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Article ; Online: Sodium/Glucose Cotransporter 2 Inhibitors and Magnesium Homeostasis.

Shah, Chintan V / Sparks, Matthew A / Lee, Chien-Te

American journal of kidney diseases : the official journal of the National Kidney Foundation

2024

Abstract: Magnesium ( ... ...

Abstract	Magnesium (Mg
Language	English
Publishing date	2024-02-16
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604539-x
ISSN	1523-6838 ; 0272-6386
ISSN (online)	1523-6838
ISSN	0272-6386
DOI	10.1053/j.ajkd.2023.11.006
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Article ; Online: Predictors of Self-Management Behaviors After Discharge Among Unplanned Dialysis Patients.

Kao, Yu-Yin / Lee, Chien-Te / Wang, Ruey-Hsia

The journal of nursing research : JNR

2023 Volume 31, Issue 2, Page(s) e267

Abstract: Background: Patients with unplanned dialysis must perform self-management behaviors to maintain their health in the community after discharge. Understanding the factors that predict the postdischarge self-management behaviors of patients with unplanned ... ...

Abstract	Background: Patients with unplanned dialysis must perform self-management behaviors to maintain their health in the community after discharge. Understanding the factors that predict the postdischarge self-management behaviors of patients with unplanned dialysis can assist nurses to implement appropriate discharge plans for this population. Purpose: This study was designed to predict the effects of uncertainty in illness, self-care knowledge, and social-support-related needs during hospitalization on the self-management behaviors of patients with unplanned dialysis during their first 3 months after discharge from the hospital. Methods: One hundred sixty-nine patients with unplanned dialysis from the nephrology department of a medical center in Taiwan were enrolled in this prospective study using convenience sampling. At hospital admission, demographic, uncertainty in illness, self-care knowledge, and social support information was collected using a structured questionnaire. Information on self-management behavior was collected at 3 months postdischarge when the patients visited outpatient clinics. Results: Hierarchical multiple regression analyses showed that self-care knowledge, uncertainty in illness, and social support were important predictors of self-management behaviors at 3 months postdischarge, explaining 65.6% of the total variance in self-management behaviors. Social support increased the variance in self-management behaviors by 27.9%. Conclusions/implications for practice: Comprehensive discharge planning to improve the postdischarge self-management behaviors of patients with unplanned dialysis should involve interventions to improve self-care knowledge, reduce uncertainty in illness, and increase social support. Building social support should be given priority attention.
MeSH term(s)	Humans ; Patient Discharge ; Prospective Studies ; Renal Dialysis/nursing ; Self-Management/psychology ; Male ; Female ; Middle Aged ; Aged ; Health Knowledge, Attitudes, Practice ; Taiwan ; Social Support ; Surveys and Questionnaires ; Regression Analysis
Language	English
Publishing date	2023-04-01
Publishing country	China (Republic : 1949- )
Document type	Journal Article
ZDB-ID	2277010-0
ISSN	1948-965X ; 1682-3141
ISSN (online)	1948-965X
ISSN	1682-3141
DOI	10.1097/jnr.0000000000000523
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Book ; Online: Sea Surface temperatures of warm and cold seasons calculated from planktic foraminifera in sediment core MD97-2151, supplementary data to: Huang, Chin-Chien; Chen, Min-Te; Lee, Meng-Yang; Wei, Kuo-Yen; Huang, Chi-Yue (2002): Planktic foraminifer faunal sea surface temperature records of the past two glacial terminations in the South China Sea near Wan-An shallow (IMAGES core MD972151). Western Pacific Earth Sciences, 2(1), 1-14

Huang, Chin-Chien / Chen, Min-Te / Huang, Chi-Yue / Lee, Meng-Yang / Wei, Kuo-Yen

2003

Abstract: The South China Sea is the largest marginal sea of southeastern Asia, lying presently under the influences of the Western Pacific Warm Pool and Asian monsoon systems. Sediment cores from this area provide high-resolution records for interpreting ... ...

