LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 348

Search options

  1. Book: Wissenschaft und Karriere in der Medizin

    Griese, Matthias

    ein Leitfaden für Studierende und Ärzte

    2012  

    Author's details Matthias Griese
    Keywords Medizin ; Hochschule ; Forschung ; Karriereplanung ; Wissenschaftliches Arbeiten
    Subject Hochschulwesen ; Hochschulsystem ; Hochschulen ; Humanmedizin ; Heilkunst ; Medicine ; Wissenschaftliche Arbeit ; Wissenschaftliche Arbeitstechnik ; Laufbahnplanung ; Wissenschaftliche Forschung ; Forschungen
    Language German
    Size X, 131 S. : graph. Darst.
    Publisher Med.-Wiss. Verl.-Ges
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT016939791
    ISBN 978-3-941468-62-7 ; 3-941468-62-6
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 332 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Etiologic Classification of Diffuse Parenchymal (Interstitial) Lung Diseases.

    Griese, Matthias

    Journal of clinical medicine

    2022  Volume 11, Issue 6

    Abstract: Interstitial lung diseases (ILD) or diffuse parenchymal lung diseases (DPLD) comprise a large number of disorders. Disease definition and classification allow advanced and personalized judgements on clinical disease, risks for genetic or environmental ... ...

    Abstract Interstitial lung diseases (ILD) or diffuse parenchymal lung diseases (DPLD) comprise a large number of disorders. Disease definition and classification allow advanced and personalized judgements on clinical disease, risks for genetic or environmental transmissions, and precision medicine treatments. Registers collect specific rare entities and use ontologies for a precise description of complex phenotypes. Here we present a brief history of ILD classification systems from adult and pediatric pneumology. We center on an etiologic classification, with four main categories: lung-only (native parenchymal) disorders, systemic disease-related disorders, exposure-related disorders, and vascular disorders. Splitting diseases into molecularly defined entities is key for precision medicine and the identification of novel entities. Lumping diseases targeted by similar diagnostic or therapeutic principles is key for clinical practice and register work, as our experience with the European children's ILD register (chILD-EU) demonstrates. The etiologic classification favored combines pediatric and adult lung diseases in a single system and considers genomics and other -omics as central steps towards the solution of "idiopathic" lung diseases. Future tasks focus on a systems' medicine approach integrating all data and bringing precision medicine closer to the patients.
    Language English
    Publishing date 2022-03-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11061747
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Etiologic Classification of Diffuse Parenchymal (Interstitial) Lung Diseases

    Matthias Griese

    Journal of Clinical Medicine, Vol 11, Iss 1747, p

    2022  Volume 1747

    Abstract: Interstitial lung diseases (ILD) or diffuse parenchymal lung diseases (DPLD) comprise a large number of disorders. Disease definition and classification allow advanced and personalized judgements on clinical disease, risks for genetic or environmental ... ...

    Abstract Interstitial lung diseases (ILD) or diffuse parenchymal lung diseases (DPLD) comprise a large number of disorders. Disease definition and classification allow advanced and personalized judgements on clinical disease, risks for genetic or environmental transmissions, and precision medicine treatments. Registers collect specific rare entities and use ontologies for a precise description of complex phenotypes. Here we present a brief history of ILD classification systems from adult and pediatric pneumology. We center on an etiologic classification, with four main categories: lung-only (native parenchymal) disorders, systemic disease-related disorders, exposure-related disorders, and vascular disorders. Splitting diseases into molecularly defined entities is key for precision medicine and the identification of novel entities. Lumping diseases targeted by similar diagnostic or therapeutic principles is key for clinical practice and register work, as our experience with the European children’s ILD register (chILD-EU) demonstrates. The etiologic classification favored combines pediatric and adult lung diseases in a single system and considers genomics and other -omics as central steps towards the solution of “idiopathic” lung diseases. Future tasks focus on a systems’ medicine approach integrating all data and bringing precision medicine closer to the patients.
    Keywords children’s interstitial lung disease (chILD) ; human phenotype ontology ; interstitial pneumonia ; interstitial pneumonitis ; idiopathic interstitial fibrosis ; familial ; Medicine ; R
    Subject code 610 ; 006
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book: Praktische Pneumologie in der Pädiatrie - Therapie

