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  1. Article: Hear the Ear: Gear up, Diabetes Care.

    Kalra, Sanjay / Kaur, Navjot

    The Journal of the Association of Physicians of India

    2023  Volume 71, Issue 6, Page(s) 11–12

    MeSH term(s) Humans ; Diabetes Mellitus/therapy
    Language English
    Publishing date 2023-06-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 313: Show issues Location:
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  2. Article: Characterization of seed-to-seedling transmission of

    Kaur, Navjot / Dutta, Bhabesh

    Plant disease

    2024  

    Abstract: Alternaria brassicicola is a part of a complex of Alternaria species that causes leaf blight and head rot in brassica crops such as broccoli, kale, cabbage, cauliflower, and collards. Seed can serve as a potential source of inoculum for the transmission ... ...

    Abstract Alternaria brassicicola is a part of a complex of Alternaria species that causes leaf blight and head rot in brassica crops such as broccoli, kale, cabbage, cauliflower, and collards. Seed can serve as a potential source of inoculum for the transmission of A. brassicicola in broccoli as demonstrated earlier; however, seed-to-seedling transmission of pathogen was never characterized empirically. Hence, the objectives of this study were to (i) re-evaluate the effect of artificial seed infestation on seed germination and seed-to-seedling transmission of A. brassicicola in broccoli; (ii) determine the effect of A. brassicicola-seed inoculum levels on seed-to-seedling transmission; (iii) evaluate if variations in A. brassicicola -aggressiveness impact A. brassicicola seed-to-seedling transmission and, (iv) evaluate seed treatments that can reduce seed-to-seedling transmission of A. brassicicola in broccoli. Artificially infested seedlots were generated by inoculating broccoli seeds with a spore suspension of 1 × 105 conidia/ml of A. brassicicola using vacuum infiltration method. Inoculated (n=10 seedlots; 300 seeds/seedlot) or control seedlots in three replicates were planted on two layers of sterile blotter paper saturated with sterile water in transparent plastic boxes and incubated at 20°C and >90% RH under continuous fluorescent light. Percent seed germination and percent seed-to-seedling transmission were recorded every other day until 21 days. Percent seed germination was significantly affected with artificial pathogen inoculation. One hundred percent of the seedlots transmitted the pathogen to broccoli seedlings and seed-to-seedling percentages of the seedlots varied considerably. A strong linear and significant relationship between A. brassicicola inoculum level and seed-to-seedling transmission (%) within each seedlot was observed. Interestingly, variations in aggresiveness of A. brassicicola isolates did not affect seed-to-seedling transmission, as 100% of the seedlots were able to transmit the pathogen. Seed treatment with Miravis (a.i. pydiflumetofen 18.3%) significantly increased seed germination and reduced seed-to-seedling transmission percentages in A. brassicicola-inoculated seedlots. These results indicate that artificial seed inoculation with A. brassicicola can result in consistent seed-to-seedling transmission with significant impact on seed germination. Seed inoculum density of ≥104 conidia/ml is necesssary for reliable transmission of A. brassicicola. Further seed-to-sedling transmission is not dependent on aggresiveness of A. brassicicola isolates and, seed treatment with Miravis can significantly reduce pathogen transmission in broccoli seedings. Overall, this study provides detailed characterization of seed-to-seedling transmission of A. brassicicola in broccoli that can be further used to determine inoculum threshold, which has potential applications in seed-health testing and sample size determination. Further we also provide options for effective seed treatments that can significantly reduce A. brassicicola seed-to-seedling transmission and may potentially aid in managing seedborne fungal infection.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-10-23-2002-RE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Aggressive

    Kaur, Navjot / Dutta, Bhabesh

    Plant disease

    2024  

    Abstract: Alternaria brassicicola is a part of Alternaria complex that causes leaf blight and head rot (ABHR) in brassica crops. Infested broccoli seeds can play an important role in introducing A. brassicicola in transplant houses and production fields. However, ... ...

