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  1. Article ; Online: Guidongnins I-J: Two New 6,7-

    Zou, Juan / Ye, Jianghai / Zhao, Chenliang / Zhang, Jingjie / Liu, Yahua / Pan, Lutai / He, Kang / Zhang, Hongjie

    International journal of molecular sciences

    2023  Volume 24, Issue 17

    Abstract: ... Two ... ...

    Abstract Two undescribed
    MeSH term(s) Diterpenes, Kaurane/pharmacology ; Isodon ; Diterpenes/pharmacology ; Carbon ; Cell Line
    Chemical Substances Diterpenes, Kaurane ; Diterpenes ; Carbon (7440-44-0)
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241713451
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  2. Article ; Online: Magnetic double-J stent: Evaluation of tolerance and impact on quality of life compared to traditional double-J stent.

    Diranzo-Garcia, M / Pardo-Duarte, P / Álvarez-Barrera, A / Juan-Escudero, J U / Beltrán-Puig, M / Monzó-Cataluña, A / Rechi-Sierra, K / Sánchez-Ballester, F / Garcia-Ibáñez, J / López-Alcina, E

    Actas urologicas espanolas

    2021  Volume 45, Issue 5, Page(s) 366–372

    Abstract: ... from the use of a magnetic double-J stent (Black Star®) and compare them to those presented in patients ... with a traditional double-J stent (OptiMed®).: Material and methods: We conducted a comparative, prospective ... randomized study in 46 patients who underwent ureterorenoscopy with double-J stent placement between August ...

    Abstract Introduction: The placement of a ureteral stent is one of the most widely performed procedures in urology. It can have a negative impact on the patients' quality of life, requiring a cystoscopy for its removal. The objective of this study is to evaluate the symptoms and impact on quality of life derived from the use of a magnetic double-J stent (Black Star®) and compare them to those presented in patients with a traditional double-J stent (OptiMed®).
    Material and methods: We conducted a comparative, prospective, randomized study in 46 patients who underwent ureterorenoscopy with double-J stent placement between August 2019 and June 2020. Of all patients included, 23 had a traditional double-J stent placed (group A) and 23 had a magnetic double-J stent (group B) placed. We evaluated the results of the Ureteral Stent Symptom Questionnaire (USSQ) in both groups, assessed the technical difficulty related to stent removal and the pain during the procedure using the Visual Analogue Scale (VAS). We also reviewed the need for medical attention due to problems related to the stent or after its removal.
    Results: There were no statistically significant differences between groups regarding the answers in the USSQ and the complications related to the use of the stent. Group B showed less pain (1.52 vs. 4, VAS, p = 0.001) and less difficulty during removal (1.61 vs. 3, p < 0.001) associated with a shorter procedure duration (11.65 min vs. 22.17 min p < 0.001).
    Conclusions: The tolerance shown by the use of magnetic double-J is comparable to the tolerance of traditional stent, since it does not cause an increase in urinary symptoms nor worsens the quality of life of patients during its use.
    MeSH term(s) Humans ; Magnetic Phenomena ; Prospective Studies ; Quality of Life ; Stents ; Ureter/surgery
    Language Spanish
    Publishing date 2021-05-14
    Publishing country Spain
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2021.04.004
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  3. Article ; Online: Corrigendum to "Sex differences on multikinase inhibitors toxicity in patients with advanced gastroenteropancreatic neuroendocrine tumours" [Eur J Cancer 188 (2023) 39-48].

    Hernando, Jorge / Roca-Herrera, Maria / García-Álvarez, Alejandro / Raymond, Eric / Ruszniewski, Philippe / Kulke, Matthew H / Grande, Enrique / Carbonero, Rocío García / Castellano, Daniel / Salazar, Ramón / Ibrahim, Toni / Teule, Alex / Alonso, Vicente / Fazio, Nicola / Valle, Juan W / Tafuto, Salvatore / Carmona, Ana / Navarro, Victor / Capdevila, Jaume

    European journal of cancer (Oxford, England : 1990)

    2024  Volume 203, Page(s) 114061

    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Published Erratum
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2024.114061
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    Zs.A 456: Show issues Location:
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    Zs.MO 583: Show issues

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  4. Article ; Online: Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism.

    Bao, Luyao / Hu, Juan / Zhan, Bowen / Chi, Mingzhe / Li, Zhengyang / Wang, Sen / Shan, Chan / Zhao, Zhaozhao / Guo, Yanchao / Ding, Xiaoming / Ji, Chaoneng / Tao, Shengce / Ni, Ting / Zhang, Xuelian / Zhao, Guoping / Li, Jixi

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 2280

    Abstract: Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA ... degradosome, plays an essential role in global mRNA decay. Emerging evidence showed that the RNase J ... of Mycobacterium tuberculosis (Mtb-RNase J) could be an excellent target for treating Mtb infection. Here, crystal structures ...