    Griese, Matthias / Nicolai, Thomas

    Behandlung, Rehabilitation, Prophylaxe : Fallbeispiele

    2013  

    Author's details Matthias Griese ; Thomas Nicolai
    Keywords Kind ; Lungenkrankheit
    Subject Lungenerkrankung ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language German
    Size 574 S. : zahlr. Ill., graph. Darst.
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Accompanying material Zugang zu zusätzlichem Internetmaterial über Code
    HBZ-ID HT017202435
    ISBN 978-3-13-161171-0 ; 3-13-161171-5 ; 9783131611819 ; 3131611812
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 1952 available for loan (reading room) Lesesaal EG
    Zugang zu zusätzlichem Internetmaterial über Code aus lizenzrechtlichen Gründen nicht verfügbar

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Chronic interstitial lung disease in children.

    Griese, Matthias

    European respiratory review : an official journal of the European Respiratory Society

    2018  Volume 27, Issue 147

    Abstract: Children's interstitial lung diseases (chILD) are increasingly recognised and contain many lung developmental and genetic disorders not yet identified in adult pneumology. Worldwide, several registers have been established. The Australasian Registry ... ...

    Abstract Children's interstitial lung diseases (chILD) are increasingly recognised and contain many lung developmental and genetic disorders not yet identified in adult pneumology. Worldwide, several registers have been established. The Australasian Registry Network for Orphan Lung Disease (ARNOLD) has identified problems in estimating rare disease prevalence; focusing on chILD in immunocompetent patients, a period prevalence of 1.5 cases per million children and a mortality rate of 7% were determined. The chILD-EU register highlighted the workload to be covered per patient included and provided protocols for diagnosis and initial treatment, similar to the United States chILD network. Whereas case reports may be useful for young physicians to practise writing articles, cohorts of patients can catapult progress, as demonstrated by recent studies on persistent tachypnoea of infancy, hypersensitivity pneumonitis in children and interstitial lung disease related to interferonopathies from mutations in transmembrane protein 173. Translational research has linked heterozygous mutations in the ABCA3 transporter to an increased risk of interstitial lung diseases, not only in neonates, but also in older children and adults. For surfactant dysfunction disorders in infancy and early childhood, lung transplantation was reported to be as successful as in adult patients. Mutual potentiation of paediatric and adult pneumologists is mandatory in this rapidly extending field for successful future development.This brief review highlights publications in the field of paediatric interstitial lung disease as reviewed during the Clinical Year in Review session presented at the 2017 European Respiratory Society (ERS) Annual Congress in Milan, Italy. It was commissioned by the ERS and critically presents progress made as well as drawbacks.
    MeSH term(s) Adolescent ; Age of Onset ; Child ; Child, Preschool ; Evidence-Based Medicine ; Female ; Genetic Predisposition to Disease ; Humans ; Infant ; Infant, Newborn ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/epidemiology ; Lung Diseases, Interstitial/physiopathology ; Lung Diseases, Interstitial/therapy ; Male ; Prevalence ; Prognosis ; Pulmonary Medicine ; Registries ; Risk Factors
    Language English
    Publishing date 2018-02-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1077620-5
    ISSN 1600-0617 ; 0905-9180
    ISSN (online) 1600-0617
    ISSN 0905-9180
    DOI 10.1183/16000617.0100-2017
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3265: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Lung transplantation outcome in adult surfactant-related interstitial lung disease: first evidence to move on.

    Manali, Effrosyni D / Griese, Matthias / Papiris, Spyros A

    ERJ open research

    2023  Volume 9, Issue 6

    Abstract: A new study reports the first evidence to "move on" with lung transplantation in adult surfactant-related fibrotic ILDs. It highlights the need for better genetic characterisation of transplant candidates and cancer screening for these patients. ...

    Abstract A new study reports the first evidence to "move on" with lung transplantation in adult surfactant-related fibrotic ILDs. It highlights the need for better genetic characterisation of transplant candidates and cancer screening for these patients.
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Editorial
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00646-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Emerging Treatments for Childhood Interstitial Lung Disease.

