. G. / Asali, Y. / Ascenzi, S. / Ashton, G. / Aston, S. M. / Astone, P. / Aubin, F. / Aufmuth, P. / AultONeal, K. / Austin, C. / Avendano, V. / Babak, S. / Bacon, P. / Badaracco, F. / Bader, M. K. M. / Bae, S. / Baer, A. M. / Baird, J. / Baldaccini, F. / Ballardin, G. / Ballmer, S. W. / Bals, A. / Balsamo, A. / Baltus, G. / Banagiri, S. / Bankar, D. / Bankar, R. S. / Barayoga, J. C. / Barbieri, C. / Barish, B. C. / Barker, D. / Barkett, K. / Barneo, P. / Barone, F. / Barr, B. / Barsotti, L. / Barsuglia, M. / Barta, D. / Bartlett, J. / Bartos, I. / Bassiri, R. / Basti, A. / Bawaj, M. / Bayley, J. C. / Bazzan, M. / B'ecsy, B. / Bejger, M. / Belahcene, I. / Bell, A. S. / Beniwal, D. / Benjamin, M. G. / Benkel, R. / Bentley, J. D. / Bergamin, F. / Berger, B. K. / Bergmann, G. / Bernuzzi, S. / Berry, C. P. L. / Bersanetti, D. / Bertolini, A. / Betzwieser, J. / Bhandare, R. / Bhandari, A. V. / Bidler, J. / Biggs, E. / Bilenko, I. A. / Billingsley, G. / Birney, R. / Birnholtz, O. / Biscans, S. / Bischi, M. / Biscoveanu, S. / Bisht, A. / Bissenbayeva, G. / Bitossi, M. / Bizouard, M. A. / Blackburn, J. K. / Blackman, J. / Blair, C. D. / Blair, D. G. / Blair, R. M. / Bobba, F. / Bode, N. / Boer, M. / Boetzel, Y. / Bogaert, G. / Bondu, F. / Bonilla, E. / Bonnand, R. / Booker, P. / Boom, B. A. / Bork, R. / Boschi, V. / Bose, S. / Bossilkov, V. / Bosveld, J. / Bouffanais, Y. / Bozzi, A. / Bradaschia, C. / Brady, P. R. / Bramley, A. / Branchesi, M. / Brau, J. E. / Breschi, M. / Briant, T. / Briggs, J. H. / Brighenti, F. / Brillet, A. / Brinkmann, M. / Brito, R. / Brockill, P. / Brooks, A. F. / Brooks, J. / Brown, D. D. / Brunett, S. / Bruno, G. / Bruntz, R. / Buikema, A. / Bulik, T. / Bulten, H. J. / Buonanno, A. / Buskulic, D. / Byer, R. L. / Cabero, M. / Cadonati, L. / Cagnoli, G. / Cahillane, C. / Bustillo, J. Calder'on / Callaghan, J. D. / Callister, T. A. / Calloni, E. / Camp, J. B. / Canepa, M. / Cannon, K. C. / Cao, H. / Cao, J. / Carapella, G. / Carbognani, F. / Caride, S. / Carney, M. F. / Carullo, G. / Diaz, J. Casanueva / Casentini, C. / Castaneda, J. / Caudill, S. / Cavaglia, M. / Cavalier, F. / Cavalieri, R. / Cella, G. / Cerd'a-Dur'an, P. / Cesarini, E. / Chaibi, O. / Chakravarti, K. / Chan, C. / Chan, M. / Chao, S. / Charlton, P. / Chase, E. A. / Chassande-Mottin, E. / Chatterjee, D. / Chaturvedi, M. / Chatziioannou, K. / Chen, H. Y. / Chen, X. / Chen, Y. / Cheng, H.-P. / Cheong, C. K. / Chia, H. Y. / Chiadini, F. / Chierici, R. / Chincarini, A. / Chiummo, A. / Cho, G. / Cho, H. S. / Cho, M. / Christensen, N. / Chu, Q. / Chua, S. / Chung, K. W. / Chung, S. / Ciani, G. / Ciecielag, P. / Cie'slar, M. / Ciobanu, A. A. / Ciolfi, R. / Cipriano, F. / Cirone, A. / Clara, F. / Clark, J. A. / Clearwater, P. / Clesse, S. / Cleva, F. / Coccia, E. / Cohadon, P.-F. / Cohen, D. / Colleoni, M. / Collette, C. G. / Collins, C. / Colpi, M. / Constancio, M. / Conti, L. / Cooper, S. J. / Corban, P. / Corbitt, T. R. / Cordero-Carri'on, I. / Corezzi, S. / Corley, K. R. / Cornish, N. / Corre, D. / Corsi, A. / Cortese, S. / Costa, C. A. / Cotesta, R. / Coughlin, M. W. / Coughlin, S. B. / Coulon, J.-P. / Countryman, S. T. / Couvares, P. / Covas, P. B. / Coward, D. M. / Cowart, M. J. / Coyne, D. C. / Coyne, R. / Creighton, J. D. E. / Creighton, T. D. / Cripe, J. / Croquette, M. / Crowder, S. G. / Cudell, J.-R. / Cullen, T. J. / Cumming, A. / Cummings, R. / Cunningham, L. / Cuoco, E. / Curylo, M. / Canton, T. Dal / D'alya, G. / Dana, A. / Daneshgaran-Bajastani, L. M. / D'Angelo, B. / Danilishin, S. L. / D'Antonio, S. / Danzmann, K. / Darsow-Fromm, C. / Dasgupta, A. / Datrier, L. E. H. / Dattilo, V. / Dave, I. / Davier, M. / Davies, G. S. / Davis, D. / Daw, E. J. / DeBra, D. / Deenadayalan, M. / Degallaix, J. / Laurentis, M. De / Del'eglise, S. / Delfavero, M. / Lillo, N. De / Pozzo, W. Del / DeMarchi, L. M. / D'Emilio, V. / Demos, N. / Dent, T. / Pietri, R. De / Rosa, R. De / Rossi, C. De / DeSalvo, R. / Varona, O. de / Dhurandhar, S. / D'iaz, M. C. / Diaz-Ortiz, M. / Dietrich, T. / Fiore, L. Di / Fronzo, C. Di / Giorgio, C. Di / Giovanni, F. Di / Giovanni, M. Di / Girolamo, T. Di / Lieto, A. Di / Ding, B. / Pace, S. Di / Palma, I. Di / Renzo, F. Di / Divakarla, A. K. / Dmitriev, A. / Doctor, Z. / Donovan, F. / Dooley, K. L. / Doravari, S. / Dorrington, I. / Downes, T. P. / Drago, M. / Driggers, J. C. / Du, Z. / Ducoin, J.