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Article ; Online: Relative Frequency of Tuberous Breast Disorders among Candidates for Breast Augmentation Surgery

Mehdi Rasti-Ardakani / Sina Rasti

مجله دانشکده پزشکی اصفهان, Vol 40, Iss 674, Pp 392-

2022 Volume 397

Abstract: Background: Tuberous breast disorder (TBD), is manifested usually in small or asymmetric breasts after puberty, which makes patients candidates for breast augmentation surgery. Yet, its diagnosis may be difficult due to a wide variety of diagnostic ... ...

Abstract	Background: Tuberous breast disorder (TBD), is manifested usually in small or asymmetric breasts after puberty, which makes patients candidates for breast augmentation surgery. Yet, its diagnosis may be difficult due to a wide variety of diagnostic criteria and severity of the disorder. So, the aim of this study -which to our knowledge stands as the first epidemiologic study about TBD in Iran, is estimation of the relative frequency of TBD among candidates for breast augmentation surgery.Methods: In a descriptive cross-sectional study, profiles and real-size photograms of anteroposterior and lateral views of 732 referral candidates for breast augmentation surgery aged 18 years or older to clinics of two plastic surgeons in the city of [Isfahan] over a period of 9 years were enrolled. Relative frequency of TBD and its subtypes from I to III based on Grolleau et al. criteria, patients fulfilling at least one of the described features of the TBD, and breast asymmetry were estimated among the study population.Findings: Among the study population 78% experienced asymmetry and 28.9% were diagnosed with TBD with a distribution of 50.9%, 39.1%, and 9.9% in the groups I to III respectively. 73.9% of patients fulfilled at least one of the TBD features.Conclusion: Relative frequencies of 28.9% and 73.9% for TBD and its criteria respectively, show considerable prevalence among candidates for breast augmentation surgery.
Keywords	plastic surgery ; mammoplasty ; epidemiology ; breast implantation ; breast diseases ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	616
Language	Persian
Publishing date	2022-07-01T00:00:00Z
Publisher	Vesnu Publications
Document type	Article ; Online
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Article: Comparative Experimental Study of Dermal Stability: Acellular Dermal Matrix versus Crayopreserved Dermis.

Omranifard, Mahmood / Rasti Ardakani, Mehdi / Abdali, Hossein / Mortazavi, Pejman / Hoseini, Saeed / Hoghoughi, Mohammad Ali

World journal of plastic surgery

2021 Volume 10, Issue 2, Page(s) 82–88

Abstract: Background: Given the potential usefulness of Acellular Dermal Matrices (ADM) for wound healing, we aimed to evaluate the stability, histological characteristics, and effectiveness of ADM compared with cryopreserved dermis (CPD) in rat models.: ... ...

Abstract	Background: Given the potential usefulness of Acellular Dermal Matrices (ADM) for wound healing, we aimed to evaluate the stability, histological characteristics, and effectiveness of ADM compared with cryopreserved dermis (CPD) in rat models. Methods: This experimental study was conducted in the Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran, from January to March 2015. The prepared ADM and CPD were transplanted to the full-thickness skin defects on the back of Sprague-Dawley rats. Forty-five days after grafting, the tissues were harvested for histological examination. These two types of the dermis' quality and stability were compared with consideration of the following factors; inflammation, fibroblasts migration, vascularization, collagen formation, capsule formation, and microabscess formation. Results: From 19 selected rates, nine received CPD, and ten were treated with ADM. After transplantation, the mean (SD) weight of ADM and CPD grafts were 1.74 (0.07) and 1.45 (0.77), respectively ( Conclusion: ADM have a superior effect than CPD in the wound healing process. Both samples had a similar effect in capsule and microabscesses formation and higher costs of ADM preparation. According to the physicians' decision and evaluation of the process's cost-effectiveness, CPD could be appropriately used as an alternative to ADM.
Language	English
Publishing date	2021-06-29
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2781494-4
ISSN	2252-0724 ; 2228-7914
ISSN (online)	2252-0724
ISSN	2228-7914
DOI	10.29252/wjps.10.2.82
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Article: Tangibility of platelet-rich fibrin matrix for nasolabial folds.

