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  1. Article ; Online: Repositioning of the membranous septum to minimize pacemaker implantation after sutureless surgical aortic valve replacement.

    Ueki, Chikara / Nakanaga, Hiroshi / Tabata, Minoru

    JTCVS techniques

    2023  Volume 19, Page(s) 38–40

    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ISSN 2666-2507
    ISSN (online) 2666-2507
    DOI 10.1016/j.xjtc.2023.04.002
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  2. Article ; Online: Is the Transcarotid Approach Superior to the Subclavian/Axillary Approach?

    Ueki, Chikara / Tsuneyoshi, Hiroshi

    The Annals of thoracic surgery

    2021  Volume 113, Issue 1, Page(s) 376

    MeSH term(s) Humans ; Pacemaker, Artificial ; Subclavian Vein/diagnostic imaging ; Subclavian Vein/surgery
    Language English
    Publishing date 2021-03-08
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2021.01.081
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  3. Article ; Online: Are Residual Reentry Tears Eligible for Preemptive Endovascular Aortic Repair?

    Ueki, Chikara / Tsuneyoshi, Hiroshi

    The Annals of thoracic surgery

    2020  Volume 112, Issue 1, Page(s) 343

    Language English
    Publishing date 2020-12-03
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.08.116
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  4. Article ; Online: Continuous low serum levels of advanced glycation end products and low risk of cardiovascular disease in patients with poorly controlled type 2 diabetes.

    Nakamura, Tomoka / Tsujimoto, Tetsuro / Yasuda, Kazuki / Ueki, Kohjiro / Kajio, Hiroshi

    Cardiovascular diabetology

    2023  Volume 22, Issue 1, Page(s) 147

    Abstract: Background: Type 2 diabetes is associated with an increased risk of developing cardiovascular events. Previous studies have reported that advanced glycation end products (AGEs) were related to cardiovascular events in type 2 diabetes. However, data on ... ...

    Abstract Background: Type 2 diabetes is associated with an increased risk of developing cardiovascular events. Previous studies have reported that advanced glycation end products (AGEs) were related to cardiovascular events in type 2 diabetes. However, data on associations between long-term AGEs and cardiovascular events in type 2 diabetes are lacking. This study aimed to determine whether a long-time shift in the levels of serum AGEs is associated with cardiovascular events in patients with poorly controlled type 2 diabetes.
    Methods: Two-time serum methyl-glyoxal-hydroimidazoline (MG-H1) levels were measured in 138 patients with type 2 diabetes whose mean glycated hemoglobin level was 10.1%. We categorized patients whose serum MG-H1 levels were < 2.8 µg/mL at both times as the continuous low MG-H1 group. The primary endpoints of this study were combined cardiovascular events, which were defined as heart disease, peripheral arterial disease, stroke, and all-cause death. Hazard ratios (HRs) for combined cardiovascular events with 95% confidence intervals (CIs) were calculated using the Cox proportional hazard models to compare the outcomes between the continuous low MG-H1 group and others.
    Results: The continuous low MG-H1 group was associated with a significantly lower risk than others in combined cardiovascular events after adjusting for possible confounders (HR: 0.50; 95% CI, 0.28-0.87; P = 0.02). Furthermore, the same relationship was observed in patients without a history of cardiovascular events.
    Conclusions: Continuous low serum MG-H1 levels are associated with a low frequency of diabetes-related complications in patients with poorly controlled type 2 diabetes.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/epidemiology ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Glycation End Products, Advanced ; Diabetes Complications/complications ; Time
    Chemical Substances Glycation End Products, Advanced
    Language English
    Publishing date 2023-06-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2093769-6
    ISSN 1475-2840 ; 1475-2840
    ISSN (online) 1475-2840
    ISSN 1475-2840
    DOI 10.1186/s12933-023-01882-9
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  5. Article ; Online: Late Aortic Expansion After Thoracic Endovascular Aortic Repair for Chronic DeBakey IIIb Dissection.

    Ueki, Chikara / Tsuneyoshi, Hiroshi

    The Annals of thoracic surgery

    2020  Volume 111, Issue 4, Page(s) 1271–1277

    Abstract: Background: The efficacy of thoracic endovascular aortic repair (TEVAR) for chronic DeBakey IIIb aortic dissection is still under discussion. This study was performed to investigate the incidence of and risk factors for late aortic expansion after TEVAR ...

