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Article ; Online: Breastfeeding success and perceived social support in lactating women with a history of COVID 19 infection: a prospective cohort study.

Moini, Ashraf / Heidari, Fatemeh / Eftekhariyazdi, Mitra / Pirjani, Reihaneh / Ghaemi, Marjan / Eshraghi, Nasim / Rabiei, Maryam

International breastfeeding journal

2023 Volume 18, Issue 1, Page(s) 65

Abstract: Background: Given the limited availability of research on the association between COVID-19 infection and breastfeeding success, the primary objective of this study is to conduct a comprehensive evaluation of this relationship.: Methods: This ... ...

Abstract	Background: Given the limited availability of research on the association between COVID-19 infection and breastfeeding success, the primary objective of this study is to conduct a comprehensive evaluation of this relationship. Methods: This prospective cohort study included 260 women who were on the postnatal ward of an academic hospital affiliated with Tehran University of Medical Sciences during the COVID-19 pandemic (between March and August 2021). Among these women, 130 had tested positive for COVID-19 in pregnancy, while the remaining 130 were considered healthy. The study aimed to assess various factors, including sociodemographic characteristics and the results of four validated questionnaires: The Bristol Breastfeeding Questionnaire, The Multidimensional of Perceived Social Support (MPSS), The Breastfeeding Self-Efficacy Scale (BSES), and The Postpartum Partner Support Scale (PPSS). These questionnaires were administered to each participant to gather relevant data. After eight weeks, a telephone follow-up was carried out to assess the success of breastfeeding. The evaluation focused on determining if exclusive breastfeeding was maintained or not. Data was collected by questioning mothers about their infants' feeding habits in the past 24 h. Exclusive breastfeeding refers to the exclusive use of breast milk without the introduction of other liquids or solid foods. Results: Women with a previous COVID-19 infection (case group) had a lower mean infant gestational age (P < 0.001) and a higher prevalence of cesarean section (P = 0.001) compared to the control group. The proportion of women who exclusively breastfed was higher in the control group (98.5%) than in women with a history of COVID-19 infection (89.2%) (P = 0.011). Furthermore, the case group reported lower scores in perceived social support and the Breastfeeding Self-Efficacy Scale, in contrast to the control group. Notably, there was a significant correlation between breastfeeding success and women's breastfeeding self-efficacy score. Conclusions: The findings of this study offer valuable insights for healthcare professionals, enabling them to promote early initiation of breastfeeding in mothers with a history of COVID-19 infection, while ensuring necessary precautions are taken.
MeSH term(s)	Infant ; Humans ; Female ; Pregnancy ; Breast Feeding ; Prospective Studies ; Cesarean Section ; Lactation ; Pandemics ; COVID-19 ; Iran/epidemiology ; Social Support
Language	English
Publishing date	2023-12-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2227239-2
ISSN	1746-4358 ; 1746-4358
ISSN (online)	1746-4358
ISSN	1746-4358
DOI	10.1186/s13006-023-00601-0
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Article ; Online: COVID‑19 vaccine hesitancy among pregnant women and their reported reasons for vaccine refusal - A prospective study in Tehran, Iran.

Moini, Ashraf / Rabiei, Maryam / Pirjani, Reihaneh / Abiri, Amene / Maleki-Hajiagha, Arezoo

Vaccine

2023 Volume 41, Issue 8, Page(s) 1490–1495

Abstract: Objective: Evaluation of covid‑19 vaccine hesitancy among pregnant women and their reported reasons for vaccine refusal.: Methods: This prospective study was performed in Arash women's Hospital, Tehran, Iran, between December 1, 2021 and January 1, ... ...

