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  1. Article: Shen-Yuan-Dan Capsule Attenuates Verapamil-Induced Zebrafish Heart Failure and Exerts Antiapoptotic and Anti-Inflammatory Effects via Reactive Oxygen Species-Induced NF-κB Pathway.

    Li, Sinai / Liu, Hongxu / Li, Yue / Qin, Xiaomei / Li, Mengjie / Shang, Juju / Xing, Wenlong / Gong, Yanbing / Liu, Weihong / Zhou, Mingxue

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 626515

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.626515
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Genetic and Transcriptomic Analysis Reveal the Molecular Basis of Photoperiod-Regulated Flowering in Xishuangbanna Cucumber (Cucumis sativus L. var. xishuangbannesis Qi et Yuan)

    Tian, Zhen / Jahn, Molly / Qin, Xiaodong / Obel, Hesbon Ochieng / Yang, Fan / Li, Ji / Chen, Jinfeng

    Genes. 2021 July 13, v. 12, no. 7

    2021  

    Abstract: Xishuangbanna (XIS) cucumber (Cucumis sativus L. var. xishuangbannesis Qi et Yuan), is a botanical ...

    Abstract Xishuangbanna (XIS) cucumber (Cucumis sativus L. var. xishuangbannesis Qi et Yuan), is a botanical variety of cucumber cultivars native to southwest China that possesses excellent agronomic traits for cucumber improvement. However, breeding utilization of XIS cucumber is limited due to the current poor understanding of its photoperiod-sensitive flowering characteristics. In this study, genetic and transcriptomic analysis were conducted to reveal the molecular basis of photoperiod-regulated flowering in XIS cucumber. A major-effect QTL locus DFF1.1 was identified that controls the days to first flowering (DFF) of XIS cucumbers with a span of 1.38 Mb. Whole-genome re-sequencing data of 9 cucumber varieties with different flowering characteristics in response to photoperiod suggested that CsaNFYA1 was the candidate gene of DFF1.1, which harbored a single non-synonymous mutation in its fifth exon. Transcriptomic analysis revealed the positive roles of auxin and ethylene in accelerating flowering under short-day (SD) light-dark cycles when compared with equal-day/night treatment. Carbohydrate storage and high expression levels of related genes were important reasons explaining early flowering of XIS cucumber under SD conditions. By combining with the RNA-Seq data, the co-expression network suggested that CsaNFYA1 integrated multiple types of genes to regulate the flowering of XIS cucumber. Our findings explain the internal regulatory mechanisms of a photoperiodic flowering pathway. These findings may guide the use of photoperiod shifts to promote flowering of photoperiod-sensitive crops.
    Keywords Cucumis sativus ; auxins ; carbohydrates ; cucumbers ; cultivars ; ethylene ; exons ; loci ; mutation ; sequence analysis ; transcriptomics ; China
    Language English
    Dates of publication 2021-0713
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2527218-4
    ISSN 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes12071064
    Database NAL-Catalogue (AGRICOLA)

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  3. Book: Yan jiu xing yi yuan guan li xue

    Qin, Yinhe

    Management science for research-oriented hospital

    2014  

    Title variant Management science for research-oriented hospital
    Author's details zhu bian Qin Yinhe
    MeSH term(s) Hospitals, Teaching/organization & administration ; Hospital Administration
    Keywords China
    Language Chinese
    Size 11, 976 pages :, illustrations
    Edition Di 1 ban.
    Document type Book
    ISBN 9787509180457 ; 7509180457
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Book: Er tong yi yuan gan ran guan li

    Qin, Xiaoping

    2015  

    Author's details zhu bian Qin Xiaoping
    MeSH term(s) Cross Infection/prevention & control ; Hospitals, Pediatric/organization & administration
    Keywords China
    Language Chinese
    Size 2, 254 pages :, illustrations
    Edition Di 1 ban.
    Document type Book
    ISBN 9787509180075 ; 7509180074
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Book: Song yuan ming kao gu

    Qin, Dashu

    (20 shi ji zhong guo wen wu kao gu fa xian yu yan jiu cong shu ; 20世纪中国文物考古发现与研究丛书)

    2005  

    Author's details Qin da shu
    Series title 20 shi ji zhong guo wen wu kao gu fa xian yu yan jiu cong shu ; 20世纪中国文物考古发现与研究丛书
    Language Chinese
    Dates of publication 2005-2004
    Size 322 p, Ill
    Edition Di 1 ban, di 2 ci yin shua
    Publisher Wen wu chu ban she
    Publishing place Bei jing
    Document type Book
    ISBN 7501016577 ; 9787501016570
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Yi fa yuan tong

    Zheng, Qin'an / Yu, Yongmin / Liu, Xiaoping

    (Ming Qing Zhong yi lin zheng xiao cong shu)

    1993  

    Author's details Zheng Shouquan zhu ; Yu Yongmin, Liu Xiaoping jiao zhu
    Series title Ming Qing Zhong yi lin zheng xiao cong shu
    MeSH term(s) Medicine, Chinese Traditional
    Language Chinese
    Size [8], 8, 142 p. ;, 19 cm.
    Edition Di 1 ban.
    Publisher Zhongguo Zhong yi yao chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787800891793 ; 7800891798
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Article ; Online: Inhibition of AT1R/IP3/IP3R-mediated Ca

    Hong, Sen-Yuan / Yang, Yuan-Yuan / Wang, Shao-Gang / Qin, Bao-Long

    Chemico-biological interactions

    2023  Volume 382, Page(s) 110636

    Abstract: Calcium oxalate (CaOx) stones are the most prevalent type of kidney stones. CaOx crystals can stimulate reactive oxygen species (ROS) generation and induce renal oxidative stress to promote stone formation. Intracellular ... ...

