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  1. Article ; Online: 2021 ESC guidelines on cardiac pacing and cardiac resynchronization: what is the correct level of evidence for the superiority of cephalic vein cutdown? C, B or maybe A?

    Iliodromitis, Konstantinos / Deftereos, Spyridon G / Bogossian, Harilaos

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2022  Volume 24, Issue 4, Page(s) 697

    MeSH term(s) Cardiac Resynchronization Therapy ; Humans ; Veins ; Venous Cutdown
    Language English
    Publishing date 2022-02-16
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euac001
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    Zs.A 5434: Show issues Location:
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  2. Article ; Online: Heroes, politics and media: the unshakable medical practice in the pandemic.

    Vrachatis, Dimitrios A / Deftereos, Spyridon G / Lansky, Alexandra

    European heart journal

    2021  Volume 42, Issue 27, Page(s) 2622–2625

    MeSH term(s) Communications Media ; Humans ; Pandemics ; Politics
    Language English
    Publishing date 2021-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab101
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    Zs.A 1563: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 640: Show issues

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  3. Article ; Online: Colchicine administered early in acute myocardial infarction: ready, set … go?

    Vrachatis, Dimitrios A / Giannopoulos, Georgios V / Deftereos, Spyridon G

    European heart journal

    2021  Volume 42, Issue 28, Page(s) 2802

    MeSH term(s) Colchicine ; Humans ; Myocardial Infarction/drug therapy ; Percutaneous Coronary Intervention
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-02-08
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehab010
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    Zs.A 1563: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Myocardial Injury in COVID-19-Can We Successfully Target Inflammation?

    Giannopoulos, Georgios / Vrachatis, Dimitrios A / Deftereos, Spyridon G

    JAMA cardiology

    2020  Volume 5, Issue 9, Page(s) 1069–1070

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Fatal Outcome ; Humans ; Inflammation ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-03
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2020.2569
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  5. Article ; Online: STEMI in COVID-19 patients: thrombolysis-first approach could yield more risk than benefit.

    Vrachatis, Dimitrios A / Deftereos, Spyridon / Stefanini, Giulio G

    European heart journal

    2020  Volume 41, Issue 42, Page(s) 4141–4142

    MeSH term(s) COVID-19 ; Cardiologists ; Cardiology ; China ; Humans ; Pandemics ; SARS-CoV-2 ; ST Elevation Myocardial Infarction/therapy ; Thrombolytic Therapy
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehaa477
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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Hunting the Vulnerable Carotid Plaque: All That Glitters May Not Be Gold.

    Vrachatis, Dimitrios A / Papaioannou, Theodore G / Deftereos, Spyridon / Reimers, Bernhard

    Ultrasound in medicine & biology

    2020  Volume 46, Issue 11, Page(s) 3168

    MeSH term(s) Carotid Arteries ; Gold ; Humans ; Plaque, Atherosclerotic
    Chemical Substances Gold (7440-57-5)
    Language English
    Publishing date 2020-08-08
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2020.04.039
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    Zs.A 963: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: Efficacy, Safety and Feasibility of Superior Vena Cava Isolation in Patients Undergoing Atrial Fibrillation Catheter Ablation: An Up-to-Date Review.

    Vrachatis, Dimitrios A / Papathanasiou, Konstantinos A / Kossyvakis, Charalampos / Giotaki, Sotiria G / Deftereos, Gerasimos / Kousta, Maria S / Iliodromitis, Konstantinos E / Bogossian, Harilaos / Avramides, Dimitrios / Giannopoulos, George / Lambadiari, Vaia / Siasos, Gerasimos / Papaioannou, Theodore G / Deftereos, Spyridon

    Biomedicines

    2023  Volume 11, Issue 4

    Abstract: Pulmonary vein isolation (PVI) is the cornerstone in atrial fibrillation (AF) ablation; yet, the role of arrhythmogenic superior vena cava (SVC) is increasingly recognized and different ablation strategies have been employed in this context. SVC can act ... ...