-G. / Dupej, P. / Durante, O. / D'Urso, D. / Dwyer, S. E. / Easter, P. J. / Eddolls, G. / Edelman, B. / Edo, T. B. / Edy, O. / Effler, A. / Ehrens, P. / Eichholz, J. / Eikenberry, S. S. / Eisenmann, M. / Eisenstein, R. 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E. / Sanchis-Gual, N. / Sanders, J. R. / Santiago, K. A. / Santos, E. / Sarin, N. / Sassolas, B. / Sathyaprakash, B. S. / Sauter, O. / Savage, R. L. / Savant, V. / Sawant, D. / Sayah, S. / Schaetzl, D. / Schale, P. / Scheel, M. / Scheuer, J. / Schmidt, P. / Schnabel, R. / Schofield, R. M. S. / Schonbeck, A. / Schreiber, E. / Schulte, B. W. / Schutz, B. F. / Schwarm, O. / Schwartz, E. / Scott, J. / Scott, S. M. / Seidel, E. / Sellers, D. / Sengupta, A. S. / Sennett, N. / Sentenac, D. / Sequino, V. / Sergeev, A. / Setyawati, Y. / Shaddock, D. A. / Shaffer, T. / Shahriar, M. S. / Sharma, A. / Sharma, P. / Shawhan, P. / Shen, H. / Shikauchi, M. / Shink, R. / Shoemaker, D. H. / Shoemaker, D. M. / Shukla, K. / ShyamSundar, S. / Siellez, K. / Sieniawska, M. / Sigg, D. / Singer, L. P. / Singh, D. / Singh, N. / Singha, A. / Singhal, A. / Sintes, A. M. / Sipala, V. / Skliris, V. / Slagmolen, B. J. J. / Slaven-Blair, T. J. / Smetana, J. / Smith, J. R. / Smith, R. J. E. / Somala, S. / Son, E. J. / Soni, S. / Sorazu, B. / Sordini, V. / Sorrentino, F. / Souradeep, T. / Sowell, E. / Spencer, A. P. / Spera, M. / Srivastava, A. K. / Srivastava, V. / Staats, K. / Stachie, C. / Standke, M. / Steer, D. A. / Steinhoff, J. / Steinke, M. / Steinlechner, J. / Steinlechner, S. / Steinmeyer, D. / Stevenson, S. / Stocks, D. / Stops, D. J. / Stover, M. / Strain, K. A. / Stratta, G. / Strunk, A. / Sturani, R. / Stuver, A. L. / Sudhagar, S. / Sudhir, V. / Summerscales, T. Z. / Sun, L. / Sunil, S. / Sur, A. / Suresh, J. / Sutton, P. J. / Swinkels, B. L. / Szczepa'nczyk, M. J. / Tacca, M. / Tait, S. C. / Talbot, C. / Tanasijczuk, A. J. / Tanner, D. B. / Tao, D. / T'apai, M. / Tapia, A. / Martin, E. N. Tapia San / Tasson, J. D. / Taylor, R. / Tenorio, R. / Terkowski, L. / Thirugnanasambandam, M. P. / Thomas, M. / Thomas, P. / Thompson, J. E. / Thondapu, S. R. / Thorne, K. A. / Thrane, E. / Tinsman, C. L. / Saravanan, T. R. / Tiwari, Shubhanshu / Tiwari, S. / Tiwari, V. / Toland, K. / Tonelli, M. / Tornasi, Z. / Torres-Forn'e, A. / Torrie, C. I. / Melo, I. Tosta e / Toyra, D. / Trail, E. A. / Travasso, F. / Traylor, G. / Tringali, M. C. / Tripathee, A. / Trovato, A. / Trudeau, R. J. / Tsang, K. W. / Tse, M. / Tso, R. / Tsukada, L. / Tsuna, D. / Tsutsui, T. / Turconi, M. / Ubhi, A. S. / Ueno, K. / Ugolini, D. / Unnikrishnan, C. S. / Urban, A. L. / Usman, S. A. / Utina, A. C. / Vahlbruch, H. / Vajente, G. / Valdes, G. / Valentini, M. / Bakel, N. van / Beuzekom, M. van / Brand, J. F. J. van den / Broeck, C. Van Den / Vander-Hyde, D. C. / Schaaf, L. van der / Heijningen, J. V. Van / Veggel, A. A. van / Vardaro, M. / Varma, V. / Vass, S. / Vas'uth, M. / Vecchio, A. / Vedovato, G. / Veitch, J. / Veitch, P. J. / Venkateswara, K. / Venugopalan, G. / Verkindt, D. / Veske, D. / Vetrano, F. / Vicer'e, A. / Viets, A. D. / Vinciguerra, S. / Vine, D. J. / Vinet, J.-Y. / Vitale, S. / Vivanco, Francisco Hernandez / Vo, T. / Vocca, H. / Vorvick, C. / Vyatchanin, S. P. / Wade, A. R. / Wade, L. E. / Wade, M. / Walet, R. / Walker, M. / Wallace, G. S. / Wallace, L. / Walsh, S. / Wang, J. Z. / Wang, S. / Wang, W. H. / Ward, R. L. / Warden, Z. A. / Warner, J. / Was, M. / Watchi, J. / Weaver, B. / Wei, L.-W. / Weinert, M. / Weinstein, A. J. / Weiss, R. / Wellmann, F. / Wen, L. / Wessels, P. / Westhouse, J. W. / Wette, K. / Whelan, J. T. / Whiting, B. F. / Whittle, C. / Wilken, D. M. / Williams, D. / Willis, J. L. / Willke, B. / Winkler, W. / Wipf, C. C. / Wittel, H. / Woan, G. / Woehler, J. / Wofford, J. K. / Wong, C. / Wright, J. L. / Wu, D. S. / Wysocki, D. M. / Xiao, L. / Yamamoto, H. / Yang, L. / Yang, Y. / Yang, Z. / Yap, M. J. / Yazback, M. / Yeeles, D. W. / Yu, Hang / Yu, Haocun / Yuen, S. H. R. / Zadro.zny, A. K. / Zadro.zny, A. / Zanolin, M. / Zelenova, T. / Zendri, J.-P. / Zevin, M. / Zhang, J. / Zhang, L. / Zhang, T. / Zhao, C. / Zhao, G. / Zhou, M. / Zhou, Z. / Zhu, X. J. / Zimmerman, A. B. / Zucker, M. E. / Zweizig, J.