Abstract	Objective: Evaluation of covid‑19 vaccine hesitancy among pregnant women and their reported reasons for vaccine refusal. Methods: This prospective study was performed in Arash women's Hospital, Tehran, Iran, between December 1, 2021 and January 1, 2022. All pregnant women who were attended to prenatal care unit were considered eligible for inclusion. A validated questionnaire was used for data gathering. Written informed consent was obtained from all participants. Results: Finally, 477 pregnant women were recruited and were divided into two groups according the status of vaccine acceptance (237 accepted and 240 women refused vaccination). The mean age of accepted participants was higher (31.65 ± 5.69 vs 30.39 ± 5.5; P = 0.01). There was a significant statistical difference between the groups regarding education level. Access to internet and social media were also significantly different between the two groups (94.8% in accepted vs 86.6% in refused group; P = 0.002). There was more rate of severe COVID-19 infection in friends or relatives of accepted group (50% vs 38%). we did not find any statistically significant differences in obstetric characteristics and the rate of obstetric complications between the two groups. The most common reasons reported by participants for vaccine refusal, was fear of vaccination side effects on the fetus (86.5%), and the less common reported reasons were husband's disagreement (9.7%), use of traditional medicine (5.6%), religious beliefs (3.7%), and information obtained from social media (2.8%). After advices from medical staff, most of these mothers (86.5%) still refused vaccination. Conclusion: Based on the results of the present study,rate of COVID-19 vaccine hesitancy was about 50% and its most common reported reason was fear of probable side effects of vaccine on the fetus.
MeSH term(s)	Female ; Humans ; Pregnancy ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Iran/epidemiology ; Pregnant Women ; Prospective Studies ; Vaccination/adverse effects ; Vaccination Refusal
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-01-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2023.01.022
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Article ; Online: Co-culture of human cryopreserved fragmented ovarian tissue with theca progenitor cells derived from theca stem cells.

Dalman, Azam / Adib, Samane / Amorim, Christiani A / Pirjani, Reihaneh / Totonchi, Mehdi / Valojerdi, Mojtaba Rezazadeh

Journal of assisted reproduction and genetics

2023 Volume 40, Issue 7, Page(s) 1611–1622

Abstract: Purpose: Despite the significant advances in the in vitro development of human primordial follicles, it is still a challenging approach with great potential for improvements. Therefore, the present study aimed to investigate the effect of a feeder layer ...

Abstract	Purpose: Despite the significant advances in the in vitro development of human primordial follicles, it is still a challenging approach with great potential for improvements. Therefore, the present study aimed to investigate the effect of a feeder layer of human theca progenitor cells (hTPCs) on the development of primordial follicles embedded in human ovarian tissue. Methods: Fragments of frozen-thawed ovarian tissue were activated using the vanadate-derivative dipotassium bisperoxo (5-hydroxy-pyridine-2-carboxylic) oxovanadate (V) and kit ligand for 24 h. Then, the specimens were divided into the co-culture and mono-culture groups and were cultured with and without a hTPC feeder layer for 6 days, respectively. Afterward, the follicles were counted and classified, and the hormone levels and expression levels of apoptosis- and folliculogenesis-related genes were assessed. Results: Both culture groups showed significant follicle growth (P < 0.05). However, the co-culture group had a significantly higher number of growing follicles compared to the other group (P < 0.05). Moreover, the expression levels of ZP1, ZP2, ZP3, BMP-7, AMH, and GDF9 were significantly higher in the co-culture group compared to the other group (P < 0.05), while the expression levels of P53 and CASP3 were significantly lower (P < 0.05). Also, the concentrations of estradiol, progesterone, testosterone, and androstenedione were significantly higher in the co-culture group compared to the other group (P < 0.05). Conclusion: The present study results provided novel evidence on the direct role of hTPCs in the growth and development of human primordial follicles. However, there is a need for future studies to illustrate the underlying mechanisms. Schematic summary of the results. According to our results, the expression of ZP1, ZP2, ZP3, and GDF9 in the oocytes, AMH in the granulosa cells, and BMP4 in the theca cells of the co-culture group were significantly higher than those of the mono-culture and non-culture groups, while the expression of apoptotic genes (BAX, CASP3, and P53) was significantly lower. Moreover, the co-culture group showed significantly increased levels of estradiol, progesterone, testosterone, and androstenedione in its culture media compared to the mono-culture groups.
MeSH term(s)	Female ; Humans ; Theca Cells/metabolism ; Caspase 3 ; Progesterone/metabolism ; Androstenedione/metabolism ; Androstenedione/pharmacology ; Coculture Techniques ; Tumor Suppressor Protein p53/genetics ; Granulosa Cells/metabolism ; Estradiol/metabolism ; Testosterone/metabolism
Chemical Substances	Caspase 3 (EC 3.4.22.-) ; Progesterone (4G7DS2Q64Y) ; Androstenedione (409J2J96VR) ; Tumor Suppressor Protein p53 ; Estradiol (4TI98Z838E) ; Testosterone (3XMK78S47O)
Language	English
Publishing date	2023-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1112577-9
ISSN	1573-7330 ; 1058-0468
ISSN (online)	1573-7330
ISSN	1058-0468
DOI	10.1007/s10815-023-02799-8
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Article ; Online: A comparison of the effects of Two suture materials on isthmocele formation: A cohort study.