Ardakani, Mehdi Rasti / Moein, Hamed Parsa / Beiraghdar, Mozhdeh

Advanced biomedical research

2016 Volume 5, Page(s) 197

Abstract: Background: Using autologous tissue is a simple process and ideal choice for augmentation of the soft facial tissue. In this regard, platelet-rich fibrin matrix (PRFM) is used for the correction of fine rhytids and nasolabial folds (NLFs) as well as ... ...

Abstract	Background: Using autologous tissue is a simple process and ideal choice for augmentation of the soft facial tissue. In this regard, platelet-rich fibrin matrix (PRFM) is used for the correction of fine rhytids and nasolabial folds (NLFs) as well as facial augmentation. This study tries to evaluate the tangibility of PRFM for facial augmentation. Materials and methods: In this study, 20 patients (20-45 years) were studied to examine the augmentation (4 patients were excluded). For each, 3cc of PRFM provided by using 35cc of autologous blood and injected through subdermal technique into NLFs. Thickness and volume of the tissue were measured before and 3 months after treatment by sonography. The collected data were analyzed through paired Results: The study included 16 women, with average of 39.43 ± 6.84 years (age range, 20-45 years). The thickness and the volume of subcutaneous tissue in NLFs before and after treatment show no significant difference on the right side rather than on the left side ( Conclusion: According to the results, the increased tissue volume by PRFM still persists after 3 months of treatment and its retention has been effective on the healing process.
Language	English
Publishing date	2016-12-27
Publishing country	India
Document type	Journal Article
ZDB-ID	2672524-1
ISSN	2277-9175
ISSN	2277-9175
DOI	10.4103/2277-9175.190987
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Outcomes of Lower Extremity Defects Reconstruction with Free Flaps

Mehrdad Adibparsa / Mehdi Rasti-Ardakani / Razieh Karimi

مجله دانشکده پزشکی اصفهان, Vol 35, Iss 439, Pp 883-

2017 Volume 889

Abstract: Background: The aims of soft-tissue reconstruction of lower leg defects are covering and repairing wounds, maintaining limb function, preventing amputation, and improving quality of life. Methods: In this cross-sectional study, 27 patients underwent soft- ...

Abstract	Background: The aims of soft-tissue reconstruction of lower leg defects are covering and repairing wounds, maintaining limb function, preventing amputation, and improving quality of life. Methods: In this cross-sectional study, 27 patients underwent soft-tissue reconstruction of lower extremities with free flaps were enrolled. The cause and the site of defects, free flap types, anastomosis types, survival rate, and complications were assessed. Findings: 27 patients with mean age of 31 years with large lower extremity defects with at least 2 months follow up were assessed. The sites of defects were middle and distal one-third of the legs (21 cases), foot and heel (4 cases), and knees (2 cases), and causes of defects were trauma (21 cases), and chronic wounds (2 cases). Used musculocutaneous free flaps were for latissimus dorsi (15 cases), rctus abdominis (8 cases), and gracilis (4 cases). 43 and 11 cases had end-to-end and end-to-site anastomosis, respectively. Survival rate was 88.9 percent and 3 flaps were failed due to thrombosis. Conclusion: Using free flaps with appropriate vascular pedicles is a reliable and effective method for reconstruction of lower leg large defects.
Keywords	Lower extremity ; Free flaps ; Wound healing ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	571
Language	Persian
Publishing date	2017-09-01T00:00:00Z
Publisher	Vesnu Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Effect of Systemic Antioxidant Allopurinol Therapy on Skin Flap Survival.

