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  1. Article ; Online: Treatment with direct oral anticoagulants (DOACs) and secondary prophylaxis in patients affected by multiple episodes of superficial venous thrombosis.

    Laganà, Alessandro / Sorella, Silvia / Fucci, Ludovica / Genoese, Angelo / Chistolini, Antonio

    European journal of internal medicine

    2024  Volume 122, Page(s) 135–138

    MeSH term(s) Humans ; Venous Thrombosis/drug therapy ; Venous Thrombosis/prevention & control ; Anticoagulants/therapeutic use ; Secondary Prevention ; Venous Thromboembolism/drug therapy ; Administration, Oral
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2024-01-19
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.01.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2608: Show issues Location:
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  2. Article ; Online: Fostamatinib combined with TPO-RAs or steroids as a bridge to monotherapy or as time-limited continuous treatment in relapsed chronic ITP: A single-centre case series.

    Passucci, Mauro / Laganà, Alessandro / Donzelli, Livia / Masucci, Chiara / Genoese, Angelo / Chistolini, Antonio / Baldacci, Erminia / Santoro, Cristina

    British journal of haematology

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Letter
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.19450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Thromboembolic events following mRNA vaccines for COVID 19: a case series.

    Serrao, Alessandra / Agrippino, Roberta / Brescini, Mattia / Mormile, Rosaria / Chistolini, Antonio

    Journal of thrombosis and thrombolysis

    2022  Volume 53, Issue 4, Page(s) 971–973

    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Thromboembolism/etiology ; Vaccines, Synthetic/adverse effects ; mRNA Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines, Synthetic ; mRNA Vaccines
    Language English
    Publishing date 2022-02-03
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1230645-9
    ISSN 1573-742X ; 0929-5305
    ISSN (online) 1573-742X
    ISSN 0929-5305
    DOI 10.1007/s11239-021-02627-9
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    Zs.A 4352: Show issues Location:
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  4. Article ; Online: Immune thrombocytopenia management during COVID-19 pandemic: An Italian monocentric experience.

    Lapietra, Gianfranco / Ferretti, Antonietta / Baldacci, Erminia / Chistolini, Antonio / Santoro, Cristina

    EJHaem

    2022  Volume 3, Issue 2, Page(s) 453–456

    Abstract: Over the last 2 years, different cases of immune thrombocytopenia (ITP) in patients affected by SARS-CoV2 have been reported. The management of SARS-CoV2 in subjects with simultaneous or previous ITP can be challenging because of the great involvement of ...

    Abstract Over the last 2 years, different cases of immune thrombocytopenia (ITP) in patients affected by SARS-CoV2 have been reported. The management of SARS-CoV2 in subjects with simultaneous or previous ITP can be challenging because of the great involvement of the haemostatic system in this viral infection. In this report, we describe the management and outcome of patients with newly diagnosed (ND), chronic and previous ITP, infected by COVID-19, referred to the Haematology Institute of University Hospital Policlinico Umberto I in Rome. Steroids + immunoglobulins for ND or relapsed ITP and continuation of home therapy for chronic ITP are advised, although further knowledge is required.
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Journal Article
    ISSN 2688-6146
    ISSN (online) 2688-6146
    DOI 10.1002/jha2.406
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  5. Article: Secondary Prophylaxis of Venous Thromboembolism (VTE) with Low Dose Apixaban or Rivaroxaban: Results from a Patient Population with More than 2 Years of Median Follow-up.

    Laganà, Alessandro / Assanto, Giovanni Manfredi / Masucci, Chiara / Passucci, Mauro / Donzelli, Livia / Serrao, Alessandra / Baldacci, Erminia / Santoro, Cristina / Chistolini, Antonio

    Mediterranean journal of hematology and infectious diseases

    2024  Volume 16, Issue 1, Page(s) e2024020

    Abstract: Background: Direct oral anticoagulants (DOACs) are widely used for the treatment and secondary prophylaxis of venous thromboembolism (VTE). Nowadays, DOACs represent the gold standard for long-term anticoagulation, with low-intensity DOACs ... ...