Hosseini, Reihaneh / Mansoorli, Somayeh / Pirjani, Reihaneh / Eslamian, Laleh / Rabiee, Maryam

Journal of gynecology obstetrics and human reproduction

2020 Volume 50, Issue 4, Page(s) 101933

Abstract: Objective: Cesarean scar defects (CSD) are a problem that may lead to complications and excessive cost. The optimal way to suture the uterus is a matter of debate. The aim of this study was to evaluate the effect of two suture materials on cesarean scar ...

Abstract	Objective: Cesarean scar defects (CSD) are a problem that may lead to complications and excessive cost. The optimal way to suture the uterus is a matter of debate. The aim of this study was to evaluate the effect of two suture materials on cesarean scar niches. Study design: This was a cohort study that allocated women into two groups: uterotomy closure with vicryl or catgut sutures. Transvaginal ultrasound (TVUS) was performed six months after the cesarean section (CS) to assess the scar. Results: Totally, 250 patients enrolled in this study. After six months, 20 (18.2 %) patients in the catgut suture group and 13 (9.3 %) patients in the vicryl group had isthmocele according to their sonography reports. The prevalence of isthmocele was higher in the catgut group (p = 0.03). The residual myometrial thickness was greater in the vicryl group (4.98 cm ± 2.18) compared to the catgut suture group (3.70 cm ± 1.50; p = 0.001). The prevalence of postoperative gynecological sequelae such as postmenstrual spotting and pain were similar between the two groups. Conclusion: Vicryl sutures were associated with a lower risk of CSD formation in comparison with catgut sutures.
MeSH term(s)	Abdominal Wound Closure Techniques ; Adult ; Catgut/adverse effects ; Cesarean Section/adverse effects ; Cicatrix/complications ; Cicatrix/diagnostic imaging ; Female ; Humans ; Polyglactin 910/adverse effects ; Postoperative Complications/diagnostic imaging ; Prospective Studies ; Sutures/adverse effects ; Time Factors ; Uterus/surgery ; Young Adult
Chemical Substances	Polyglactin 910 (34346-01-5)
Language	English
Publishing date	2020-10-14
Publishing country	France
Document type	Clinical Trial ; Comparative Study ; Journal Article ; Multicenter Study
ISSN	2468-7847
ISSN (online)	2468-7847
DOI	10.1016/j.jogoh.2020.101933
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Article ; Online: Breastfeeding success and perceived social support in lactating women with a history of COVID 19 infection

Ashraf Moini / Fatemeh Heidari / Mitra Eftekhariyazdi / Reihaneh Pirjani / Marjan Ghaemi / Nasim Eshraghi / Maryam Rabiei

International Breastfeeding Journal, Vol 18, Iss 1, Pp 1-

a prospective cohort study

2023 Volume 6

Abstract: Abstract Background Given the limited availability of research on the association between COVID-19 infection and breastfeeding success, the primary objective of this study is to conduct a comprehensive evaluation of this relationship. Methods This ... ...