Abstract	The South China Sea is the largest marginal sea of southeastern Asia, lying presently under the influences of the Western Pacific Warm Pool and Asian monsoon systems. Sediment cores from this area provide high-resolution records for interpreting millennial- to centennial-scales paleoclimatic changes expressed in the western Pacific. Here we present results of high-resolution paleoceanographic data including planktic foraminifer fauna sea surface temperature (SST) anddepth of thermocline (DOT) estimates along with foraminifer stable isotopes, alkenone SST estimates analyzed froma core takenfrom the southern South China Sea (SCS) near Wan-An Shallow (IMAGES III 1997 cruise core MD97-2151). The intervals of the record presented here cover the past two glacial Terminations (centering at ab. 12,000 and 128,000 yrs B.P.). Our analyses of SST estimates by using planktic foraminifer transfer functions with paralleling measurements of alkenone SST methods all show events of rapid cooling reversals occurrring during the Termination I concurrent with the Younger Dryas (ab. 13-11 kyr B.P.), and Heinrich events reported previously from GISP2 ice core and North Atlantic core studies. Our reconstructions indicate also that theTermination I inthe southern SCS is characterized by a change of monsoon wind systems, with probably much stronger winter monsoon winds in the glacial period. We also found that during the Termination II, there was no such climatic reversal analogous to the Younger Dryas. During oxygen isotope stage 5, our estimates of SST and DOT, and abundances of deep-dwelling planktic foraminifer species all show large-amplitude variations, indicating an instability of monsoon climate during the interglacial period. Our studies also highlight the climatic teleconnections shown by the linkage of the SCS and other regional records for examples from the East China Sea and Chinese loess.
Language	English
Dates of publication	2003-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to hdl:10013/epic.37314.d001
DOI	10.1594/PANGAEA.114675
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Effect of a Pay-for-Performance Program on Renal Outcomes Among Patients With Early-Stage Chronic Kidney Disease in Taiwan

Min-Ting Lin / Chien-Ning Hsu / Chien-Te Lee / Shou-Hsia Cheng

International Journal of Health Policy and Management, Vol 11, Iss 8, Pp 1307-

2022 Volume 1315

Abstract: Background With the promising outcomes of the pre-ESRD (end-stage renal disease) pay-for-performance (P4P) program, the National Health Insurance Administration (NHIA) of Taiwan launched a P4P program for patients with early chronic kidney disease (CKD) ... ...

Abstract	Background With the promising outcomes of the pre-ESRD (end-stage renal disease) pay-for-performance (P4P) program, the National Health Insurance Administration (NHIA) of Taiwan launched a P4P program for patients with early chronic kidney disease (CKD) in 2011, targeting CKD patients at stages 1, 2, and 3a. This study aimed to examine the long-term effect of the early-CKD P4P program on CKD progression. Methods We conducted a matched cohort study using electronic medical records from a large healthcare delivery system in Taiwan. The outcome of interest was CKD progression to estimated glomerular filtration rate (eGFR) 2 between P4P program enrolees and non-enrolees. The difference in the cumulative incidence of CKD progression between the P4P and non-P4P groups was tested using Gray’s test. We adopted a cause-specific (CS) hazard model to estimate the hazard in the P4P group as compared to non-P4P group, adjusting for age, sex, baseline renal function, and comorbidities. A subgroup analysis was further performed in CKD patients with diabetes to evaluate the interactive effects between the early-CKD P4P and diabetes P4P programs. Results The incidence per 100 person-months of disease progression was significantly lower in the P4P group than in the non-P4P group (0.44 vs. 0.69, P < .0001), and the CS hazard ratio (CS-HR) for P4P program enrolees compared with non-enrolees was 0.61 (95% CI: 0.58–0.64, P < .0001). The results of the subgroup analysis further revealed an additive effect of the diabetes P4P program on CKD progression; compared to none of both P4P enrolees, the CS-HR for CKD disease progression was 0.60 (95% CI: 0.54–0.67, P < .0001) for patients who were enrolled in both early-CKD P4P and diabetes P4P programs. Conclusion The present study results suggest that the early-CKD P4P program is superior to usual care to decelerate CKD progression in patients with early-stage CKD.
Keywords	pay-for-performance ; chronic kidney disease ; cohort study ; renal outcome ; electronic medical records ; taiwan ; Public aspects of medicine ; RA1-1270
Subject code	616
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Kerman University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: A Pilot Study of the Effects on an Inpatient Geriatric Consultation Team on Geriatric Syndrome Patients.

