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Article ; Online: Outpatient Check-In Using an Online Portal.

Immens, Maikel / Verstraete, Esther / Klein Bleumink, Gerdy / Pisters, Ron

Telemedicine reports

2023 Volume 4, Issue 1, Page(s) 336–342

Abstract: Background: Despite ongoing digital and technological developments, incorporation of new developments in outpatient care tends to be slow. Regarding an increasing demand for outpatient care, digitalization of health care carries the potential of a much ... ...

Abstract	Background: Despite ongoing digital and technological developments, incorporation of new developments in outpatient care tends to be slow. Regarding an increasing demand for outpatient care, digitalization of health care carries the potential of a much needed more efficient and patient-oriented system. Objective: To optimize classic face-to-face outpatient clinic follow-up consultations and evaluate the added value of an upfront digital consult preparation (DCP). Methods: A cross-sectional observational study was conducted at Rijnstate Hospital (Arnhem, the Netherlands) among all consecutive patients, 18 years or older, who visited the Cardiology (in June 2021) or Neurology (in September 2021) outpatient clinic. All received a DCP survey before their scheduled outpatient clinic appointment, containing three questions regarding their upcoming visit. In addition, the involved health care providers were approached by using a questionnaire to share their experience regarding the DCP. Data concerning the experience of patients and health care providers was anonymous and gathered using Qualtrics.com. Results: All 25 involved health care providers (12 cardiologists, 13 neurologists) provided feedback. According to the health care providers DCP decreased the workload and improved theirs and patients' preparation. In total, 785 of 1626 (48.3%) patients filled-in the DCP before their appointment within a predetermined period. Only 4% of the patients wanted to change or cancel the consultation. A total of 122 of the 300 (40.1%) patients approached, filled-in a questionnaire to reflect on the DCP. Patients experienced DCP as an improvement of consultation, more time-efficient, increasing patients' and health care providers' preparation, increasing a feeling of acknowledgement and improving co-decision on type of consultation. The DCP did not attribute to co-deciding on treatment. Conclusion: DCP was perceived as an improvement of the standard outpatient care by both health care providers and patients with automated integration into the electronic patient record being of key importance.
Language	English
Publishing date	2023-10-26
Publishing country	United States
Document type	Journal Article
ISSN	2692-4366
ISSN (online)	2692-4366
DOI	10.1089/tmr.2023.0026
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Article ; Online: Antistolling zinvol bij kortdurend atriumfibrilleren?

Seelig, Jaap / Pisters, Ron / Alings, A M W Marco / Hemels, Martin E W

Nederlands tijdschrift voor geneeskunde

2023 Volume 167

Abstract: In patients with short episodes of clinical, non-triggered AF is the evidence for long-term anticoagulation based on the CHA2DS2-VASc score strong. In situations where a temporary trigger for AF is observed (e.g. after surgery or an infection), or when ... ...

Title translation	Anticoagulation useful in short episodes of atrial fibrillation?
Abstract	In patients with short episodes of clinical, non-triggered AF is the evidence for long-term anticoagulation based on the CHA2DS2-VASc score strong. In situations where a temporary trigger for AF is observed (e.g. after surgery or an infection), or when AF is only detected on a cardiac implantable electronic device (CIED) or smartwatch, the evidence for anticoagulation is less well established. Despite the short duration of the AF episode(s), both patients with subclinical or triggered AF are often at an inherently increased risk of stroke or thromboembolism. In some of these cases long-term anticoagulation can be considered, especially when other cardiovascular risk factors are present. Important considerations when deciding to start with long-term anticoagulation are the individually estimated risk of thrombosis and bleeding, the implementation of shared decision making, and the optimization of the overall cardiovascular risk management.
MeSH term(s)	Humans ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/complications ; Risk Factors ; Anticoagulants/adverse effects ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Hemorrhage/chemically induced ; Risk Assessment
Chemical Substances	Anticoagulants
Language	Dutch
Publishing date	2023-02-08
Publishing country	Netherlands
Document type	English Abstract ; Journal Article
ZDB-ID	82073-8
ISSN	1876-8784 ; 0028-2162
ISSN (online)	1876-8784
ISSN	0028-2162
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Article: Design of the Dutch multicentre study on opportunistic screening of geriatric patients for atrial fibrillation using a smartphone PPG app: the Dutch-GERAF study.