    Abstract Background: The efficacy of thoracic endovascular aortic repair (TEVAR) for chronic DeBakey IIIb aortic dissection is still under discussion. This study was performed to investigate the incidence of and risk factors for late aortic expansion after TEVAR for chronic DeBakey IIIb aortic dissection.
    Methods: From March 2014 to April 2019, a total of 35 patients with chronic DeBakey IIIb aortic dissection underwent TEVAR in our institution. Risk factors for aortic expansion events were examined by stepwise Cox regression analysis. Aortic expansion events were defined as reintervention for expansion or aortic expansion of greater than 5 mm.
    Results: No operative death occurred, and the 2-year survival rate was 96.8%. The 1- and 2-year rates of freedom from reintervention were 87.8% and 80.2%, respectively. During follow-up, 11 patients had late aortic expansion events (4 with expansion of the thoracic aorta and 7 with expansion of the abdominal aorta). The 1- and 2-year rates of freedom from aortic expansion were 87.8% and 68.7%, respectively. Significant risk factors for expansion events were aortic dilation at the celiac level (hazard ratio [HR], 1.11; P = .015), saccular aneurysm formation of the false lumen (HR, 5.08; P = .049), and high number of residual large reentries (>5 mm) (HR, 2.78; P = .027).
    Conclusions: In patients undergoing TEVAR for chronic DeBakey IIIb aortic dissection, late aortic expansion in both the thoracic and abdominal aorta remains an important issue. Aggressive additional intervention should be considered for high-risk patients with residual large reentries and aortic dilation at the celiac level.
    MeSH term(s) Aged ; Aneurysm, Dissecting/diagnosis ; Aneurysm, Dissecting/surgery ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic/diagnosis ; Aortic Aneurysm, Thoracic/surgery ; Aortography ; Blood Vessel Prosthesis Implantation/methods ; Chronic Disease ; Disease Progression ; Endovascular Procedures/methods ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome
    Language English
    Publishing date 2020-08-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.06.070
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 252: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Clinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study.

    Imamura, Kentaro / Yao, Kenshi / Nimura, Satoshi / Kanemitsu, Takao / Miyaoka, Masaki / Ono, Yoichiro / Ueki, Toshiharu / Tanabe, Hiroshi

    Clinical endoscopy

    2024  

    Abstract: Background/aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC.: Methods!# ...

    Abstract Background/aims: Helicobacter pylori infection-negative gastric cancer (HPNGC) has not been systematically investigated in consecutive patients. Hence, this study aimed to investigate the clinicopathological and endoscopic features of HPNGC.
    Methods: This single-center retrospective study selected participants from patients with gastric cancer who were treated at the Fukuoka University Chikushi Hospital between January 2013 and December 2021. Only patients diagnosed with HPNGC were enrolled, and their clinicopathological and endoscopic features were analyzed in detail.
    Results: The prevalence of HPNGC in the present study was 2.6% (54/2112). The types of HPNGC observed in each gastric region were as follows: advanced gastric cancer was observed in the cardia; gastric adenocarcinoma of fundic-gland differentiation, gastric adenocarcinoma of foveolar-type presenting with whitish elevation and raspberry-like foveolar-type gastric adenocarcinoma, gastric adenocarcinoma arising in polyposis, and gastric adenocarcinoma with autoimmune gastritis were observed in the fundic gland region ranging from the gastric fornix to the gastric body; signet-ring cell carcinoma was observed in the gastric-pyloric transition region ranging from the lower gastric body to the gastric angle; and well-differentiated tubular adenocarcinoma with low-grade atypia was observed in the antrum.
    Conclusions: This study revealed that tumors from each gastric region exhibited distinct macroscopic and histological types in HPNGC.
    Language English
    Publishing date 2024-03-22
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2643507-X
    ISSN 2234-2443 ; 2234-2400
    ISSN (online) 2234-2443
    ISSN 2234-2400
    DOI 10.5946/ce.2023.258
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  7. Article ; Online: Unusual paired hepatocellular carcinoma recurrence in the biliary system after liver resection and endoscopic sphincterotomy.

    Kagoura, Masaaki / Sadamori, Hiroshi / Ueki, Toru

    Journal of hepato-biliary-pancreatic sciences

    2021  Volume 28, Issue 5, Page(s) e21–e23

    Abstract: Highlight Kagoura and colleagues report a rare case of paired hepatocellular carcinoma recurrence after hepatectomy with removal of a bile duct tumor thrombosis following endoscopic sphincterotomy. Recurrence is believed to have occurred both at the ... ...

    Abstract Highlight Kagoura and colleagues report a rare case of paired hepatocellular carcinoma recurrence after hepatectomy with removal of a bile duct tumor thrombosis following endoscopic sphincterotomy. Recurrence is believed to have occurred both at the stump of the hepatic bile duct and at the post-sphincterotomy site of the papilla of Vater.
    MeSH term(s) Bile Ducts ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/surgery ; Cholangiopancreatography, Endoscopic Retrograde ; Hepatectomy/adverse effects ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/surgery ; Neoplasm Recurrence, Local/surgery ; Sphincterotomy, Endoscopic
    Language English
    Publishing date 2021-02-17
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2536236-7
    ISSN 1868-6982 ; 1868-6974
    ISSN (online) 1868-6982
    ISSN 1868-6974
    DOI 10.1002/jhbp.907
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    Zs.A 4024: Show issues Location:
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  8. Article ; Online: Development of a Mouse-Adapted Reporter SARS-CoV-2 as a Tool for Two-Photon In Vivo Imaging.