    Abstract Alternaria brassicicola is a part of Alternaria complex that causes leaf blight and head rot (ABHR) in brassica crops. Infested broccoli seeds can play an important role in introducing A. brassicicola in transplant houses and production fields. However, characterization of natural seed infestation and seed-to-seedling transmission of A. brassicicola in broccoli is yet to be demonstrated. In this research we characterized Alternaria spp. isolates from commercial broccoli seedlots for their species identity, pathogenicity and aggressiveness on broccoli and their sensitivity to Quinone-outside inhibitor (QoI) fungicide (azoxystrobin). Two hundred commercial seedlots from two broccoli cultivars; Cultivar 1 (EC; n=100 seedlots) and Cultivar 2 (ED; n=100 seedlots) were evaluated for the presence of A. brassicicola under in-vitro conditions using a seedling grow-out assay. Alternaria spp. was detected in 31 and 28% of the commercial seedlots of Cultivar 1 and Cultivar 2, respectively. The seed-to-seedling transmission (%) varied considerably within each positive infested seedlot, which ranged from 1.3 to 17.3%. Subsequent molecular identification of single spore cultures (n=138) was made by sequencing four housekeeping genes; actin, the major allergen (Alta1), plasma membrane ATPase and Glyceraldehyde-3-phosphate dehydrogenase (GPD), and later the sequences were concatenated and compared for the phylogenetic distance with diverse Alternaria species. Ninety-six percent (n=133) of the isolates formed a cluster with a known A. brassicicola based on multigene phylogeny, which were later confirmed as A. brassicicola using a species-specific PCR assay. One hundred percent of the A. brassicicola seed isolates (n=133) were either highly- or moderately- aggressive on broccoli (cv. Emerald Crown) based on a detached leaf assay. Sensitivity of representative A. brassicicola isolates (n=58) to azoxystrobin was evaluated using a spore germination assay and the EC50 values (effective fungicide concentration (ppm) at which germination of conidia of isolates were reduced by 50% compared to control) for each isolate was determined. A. brassicicola isolates from naturally infested commercial broccoli seeds were sensitive to azoxystrobin with considerably low EC50 values in the range of <0.0001 ppm to 0.33 ppm; however, there were a few isolates (14%), which showed 100-fold reduced sensitivity from the most sensitive isolate (EC50 =0.0001 ppm). Our results confirm that commercial broccoli seedlots can be naturally contaminated with pathogenic and aggressive A. brassicicola. We also provide evidence for potential presence of A. brassicicola isolates with reduced azoxystrobin-sensitivity in naturally infested commercial broccoli seedlots, which has never been reported before. Together, these findings may have implications in considerations for seed-health testing, seed treatments and greenhouse scouting to limit introduction of infested seedlots in commercial broccoli fields.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-01-24-0056-RE
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  4. Article: Evaluation of Stagonospora Nodorum Blotch Severity and

    Kaur, Navjot / Mehl, Hillary L / Langston, David / Haak, David C

    Phytopathology

    2024  Volume 114, Issue 1, Page(s) 258–268

    Abstract: Parastagonospora ... ...

    Abstract Parastagonospora nodorum
    MeSH term(s) Chromosome Mapping ; Quantitative Trait Loci ; Virginia ; Triticum/microbiology ; Plant Diseases/microbiology ; Genetic Variation ; Ascomycota
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208889-7
    ISSN 1943-7684 ; 0031-949X
    ISSN (online) 1943-7684
    ISSN 0031-949X
    DOI 10.1094/PHYTO-10-22-0392-R
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    Zs.B 698: Show issues Location:
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  5. Article: Arsenic Enrichment, Heavy Metal Pollution and Associated Health Hazards in the Holocene Alluvial Plains of Southeast Punjab, India

    Kaur, Navjot

    Soil & sediment contamination. 2022 Aug. 18, v. 31, no. 6

    2022  

    Abstract: The present research aimed to examine the soil quality and heavy metals pollution with special emphasis on arsenic (As) contamination around the Rupnagar District of Southeast Punjab, India. A Total of 17 soil samples (S1-S17) from depths of ~5-20 cm ... ...