Loke, Song-Seng / Lee, Chien-Te / Huang, Shan / Chen, Chao-Tung

International journal of general medicine

2022 Volume 15, Page(s) 5051–5060

Abstract: Purpose: To evaluate the effect of comprehensive geriatric assessment performed by an inpatient aging consultation team on older patients with geriatric syndromes.: Methods: Fifty-nine patients with ≧65 years, Barthel Index score ≦60, at least one ... ...

Abstract	Purpose: To evaluate the effect of comprehensive geriatric assessment performed by an inpatient aging consultation team on older patients with geriatric syndromes. Methods: Fifty-nine patients with ≧65 years, Barthel Index score ≦60, at least one geriatric syndrome, and admitted to non-geriatric wards were enrolled. By their preference, 16 were in the intervention group with comprehensive geriatric assessment and instructions from the consultation team. And 43 were in the control group, receiving standard care from non-geriatric-specialist physicians. Outcomes were readmission and mortality within one year after discharge. Results: The mean age of the intervention and control groups was 78.35 (8.54) and 80.23 (6.36) years (p = 0.36), with female of 62.5% and 60.5%, respectively. Compared to control, intervention is not significantly associated with attenuated risk for readmission (adjusted hazard ratio (aHR): 0.256, 95% confidence interval (CI): 0.12-1.78, p = 0.256) and mortality (aHR: 2.13, 95% CI: 0.29-15.7, p = 0.457) within one year after discharge. Multivariate analysis showed that patients with a fall history ≧1 in the past one year had a lower risk of readmission (aHR: 0.28, 0.07-0.6, p = 0.004) or mortality (aHR: 0.11, 95% CI: 0.01-0.97, p = 0.047), and disability is associated with mortality (aHR: 5.37, 95% CI: 0.87-33.12, p = 0.07). Conclusion: Intervention is not significantly associated with outcomes in our pilot study. But fall history ≧1 in the recent one year is associated with a lower risk of readmission and mortality among all included patients. More participants and longer follow-up are needed for better elucidation.
Language	English
Publishing date	2022-05-17
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S363543
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Article ; Online: Effect of a Pay-for-Performance Program on Renal Outcomes Among Patients With Early-Stage Chronic Kidney Disease in Taiwan.

Lin, Min-Ting / Hsu, Chien-Ning / Lee, Chien-Te / Cheng, Shou-Hsia

International journal of health policy and management

2021 Volume 11, Issue 8, Page(s) 1307–1315

Abstract: Background: With the promising outcomes of the pre-ESRD (end-stage renal disease) pay-for-performance (P4P) program, the National Health Insurance Administration (NHIA) of Taiwan launched a P4P program for patients with early chronic kidney disease (CKD) ...

Abstract	Background: With the promising outcomes of the pre-ESRD (end-stage renal disease) pay-for-performance (P4P) program, the National Health Insurance Administration (NHIA) of Taiwan launched a P4P program for patients with early chronic kidney disease (CKD) in 2011, targeting CKD patients at stages 1, 2, and 3a. This study aimed to examine the long-term effect of the early-CKD P4P program on CKD progression. Methods: We conducted a matched cohort study using electronic medical records from a large healthcare delivery system in Taiwan. The outcome of interest was CKD progression to estimated glomerular filtration rate (eGFR) <45 mL/min/1.73 m Results: The incidence per 100 person-months of disease progression was significantly lower in the P4P group than in the non-P4P group (0.44 vs. 0.69, Conclusion: The present study results suggest that the early-CKD P4P program is superior to usual care to decelerate CKD progression in patients with early-stage CKD.
MeSH term(s)	Humans ; Cohort Studies ; Reimbursement, Incentive ; Taiwan/epidemiology ; Renal Insufficiency, Chronic/therapy ; Kidney Failure, Chronic/therapy ; Kidney Failure, Chronic/epidemiology ; Diabetes Mellitus ; Kidney/physiology ; Disease Progression
Language	English
Publishing date	2021-04-13
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2724317-5
ISSN	2322-5939 ; 2322-5939
ISSN (online)	2322-5939
ISSN	2322-5939
DOI	10.34172/ijhpm.2021.27
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Article ; Online: Long-term safety and efficacy of methotrexate in patients with palindromic rheumatism.