Rasti Ardakani, Mehdi / Al-Dam, Ahmed / Rashad, Ashkan / Shayesteh Moghadam, Ali

World journal of plastic surgery

2017 Volume 6, Issue 1, Page(s) 54–61

Abstract: Background: It has been reported that systemic administration of allopurinol improves cell survival. This study was aimed to evaluate effects of allopurinol on skin flaps in dogs.: Methods: Twenty dogs underwent one skin flap surgery with a 2-week ... ...

Abstract	Background: It has been reported that systemic administration of allopurinol improves cell survival. This study was aimed to evaluate effects of allopurinol on skin flaps in dogs. Methods: Twenty dogs underwent one skin flap surgery with a 2-week interval. The first procedure was performed according to the standard protocols. The second phase was started by a 1-week pretreatment with allopurinol. Length of the necrotic zone was measured and recorded daily. At each phase, flaps were removed and sent for histopathological study after 1 week observation. Results: Mean length of the necrotic zone in allopurinol treated skin flaps has been significantly less than normal flaps over all 7 days of observation ( Conclusion: It was demonstrated that systemic administration of allopurinol significantly improved skin flap survival.
Language	English
Publishing date	2017-02-28
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2781494-4
ISSN	2252-0724 ; 2228-7914
ISSN (online)	2252-0724
ISSN	2228-7914
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Article ; Online: Tangibility of platelet-rich fibrin matrix for nasolabial folds

Mehdi Rasti Ardakani / Hamed Parsa Moein / Mozhdeh Beiraghdar

Advanced Biomedical Research, Vol 5, Iss 1, Pp 197-

2016 Volume 197

Abstract	Background: Using autologous tissue is a simple process and ideal choice for augmentation of the soft facial tissue. In this regard, platelet-rich fibrin matrix (PRFM) is used for the correction of fine rhytids and nasolabial folds (NLFs) as well as facial augmentation. This study tries to evaluate the tangibility of PRFM for facial augmentation. Materials and Methods: In this study, 20 patients (20–45 years) were studied to examine the augmentation (4 patients were excluded). For each, 3cc of PRFM provided by using 35cc of autologous blood and injected through subdermal technique into NLFs. Thickness and volume of the tissue were measured before and 3 months after treatment by sonography. The collected data were analyzed through paired t-test and independent t- test by using SPSS version 19.0 (SPSS Inc., Chicago, IL, USA). Results: The study included 16 women, with average of 39.43 ± 6.84 years (age range, 20–45 years). The thickness and the volume of subcutaneous tissue in NLFs before and after treatment show no significant difference on the right side rather than on the left side (P > 0.05), but the thickness and the volume of the tissue on both sides after treatment shows significant increase rather than before treatment, so that this increase was significant statistically. This study shows that different right and left thickness was 0.54 ± 0.51 and 0.51 ± 0.38 (P ≤ 0.001). Further, different right and left volume was 0.25 ± 0.20 and 0.26 ± 0.22, respectively (P < 0.001). Conclusion: According to the results, the increased tissue volume by PRFM still persists after 3 months of treatment and its retention has been effective on the healing process.
Keywords	Facial augmentation ; nasolabial folds ; platelet-rich fibrin matrix ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: A comparison of outcome of medical and surgical treatment of migraine headache: In 1 year follow-up.

Omranifard, Mahmood / Abdali, Hossein / Ardakani, Mehdi Rasti / Talebianfar, Mohsen

Advanced biomedical research

2016 Volume 5, Page(s) 121

Abstract: Background: This study was designed to compare the efficacy of the medical treatment versus the surgical treatment approach to decompression of trigger point nerves in patients with migraine headaches.: Materials and methods: Fifty volunteers were ... ...