    Abstract Calcium oxalate (CaOx) stones are the most prevalent type of kidney stones. CaOx crystals can stimulate reactive oxygen species (ROS) generation and induce renal oxidative stress to promote stone formation. Intracellular Ca
    MeSH term(s) Rats ; Animals ; Calcium Oxalate/chemistry ; Reactive Oxygen Species/metabolism ; Losartan/metabolism ; Kidney/metabolism ; Kidney Calculi/chemically induced ; Kidney Calculi/prevention & control ; Oxidative Stress
    Chemical Substances Calcium Oxalate (2612HC57YE) ; Reactive Oxygen Species ; Losartan (JMS50MPO89)
    Language English
    Publishing date 2023-07-15
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 218799-1
    ISSN 1872-7786 ; 0009-2797
    ISSN (online) 1872-7786
    ISSN 0009-2797
    DOI 10.1016/j.cbi.2023.110636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 686: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Theoretical study of the synergic relationships between the design parameters in energy-saving building design.

    Huo, Hai 'e / Ji, YanHong / Qin, YuanYuan / Chen, ChaoZheng / Yuan, Ting

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4400

    Abstract: With the rapid development of the economy, people have increasingly higher requirements for the comfort of living spaces, and the result is the sharp increase in building energy consumption. Several design parameters influence living space comfort and ... ...

    Abstract With the rapid development of the economy, people have increasingly higher requirements for the comfort of living spaces, and the result is the sharp increase in building energy consumption. Several design parameters influence living space comfort and building energy efficiency. Since the same design standard can include different design parameter combinations, synergic relationships may exist between these criteria for one case. Identifying these synergic relationships requires an inverse problem approach. This paper established a model by combining an improved genetic algorithm (IGA) and numerical calculation to determine the synergic design parameter relationships (e.g. the thermophysical building material properties and energy-saving factors). For [Formula: see text], the shading coefficient significantly influenced the linear function between the thermal conductivity and insulation thickness. In this case, the insulation thickness was exponentially related to the shading coefficient, while the thermal conductivity of the insulation material significantly impacted the synergic relationship. For [Formula: see text], the insulation thickness was a segmented function of the shading coefficient. The results verified that the proposed model was efficient and reliable for identifying the synergic relationships between energy-saving parameters. In engineering applications, designers can select the optimal design parameter combination based on the relationship curve between the parameters in this paper according to the local market conditions and specific design requirements.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53735-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The combined detection of hematological indicators is used for the differential diagnosis of colorectal cancer and benign-colorectal lesions.

    Zhang, Xuan / Wu, Yang-Yang / Qin, Yuan-Yuan / Lin, Fa-Quan

    Cancer biomarkers : section A of Disease markers

    2024  Volume 39, Issue 3, Page(s) 223–230

    Abstract: Objective: This article aims to investigate the clinical value of hemoglobin/red cell distribution width ratio (Hb/RDW), C-reactive protein/albumin ratio (CAR) and plateletcrit (PCT) combined with carcinoembryonic antigen (CEA) in colorectal cancer (CRC) ...

    Abstract Objective: This article aims to investigate the clinical value of hemoglobin/red cell distribution width ratio (Hb/RDW), C-reactive protein/albumin ratio (CAR) and plateletcrit (PCT) combined with carcinoembryonic antigen (CEA) in colorectal cancer (CRC) auxiliary diagnosis.
    Methods: We retrospectively analyzed in 718 subjects (212 with CRC, 209 with benign colorectal lesions (BCL), 111 with other cancers, and 186 healthy controls).
    Results: The CAR, PCT, and CEA in the CRC group were higher than those in the BCL, other cancers, and the healthy control group. However, Hb/RDW in the CRC group was lower than the other three groups. Moreover, there were significant differences in Hb/RDW and CEA among different T-N-M stages (all P< 0.05). Multivariate logistic regression showed that low level of Hb/RDW and high level of CAR, CEA, PCT were risk factors for CRC, and are correlated with CRC stage. Additionally, the area under the receiver operating characteristic curve (AUC) of Hb/RDW+CEA (AUC: 0.735), CAR+CEA (AUC: 0.748), PCT+CEA (AUC: 0.807) was larger than that of Hb/RDW (AUC: 0.503), CAR (AUC: 0.614), or PCT (AUC: 0.713) alone (all P< 0.001) in distinguishing CRC from BCL.
    Conclusions: Hb/RDW, CAR, PCT, and CEA are independent risk factors for CRC. Hb/RDW, CAR, and PCT combined with CEA have significant value for auxiliary differential diagnosis of CRC and BCL.
    MeSH term(s) Humans ; Carcinoembryonic Antigen ; Biomarkers, Tumor ; Retrospective Studies ; Diagnosis, Differential ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/pathology ; Hemoglobins
    Chemical Substances Carcinoembryonic Antigen ; Biomarkers, Tumor ; Hemoglobins
    Language English
    Publishing date 2024-01-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2203517-5
    ISSN 1875-8592 ; 1574-0153 ; 1875-8592
    ISSN (online) 1875-8592 ; 1574-0153
    ISSN 1875-8592
    DOI 10.3233/CBM-230157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6127: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: The complete chloroplast genome of

    Zheng, Yu-Mei / Qin, Xin-Mei / Huang, Xi-Yang / Yuan, Yuan / Lu, Yong-Bin / Tang, Hui

    Mitochondrial DNA. Part B, Resources

    2024  Volume 9, Issue 3, Page(s) 411–414

    Abstract: ... Hemiboea ... ...

    Abstract Hemiboea pterocaulis
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2294890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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