Ma, Kevin Sheng-Kai / Liu, Chien-Te / Kao, Wei-Chiao / Lee, Yung-Heng

International journal of rheumatic diseases

2022 Volume 25, Issue 12, Page(s) 1448–1449

MeSH term(s)	Humans ; Methotrexate/adverse effects ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Rheumatic Diseases/diagnosis ; Rheumatic Diseases/drug therapy
Chemical Substances	Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2022-08-19
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2426924-4
ISSN	1756-185X ; 1756-1841
ISSN (online)	1756-185X
ISSN	1756-1841
DOI	10.1111/1756-185X.14420
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Article: Perception and Mental Health Status Regarding COVID-19 Vaccination Among Taiwanese Adolescents and Their Caregivers.

Hwang, Jade Winjei / Chien, Shao Ju / Wang, Chih-Chi / Kuo, Kuang-Che / Tang, Kuo-Shu / Lee, Yu / Chen, Yi-Chun / Lo, Mao-Hung / Lee, Ing-Kit / Chuah, Seng-Kee / Lee, Chien-Te / Kung, Chia-Te / Wang, Liang-Jen

Adolescent health, medicine and therapeutics

2023 Volume 14, Page(s) 195–204

Abstract: Background: Vaccinating adolescents is a vital strategy to enhance population protection without imposing overly restrictive measures on our daily lives during the COVID-19 pandemic. As teenagers gain more independence, their willingness to get ... ...

Abstract	Background: Vaccinating adolescents is a vital strategy to enhance population protection without imposing overly restrictive measures on our daily lives during the COVID-19 pandemic. As teenagers gain more independence, their willingness to get vaccinated may depend on their own understanding of the pandemic, vaccines, and mental well-being, as well as that of their caregivers. Our study aimed to examine how Taiwanese adolescents and their caregivers perceive COVID-19 vaccination and assess their mental health status. Methods: We invited a total of 138 vaccinated adolescents and their caregivers to complete several questionnaires, including the Drivers of COVID-19 Vaccination Acceptance Scale (DrVac-COVID19S), Impact of Event Scale (IES), and Chinese Health Questionnaire (CHQ). Results: Among the adolescents, 76.8% considered the BNT162b2 vaccine (Pfizer-BioNTech) as the ideal option for COVID-19 vaccination, while 27.5% of caregivers expressed acceptance of any available vaccine. Adolescents scored higher than caregivers in terms of vaccine value (p<0.001) and autonomy (p<0.001), but lower in knowledge (p<0.001), as assessed by the DrVac-COVID19S subscales. The adolescents' intention to get vaccinated against COVID-19 (DrVac-COVID19S total score) showed a positive correlation with their perception of the pandemic's impact (IES scores, r=0.214, p=0.012) and their caregivers' vaccination intention (r=0.371, p<0.001). Furthermore, adolescents' mental health demonstrated a positive association with the mental health of their caregiver (CHQ total scores, r=0.481, p<0.001). Conclusion: During the COVID-19 outbreak, caregivers have encountered heightened levels of mental stress, and this stress has been found to be positively correlated with the mental stress experienced by adolescents and their intentions regarding vaccination. These findings can serve as crucial references for healthcare providers and governments when formulating vaccination policies for adolescents in the future.
Language	English
Publishing date	2023-10-05
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2587456-1
ISSN	1179-318X
ISSN	1179-318X
DOI	10.2147/AHMT.S429238
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Article: Exogenous BMP7 administration attenuated vascular calcification and improved bone disorders in chronic uremic rats

Lee, Chien-Te / Kuo, Wei-Hung / Tain, You-Lin / Wang, Yi / Lee, Wen-Chin

Biochemical and biophysical research communications. 2022 Sept. 17, v. 621

2022

Abstract: Vascular calcification is commonly observed in chronic kidney disease (CKD) and is associated with increased morbidity and mortality. This study examined whether exogenous BMP7 administration can modulate disturbed CKD-MBD in adenine-induced chronic ... ...