Abstract: We report the observation of a compact binary coalescence involving a 22.2 - 24.3 $M_{\odot}$ black ... hole and a compact object with a mass of 2.50 - 2.67 $M_{\odot}$ (all measurements quoted at the 90$ ...

Abstract	We report the observation of a compact binary coalescence involving a 22.2 - 24.3 $M_{\odot}$ black hole and a compact object with a mass of 2.50 - 2.67 $M_{\odot}$ (all measurements quoted at the 90$\%$ credible level). The gravitational-wave signal, GW190814, was observed during LIGO's and Virgo's third observing run on August 14, 2019 at 21:10:39 UTC and has a signal-to-noise ratio of 25 in the three-detector network. The source was localized to 18.5 deg$^2$ at a distance of $241^{+41}_{-45}$ Mpc; no electromagnetic counterpart has been confirmed to date. The source has the most unequal mass ratio yet measured with gravitational waves, $0.112^{+0.008}_{-0.009}$, and its secondary component is either the lightest black hole or the heaviest neutron star ever discovered in a double compact-object system. The dimensionless spin of the primary black hole is tightly constrained to $\leq 0.07$. Tests of general relativity reveal no measurable deviations from the theory, and its prediction of higher-multipole emission is confirmed at high confidence. We estimate a merger rate density of 1-23 Gpc$^{-3}$ yr$^{-1}$ for the new class of binary coalescence sources that GW190814 represents. Astrophysical models predict that binaries with mass ratios similar to this event can form through several channels, but are unlikely to have formed in globular clusters. However, the combination of mass ratio, component masses, and the inferred merger rate for this event challenges all current models for the formation and mass distribution of compact-object binaries.
Keywords	covid19
Publisher	ArXiv
Document type	Article ; Online
DOI	10.3847/2041-8213/ab960f
Database	COVID19

