LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 131908

Search options

  1. Article ; Online: Diasporic Condition: Jane Jin Kaisen's

    Kim, Soyi

    Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

    2021  Volume 22, Issue 4, Page(s) 413–425

    Abstract: Jane Jin Kaisen's 2017 video work, ...

    Abstract Jane Jin Kaisen's 2017 video work,
    MeSH term(s) Humans ; Republic of Korea ; Sexual Behavior
    Language English
    Publishing date 2021-06-01
    Publishing country England
    Document type Journal Article
    ISSN 1529-9740
    ISSN (online) 1529-9740
    DOI 10.1080/15299732.2021.1925862
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article: Studies on Preformulation and Formulation of JIN-001 Liquisolid Tablet with Enhanced Solubility.

    Kim, Han-Sol / Kim, Chang-Min / Jo, An-Na / Kim, Joo-Eun

    Pharmaceuticals (Basel, Switzerland)

    2022  Volume 15, Issue 4

    Abstract: ... JIN-001, a novel Hsp90 inhibitor, was reported to have substantial in vitro antiproliferative and ... in vivo antitumor activity; however, JIN-001 was a crystalline solid with very low solubility ... as an optimal liquid vehicle based on solubility studies. JIN-001 liquisolid (JLS) powder was successfully ...

    Abstract This study aimed to develop a heat shock protein 90 (Hsp90) inhibitor liquisolid tablet with improved solubility to overcome low bioavailability issues. As an active pharmaceutical ingredient (API), JIN-001, a novel Hsp90 inhibitor, was reported to have substantial in vitro antiproliferative and in vivo antitumor activity; however, JIN-001 was a crystalline solid with very low solubility in an aqueous solution, and therefore, Capryol 90, which has excellent solubilization ability, was selected as an optimal liquid vehicle based on solubility studies. JIN-001 liquisolid (JLS) powder was successfully prepared by dissolving JIN-001 in Capryol 90 and mixing colloidal silicon dioxide (CSD) used as an oil adsorption agent. The prepared JLS was confirmed to be amorphous. Based on the result of the solubility test of JLS, compared to JIN-001, the solubility of the former was significantly improved in all solvents regardless of pH. JLS tablets were prepared through wet granulation using JIN-001 and stable excipients based on the compatibility test. The developed JLS tablet significantly increased the drug release rate in all tested solutions; however, the liquisolid method had no significant effect on bioavailability in the pharmacokinetics study in beagle dogs. In conclusion, the liquisolid system influenced the solubility and dissolution rate of JIN-001.
    Language English
    Publishing date 2022-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph15040412
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Studies on Preformulation and Formulation of JIN-001 Liquisolid Tablet with Enhanced Solubility

    Han-Sol Kim / Chang-Min Kim / An-Na Jo / Joo-Eun Kim

    Pharmaceuticals, Vol 15, Iss 4, p

    2022  Volume 412

    Abstract: ... JIN-001, a novel Hsp90 inhibitor, was reported to have substantial in vitro antiproliferative and ... in vivo antitumor activity; however, JIN-001 was a crystalline solid with very low solubility ... as an optimal liquid vehicle based on solubility studies. JIN-001 liquisolid (JLS) powder was successfully ...