    Abstract Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay. Emerging evidence showed that the RNase J of Mycobacterium tuberculosis (Mtb-RNase J) could be an excellent target for treating Mtb infection. Here, crystal structures of Mtb-RNase J in apo-state and complex with the single-strand RNA reveal the conformational change upon RNA binding and hydrolysis. Mtb-RNase J forms an active homodimer through the interactions between the β-CASP and the β-lactamase domain. Knockout of RNase J slows the growth rate and changes the colony morphologies and cell length in Mycobacterium smegmatis, which is restored by RNase J complementation. Finally, RNA-seq analysis shows that the knockout strain significantly changes the expression levels of 49 genes in metabolic pathways. Thus, our current study explores the structural basis of Mtb-RNase J and might provide a promising candidate in pharmacological treatment for tuberculosis.
    MeSH term(s) Ribonucleases/metabolism ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/metabolism ; RNA/metabolism ; Ribonuclease, Pancreatic/metabolism ; Hydrolysis
    Chemical Substances Ribonucleases (EC 3.1.-) ; RNA (63231-63-0) ; Ribonuclease, Pancreatic (EC 3.1.27.5)
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-38045-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Novel ELISA for the Quantification of Serum Levels of 2 Glycosylated Variants of Apolipoprotein J: Biomarkers for Myocardial Ischemia.

    Fernández Encinas, Lola / Lluch, Nuria / Wu, Alan H B / Kaski, Juan Carlos / Badimon, Lina / Cubedo, Judit

    The journal of applied laboratory medicine

    2023  Volume 8, Issue 5, Page(s) 917–930

    Abstract: Background: Previous studies have pointed out a potential role of ApoJ-Glyc as a biomarker of cardiac ischemia. The aim of this study was to validate the analytical performance of 2 novel ELISAs against 2 different glycosylated ApoJ variants, ApoJ- ... ...

    Abstract Background: Previous studies have pointed out a potential role of ApoJ-Glyc as a biomarker of cardiac ischemia. The aim of this study was to validate the analytical performance of 2 novel ELISAs against 2 different glycosylated ApoJ variants, ApoJ-GlycA2 and ApoJ-GlycA6.
    Methods: The analytical measuring range, limit of blank (LoB), lower limit of quantification (LoQ), precision, accuracy, recovery, cross-reactivity, and stability were evaluated in serum samples.
    Results: The analytical measuring range was 500-16 000 ng/mL for ApoJ-GlycA2 and 125-4000 ng/mL for ApoJ-GlycA6, with a LoB of 455 ng/mL and 121 ng/mL for ApoJ-GlycA2 and ApoJ-GlycA6, respectively. The LoQ was 500 ng/mL for ApoJ-GlycA2 and 125 ng/mL for ApoJ-GlycA6. The assay performance fulfills the acceptance criteria established in the European Medicines Agency Guideline on bioanalytical method validation. Specifically, the calibration range variability is <15% for ApoJ-GlycA2 and ApoJ-GlycA6; the accuracy is <15% for ApoJ-GlycA2 and ApoJ-GlycA6; the between- and within-run precision is <15% for ApoJ-GlycA6 and ≤20% for ApoJ-GlycA2; and the total allowable error is <30% for ApoJ-GlycA2 and ApoJ-GlycA6. Cross-reactivity studies revealed the absence of cross-reactivity with endogenous components of the matrix (using ApoJ-depleted serum), with nonglycosylated ApoJ and with transferrin (as a high abundant N-glycosylated serum protein). Both ApoJ-GlycA2 and ApoJ-GlycA6 measurements were stable after storage of serum samples at -80°C for 24 months.
    Conclusions: The newly developed ELISAs to quantify ApoJ-GlycA2 and ApoJ-GlycA6 serum levels showed an acceptable analytical performance according to European Medicines Agency guidelines on bioanalytical method validation in terms of precision, accuracy, recovery, cross-reactivity, and stability.
    MeSH term(s) Humans ; Clusterin ; Myocardial Ischemia/diagnosis ; Coronary Artery Disease ; Biomarkers ; Enzyme-Linked Immunosorbent Assay
    Chemical Substances Clusterin ; Biomarkers
    Language English
    Publishing date 2023-07-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1093/jalm/jfad034
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  6. Article ; Online: Aloina scindulosa M.J.Cano, J.A.Jiménez & M.T.Gallego (Pottiaceae), a new moss species from Argentina

    Cano, María J. / Jiménez, Juan A. / Martinez, Monica / Teresa Gallego, M. / Suárez, Guillermo M.

    Journal of Bryology. 2023 Apr. 03, v. 45, no. 2 p.105-112

    2023  

    Abstract: ... scindulosa M.J.Cano, J.A.Jiménez & M.T.Gallego is described and illustrated as a new moss species from four ...