Zwart, Lennaert A R / Spruit, Jocelyn R / Hemels, Martin E W / de Groot, Joris R / Pisters, Ron / Riezebos, Robert K / Jansen, René W M M

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

2024 Volume 32, Issue 5, Page(s) 200–205

Abstract: Background: Screening of high-risk patients is advocated to achieve early detection and treatment of clinical atrial fibrillation (AF). The Dutch-GERAF study will address two major issues. Firstly, the effectiveness and feasibility of an opportunistic ... ...

Abstract	Background: Screening of high-risk patients is advocated to achieve early detection and treatment of clinical atrial fibrillation (AF). The Dutch-GERAF study will address two major issues. Firstly, the effectiveness and feasibility of an opportunistic screening strategy for clinical AF will be assessed in frail older patients and, secondly, observational data will be gathered regarding the efficacy and safety of oral anticoagulation (OAC). Methods: This is a multicentre study on opportunistic screening of geriatric patients for clinical AF using a smartphone photoplethysmography (PPG) application. Inclusion criteria are age ≥ 65 years and the ability to perform at least three PPG recordings within 6 months. Exclusion criteria are the presence of a cardiac implantable device, advanced dementia or a severe tremor. The PPG application records patients' pulse at their fingertip and determines the likelihood of clinical AF. If clinical AF is suspected after a positive PPG recording, a confirmatory electrocardiogram is performed. Patients undergo a comprehensive geriatric assessment and a frailty index is calculated. Risk scores for major bleeding (MB) are applied. Standard laboratory testing and additional laboratory analyses are performed to determine the ABC-bleeding risk score. Follow-up data will be collected at 6 months, 12 months and 3 years on the incidence of AF, MB, hospitalisation, stroke, progression of cognitive disorders and mortality. Discussion: The Dutch-GERAF study will focus on frail older patients, who are underrepresented in randomised clinical trials. It will provide insight into the effectiveness of screening for clinical AF and the efficacy and safety of OAC in this high-risk population. Trial registration: NCT05337202.
Language	English
Publishing date	2024-04-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2211468-3
ISSN	1876-6250 ; 1568-5888 ; 0929-7456
ISSN (online)	1876-6250
ISSN	1568-5888 ; 0929-7456
DOI	10.1007/s12471-024-01868-6
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Article ; Online: Comparison of Supraflex Cruz 60 μm Versus Ultimaster Tansei 80 μm Stent Struts in High Bleeding Risk PCI Patients: Study design and Rational of Compare 60/80 HBR trial.

Paradies, Valeria / Maurina, Matteo / Tonino, Pim / Hofma, Sjoerd H / Vos, Jeroen / van Kuijk, Jan-Peter / Oemrawsingh, Rohit M / Mafragi, Amar Al / Spano, Fabrizio / Pisters, Ron / Polad, Jawed / Ijsselmuiden, Sander / Cambero, Maribel Madeira / Smits, Pieter C

The American journal of cardiology

2023 Volume 206, Page(s) 230–237

Abstract: Up to 45% of patients who underwent percutaneous coronary intervention (PCI) may have a high bleeding risk (HBR), depending on the bleeding risk definition. ...

Abstract	Up to 45% of patients who underwent percutaneous coronary intervention (PCI) may have a high bleeding risk (HBR), depending on the bleeding risk definition.
Language	English
Publishing date	2023-09-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.08.046
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Article ; Online: Screening over 100 000 patients in 39 general practices in the Netherlands for anticoagulation underprescription in atrial fibrillation: a descriptive, cross-sectional study.