    Bernardinello, Nicol / Griese, Matthias / Borie, Raphaël / Spagnolo, Paolo

    Paediatric drugs

    2023  Volume 26, Issue 1, Page(s) 19–30

    Abstract: Childhood interstitial lung disease (chILD) is a large and heterogeneous group of disorders characterized by diffuse lung parenchymal markings on chest imaging and clinical signs such as dyspnea and hypoxemia from functional impairment. While some ... ...

    Abstract Childhood interstitial lung disease (chILD) is a large and heterogeneous group of disorders characterized by diffuse lung parenchymal markings on chest imaging and clinical signs such as dyspnea and hypoxemia from functional impairment. While some children already present in the neonatal period with interstitial lung disease (ILD), others develop ILD during their childhood and adolescence. A timely and accurate diagnosis is essential to gauge treatment and improve prognosis. Supportive care can reduce symptoms and positively influence patients' quality of life; however, there is no cure for many of the chILDs. Current therapeutic options include anti-inflammatory or immunosuppressive drugs. Due to the rarity of the conditions and paucity of research in this field, most treatments are empirical and based on case series, and less than a handful of small, randomized trials have been conducted thus far. A trial on hydroxychloroquine yielded good safety but a much smaller effect size than anticipated. A trial in fibrotic disease with the multitargeted tyrosine kinase inhibitor nintedanib showed similar pharmacokinetics and safety as in adults. The unmet need for the treatment of chILDs remains high. This article summarizes current treatments and explores potential therapeutic options for patients suffering from chILD.
    MeSH term(s) Child ; Humans ; Immunosuppressive Agents/therapeutic use ; Lung ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/drug therapy ; Prognosis ; Protein Kinase Inhibitors/pharmacology ; Quality of Life
    Chemical Substances Immunosuppressive Agents ; Protein Kinase Inhibitors
    Language English
    Publishing date 2023-11-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1492748-2
    ISSN 1179-2019 ; 1174-5878
    ISSN (online) 1179-2019
    ISSN 1174-5878
    DOI 10.1007/s40272-023-00603-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5205: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Pulmonary Alveolar Proteinosis: A Comprehensive Clinical Perspective.

    Griese, Matthias

    Pediatrics

    2017  Volume 140, Issue 2

    Abstract: Pulmonary alveolar proteinosis is a broad group of rare diseases that are defined by the occupation of a lung's gas-exchange area by pulmonary surfactants that are not properly removed. The clinical and radiologic phenotypes among them are very similar. ... ...

    Abstract Pulmonary alveolar proteinosis is a broad group of rare diseases that are defined by the occupation of a lung's gas-exchange area by pulmonary surfactants that are not properly removed. The clinical and radiologic phenotypes among them are very similar. The age of manifestation plays a central role in the differential diagnosis of the almost 100 conditions and provides an efficient path to the correct diagnosis. The diagnostic approach is tailored to identify genetic or autoimmune causes, exposure to environmental agents, and associations with numerous other diseases. Whole-lung lavages are the cornerstone of treatment, and children in particular depend on the expertise to perform such therapeutic lavages. Other treatment options and long-term survival are related to the condition causing the proteinosis.
    MeSH term(s) Biopsy ; Bronchoalveolar Lavage/methods ; Bronchoscopy ; Child ; Diagnosis, Differential ; Humans ; Image Enhancement ; Lung/pathology ; Pulmonary Alveolar Proteinosis/diagnosis ; Pulmonary Alveolar Proteinosis/pathology ; Pulmonary Alveolar Proteinosis/physiopathology ; Pulmonary Alveolar Proteinosis/therapy ; Pulmonary Gas Exchange/physiology ; Pulmonary Surfactants/metabolism ; Tomography, X-Ray Computed
    Chemical Substances Pulmonary Surfactants
    Language English
    Publishing date 2017-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2017-0610
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.131: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 357: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Lung transplantation outcome in adult surfactant-related interstitial lung disease

    Effrosyni D. Manali / Matthias Griese / Spyros A. Papiris

    ERJ Open Research, Vol 9, Iss

    first evidence to move on

    2023  Volume 6

    Keywords Medicine ; R
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher European Respiratory Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book ; Online ; Thesis: Interstitial lung disease in immuno-compromised children and a novel monogenic defect

    Gao, Xianfei [Verfasser] / Griese, Matthias [Akademischer Betreuer]

    2023  

    Author's details Xianfei Gao ; Betreuer: Matthias Griese
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top