    Abstract During field studies in Argentina, we collected a specimen of Aloina Kindb. that did not match any of the known species of the genus. Here we present our arguments for recognising this moss as a new species. The morphology of the new taxon was compared with that of the species of Aloina presently recognised. In addition, most of the type material of the taxa attributed to this genus in the world has been studied. Aloina scindulosa M.J.Cano, J.A.Jiménez & M.T.Gallego is described and illustrated as a new moss species from four localities in the Monte Desert area of Argentina. It is distinct from all other members of the genus in the combination of its lingulate leaves with unbordered margins, rectangular and slightly sheathing leaf bases, leaves ending in a long, hyaline, papillose hair-point near the leaf apex, the costa scarcely differentiated, in cross-section with no stereids, and the upper and middle laminal cells and costal surface dorsally prorate in the upper midleaf. Possible confusion with other species of the genus is discussed. A key to the South American species of Aloina is provided.
    Keywords Pottiaceae ; bryology ; deserts ; leaves ; mosses and liverworts ; new species ; Argentina ; Distribution ; mosses ; South America ; taxonomy
    Language English
    Dates of publication 2023-0403
    Size p. 105-112.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2080324-2
    ISSN 1743-2820 ; 0373-6687
    ISSN (online) 1743-2820
    ISSN 0373-6687
    DOI 10.1080/03736687.2023.2218726
    Database NAL-Catalogue (AGRICOLA)

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  7. Book: Carlos J. Finlay

    López Sánchez, José / Finlay, Carlos Juan

    his life and his work

    1999  

    Title translation Finlay,El hombre y la verdad científíca
    Author's details José López Sánchez.[Transl.: Carmen Gónzalez Díaz de Villegas ]
    Language Spanish
    Size 560 S.
    Publisher Martí
    Publishing place La Habana
    Publishing country Cuba
    Document type Book
    HBZ-ID HT014513403
    ISBN 959-09-0138-7 ; 978-959-09-0138-6
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2005 A 4119 order for loan Magazin

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  8. Article ; Online: J-filter: An experiment to simplify and isolate specific signals in

    Góñez, Karen V / García, Juan Suárez / Sardina, F Javier / Pazos, Yolanda / Saá, Ángela / Martín Pastor, Manuel

    Magnetic resonance in chemistry : MRC

    2023  Volume 61, Issue 11, Page(s) 615–622

    Abstract: One-dimensional selective NMR experiments relying on a J-filter element are proposed to isolate ...

    Abstract One-dimensional selective NMR experiments relying on a J-filter element are proposed to isolate specific signals in crowded
    Language English
    Publishing date 2023-09-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1475029-6
    ISSN 1097-458X ; 0749-1581
    ISSN (online) 1097-458X
    ISSN 0749-1581
    DOI 10.1002/mrc.5396
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  9. Article ; Online: Taxonomic notes on some neglected doryctine wasps (Hymenoptera: Braconidae) from Argentina described by J. Brthes and E. Blanchard.

    Martnez, Juan Jos / Diez, Fernando

    Zootaxa

    2024  Volume 5406, Issue 1, Page(s) 190–200

    Abstract: The type specimens of Austrodolops eremitae Blanchard, Doryctes ridiaschinae Brthes, and Hormiopius ptericoptophagus Blanchard were studied and reclassified according to the current classification of the subfamily Doryctinae. The monotypic genera ... ...

    Abstract The type specimens of Austrodolops eremitae Blanchard, Doryctes ridiaschinae Brthes, and Hormiopius ptericoptophagus Blanchard were studied and reclassified according to the current classification of the subfamily Doryctinae. The monotypic genera Austrodolops Blanchard and Hormiopius Blanchard are treated as junior synonyms of Allorhogas Gahan (syn. nov.) and Heterospilus Haliday (syn. nov.) respectively. Examination of the gall associated species D. ridiaschinae shows that it belongs in the genus Allorhogas. All species are redescribed and illustrated and the following new combinations are proposed: Allorhogas eremitae (Blanchard) (comb. nov.), Allorhogas ridiaschinae (Brthes) (comb. nov.) and Heterospilus ptericoptophagus (Blanchard) (comb. nov.). Lectotypes are designated for all studied species and the genus Doryctes is excluded from the currently known Argentine fauna.
    MeSH term(s) Animals ; Wasps ; Hymenoptera ; Argentina
    Language English
    Publishing date 2024-02-02
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5406.1.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Corrigendum to "Arsenic exposure and pulmonary function decline: Potential mediating role of TRAIL in chronic obstructive pulmonary disease patients" [J. Trace Elem. Med. Biol. 83 (2024) 127415].

    Liu, Ying / Zhu, Feng-Min / Xu, Juan / Deng, You-Peng / Sun, Jing / He, Qi-Yuan / Cheng, Zhen-Yu / Tang, Min-Min / Yang, Jin / Fu, Lin / Zhao, Hui

    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

    2024  Volume 83, Page(s) 127418

    Language English
    Publishing date 2024-02-27
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1236267-0
    ISSN 1878-3252 ; 1611-602X ; 0946-672X
    ISSN (online) 1878-3252 ; 1611-602X
    ISSN 0946-672X
    DOI 10.1016/j.jtemb.2024.127418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2279: Show issues Location:
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