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Article: Cross-cultural and factorial validity of PTSD check list-military version (PCL-M) in Sinhalese language.

Semage, Saveen N / Sivayogan, Sivagurunadan / Forbes, David / O'Donnell, Meaghan / Monaragala, Roshan M M / Lockwood, Emma / Dunt, David

European journal of psychotraumatology

2013 Volume 4

Abstract: ... Version (PCL-M) translated into Sinhalese.: Methods: Expert committee consensus generation as well ... equivalence of the Sinhalese and English versions of the PCL-M. Four translations of each item were made ... for the PCL-M (SIN), the study utilized more informal checks for assessment of validity and Sri Lankan cutoffs ...

Abstract	Background: There are currently no validated instruments to assess the burden of combat-related Posttraumatic Stress Disorder (PTSD) in Sinhalese-the main spoken language in Sri Lanka. Objective: The purpose of this research was to establish the cross-cultural and structural validity of the PTSD Check List-Military Version (PCL-M) translated into Sinhalese. Methods: Expert committee consensus generation as well as translation-back translation approaches were used to establish the semantic, conceptual, and content equivalence of the Sinhalese and English versions of the PCL-M. Four translations of each item were made. In the absence of any "gold standard" psychometric instrument in Sinhalese to establish the criterion validity for the PCL-M (SIN), the study utilized more informal checks for assessment of validity and Sri Lankan cutoffs for caseness for PTSD to establish the psychometric strength of the translated instrument along with standard reliability analysis. Confirmatory factor analysis was performed on PCL-M scoring of a random sample of 1,586 soldiers to examine construct validity. Results: Thirteen of the 17 items were selected by popular vote, and the remaining 4 through discussion and consensus. Reliability measured by Cronbach's-α was 0.944 for the total scale and 0.812, 0.869, and 0.895 for the three DSM-IV sub-scales (re-experiencing, avoidance/numbing, and hyperarousal), respectively. The desired cutoff point for the translated instrument was determined to be 44. The five-factor model by Elhai et al. and the four-factor model by King et al. fitted best, demonstrating good fit to all three fit indices, while the four-factor model and the DSM-IV three-factor model by Simms et al. only had acceptable levels of fit for root mean squared error of approximation. χ(2) difference test comparing the two better-fitting models suggests that the five-factor model by Elhai et al. has the better fit. Conclusion: The PCL-M (SIN) version is suitable for use in the study of PTSD in the Sri Lankan military forces, as judged by cross-cultural and construct validity as well as reliability.
Language	English
Publishing date	2013-02-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2586642-4
ISSN	2000-8066 ; 2000-8066 ; 2000-8198
ISSN (online)	2000-8066
ISSN	2000-8066 ; 2000-8198
DOI	10.3402/ejpt.v4i0.19707
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Book ; Online ; E-Book: Creasy-Resnik's Study Guide for Maternal Fetal Medicine