Voorhout, Leonard / Pisters, Ron / Geurts, Constants H P H / Oostindjer, Andrew / van Doorn, Sander / Rila, Harrie / Fuijkschot, Wessel W / Verheugt, Freek / Hemels, Martin E W

BMJ open

2023 Volume 13, Issue 8, Page(s) e072655

Abstract: Objectives: To investigate the underprescription of oral anticoagulation (OAC) in individual atrial fibrillation (AF) patients in primary care.: Setting: Screening of patient records in 39 participating general practitioners (GPs) across the ... ...

Abstract	Objectives: To investigate the underprescription of oral anticoagulation (OAC) in individual atrial fibrillation (AF) patients in primary care. Setting: Screening of patient records in 39 participating general practitioners (GPs) across the Netherlands. Participants: We screened 101 207 patient records identifying 2375 non-valvular AF patients. Methods: Using electronic patient files, we were able to screen the entire GP population for AF, CHA Results: We found a mean CHA Conclusions: In this large Dutch study among GPs, we observed 9.8% underprescription of OAC in AF patients. In 76% of the AF patients lacking a prescription for OAC, no documentation for deviating from the guidelines was found. Only in a minority of cases detection of OAC underprescription lead to OAC initiation.
MeSH term(s)	Female ; Male ; Humans ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Cross-Sectional Studies ; Netherlands ; General Practice ; Anticoagulants/therapeutic use
Chemical Substances	Anticoagulants
Language	English
Publishing date	2023-08-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-072655
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Article ; Online: Major adverse cardiac events after elective infrarenal endovascular aortic aneurysm repair.

Diender, Eline / Vermeulen, Jenske J M / Pisters, Ron / van Schaik, Paul M / Reijnen, Michel M P J / Holewijn, Suzanne

Journal of vascular surgery

2022 Volume 76, Issue 6, Page(s) 1527–1536.e3

Abstract: Objective: There is a significant cardiac morbidity and mortality after endovascular aneurysm repair (EVAR). However, information about long-term risk of cardiac events after EVAR and potential predictors is lacking. Therefore, the aim of this study was ...

Abstract	Objective: There is a significant cardiac morbidity and mortality after endovascular aneurysm repair (EVAR). However, information about long-term risk of cardiac events after EVAR and potential predictors is lacking. Therefore, the aim of this study was to determine incidence and predictors of major adverse cardiac events (MACE) at 1 and 5 years after elective EVAR for infrarenal abdominal aortic aneurysms. Methods: Baseline, perioperative, and postoperative information of 320 patients was evaluated. The primary outcome was the incidence of MACE after EVAR, which was defined as acute coronary syndrome, unstable angina pectoris, de novo atrial fibrillation, hospitalization for heart failure, mitral valve insufficiency, revascularization (including percutaneous coronary intervention and coronary artery bypass grafting), as well as cardiovascular and noncardiovascular death. Kaplan-Meier analyses were performed to determine incidences of MACE, MACE excluding noncardiovascular death and cardiac events by excluding noncardiovascular and vascular death from MACE. Predictors of MACE were identified using univariate and multivariate binary regression analysis. Results: Through 1 and 5 years of follow-up after EVAR, freedom from MACE was 89.4% (standard error [SE], 0.018) and 59.8% (SE, 0.033), freedom from MACE excluding noncardiovascular death was 94.7% (SE, 0.013) and 77.5% (SE, 0.030) and freedom from cardiac events was 96.0% (SE, 0.011) and 79.1% (SE, 0.030), respectively. Predictors for MACE within 1 year were American Society of Anesthesiologists (ASA) score of III or IV (odds ratio [OR], 3.17; 95% confidence interval [CI], 1.52-6.59) and larger abdominal aortic diameter (OR, 1.04; 95% CI, 1.01-1.08). A history of atrial fibrillation (OR, 0.14; 95% CI, 0.03-0.60) was a negative predictor factor. Predictors for MACE through 5 years were a history of heart failure (OR, 4.10; 95% CI 1.36-12.32) and valvular heart disease (OR, 2.31; 95% CI, 0.97-5.51), American Society of Anesthesiologists score of 3 or 4 (OR, 1.66; 95% CI, 0.96-2.88), and older age (OR, 1.04; 95% CI, 1.01-1.08). Conclusions: MACE is a common complication during the first 5 years after elective EVAR. Cardiac diseases at baseline are strong predictors for long-term MACE and potentially helpful in optimizing future postoperative long-term follow-up.
MeSH term(s)	Humans ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Aortic Aneurysm, Abdominal/complications ; Blood Vessel Prosthesis Implantation/adverse effects ; Endovascular Procedures/adverse effects ; Atrial Fibrillation/complications ; Retrospective Studies ; Risk Factors ; Treatment Outcome ; Time Factors ; Heart Failure/etiology ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Risk Assessment
Language	English
Publishing date	2022-06-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2022.05.018
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Article ; Online: Can a Single Measurement of Apixaban Levels Identify Patients at Risk of Overexposure? A Prospective Cohort Study.