    Abstract Background: Direct oral anticoagulants (DOACs) are widely used for the treatment and secondary prophylaxis of venous thromboembolism (VTE). Nowadays, DOACs represent the gold standard for long-term anticoagulation, with low-intensity DOACs administration becoming increasingly used worldwide in such scenario. Albeit low-intensity apixaban and rivaroxaban are approved for clinical usage as secondary VTE prophylaxis, there are few literature data regarding their efficacy and safety with a long follow-up.
    Objectives: The aim of our study was to evaluate the efficacy and safety of low-dose DOACs for VTE secondary prophylaxis in patients at high risk of VTE recurrence.
    Methods: We retrospectively evaluated patients who required long-term anticoagulant secondary prophylaxis to prevent recurrent VTE, treated with apixaban 2.5 mg BID or rivaroxaban 10 mg daily with a follow-up ≥ 12 months.
    Results: The examined patients were 323. The median low-dose DOAC administration time was 25.40 months (IQR 13.93-45.90). Twelve (3.7%) VTE recurrences were observed; 21 bleeding events were registered (6.5%), including one episode of Major bleeding (MB) (0.3%), 8 Clinically relevant nonmajor bleeding (CRNMB) (2.5%) and 12 minor bleeding (3.7%). No statistically significant difference in the rate of VTE recurrence and/or bleeding events emerged between the rivaroxaban and apixaban groups. Patients included in the study for multiple episodes of VTE presented a significantly higher risk of a new VTE recurrence during low-intensity DOAC.
    Conclusions: Our data suggest that low-dose DOACs may be effective and safe in secondary VTE prophylaxis in patients at high risk of VTE recurrence; however, attention might be needed in their choice in such a scenario for patients who experienced multiple episodes of VTE.
    Language English
    Publishing date 2024-03-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2674750-9
    ISSN 2035-3006
    ISSN 2035-3006
    DOI 10.4084/MJHID.2024.020
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  6. Article ; Online: Post-filter thromboembolic prophylaxis in vena cava filter carriers.

    Serrao, Alessandra / Fiori, Luciano / Chistolini, Antonio

    Phlebology

    2020  Volume 36, Issue 1, Page(s) 79–80

    MeSH term(s) Device Removal ; Humans ; Pulmonary Embolism/prevention & control ; Thromboembolism/etiology ; Thromboembolism/prevention & control ; Vena Cava Filters ; Vena Cava, Inferior ; Venous Thrombosis
    Language English
    Publishing date 2020-08-04
    Publishing country England
    Document type Letter
    ZDB-ID 645172-x
    ISSN 1758-1125 ; 0268-3555
    ISSN (online) 1758-1125
    ISSN 0268-3555
    DOI 10.1177/0268355520938580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2538: Show issues Location:
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  7. Article ; Online: "Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients-30 months follow-up": Comment from Serrao et al.

    Serrao, Alessandra / Assanto, Giovanni Manfredi / Malfona, Francesco / Chavez Orellana, Gabriela / Chistolini, Antonio

    Journal of thrombosis and haemostasis : JTH

    2022  Volume 20, Issue 8, Page(s) 1935–1937

    MeSH term(s) Anticoagulants/adverse effects ; Follow-Up Studies ; Humans ; Neoplasms/complications ; Neoplasms/drug therapy ; Pyrazoles ; Pyridones/adverse effects ; Venous Thromboembolism/drug therapy
    Chemical Substances Anticoagulants ; Pyrazoles ; Pyridones ; apixaban (3Z9Y7UWC1J)
    Language English
    Publishing date 2022-07-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.15775
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    Zs.A 5805: Show issues Location:
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    Zs.MO 295: Show issues

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  8. Article ; Online: The treatment of upper extremities deep vein thrombosis related to thoracic outlet syndrome with direct oral anticoagulants.

    Fiori, Luciano / Serrao, Alessandra / Ferretti, Antonietta / Chistolini, Antonio

    Phlebology

    2020  Volume 36, Issue 4, Page(s) 329–330

    Abstract: Venous thoracic outlet syndrome (VTOS) is a manifestation of venous symptoms that occurs when the subclavian vein is compressed and it may present clinically with acute venous thrombosis of the axillo-subclavian vein. Evidence for the optimal approach to ...