    Abstract The present research aimed to examine the soil quality and heavy metals pollution with special emphasis on arsenic (As) contamination around the Rupnagar District of Southeast Punjab, India. A Total of 17 soil samples (S1-S17) from depths of ~5-20 cm were collected from cultivated land, barren land, riverbanks of Sutlej and Sirsa River, and from the vicinity of the industrial area in December 2018 covering an area of 1251 km². Our first-hand analysis highlights an alarming As enrichment in the sediments (up to 128 mg kg⁻¹). Sediment samples with near-neutral to alkaline pH were found to be enriched with toxic heavy metals including V, Co, Mn, Se, Cu and Fe. The results of statistical analysis including Principal Component Analysis (PCA), Pearson’s correlation and Positive Matrix Factorization Model (PMF) infers that majority of the heavy metal pollution is attributed to anthropogenic and industrial inputs with minor instincts of geogenic sources are also corroborated. The health risk assessment construes no potential health hazards on the inhabitants of the study area upon their exposure to heavy metals through different exposure pathways as all the values of hazard quotient (HQ) and hazard index (HI) were less than 1.
    Keywords agricultural land ; arsenic ; health effects assessments ; heavy metals ; models ; pH ; principal component analysis ; rivers ; sediment contamination ; sediments ; soil ; soil quality ; toxicity ; India
    Language English
    Dates of publication 2022-0818
    Size p. 738-755.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2017739-2
    ISSN 1549-7887 ; 1532-0383
    ISSN (online) 1549-7887
    ISSN 1532-0383
    DOI 10.1080/15320383.2021.2004996
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    Z 6090: Show issues

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  6. Article: Editorial: Oxytocin in brain health and disease: how can it exert such pleiotropic neuromodulatory effects?

    Talpo, Francesca / Kaur, Navjot / Biella, Gerardo

    Frontiers in molecular neuroscience

    2023  Volume 16, Page(s) 1215351

    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2452967-9
    ISSN 1662-5099
    ISSN 1662-5099
    DOI 10.3389/fnmol.2023.1215351
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  7. Article ; Online: Tuberculosis Diagnosis Using Isothermal Nucleic Acid Amplification in a Paper-and-Plastic Device.

    Kaur, Navjot / Toley, Bhushan J

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2621, Page(s) 295–306

    Abstract: Nucleic acid (DNA/RNA) amplification technologies are indispensable for applications like disease diagnostics, forensics, epidemiology, evolutionary biology, vaccine development, and therapeutics. While polymerase chain reaction (PCR) has deeply ... ...

    Abstract Nucleic acid (DNA/RNA) amplification technologies are indispensable for applications like disease diagnostics, forensics, epidemiology, evolutionary biology, vaccine development, and therapeutics. While polymerase chain reaction (PCR) has deeply penetrated the abovementioned fields and has been commercially successful, two major common disadvantages are exorbitant costs of associated equipment, which create concerning roadblocks in terms of affordability and accessibility. This work describes development of an inexpensive, portable, easy-to-use and deliverable-to-end-users, nucleic acid amplification technology for infectious disease diagnosis. The device uses loop-mediated isothermal amplification (LAMP) and cell phone-based fluorescence imaging to enable nucleic acid amplification and detection. A regular lab incubator and a custom-made low-cost imaging box are the only two additional equipment required for testing. Material cost for a 12-test zone device was $0.88, and cost of reagents per reaction was $0.43. First successful application of the device was demonstrated for tuberculosis diagnosis with clinical sensitivity of 100% and clinical specificity of 68.75% for testing of 30 clinical patient samples.
    MeSH term(s) Humans ; Plastics ; Tuberculosis/diagnosis ; DNA ; Polymerase Chain Reaction ; Nucleic Acids
    Chemical Substances Plastics ; DNA (9007-49-2) ; Nucleic Acids
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2950-5_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Enhanced functionality and shelf stability of

    Kaur, Sukhpreet / Aggarwal, Poonam / Kaur, Navjot

    Journal of food science and technology

    2022  Volume 59, Issue 12, Page(s) 4956–4968

    Abstract: ... Burfi, ... ...