    Abstract Pulmonary vein isolation (PVI) is the cornerstone in atrial fibrillation (AF) ablation; yet, the role of arrhythmogenic superior vena cava (SVC) is increasingly recognized and different ablation strategies have been employed in this context. SVC can act as a trigger or perpetuator of AF, and its significance might be more pronounced in patients undergoing repeated ablation. Several cohorts have examined efficacy, safety and feasibility of SVC isolation (SVCI) among AF patients. The majority of these studies explored as-needed SVCI during index PVI, and only a minority of them included repeated ablation subjects and non-radiofrequency energy sources. Studies of heterogeneous design and intent have explored both empiric and as-needed SVCI on top of PVI and reported inconclusive results. These studies have largely failed to demonstrate any clinical benefit in terms of arrhythmia recurrence, although safety and feasibility are undisputable. Mixed population demographics, small number of enrollees and short follow-up are the main limitations. Procedural and safety data are comparable between empiric SVCI and as-needed SVCI, and some studies suggested that empiric SVCI might be associated with reduced AF recurrences in paroxysmal AF patients. Currently, no study has compared different ablation energy sources in the setting of SVCI, and no randomized study has addressed as-needed SVCI on top of PVI. Furthermore, data regarding cryoablation are still in their infancy, and regarding SVCI in patients with cardiac devices more safety and feasibility data are needed. PVI non-responders, patients undergoing repeated ablation and patients with long SVC sleeves could be potential candidates for SVCI, especially via an empiric approach. Although many technical aspects remain unsettled, the major question to answer is which clinical phenotype of AF patients might benefit from SVCI?
    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11041022
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  8. Article ; Online: Editorial: Colchicine: Conventional and Contemporary Indications.

    Vrachatis, Dimitrios A / Giannopoulos, Georgios / Deftereos, Spyridon G

    Current pharmaceutical design

    2018  Volume 24, Issue 6, Page(s) 647

    MeSH term(s) Colchicine/therapeutic use ; Gout/drug therapy ; Humans
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2018-05-16
    Publishing country United Arab Emirates
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/138161282406180510170818
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    Zs.A 4714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Myocardial Injury in COVID-19—Can We Successfully Target Inflammation?

    Giannopoulos, Georgios / Vrachatis, Dimitrios A. / Deftereos, Spyridon G.

    JAMA Cardiology

    2020  Volume 5, Issue 9, Page(s) 1069

    Keywords covid19
    Language English
    Publisher American Medical Association (AMA)
    Publishing country us
    Document type Article ; Online
    ISSN 2380-6583
    DOI 10.1001/jamacardio.2020.2569
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Left atrial appendage morphofunctional indices could be predictive of arrhythmia recurrence post-atrial fibrillation ablation: a meta-analysis.

    Papathanasiou, Konstantinos A / Vrachatis, Dimitrios A / Kazantzis, Dimitrios / Kossyvakis, Charalampos / Giotaki, Sotiria G / Deftereos, Gerasimos / Raisakis, Konstantinos / Kaoukis, Andreas / Avramides, Dimitrios / Lambadiari, Vaia / Siasos, Gerasimos / Deftereos, Spyridon

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2023  Volume 75, Issue 1, Page(s) 29

    Abstract: Background: Left atrium changes are implicated in atrial fibrillation (AF) substrate and are predictive of AF outcomes. Left atrial appendage (LAA) is an integral component of left atrial structure and could be affected by atrial cardiomyopathy. We ... ...

    Abstract Background: Left atrium changes are implicated in atrial fibrillation (AF) substrate and are predictive of AF outcomes. Left atrial appendage (LAA) is an integral component of left atrial structure and could be affected by atrial cardiomyopathy. We aimed to elucidate the association between LAA indices and late arrhythmia recurrence after atrial fibrillation catheter ablation (AFCA).
    Methods: The MEDLINE database, ClinicalTrials.gov, medRxiv and Cochrane Library were searched for studies evaluating LAA and late arrhythmia recurrence in patients undergoing AFCA. Data were pooled by meta-analysis using a random-effects model. The primary endpoint was pre-ablation difference in LAA anatomic or functional indices.
    Results: A total of 34 studies were found eligible and five LAA indices were analyzed. LAA ejection fraction and LAA emptying velocity were significantly lower in patients with AF recurrence post-ablation [SMD = - 0.66; 95% CI (- 1.01, - 0.32) and SMD = - 0.56; 95% CI (- 0.73, - 0.40) respectively] as compared to arrhythmia free controls. LAA volume and LAA orifice area were significantly higher in patients with AF recurrence post-ablation (SMD = 0.51; 95% CI 0.35-0.67, and SMD = 0.35; 95% CI 0.20-0.49, respectively) as compared to arrhythmia free controls. LAA morphology was not predictive of AF recurrence post-ablation (chicken wing morphology; OR 1.27; 95% CI 0.79-2.02). Moderate statistical heterogeneity and small case-control studies are the main limitations of our meta-analysis.
    Conclusions: Our findings suggest that LAA ejection fraction, LAA emptying velocity, LAA orifice area and LAA volume differ between patients suffering from arrhythmia recurrence post-ablation and arrhythmia free counterparts, while LAA morphology is not predictive of AF recurrence.
    Language English
    Publishing date 2023-04-20
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-023-00356-3
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