    Abstract This study aimed to develop a heat shock protein 90 (Hsp90) inhibitor liquisolid tablet with improved solubility to overcome low bioavailability issues. As an active pharmaceutical ingredient (API), JIN-001, a novel Hsp90 inhibitor, was reported to have substantial in vitro antiproliferative and in vivo antitumor activity; however, JIN-001 was a crystalline solid with very low solubility in an aqueous solution, and therefore, Capryol 90, which has excellent solubilization ability, was selected as an optimal liquid vehicle based on solubility studies. JIN-001 liquisolid (JLS) powder was successfully prepared by dissolving JIN-001 in Capryol 90 and mixing colloidal silicon dioxide (CSD) used as an oil adsorption agent. The prepared JLS was confirmed to be amorphous. Based on the result of the solubility test of JLS, compared to JIN-001, the solubility of the former was significantly improved in all solvents regardless of pH. JLS tablets were prepared through wet granulation using JIN-001 and stable excipients based on the compatibility test. The developed JLS tablet significantly increased the drug release rate in all tested solutions; however, the liquisolid method had no significant effect on bioavailability in the pharmacokinetics study in beagle dogs. In conclusion, the liquisolid system influenced the solubility and dissolution rate of JIN-001.
    Keywords JIN-001 ; heat shock protein 90 inhibitor ; capryol 90 ; colloidal silicon dioxide ; liquisolid ; solubility ; Medicine ; R ; Pharmacy and materia medica ; RS1-441
    Subject code 500
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Correction: Kim, Young-Gun; Jeon, Ja Young; Kim, Hae Jin; Kim, Dae Jung; Lee, Kwan-Woo; Moon, So Young; Han, Seung Jin. Risk of Dementia in Older Patients with Type 2 Diabetes on Dipeptidyl-Peptidase IV Inhibitors versus Sulfonylureas: A Real-World Population-Based Cohort Study.

    Kim, Young-Gun / Jeon, Ja Young / Kim, Hae Jin / Kim, Dae Jung / Lee, Kwan-Woo / Moon, So Young / Han, Seung Jin

    Journal of clinical medicine

    2019  Volume 8, Issue 3

    Abstract: The authors wish to make the following corrections to this paper [ ... ]. ...

    Abstract The authors wish to make the following corrections to this paper [...].
    Language English
    Publishing date 2019-03-20
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm8030389
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Response by Jin et al to Letter Regarding Article, "Atrial Fibrillation Catheter Ablation Improves 1-Year Follow-Up Cognitive Function, Especially in Patients With Impaired Cognitive Function".

    Jin, Moo-Nyun / Kim, Tae-Hoon / Kang, Ki-Woon / Yu, Hee Tae / Uhm, Jae-Sun / Joung, Boyoung / Lee, Moon-Hyoung / Kim, Eosu / Pak, Hui-Nam

    Circulation. Arrhythmia and electrophysiology

    2019  Volume 12, Issue 10, Page(s) e007880

    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation ; Cognition ; Follow-Up Studies ; Humans ; Pulmonary Veins/surgery
    Language English
    Publishing date 2019-10-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2426129-4
    ISSN 1941-3084 ; 1941-3149
    ISSN (online) 1941-3084
    ISSN 1941-3149
    DOI 10.1161/CIRCEP.119.007880
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6667: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Letter: Serum Concentrations of Ghrelin and Leptin according to Thyroid Hormone Condition, and Their Correlations with Insulin Resistance (Endocrinol Metab 2015;30:318-25, Kyu-Jin Kim et al.).

    Kim, Jin Hwa

    Endocrinology and metabolism (Seoul, Korea)

    2015  Volume 30, Issue 4, Page(s) 631–632

    Language English
    Publishing date 2015-12
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2802452-7
    ISSN 2093-5978 ; 2093-596X
    ISSN (online) 2093-5978
    ISSN 2093-596X
    DOI 10.3803/EnM.2015.30.4.631
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Vaginal prolapse by ovarian follicular cysts in a female Jin-do dog

    Kim, B.S. (Chonnam National University, Gwangju, Republic of Korea) / Kim, H.S. (Chonnam National University, Gwangju, Republic of Korea) / Kim, K.C. (Chonnam National University, Gwangju, Republic of Korea) / Park, C.H. (Chonnam National University, Gwangju, Republic of Korea) / Oh, K.S. (Chonnam National University, Gwangju, Republic of Korea) / Son, C.H. (Chonnam National University, Gwangju, Republic of Korea), E-mail: chson@chonnam.ac.kr

    Korean Journal of Veterinary Research

    (Jun 2008)  Volume v. 48, Issue (2), Page(s) p. 223–225

    Abstract: A six-year-old, female Jin-do dog was referred for the recurrence of vaginal prolapse. Less than 7 ...