    Abstract Burfi, an
    Language English
    Publishing date 2022-09-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 242498-8
    ISSN 0975-8402 ; 0022-1155
    ISSN (online) 0975-8402
    ISSN 0022-1155
    DOI 10.1007/s13197-022-05584-0
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  9. Article: Management of Lambda-Cyhalothrin Poisoning in a North Indian Healthcare Setup: A Rare Case.

    Sudan, Sourav / Kaur, Navjot / Taneja, Rishabh / Kaur, Navjot / Mehmi, Prachi

    Cureus

    2022  Volume 14, Issue 12, Page(s) e32746

    Abstract: Agricultural product (insecticides and pesticides) poisoning is common in the rural Indian setup, and in most cases, it occurs due to suicidal attempts rather than accidental intake. Furthermore, most cases of agrochemical poisoning are organophosphate ... ...

    Abstract Agricultural product (insecticides and pesticides) poisoning is common in the rural Indian setup, and in most cases, it occurs due to suicidal attempts rather than accidental intake. Furthermore, most cases of agrochemical poisoning are organophosphate poisoning rather than other less commonly used pesticides. Lambda-cyhalothrin is a less commonly used insecticide in India, and there have been a few instances in the literature where lambda-cyhalothrin poisoning and its subsequent management have been described. In this case report, we describe accidental lambda-cyhalothrin poisoning in a 26-year-old female and its management at our center.
    Language English
    Publishing date 2022-12-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.32746
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  10. Article ; Online: Development and characterisation of packing, microstructural, physico‐ and phytochemical attributes of potential functional jamun (Syzygium cumini L.)pomace powder for direct compression: high antioxidant nutraceutical tablets

    Kaur, Navjot / Aggarwal, Poonam

    International Journal of Food Science & Technology. 2023 Apr., v. 58, no. 4 p.2067-2076

    2023  

    Abstract: This study aimed at drying jamun pomace; a rich source of bioactive compounds and utilising it for development of phytonutrient and antioxidant‐rich nutraceutical tablets by mixing with ultrasonically extracted pomace extract. Packing, microstructural, ... ...

    Abstract This study aimed at drying jamun pomace; a rich source of bioactive compounds and utilising it for development of phytonutrient and antioxidant‐rich nutraceutical tablets by mixing with ultrasonically extracted pomace extract. Packing, microstructural, physico‐ and phytochemical properties of the powders produced by freeze drying, hot air drying were evaluated. Freeze‐dried powder showed better flowability, lower Hausner ratio and less hygroscopicity. Phytochemicals of freeze‐dried powder were approximately 15% higher than cabinet dried powder, further confirmed using Fourier transform infrared (FTIR) analysis, while producing more uniform particles as confirmed using SEM and particle size distribution. The freeze‐dried powder was further mixed with ultrasonically extracted pomace extract (using distilled water acidified with citric acid as solvent) in the ratio 1:1 (w/v) to increase phytonutritional profile and compressed to form tablets, which showed rapid disintegration and in vitro release of anthocyanins. Storage studies (at 25 ± 2 °C/50%–88% RH) revealed that the moisture and water activity significantly (P < 0.05) increased while approximately 76% phytochemicals and 81.20% antioxidant activities were retained at the end of four months. In the nutshell, the formulation of nutraceutical tablets with good bioavailability cannot only help in the effective utilisation of jamun waste but also provide nutraceutical product.
    Keywords Fourier transform infrared spectroscopy ; Syzygium cumini ; air ; anthocyanins ; antioxidants ; bioavailability ; citric acid ; dietary supplements ; food science ; freeze drying ; hygroscopicity ; particle size distribution ; phytonutrients ; pomace ; pomace extracts ; solvents ; wastes ; water activity
    Language English
    Dates of publication 2023-04
    Size p. 2067-2076.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 883561-5
    ISSN 0950-5423
    ISSN 0950-5423
    DOI 10.1111/ijfs.15933
    Database NAL-Catalogue (AGRICOLA)

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