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  1. Article ; Online: Comparison of Modified NUTRIC, NRS-2002, and MUST Scores in Iranian Critically Ill Patients Admitted to Intensive Care Units: A Prospective Cohort Study.

    Majari, Katrin / Imani, Hossein / Hosseini, Saeed / Amirsavadkouhi, Ali / Ardehali, Seyed Hossein / Khalooeifard, Razieh

    JPEN. Journal of parenteral and enteral nutrition

    2020  Volume 45, Issue 7, Page(s) 1504–1513

    Abstract: Background: There are no data on the validity of the modified Nutrition Risk in the Critically Ill (m-NUTRIC)-score and Nutritional Risk Screening 2002 (NRS-2002)-score in Iranian intensive care unit (ICU) patients. The Malnutrition Universal Screening ... ...

    Abstract Background: There are no data on the validity of the modified Nutrition Risk in the Critically Ill (m-NUTRIC)-score and Nutritional Risk Screening 2002 (NRS-2002)-score in Iranian intensive care unit (ICU) patients. The Malnutrition Universal Screening Tool (MUST) is still used in most Iranian ICUs. Our goal was to test the validity of these tools in the Iranian ICU population.
    Methods: The association between nutrition risk scores and outcomes (longer length of stay [LOS], prolonged mechanical ventilation [MV], and 28-day mortality) was assessed using the multivariable logistic regression. The performance of nutrition risk tools to predict 28-day mortality was assessed using the receiver operating characteristic curve. A logistic regression model was used to test the interaction between nutrition risk category, energy adequacy, and 28-day mortality.
    Results: Four hundred forty patients were included. Both the m-NUTRIC and NRS-2002 scores were significantly associated with all 3 outcomes (all P < .001). However, no significant association was identified between the MUST and all 3 outcomes (P > .05). The area under the curve for predicting 28-day mortality was 0.806 (95% CI, 0.756-0.851), 0.695 (95% CI, 0.632-0.752), and 0.551 (95% CI, 0.483-0.612) for m-NUTRIC, NRS-2002, and MUST, respectively. Greater energy adequacy was associated with a lower 28-day mortality rate in patients with high m-NUTRIC but not in those with low m-NUTRIC score (P interaction = .015).
    Conclusion: In the Iranian ICU population, the m-NUTRIC score may be a valid tool for identifying patients who would benefit from more aggressive nutrition therapy.
    MeSH term(s) Critical Illness ; Humans ; Intensive Care Units ; Iran/epidemiology ; Malnutrition/diagnosis ; Malnutrition/epidemiology ; Nutrition Assessment ; Nutritional Status ; Prospective Studies ; Risk Assessment
    Language English
    Publishing date 2020-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800861-9
    ISSN 1941-2444 ; 0148-6071
    ISSN (online) 1941-2444
    ISSN 0148-6071
    DOI 10.1002/jpen.2031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Effects of Morphine and Fentanyl on Patients with COVID-19.

    Amirsavadkouhi, Ali / Shahrami, Reza / Zadeh, Nadia Mohammad / Ilkhani, Saba / Mirtajani, Seyed Bashir / Salimi, Vahid / Mahjoubifard, Maziar / Jahangirifard, Alireza

    Tanaffos

    2021  Volume 20, Issue 2, Page(s) 164–171

    Abstract: Background: Sustained inflammation has been observed in the majority of severe COVID-19 cases. The impact of choice of opioid on perioperative inflammatory processes has not been assessed in the clinical setting.: Materials and methods: Patients with ...

    Abstract Background: Sustained inflammation has been observed in the majority of severe COVID-19 cases. The impact of choice of opioid on perioperative inflammatory processes has not been assessed in the clinical setting.
    Materials and methods: Patients with novel coronavirus (COVID-19) who referred to Masih Daneshvari and Noor-Afshar Hospitals in Tehran were included in the study after providing full explanations and obtaining written consent. Patients were then randomly divided into three groups: morphine, fentanyl and control. Patients in the morphine group received 3 mg of morphine intravenously every 6 hours for 5 days, whereas in the fentanyl group, 1.5 mcg / kg / h of fentanyl was infused for 2 hours on 5 consecutive days. The results were evaluated based on the design of the questionnaire and its completion using t-test and SPSS25 software.
    Results: A total of 127 participants responded to the survey between 20 April and 20 June 2020, of whom 90 (70.86%) with the average age 65.2 years, provided complete data on variables included in the present analyses. 53 (58.33%) of all individuals were men and 37 (41.12%) were women. Accordingly, 22 (24.4%) patients had a history of hypertension. However, diabetes with 16 (17.77%) cases and kidney diseases with 12 (13.33%), were the next most common underlying diseases. Evaluation of patients' clinical, laboratory and inflammatory conditions at different time intervals in both fentanyl and morphine groups did not show significant changes between these groups and the patients in the control one.
    Conclusion: The results of this study did not show any significant change in the use of fentanyl and morphine compared to patients with COVID 19. This may be due to the use of these drugs in the viral phase of the disease. The use of morphine and fentanyl in the viral phase of COVID 19 disease do not show significant benefits.
    Language English
    Publishing date 2021-12-08
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of the Cardio First Angel™ device on CPR indices: a randomized controlled clinical trial.

    Vahedian-Azimi, Amir / Hajiesmaeili, Mohammadreza / Amirsavadkouhi, Ali / Jamaati, Hamidreza / Izadi, Morteza / Madani, Seyed J / Hashemian, Seyed M R / Miller, Andrew C

    Critical care (London, England)

    2016  Volume 20, Issue 1, Page(s) 147

    Abstract: Background: A number of cardiopulmonary resuscitation (CPR) adjunct devices have been developed to improve the consistency and quality of manual chest compressions. We investigated whether a CPR feedback device would improve CPR quality and consistency, ...