Abstract	Background: This study was designed to compare the efficacy of the medical treatment versus the surgical treatment approach to decompression of trigger point nerves in patients with migraine headaches. Materials and methods: Fifty volunteers were randomly assigned to the medical treatment group (n = 25) or the surgical treatment group (n = 25) after examination by the team neurologist to ensure a diagnosis of migraine headache. All patients received botulinum toxin type A to confirm the trigger sites. The surgical treatment group underwent surgical deactivation of the trigger site(s). The medical treatment group underwent prophylactic pharmacologic interventions by the neurologist. Pretreatment and 12-month posttreatment migraine headache frequency, duration, and intensity were analyzed and compared to determine the success of the treatments. Results: Nineteen of the 25 patients (76%) in the surgical treatment group and 10 of the 25 patients (40%) in the medical treatment group experienced a successful outcome (at least a 50% decrease in migraine frequency, duration, or intensity) after 1 year from surgery. Surgical treatment had a significantly higher success rate than medical treatment (P < 0.001). Nine patients (36%) in the surgical treatment group and one patient (4%) in the medical treatment group experienced cessation of migraine headaches. The elimination rate was significantly higher in the surgical treatment group than in the medical treatment group (P < 0.001). Conclusions: Based on the 1-year follow-up data, there is strong evidence that surgical manipulation of one or more migraine trigger sites can successfully eliminate or reduce the frequency, duration, and intensity of migraine headaches in a lasting manner.
Language	English
Publishing date	2016-07-29
Publishing country	India
Document type	Journal Article
ZDB-ID	2672524-1
ISSN	2277-9175
ISSN	2277-9175
DOI	10.4103/2277-9175.186994
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Article: Comparison of the effects of spreader graft and overlapping lateral crural technique on rhinoplasty by rhinomanometry.

Omranifard, Mahmoud / Abdali, Hosein / Rasti Ardakani, Mehdi / Ahmadnia, Amiryousef

World journal of plastic surgery

2014 Volume 2, Issue 2, Page(s) 99–103

Abstract: Background: Nasal valve collapse and especially internal nasal valve insufficiency is a common cause of nasal airway obstruction. This study compares the effects of spreader graft and overlapping lateral crural technique on rhinoplasty by rhinomanometry. ...

Abstract	Background: Nasal valve collapse and especially internal nasal valve insufficiency is a common cause of nasal airway obstruction. This study compares the effects of spreader graft and overlapping lateral crural technique on rhinoplasty by rhinomanometry. Methods: Fifty patients were randomly assigned into two groups and underwent spreader graft or overlapping lateral crural technique. Objective assessment was performed by clinical examination and rhinomanometry before and after rhinoplasty. Results: Nasal obstruction had no significant difference before and after rhinoplasty and no significant difference was observed between surgical techniques. Right, left and total nasal flow and resistance were different before and after surgery but were not significant. Base of the nose was not significantly different between two groups, but nasal projection was 2 mm in the the group who underwent overlapping lateral crura technique and the difference was statistically significant. Our study showed that both overlapping lateral crura and spreader graft technique were beneficial in rhinoplasty and they could provide enough internal nasal valve support. The overlapping lateral crura was an appropriate surgical technique for tip projection in comparison to spreader graft. Conclusion: The overlapping lateral crura technique was shown to be a better surgical way for tip projection in comparison to spreader graft.
Language	English
Publishing date	2014-02-12
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2781494-4
ISSN	2252-0724 ; 2228-7914
ISSN (online)	2252-0724
ISSN	2228-7914
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Article: Introduction of a potent single-donor fibrin glue for vascular anastomosis: An animal study.

Ardakani, Mehdi Rasti / Hormozi, Abdoljalil Kalantar / Ardakani, Jalal Rasti / Davarpanahjazi, Amir Hossein / Moghadam, Ali Shayesteh

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

2013 Volume 17, Issue 5, Page(s) 461–465

Abstract: Background: Vascular anastomosis is considered as a difficult surgical procedure. Although different alternative methods have been tried to tackle these difficulties, none were found to be successful. Commercial fibrin glue has recently been used for ... ...