Abstract	Abstract Background Given the limited availability of research on the association between COVID-19 infection and breastfeeding success, the primary objective of this study is to conduct a comprehensive evaluation of this relationship. Methods This prospective cohort study included 260 women who were on the postnatal ward of an academic hospital affiliated with Tehran University of Medical Sciences during the COVID-19 pandemic (between March and August 2021). Among these women, 130 had tested positive for COVID-19 in pregnancy, while the remaining 130 were considered healthy. The study aimed to assess various factors, including sociodemographic characteristics and the results of four validated questionnaires: The Bristol Breastfeeding Questionnaire, The Multidimensional of Perceived Social Support (MPSS), The Breastfeeding Self-Efficacy Scale (BSES), and The Postpartum Partner Support Scale (PPSS). These questionnaires were administered to each participant to gather relevant data. After eight weeks, a telephone follow-up was carried out to assess the success of breastfeeding. The evaluation focused on determining if exclusive breastfeeding was maintained or not. Data was collected by questioning mothers about their infants’ feeding habits in the past 24 h. Exclusive breastfeeding refers to the exclusive use of breast milk without the introduction of other liquids or solid foods. Results Women with a previous COVID-19 infection (case group) had a lower mean infant gestational age (P < 0.001) and a higher prevalence of cesarean section (P = 0.001) compared to the control group. The proportion of women who exclusively breastfed was higher in the control group (98.5%) than in women with a history of COVID-19 infection (89.2%) (P = 0.011). Furthermore, the case group reported lower scores in perceived social support and the Breastfeeding Self-Efficacy Scale, in contrast to the control group. Notably, there was a significant correlation between breastfeeding success and women’s breastfeeding self-efficacy score. ...
Keywords	COVID 19 ; Pregnancy ; Breastfeeding ; Pediatrics ; RJ1-570 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article: An Overview on Guidelines on COVID-19 Virus and Natural and Assisted Reproductive Techniques Pregnancies.

Pirjani, Reihaneh / Rabiei, Maryam / Abiri, Ameneh / Moini, Ashraf

International journal of fertility & sterility

2020 Volume 14, Issue 3, Page(s) 264–271

Abstract: In this article, we reviewed and compared some of COVID-19 and pregnancy guidelines; this can be useful for pregnant women including those with a history of infertility specially those undergone assisted reproductive techniques (ART). The general advice ... ...

Abstract	In this article, we reviewed and compared some of COVID-19 and pregnancy guidelines; this can be useful for pregnant women including those with a history of infertility specially those undergone assisted reproductive techniques (ART). The general advice given for prenatal care is to reduce face-to-face visits. All women who refer for prenatal visits should be evaluated for signs of the infection at the time of entry. The triage of suspected women should be done separately from other patients. Outpatient monitoring with a 14-day selfquarantine can be considered for asymptomatic infected women and for those with mild symptoms. Inpatient management criteria include moderate to severe symptoms and the target level of oxygen saturation is 92 to 95% in different guidelines. In the presence of fever, it is important to conduct a thorough examination of other causes of the fever. It is important to monitor fluid intake and output, maintain fluid and electrolyte balance and prevent fluid overload. Thromboembolic prophylaxis is recommended. Corticosteroid administration is based on obstetrics indications, while in critical ill cases, it should be based on multi-disciplinary teams (MDT) decision. A positive COVID-19 result in the absence of other obstetrics causes, cannot be considered an indication for delivery in mild and asymptomatic cases. In critically ill pregnant women, an individualized decision should be made about delivery time by the MDT. General anesthetic should be avoided unless inevitable for standard procedures such as intubation is an aerosol-generating procedure (AGP). There is agreement on the point that babies born to infected mothers, even if isolated from the mother at birth, should be considered a close contact of the mother and tested for COVID-19 and separated from other neonates. Breastfeeding is encouraged and hand hygiene and face mask during feeding are highly recommended by all guidelines.
Keywords	covid19
Language	English
Publishing date	2020-10-12
Publishing country	Iran
Document type	Letter
ZDB-ID	2570865-X
ISSN	2008-0778 ; 2008-076X
ISSN (online)	2008-0778
ISSN	2008-076X
DOI	10.22074/IJFS.2020.46230
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Article ; Online: The effect of hydroxychloroquine on pregnancy outcomes in patients with unexplained recurrent pregnancy loss: a placebo-controlled study "pilot study".