    Abstract A six-year-old, female Jin-do dog was referred for the recurrence of vaginal prolapse. Less than 7 months previously, the dog with the vaginal prolapse had been treated with hormone therapy because ultrasonography had identified a single follicular cyst in the left ovary. Three months after the first visit, the dog came into heat and the vaginal prolapse recurred. Ultrasonography showed multiple follicular cysts in both ovaries and radioimmunoassay detected a plasma estradiol-17β concentration of 13.3 pg/ml. Treatment involved the repositioning of the vaginal prolapsed, ovariohysterectomy and the resection of the protruding tissue. The dog had been completely recovered two months later after the treatment.
    Keywords OVARIAN CYSTS ; ECHOGRAPHY ; ULTRASONICS ; VAGINAL DISEASES ; KYSTE OVARIEN ; ECHOGRAPHIE ; ULTRASON ; MALADIE DU VAGIN ; QUISTE OVARICO ; ECOGRAFIA ; ULTRASONIDO ; ENFERMEDADES DE LA VAGINA
    Language English
    Document type Article
    ISSN 1225-0198
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Inhibitory effect of immunoglobulin E production by jin-deuk-chal (Siegesbeckia orientalis).

    Hwang, W J / Park, E J / Jang, C H / Han, S W / Oh, G J / Kim, N S / Kim, H M

    Immunopharmacology and immunotoxicology

    2001  Volume 23, Issue 4, Page(s) 555–563

    Abstract: Elevated levels of immunoglobulin (Ig) E are associated with immediate-type allergic reactions. Jin ...

    Abstract Elevated levels of immunoglobulin (Ig) E are associated with immediate-type allergic reactions. Jin-deuk-chal is the whole plant of Siegesbeckia orientalis (SO) sL Immunization of mice with small amounts of protein antigens on alum results in several fold increases in total plasma IgE, much of it specific for the immunizing antigen. In the present study, we investigated the effect of Siegesbeckia orientalis (SO) on IgE production. SO inhibited the plasma levels of IgE induced by antigens. The effects of SO on the interleukin (IL)-4-dependent IgE response by mouse whole spleen cells were studied. IL-4 dependent IgE production of lipopolysaccharide (LPS)-stimulated whole spleen cells was inhibited by SO. In addition, using U266B I human IgE-bearing B cells, we found that SO inhibited the production of IgE activated by LPS plus IL-4. These results suggest that SO have antiallergic activity by inhibition of IgE production from B cells.
    MeSH term(s) Animals ; Asteraceae ; B-Lymphocytes/drug effects ; B-Lymphocytes/immunology ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Immunoglobulin E/biosynthesis ; Interleukin-4/immunology ; Lipopolysaccharides/pharmacology ; Mice ; Mice, Inbred ICR ; Plant Extracts/pharmacology ; Spleen/drug effects ; Spleen/immunology ; Tumor Cells, Cultured
    Chemical Substances Lipopolysaccharides ; Plant Extracts ; Interleukin-4 (207137-56-2) ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2001-12-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 807033-7
    ISSN 1532-2513 ; 0892-3973
    ISSN (online) 1532-2513
    ISSN 0892-3973
    DOI 10.1081/iph-100108601
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1481: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Local institutional investors, information asymmetries, and equity returns /Bok Baik, Jun-Koo Kang, Jin-Mo Kim

    Baik, Bok / Kang, Jun-koo / Kim, Jin-mo

    Journal of financial economics Vol. 97, No. 1 , p. 81-106

    2010  Volume 97, Issue 1, Page(s) 81–106

    Keywords Institutioneller Investor ; Asymmetrische Information ; Home Bias Puzzle ; Kapitaleinkommen ; Theorie
    Language English
    Publisher Elsevier
    Publishing place Amsterdam [u.a.] ; Jena
    Document type Article
    ZDB-ID 187118-3
    ISSN 0304-405X
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article: [Rezension von: Kim, Chang-Jin, ...,, State-space models with regime switching]

    Balke, Nathan S / Kim, Chang-jin

    Journal of economic literature Vol. 39, No. 1 , p. 127-128

    2001  Volume 39, Issue 1, Page(s) 127–128

    Author's details Nathan S. Balke
    Keywords 40#49
    Language English
    Publisher Assoc
    Publishing place Nashville, Tenn
    Document type Article
    ZDB-ID 3076-4 ; 2010159-4
    ISSN 0022-0515
    ISSN 0022-0515
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top