Abstract	Background: Vascular anastomosis is considered as a difficult surgical procedure. Although different alternative methods have been tried to tackle these difficulties, none were found to be successful. Commercial fibrin glue has recently been used for vascular anastomosis. However, it did not gain popularity due to some limitations such as low tensile strength, rapid removal by the immune system, and risk of transmission of blood-borne viral infections. In this article, we presented a novel method for producing single-donor human fibrin glue and determined its success rate for vascular anastomosis in an animal model. Materials and methods: [corrected] In this study, 3 mL of single-donor fibrin sealant was prepared from 150 mL of whole blood containing 50-70 mg/mL of fibrinogen. The study was performed on 10 dogs and 5 cats. After transection of the carotid artery, both ends were anastomosed by means of 3-4 sutures (Prolene 8-0). The suture line was then sealed with one layer of the new fibrin sealant. After 3-8 weeks, the site of anastomosis was evaluated angiographically and morphologically for healing and possible complications such as thrombosis or aneurysm. Results: In evaluations 3 weeks after the surgery, all arterial anastomoses were patent in dogs, but some degree of subintimal hyperplasia was noted. After 8 weeks, all anastomoses were patent and the degree of subintimal hyperplasia was decreased. In cats on the other hand, after 4 weeks, all anastomoses were patent and subintimal hyperplasia was absent. Conclusions: Single-donor fibrin glue was a quite reliable and practical alternative to minimize suturing and therefore operative time in our animal model. This sealant can easily be obtained from the patient's whole blood. Its application in humans would require further studies.
Language	English
Publishing date	2013-04-19
Publishing country	India
Document type	Journal Article
ZDB-ID	2513029-8
ISSN	1735-7136 ; 1735-1995
ISSN (online)	1735-7136
ISSN	1735-1995
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Article ; Online: A comparison of outcome of medical and surgical treatment of migraine headache

Mahmood Omranifard / Hossein Abdali / Mehdi Rasti Ardakani / Mohsen Talebianfar

Advanced Biomedical Research, Vol 5, Iss 1, Pp 121-

In 1 year follow-up

2016 Volume 121

Abstract: Background: This study was designed to compare the efficacy of the medical treatment versus the surgical treatment approach to decompression of trigger point nerves in patients with migraine headaches. Materials and Methods: Fifty volunteers were ... ...

Abstract	Background: This study was designed to compare the efficacy of the medical treatment versus the surgical treatment approach to decompression of trigger point nerves in patients with migraine headaches. Materials and Methods: Fifty volunteers were randomly assigned to the medical treatment group (n = 25) or the surgical treatment group (n = 25) after examination by the team neurologist to ensure a diagnosis of migraine headache. All patients received botulinum toxin type A to confirm the trigger sites. The surgical treatment group underwent surgical deactivation of the trigger site(s). The medical treatment group underwent prophylactic pharmacologic interventions by the neurologist. Pretreatment and 12-month posttreatment migraine headache frequency, duration, and intensity were analyzed and compared to determine the success of the treatments. Results: Nineteen of the 25 patients (76%) in the surgical treatment group and 10 of the 25 patients (40%) in the medical treatment group experienced a successful outcome (at least a 50% decrease in migraine frequency, duration, or intensity) after 1 year from surgery. Surgical treatment had a significantly higher success rate than medical treatment (P < 0.001). Nine patients (36%) in the surgical treatment group and one patient (4%) in the medical treatment group experienced cessation of migraine headaches. The elimination rate was significantly higher in the surgical treatment group than in the medical treatment group (P < 0.001). Conclusions: Based on the 1-year follow-up data, there is strong evidence that surgical manipulation of one or more migraine trigger sites can successfully eliminate or reduce the frequency, duration, and intensity of migraine headaches in a lasting manner.
Keywords	Medical treatment ; migraine headache ; migraine headache index ; surgical treatment ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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