Abstract	Vascular calcification is commonly observed in chronic kidney disease (CKD) and is associated with increased morbidity and mortality. This study examined whether exogenous BMP7 administration can modulate disturbed CKD-MBD in adenine-induced chronic uremic rats. After an adenine diet for 4 weeks, the animals were injected with BMP7 for 2 weeks. Biochemical data, kidney tissue, bony structure, and vascular calcification of the thoracic aorta were examined and compared. Reduced renal function, hyperphosphatemia, and hyperparathyroidism with low 1,25(OH)2 vitamin D levels were observed in the adenine group. MicroCT revealed reduced bone mineral density (BMD), decreased bone and tissue volume ratio (BV/TV), and decreased trabecular number with increased separation. Marked vascular calcification was observed in adenine-fed animals, and immunohistochemical analysis showed increased expression of BMP2, RUNX2, vitamin D receptor (VDR), and Pit1 in aortic tissue. Treatment with BMP7 was associated with reduced serum phosphate, intact parathyroid hormone, FGF23, sclerostin, and DKK1 levels. BMP7 administration was accompanied with improvements in BMD and BV/TV. The increase in BMP2, RUNX2, VDR, and Pit1 was reversed by BMP7. In conclusion, exogenous BMP7 administration improved hyperphosphatemia and hyperparathyroidism in adenine-induced CKD. This treatment also attenuated vascular calcification and modulated structural abnormalities in the skeletal system.
Keywords	adenine ; aorta ; blood serum ; bone density ; calcification ; diet ; hyperparathyroidism ; immunohistochemistry ; kidney diseases ; kidneys ; micro-computed tomography ; morbidity ; mortality ; parathyroid hormone ; phosphates ; renal function ; research
Language	English
Dates of publication	2022-0917
Size	p. 8-13.
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	205723-2
ISSN	0006-291X ; 0006-291X
ISSN (online)	0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2022.06.101
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Article ; Online: Exogenous BMP7 administration attenuated vascular calcification and improved bone disorders in chronic uremic rats.

Lee, Chien-Te / Kuo, Wei-Hung / Tain, You-Lin / Wang, Yi / Lee, Wen-Chin

Biochemical and biophysical research communications

2022 Volume 621, Page(s) 8–13

Abstract	Vascular calcification is commonly observed in chronic kidney disease (CKD) and is associated with increased morbidity and mortality. This study examined whether exogenous BMP7 administration can modulate disturbed CKD-MBD in adenine-induced chronic uremic rats. After an adenine diet for 4 weeks, the animals were injected with BMP7 for 2 weeks. Biochemical data, kidney tissue, bony structure, and vascular calcification of the thoracic aorta were examined and compared. Reduced renal function, hyperphosphatemia, and hyperparathyroidism with low 1,25(OH)2 vitamin D levels were observed in the adenine group. MicroCT revealed reduced bone mineral density (BMD), decreased bone and tissue volume ratio (BV/TV), and decreased trabecular number with increased separation. Marked vascular calcification was observed in adenine-fed animals, and immunohistochemical analysis showed increased expression of BMP2, RUNX2, vitamin D receptor (VDR), and Pit1 in aortic tissue. Treatment with BMP7 was associated with reduced serum phosphate, intact parathyroid hormone, FGF23, sclerostin, and DKK1 levels. BMP7 administration was accompanied with improvements in BMD and BV/TV. The increase in BMP2, RUNX2, VDR, and Pit1 was reversed by BMP7. In conclusion, exogenous BMP7 administration improved hyperphosphatemia and hyperparathyroidism in adenine-induced CKD. This treatment also attenuated vascular calcification and modulated structural abnormalities in the skeletal system.
MeSH term(s)	Adenine ; Animals ; Bone Morphogenetic Protein 7/therapeutic use ; Core Binding Factor Alpha 1 Subunit ; Hyperphosphatemia/complications ; Rats ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy ; Vascular Calcification/drug therapy ; Vascular Calcification/metabolism
Chemical Substances	Bmp7 protein, rat ; Bone Morphogenetic Protein 7 ; Core Binding Factor Alpha 1 Subunit ; Adenine (JAC85A2161)
Language	English
Publishing date	2022-07-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205723-2
ISSN	1090-2104 ; 0006-291X ; 0006-291X
ISSN (online)	1090-2104 ; 0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2022.06.101
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