Moini, Ashraf / Sepidarkish, Mahdi / Dehpour, Ahmad Reza / Rabiei, Maryam / Abiri, Ameneh / Pirjani, Reihaneh

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

2022 Volume 42, Issue 8, Page(s) 3471–3476

Abstract: This double-blind placebo-controlled study investigated the effect of hydroxychloroquine on pregnancy outcomes in people with unexplained recurrent pregnancy loss (URPL). The inclusion criteria included gestational age ≤6 weeks and a history of at least ... ...

Abstract	This double-blind placebo-controlled study investigated the effect of hydroxychloroquine on pregnancy outcomes in people with unexplained recurrent pregnancy loss (URPL). The inclusion criteria included gestational age ≤6 weeks and a history of at least two miscarriages. The exclusion criteria included any known cause for previous abortions or a history of any chronic diseases. Participants were given 200 mg hydroxychloroquine or placebo twice a day until gestational week 20. Twenty-nine women were enrolled. There was no statistically significant difference between the two groups in terms of age, BMI, gravidity, previous abortion, relative married couple, and infertility. Miscarriage occurred in five women including one in the hydroxychloroquine group (7.69%) and four women in the placebo group (28.57%) (OR: 2.36, 95% PL CI:1.07, 8.93). However, after adjusting for potential confounders, there was no significant difference between the two groups (aOR: 2.96, 95%CI: 0.91, 10.02).IMPACT STATEMENT
MeSH term(s)	Pregnancy ; Humans ; Female ; Infant ; Pregnancy Outcome ; Hydroxychloroquine/adverse effects ; Treatment Outcome ; Abortion, Habitual/therapy ; Double-Blind Method
Chemical Substances	Hydroxychloroquine (4QWG6N8QKH)
Language	English
Publishing date	2022-11-21
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	604639-3
ISSN	1364-6893 ; 0144-3615
ISSN (online)	1364-6893
ISSN	0144-3615
DOI	10.1080/01443615.2022.2141615
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Article ; Online: An Overview on Guidelines on COVID-19 Virus and Natural and Assisted Reproductive Techniques Pregnancies

Reihaneh Pirjani / Maryam Rabiei / Ameneh Abiri / Ashraf Moini

International Journal of Fertility and Sterility, Vol 14, Iss 3, Pp 264-

2020 Volume 271

Abstract: In this article, we reviewed and compareed some of COVID-19 and pregnancy guidelines, which is useful for pregnant women including who have a history of infertility specially who have undergone assisted reproductive techniques. The general advice given ... ...

Abstract	In this article, we reviewed and compareed some of COVID-19 and pregnancy guidelines, which is useful for pregnant women including who have a history of infertility specially who have undergone assisted reproductive techniques. The general advice given for prenatal care is to reduce face-to-face visits. All women who refer for prenatal visits should be evaluated for signs of the infection at the time of entry. The triage of suspected women should be separate from other patients. Outpatient monitoring with a 14-day self-quarantine can be considered for asymptomatic infected women and also for women with mild symptoms. Inpatient management criteria include moderate to severe symptoms and the target level of oxygen saturation is considered between 92% and 95% in different guidelines. In the presence of fever, it is important to conduct a thorough examination of the other causes of the fever. It is important to monitor fluid intake and output, maintain fluid and electrolyte balance and prevent fluid overload. Thromboembolic prophylaxis is recommended. Corticosteroid administration in based on obstetrics indications, unless in severe critical ill cases which should be based on MDT decision. A positive COVID-19 result which lacks other obstetrics causes can not be considered as indicationfor delivery in mild and asymptomatic cases. In critically ill pregnant women, an individualized decision should be made about delivery time by the MDT. General anesthetic should be avoided unless inevitable for standard procedures such as intubation is an aerosol-generating procedure. There is agreement that babies born to infected mothers, even if isolated from the mother at birth, should be considered a close contact of the mother and tested for COVID-19 and also separated from other neonates. Breastfeeding is encouraged and hand hygiene and face mask during feeding is highly recommended by all guidelines.
Keywords	corona virus ; covid-19 ; guideline ; pregnancy ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2020-10-01T00:00:00Z
Publisher	Royan Institute (ACECR), Tehran
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An Overview on Guidelines on COVID-19 Virus and Natural and Assisted Reproductive Techniques Pregnancies