    Abstract Background: A number of cardiopulmonary resuscitation (CPR) adjunct devices have been developed to improve the consistency and quality of manual chest compressions. We investigated whether a CPR feedback device would improve CPR quality and consistency, as well as patient survival.
    Methods: We conducted a randomized controlled study of patients undergoing CPR for cardiac arrest in the mixed medical-surgical intensive care units of four academic teaching hospitals. Patients were randomized to receive either standard manual CPR or CPR using the Cardio First Angel™ CPR feedback device. Recorded variables included guideline adherence, CPR quality, return of spontaneous circulation (ROSC) rates, and CPR-associated morbidity.
    Results: A total of 229 subjects were randomized; 149 were excluded; and 80 were included. Patient demographics were similar. Adherence to published CPR guidelines and CPR quality was significantly improved in the intervention group (p < 0.0001), as were ROSC rates (72 % vs. 35 %; p = 0.001). A significant decrease was observed in rib fractures (57 % vs. 85 %; p = 0.02), but not sternum fractures (5 % vs. 17 %; p = 0.15).
    Conclusions: Use of the Cardio First Angel™ CPR feedback device improved adherence to published CPR guidelines and CPR quality, and it was associated with increased rates of ROSC. A decrease in rib but not sternum fractures was observed with device use. Further independent prospective validation is warranted to determine if these results are reproducible in other acute care settings.
    Trial registration: ClinicalTrials.gov identifier: NCT02394977 . Registered on 5 Mar 2015.
    MeSH term(s) Aged ; Cardiopulmonary Resuscitation/instrumentation ; Cardiopulmonary Resuscitation/methods ; Cardiopulmonary Resuscitation/standards ; Equipment Design/standards ; Female ; Heart Arrest/mortality ; Humans ; Male ; Middle Aged ; Prospective Studies ; Survival Analysis
    Language English
    Publishing date 2016-05-17
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/s13054-016-1296-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: An Iranian Consensus Document for Nutrition in Critically Ill Patients, Recommendations and Initial Steps toward Regional Guidelines.

    Hashemian, Seyed Mohammadreza / Martindale, Robert G / Jamaati, Hamidreza / Amirsavadkouhi, Ali / Mahmudi Azer, Salahaddin / Shadnoush, Mahdi / Ardehali, Seyed Hossein / Najafi, Atabak / Ahmadi, Arezoo / Seyyedi, Seyyed Reza / Mahmoodpoor, Ata / Moradi, Omid / Abbasi, Saeed / Hosseini, Saeed / Shahrami, Reza / Abdi, Saeed / Sepehri, Zahra / Omranirad, Babak / Mohajerani, Seyed Amir /
    Rohani, Pejman / Sayyari, Aliakbar / Imani, Hossein / Velayati, Ali Akbar

    Tanaffos

    2017  Volume 16, Issue 2, Page(s) 89–98

    Language English
    Publishing date 2017-12-12
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
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  5. Article: Invasive candidiasis in intensive care unit; consensus statement from an Iranian panel of experts, July 2013.

    Ahmadi, Arezoo / Ardehali, Seyed Hossein / Beigmohammadi, Mohammad Taghi / Hajiabdolbaghi, Mahboubeh / Hashemian, Seyed Mohammad Reza / Kouchek, Mehran / Majidpour, Ali / Mokhtari, Majid / Moghaddam, Omid Moradi / Najafi, Atabak / Nejat, Reza / Niakan, Mohammad / Lotfi, Amir Hossein / Amirsavadkouhi, Ali / Shirazian, Farzad / Tabarsi, Payam / Taher, Mahshid Talebi / Torabi-Nami, Mohammad

    JRSM open

    2014  Volume 5, Issue 3, Page(s) 2042533313517689

    Abstract: Invasive candidiasis (IC) is associated with high mortality in intensive care unit (ICU) patients. Timely diagnosis of this potentially fatal condition remains a challenge; on the other hand, the criteria for initiating empirical antifungal therapy in ... ...

    Abstract Invasive candidiasis (IC) is associated with high mortality in intensive care unit (ICU) patients. Timely diagnosis of this potentially fatal condition remains a challenge; on the other hand, the criteria for initiating empirical antifungal therapy in critically ill patients are not well defined in different patient population and ICU settings. Alongside the international guidelines, reaching regional and local consensus on diagnosis and management of IC in ICU setting is essential. This report summarizes our present status of IC management in ICU, considered by a group of Iranian experts in the fields of intensive care and infectious diseases. A round table of 17 experts was held to review the available data and discuss the optimal treatment strategies for IC in critical care setting. Comparative published data on the management of IC were analytically reviewed and the commonly asked questions about the management of IC in ICU were isolated. These questions were interactively discussed by the panel and audience responses were taken to consolidate point-to-point agreement with the panel arriving at consensus in many instances. The responses indicated that patients' risk stratification, clinical discretion, fungal diagnostic techniques and the empirical therapy for IC are likely to save more patients. Treatment options were recommended to be based on the disease severity, prior azole exposure, and the presence of suspected azole-resistant Candida species. This report was reviewed, edited and discussed by all participants to include further evidence-based insights. The panel expects such endorsed recommendations to be soon formulated for implementation across the country.
    Language English
    Publishing date 2014-02-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2762955-7
    ISSN 2054-2704
    ISSN 2054-2704
    DOI 10.1177/2042533313517689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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