Lockwood, Charles J. / Moore, Thomas / Copel, Joshua / Silver, Robert M. / Resnik, Robert / Louis, Judette / Dugoff, Lorraine

2023

Subject code	618.2
Language	English
Size	1 online resource (580 pages)
Edition	1st ed.
Publisher	Elsevier
Publishing place	Philadelphia
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	0-323-83498-1 ; 0-323-83497-3 ; 978-0-323-83498-8 ; 978-0-323-83497-1
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Clarification of Information in "Navigating Next-Generation Sequencing Laboratory Developed Tests: A Critical Look at Proficiency Testing, US Food and Drug Administration Regulations, and Clinical Laboratory Performance Tests".

Lockwood, Christina M

Archives of pathology & laboratory medicine

2024 Volume 148, Issue 5, Page(s) 507

MeSH term(s)	United States ; United States Food and Drug Administration ; Humans ; High-Throughput Nucleotide Sequencing ; Laboratory Proficiency Testing ; Laboratories, Clinical
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Letter ; Journal Article
ZDB-ID	194119-7
ISSN	1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
ISSN (online)	1543-2165
ISSN	0363-0153 ; 0096-8528 ; 0003-9985
DOI	10.5858/arpa.2023-0593-LE
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Article ; Online: Cross-cultural and factorial validity of PTSD check list—military version (PCL-M) in Sinhalese language

Saveen N. Semage / Sivagurunadan Sivayogan / David Forbes / Meaghan O'Donnell / Roshan M. M. Monaragala / Emma Lockwood / David Dunt

European Journal of Psychotraumatology, Vol 4, Iss 0, Pp 1-

2013 Volume 8

Abstract: ... Version (PCL-M) translated into Sinhalese. Methods: Expert committee consensus generation as well ... equivalence of the Sinhalese and English versions of the PCL-M. Four translations of each item were made ... the criterion validity for the PCL-M (SIN), the study utilized more informal checks for assessment of validity ...

Abstract	Background: There are currently no validated instruments to assess the burden of combat-related Posttraumatic Stress Disorder (PTSD) in Sinhalese—the main spoken language in Sri Lanka. Objective: The purpose of this research was to establish the cross-cultural and structural validity of the PTSD Check List—Military Version (PCL-M) translated into Sinhalese. Methods: Expert committee consensus generation as well as translation–back translation approaches were used to establish the semantic, conceptual, and content equivalence of the Sinhalese and English versions of the PCL-M. Four translations of each item were made. In the absence of any “gold standard” psychometric instrument in Sinhalese to establish the criterion validity for the PCL-M (SIN), the study utilized more informal checks for assessment of validity and Sri Lankan cutoffs for caseness for PTSD to establish the psychometric strength of the translated instrument along with standard reliability analysis. Confirmatory factor analysis was performed on PCL-M scoring of a random sample of 1,586 soldiers to examine construct validity. Results: Thirteen of the 17 items were selected by popular vote, and the remaining 4 through discussion and consensus. Reliability measured by Cronbach's-α was 0.944 for the total scale and 0.812, 0.869, and 0.895 for the three DSM-IV sub-scales (re-experiencing, avoidance/numbing, and hyperarousal), respectively. The desired cutoff point for the translated instrument was determined to be 44. The five-factor model by Elhai et al. and the four-factor model by King et al. fitted best, demonstrating good fit to all three fit indices, while the four-factor model and the DSM-IV three-factor model by Simms et al. only had acceptable levels of fit for root mean squared error of approximation. χ2 difference test comparing the two better-fitting models suggests that the five-factor model by Elhai et al. has the better fit. Conclusion: The PCL-M (SIN) version is suitable for use in the study of PTSD in the Sri Lankan military forces, as judged by cross-cultural and construct validity as well as reliability.
Keywords	PTSD ; PCL-M ; Sri Lanka Army ; cross-cultural validation ; factorial validity ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Psychiatry ; RC435-571
Subject code	150
Language	English
Publishing date	2013-02-01T00:00:00Z
Publisher	Co-Action Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Single nucleotide polymorphism analysis of European archaeological M. leprae DNA.