Reihaneh Pirjani / Maryam Rabiei / Ameneh Abiri / Ashraf Moini

International Journal of Fertility and Sterility, Vol 14, Iss 3, Pp 264-

2020 Volume 271

Abstract	In this article, we reviewed and compareed some of COVID-19 and pregnancy guidelines, which is useful for pregnant women including who have a history of infertility specially who have undergone assisted reproductive techniques. The general advice given for prenatal care is to reduce face-to-face visits. All women who refer for prenatal visits should be evaluated for signs of the infection at the time of entry. The triage of suspected women should be separate from other patients. Outpatient monitoring with a 14-day self-quarantine can be considered for asymptomatic infected women and also for women with mild symptoms. Inpatient management criteria include moderate to severe symptoms and the target level of oxygen saturation is considered between 92% and 95% in different guidelines. In the presence of fever, it is important to conduct a thorough examination of the other causes of the fever. It is important to monitor fluid intake and output, maintain fluid and electrolyte balance and prevent fluid overload. Thromboembolic prophylaxis is recommended. Corticosteroid administration in based on obstetrics indications, unless in severe critical ill cases which should be based on MDT decision. A positive COVID-19 result which lacks other obstetrics causes can not be considered as indicationfor delivery in mild and asymptomatic cases. In critically ill pregnant women, an individualized decision should be made about delivery time by the MDT. General anesthetic should be avoided unless inevitable for standard procedures such as intubation is an aerosol-generating procedure. There is agreement that babies born to infected mothers, even if isolated from the mother at birth, should be considered a close contact of the mother and tested for COVID-19 and also separated from other neonates. Breastfeeding is encouraged and hand hygiene and face mask during feeding is highly recommended by all guidelines.
Keywords	corona virus ; covid-19 ; guideline ; pregnancy ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2020-10-01T00:00:00Z
Publisher	Royan Institute (ACECR), Tehran
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Differential expression of

Amin-Beidokhti, Mona / Sadeghi, Hossein / Pirjani, Reihaneh / Gachkar, Latif / Gholami, Milad / Mirfakhraie, Reza

Journal of the Turkish German Gynecological Association

2021 Volume 22, Issue 4, Page(s) 273–278

Abstract: Objective: Preeclampsia (PE) is a pregnancy hypertensive disorder that affects both maternal and fetal health. Many studies have investigated possible mechanisms in the pathogenesis of PE although the role of the placenta is undeniable. Evaluation of ... ...

Abstract	Objective: Preeclampsia (PE) is a pregnancy hypertensive disorder that affects both maternal and fetal health. Many studies have investigated possible mechanisms in the pathogenesis of PE although the role of the placenta is undeniable. Evaluation of placental-specific microRNAs may provide additional data about the pathogenic mechanism of PE. This study compared the expression levels of Material and methods: One hundred tissues were obtained from fetal and maternal sides of the placenta of PE patients and healthy controls. Expression analysis was performed using quantitative real-time polymerase chain reaction. Results: Hsa-miR-517a/b Conclusion: These results demonstrate a differential expression of
Language	English
Publishing date	2021-12-06
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2425806-4
ISSN	1309-0380 ; 1303-9695 ; 1309-0399
ISSN (online)	1309-0380 ; 1303-9695
ISSN	1309-0399
DOI	10.4274/jtgga.galenos.2021.2021.0062
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