de Vries, Tim A C / Hirsh, Jack / Bhagirath, Vinai C / Ginsberg, Jeffrey S / Pisters, Ron / Hemels, Martin E W / de Groot, Joris R / Eikelboom, John W / Chan, Noel C

TH open : companion journal to thrombosis and haemostasis

2022 Volume 6, Issue 1, Page(s) e10–e17

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2022-01-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2901738-5
ISSN	2512-9465 ; 2567-3459
ISSN (online)	2512-9465
ISSN	2567-3459
DOI	10.1055/s-0041-1740492
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Article ; Online: Unequal prescription of anticoagulants among females and males with atrial fibrillation and similar stroke risk: Should we omit sex category from the CHA

Seelig, Jaap / Chu, Gordon / Trinks-Roerdink, Emmy M / Pisters, Ron / de Vries, Tim A C / Ten Cate, Hugo / Geersing, Geert-Jan / Rutten, Frans H / Huisman, Menno V / Hemels, Martin E W

Heart rhythm

2022 Volume 19, Issue 5, Page(s) 860–861

MeSH term(s)	Administration, Oral ; Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Female ; Humans ; Male ; Prescriptions ; Risk Assessment ; Risk Factors ; Stroke/etiology ; Stroke/prevention & control
Chemical Substances	Anticoagulants
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2229357-7
ISSN	1556-3871 ; 1547-5271
ISSN (online)	1556-3871
ISSN	1547-5271
DOI	10.1016/j.hrthm.2022.01.014
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Article ; Online: Periprocedural antithrombotic management of patients undergoing ablation for atrial fibrillation: what we currently do...and what should we do?

Pisters, Ron / Lip, Gregory Y H

The Canadian journal of cardiology

2013 Volume 29, Issue 2, Page(s) 139–141

MeSH term(s)	Anticoagulants/therapeutic use ; Atrial Fibrillation/surgery ; Catheter Ablation/methods ; Humans ; Risk Assessment/methods ; Thromboembolism/prevention & control
Chemical Substances	Anticoagulants
Language	English
Publishing date	2013-02
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	632813-1
ISSN	1916-7075 ; 0828-282X
ISSN (online)	1916-7075
ISSN	0828-282X
DOI	10.1016/j.cjca.2012.05.016
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Article ; Online: WITHDRAWN: Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm.

Lip, Gregory Y H / Wrigley, Benjamin J / Pisters, Ron

The Cochrane database of systematic reviews

2016 , Issue 5, Page(s) CD003333

MeSH term(s)	Anticoagulants/therapeutic use ; Heart Failure/complications ; Heart Failure/mortality ; Humans ; Platelet Aggregation Inhibitors/therapeutic use ; Randomized Controlled Trials as Topic ; Thromboembolism/drug therapy ; Thromboembolism/etiology
Chemical Substances	Anticoagulants ; Platelet Aggregation Inhibitors
Language	English
Publishing date	2016-05-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
ISSN	1469-493X
ISSN (online)	1469-493X
DOI	10.1002/14651858.CD003333.pub2
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