    Abstract Venous thoracic outlet syndrome (VTOS) is a manifestation of venous symptoms that occurs when the subclavian vein is compressed and it may present clinically with acute venous thrombosis of the axillo-subclavian vein. Evidence for the optimal approach to the management of this condition is sparse and actually anticoagulation alone is not considered an option. Herein we reported our experience with direct oral anticoagulants in patients with upper extremities deep vein thrombosis, due to VTOS, who refused endovascular approach or surgery.
    MeSH term(s) Anticoagulants/adverse effects ; Humans ; Subclavian Vein/diagnostic imaging ; Thoracic Outlet Syndrome/drug therapy ; Thrombolytic Therapy ; Treatment Outcome ; Upper Extremity ; Venous Thrombosis/drug therapy
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2020-10-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 645172-x
    ISSN 1758-1125 ; 0268-3555
    ISSN (online) 1758-1125
    ISSN 0268-3555
    DOI 10.1177/0268355520967519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2538: Show issues Location:
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  9. Article ; Online: Right elbow arthropathy in a patient with severe haemophilia A.

    Ferretti, Antonietta / Baldacci, Erminia / Chistolini, Antonio / Santoro, Cristina

    British journal of haematology

    2020  Volume 190, Issue 4, Page(s) 484

    MeSH term(s) Elbow Joint/diagnostic imaging ; Elbow Joint/pathology ; Factor VIII/therapeutic use ; Hemarthrosis/etiology ; Hemophilia A/complications ; Hemophilia A/drug therapy ; Humans ; Imaging, Three-Dimensional ; Immunoglobulin Fc Fragments/therapeutic use ; Joint Dislocations/diagnostic imaging ; Joint Dislocations/etiology ; Male ; Recombinant Fusion Proteins/therapeutic use ; Tomography, X-Ray Computed
    Chemical Substances Immunoglobulin Fc Fragments ; Recombinant Fusion Proteins ; factor VIII-Fc fusion protein ; F8 protein, human (839MOZ74GK) ; Factor VIII (9001-27-8)
    Language English
    Publishing date 2020-05-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16707
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  10. Article ; Online: Direct oral anticoagulants for the treatment of atrial fibrillation in patients with hematologic malignancies.

    Serrao, Alessandra / Malfona, Francesco / Assanto, Giovanni Manfredi / Orellana, Maria Gabriela Chavez / Santoro, Cristina / Chistolini, Antonio

    Journal of thrombosis and thrombolysis

    2022  Volume 54, Issue 4, Page(s) 625–629

    Abstract: Atrial fibrillation (AF) is common in patients with cancer due to both the proinflammatory effect of neoplastic cells and to cardiotoxicity of anti-tumor therapies. Anticoagulation is still challenging in cancer patients due to increased bleeding risk ... ...

    Abstract Atrial fibrillation (AF) is common in patients with cancer due to both the proinflammatory effect of neoplastic cells and to cardiotoxicity of anti-tumor therapies. Anticoagulation is still challenging in cancer patients due to increased bleeding risk related to specific neoplasms such us hematologic malignancies. The aim of this retrospective study was to evaluate the safety and the efficacy of direct oral anticoagulants (DOACs) in AF patients affected by hematologic neoplasms. We included 97 patients on active anticancer treatment. The median follow-up was 25 months (range 10-108). No thromboembolic complications occurred, while 14 bleeding events were recorded: 1 major, 12 clinical relevant non major bleeding and 1 minor bleeding. Although retrospective and with a small number of enrolled patients, our data support the efficacy and safety of DOACs in patients affected by hematologic malignancies suggesting caution to particular situations, such as thrombocytopenia.
    MeSH term(s) Humans ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Retrospective Studies ; Administration, Oral ; Anticoagulants/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Hematologic Neoplasms/complications ; Hematologic Neoplasms/drug therapy ; Hematologic Neoplasms/pathology ; Neoplasms/complications ; Stroke/drug therapy
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-09-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1230645-9
    ISSN 1573-742X ; 0929-5305
    ISSN (online) 1573-742X
    ISSN 0929-5305
    DOI 10.1007/s11239-022-02702-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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