    Ueki, Hiroshi / Kiso, Maki / Furusawa, Yuri / Iida, Shun / Yamayoshi, Seiya / Nakajima, Noriko / Imai, Masaki / Suzuki, Tadaki / Kawaoka, Yoshihiro

    Viruses

    2024  Volume 16, Issue 4

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) often causes severe viral pneumonia. Although many studies using mouse models have examined the pathogenicity of SARS-CoV-2, COVID-19 pathogenesis remains poorly understood. In vivo imaging ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) often causes severe viral pneumonia. Although many studies using mouse models have examined the pathogenicity of SARS-CoV-2, COVID-19 pathogenesis remains poorly understood. In vivo imaging analysis using two-photon excitation microscopy (TPEM) is useful for elucidating the pathology of COVID-19, providing pathological insights that are not available from conventional histological analysis. However, there is no reporter SARS-CoV-2 that demonstrates pathogenicity in C57BL/6 mice and emits sufficient light intensity for two-photon in vivo imaging. Here, we generated a mouse-adapted strain of SARS-CoV-2 (named MASCV2-p25) and demonstrated its efficient replication in the lungs of C57BL/6 mice, causing fatal pneumonia. Histopathologic analysis revealed the severe inflammation and infiltration of immune cells in the lungs of MASCV2-p25-infected C57BL/6 mice, not unlike that observed in COVID-19 patients with severe pneumonia. Subsequently, we generated a mouse-adapted reporter SARS-CoV-2 (named MASCV-Venus-p9) by inserting the fluorescent protein-encoding gene Venus into MASCV2-p25 and sequential lung-to-lung passages in C57BL/6 mice. C57BL/6 mice infected with MASCV2-Venus-p9 exhibited severe pneumonia. In addition, the TPEM of the lungs of the infected C57BL/6J mice showed that the infected cells emitted sufficient levels of fluorescence for easy observation. These findings suggest that MASCV2-Venus-p9 will be useful for two-photon in vivo imaging studies of the pathogenesis of severe COVID-19 pneumonia.
    MeSH term(s) Animals ; Mice ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; SARS-CoV-2/physiology ; COVID-19/virology ; Mice, Inbred C57BL ; Lung/virology ; Lung/pathology ; Lung/diagnostic imaging ; Disease Models, Animal ; Humans ; Genes, Reporter ; Virus Replication
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16040537
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  9. Article ; Online: Late false-lumen expansion predicted by preoperative blood flow simulation in a patient with chronic type B aortic dissection.

    Ueki, Chikara / Tsuneyoshi, Hiroshi

    The Journal of thoracic and cardiovascular surgery

    2018  Volume 157, Issue 6, Page(s) e311–e317

    MeSH term(s) Adult ; Aneurysm, Dissecting/diagnostic imaging ; Aneurysm, Dissecting/surgery ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/surgery ; Blood Circulation ; Endovascular Procedures ; Humans ; Male ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-10-14
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2018.09.108
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    Uk I Zs.104: Show issues Location:
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  10. Article ; Online: SGK1 in Schwann cells is a potential molecular switch involved in axonal and glial regeneration during peripheral nerve injury.

    Okura, Atsuhiko / Inoue, Koichi / Sakuma, Eisuke / Takase, Hiroshi / Ueki, Takatoshi / Mase, Mitsuhito

    Biochemical and biophysical research communications

    2022  Volume 607, Page(s) 158–165

    Abstract: Schwann cells play an important role in peripheral myelination, and dysfunction of these cells leads to axonal damage. Schwann cells degenerate following peripheral nerve injury. Immature Schwann cells proliferate, differentiate, and support axonal ... ...

    Abstract Schwann cells play an important role in peripheral myelination, and dysfunction of these cells leads to axonal damage. Schwann cells degenerate following peripheral nerve injury. Immature Schwann cells proliferate, differentiate, and support axonal regeneration and extension during recovery. There are a lot of intracellular signals involved in the myelination process. Although serum- and glucocorticoid-inducible kinase (SGK
    MeSH term(s) Animals ; Axons/metabolism ; Mice ; Nerve Regeneration/physiology ; Peripheral Nerve Injuries/metabolism ; Schwann Cells/metabolism ; Sciatic Nerve/metabolism
    Language English
    Publishing date 2022-03-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2022.03.123
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