Watson, Claire L / Lockwood, Diana N J

PloS one

2009 Volume 4, Issue 10, Page(s) e7547

Abstract: ... of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and ... may assist in the understanding of M. leprae evolution.: Methods and findings: Skeletons have been exhumed ... single nucleotide polymorphisms (SNPs) in 10 aDNA extractions. M. leprae aDNA was extracted from 6 of the 10 bone samples. SNP ...

Abstract	Background: Leprosy was common in Europe eight to twelve centuries ago but molecular confirmation of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and single nucleotide polymorphism (SNP) typed the DNA, this provides insight into the pattern of leprosy transmission in Europe and may assist in the understanding of M. leprae evolution. Methods and findings: Skeletons have been exhumed from 3 European countries (the United Kingdom, Denmark and Croatia) and are dated around the medieval period (476 to 1350 A.D.). we tested for the presence of 3 previously identified single nucleotide polymorphisms (SNPs) in 10 aDNA extractions. M. leprae aDNA was extracted from 6 of the 10 bone samples. SNP analysis of these 6 extractions were compared to previously analysed European SNP data using the same PCR assays and were found to be the same. Testing for the presence of SNPs in M. leprae DNA extracted from ancient bone samples is a novel approach to analysing European M. leprae DNA and the findings concur with the previously published data that European M. leprae strains fall in to one group (SNP group 3). Conclusions: These findings support the suggestion that the M. leprae genome is extremely stable and show that archaeological M. leprae DNA can be analysed to gain detailed information about the genotypic make-up of European leprosy, which may assist in the understanding of leprosy transmission worldwide.
MeSH term(s)	Archaeology/methods ; Bacterial Typing Techniques/methods ; Base Sequence ; DNA Fingerprinting ; DNA, Bacterial/genetics ; Europe ; Genotype ; Humans ; Leprosy/microbiology ; Molecular Sequence Data ; Mycobacterium leprae/genetics ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single Nucleotide
Chemical Substances	DNA, Bacterial
Language	English
Publishing date	2009-10-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0007547
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Transforming the grid for a more environmentally and socially sustainable electricity system in Great Britain is a slow and uneven process.

Lockwood, Matthew

Proceedings of the National Academy of Sciences of the United States of America

2023 Volume 120, Issue 47, Page(s) e2207825120

Abstract: Electricity system decarbonization is key for environmental sustainability. From a consumption-production perspective, much attention has been paid to changes in how electricity is generated and used, but electricity systems also rely on a grid ... ...

Abstract	Electricity system decarbonization is key for environmental sustainability. From a consumption-production perspective, much attention has been paid to changes in how electricity is generated and used, but electricity systems also rely on a grid infrastructure that connects and integrates production and consumption, and which will also need to transform. At the same time, new technologies in the electricity system, including the grid, offer the potential for more socially sustainable ways of producing and consuming energy. However, in practice, change has been slow, uneven, and often dysfunctional. A socio-technical transitions approach offers insights into why this is so, seeing electricity system change not simply in technical and economic terms, but also as the outcomes of interactions between technology and social and political processes. The approach draws attention to the particular challenges of achieving rapid transitions in complex critical infrastructures like electricity with strong institutional logics of security. This article applies this approach to the case of Great Britain, where despite strong commitments to sustainability in the form of high-level climate policy, the electricity grid has often been a constraint on the pace of change. The nature of the British transition is explained partly by weak links between these high-level goals on the one hand and the detailed rules and practices in the electricity system on the other. It is also explained by patterns of ownership and grid regulation in the British case that protect incumbents and make it difficult for new actors to develop the system in more socially sustainable directions.
Language	English
Publishing date	2023-11-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2207825120
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Article: An Address to the American People.

Lockwood, M L

The Homoeopathic physician

2023 Volume 19, Issue 10, Page(s) 465–467

Language	English
Publishing date	2023-05-01
Publishing country	United States
Document type	Journal Article
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