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  1. Book ; Online ; E-Book: The Pharmacological Potential of Cyanobacteria

    Lopes, Graciliana / Silva, Marisa / Vasconcelos, Vitor

    2022  

    Author's details edited by Graciliana Lopes, Marisa Silva and Vitor Vasconcelos
    Keywords Marine pharmacology
    Subject code 615.3
    Language English
    Size 1 online resource (358 pages)
    Publisher Academic Press
    Publishing place London, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-821492-9 ; 9780128214916 ; 978-0-12-821492-3 ; 0128214910
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Selected Papers from XVI MaNaPro and XI ECMNP

    Vasconcelos, Vítor / Vasconcelos, Vítor / Gaudencio, Susana P / Pedrosa, Rui

    2021  

    Keywords Technology: general issues ; marine-derived fungi ; secondary metabolites ; polyketides ; drimanes ; meroterpenoids ; cytotoxicity ; benthic cyanobacteria ; tropical mangrove ; Guadeloupe ; phylogenetic diversity ; chemical diversity ; molecular networking ; antimicrobial activity ; proteasome inhibition ; dolabellane ; secosteroids ; soft coral ; n/a ; marine natural products ; actinomycetes ; biofouling ; antifouling ; antibiofilm ; napyradiomycins ; hybrid isoprenoids ; drug discovery ; bioprospection ; Dysidea avara ; avarone/avarol ; redox-active compounds ; quinones and hydroquinones ; dioxothiazinoquinone ; Schistosoma mansoni ; Plasmodium falciparum ; Leishmania spp ; 3D-SAR analysis ; DFT studies ; PhenoTarget approach ; MRMS ; protein-ligand complex ; polycarpine ; holothurian ; diatom ; anti-fouling compounds ; saponins ; triterpene glycosides ; mass spectrometry ; Antarctica ; ascidian ; microbiome ; microbial diversity ; palmerolide A ; co-occurrence ; porphyrinoids ; annelida ; marine bioproducts ; HPLC-DAD ; toxicity ; photosensitizers ; chirality ; configurational analysis ; distance geometry ; NMR spectroscopy ; NOE data ; residual dipolar couplings ; Sarcophyton cherbonnieri ; cembranoid ; anti-inflammatory activity ; elastase release ; superoxide anion generation ; osteoarthritis ; amentadione ; preclinical osteoarthritis models ; marine compounds ; Cystoseira usneoides ; inflammation ; mineralization ; chondrocytes ; synoviocytes ; cartilage explants
    Size 1 electronic resource (214 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021291399
    ISBN 9783036506432 ; 3036506438
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Marine natural products and obesity

    Urbatzka, Ralph / Vasconcelos, Vítor

    (Marine drugs. Special issue)

    2019  

    Author's details special issue editors Ralph Urbatzka, Vítor Vasconcelos
    Series title Marine drugs. Special issue
    Language English
    Size 1 Online-Ressource (ix, 181 Seiten), Illustrationen, Diagramme
    Publisher MDPI
    Publishing place Basel ; Beijing ; Wuhan ; Barcelona ; Belgrade
    Publishing country Switzerland
    Document type Book ; Online
    Note Reprint of articles from the special issue published online in the open access journal Marine Drugs (ISSN 1660-3397) from 2018 to 2019 (available at: https://www.mdpi.com/journal/marinedrugs/special_issues/marine_obesity ) ; Open Access
    HBZ-ID HT020138320
    ISBN 978-3-03921-192-0 ; 9783039211913 ; 3-03921-192-7 ; 3039211919
    DOI 10.3390/books978-3-03921-192-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Marine Natural Products and Obesity

    Urbatzka, Ralph / Vasconcelos, Vítor

    2019  

    Abstract: Obesity and related co-morbidities are increasing worldwide and pose a serious health problem. Changes in lifestyle and diet would be the best remedies to fight obesity; however, many people will still rely on medical aid. Marine organisms have been ... ...

    Abstract Obesity and related co-morbidities are increasing worldwide and pose a serious health problem. Changes in lifestyle and diet would be the best remedies to fight obesity; however, many people will still rely on medical aid. Marine organisms have been prolific in the production of bioactive compounds for many diseases, e.g., cancer, and promise to be an excellent source for natural-derived molecules and novel nutraceuticals. Bioactive compounds with beneficial activities towards obesity have been described from diverse marine organism including marine algae, bacteria, sponges, fungi, crustaceans or fish. This Special Issue will highlight the progress in the following topics: Bioactive compounds for the treatment of obesity and obesity-related co-morbidities (diabetes, fatty liver, hyperlipidemia) from marine organisms; the isolation of novel compounds, the bioactivity screening of marine organisms and the elucidation of molecular mode of action of marine bioactive compounds
    Keywords Medicine (General) ; Internal medicine
    Size 1 electronic resource (194 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note eng ; Open Access
    HBZ-ID HT020307392
    ISBN 9783039211913 ; 9783039211920 ; 3039211919 ; 3039211927
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Adaptive foraging of pollinators fosters gradual tipping under resource competition and rapid environmental change.

    Terpstra, Sjoerd / Marquitti, Flávia M D / Vasconcelos, Vítor V

    PLoS computational biology

    2024  Volume 20, Issue 1, Page(s) e1011762

    Abstract: Plant and pollinator communities are vital for transnational food chains. Like many natural systems, they are affected by global change: rapidly deteriorating conditions threaten their numbers. Previous theoretical studies identified the potential for ... ...

    Abstract Plant and pollinator communities are vital for transnational food chains. Like many natural systems, they are affected by global change: rapidly deteriorating conditions threaten their numbers. Previous theoretical studies identified the potential for community-wide collapse above critical levels of environmental stressors-so-called bifurcation-induced tipping points. Fortunately, even as conditions deteriorate, individuals have some adaptive capacity, potentially increasing the boundary for a safe operating space where changes in ecological processes are reversible. Our study considers this adaptive capacity of pollinators to resource availability and identifies a new threat to disturbed pollinator communities. We model the adaptive foraging of pollinators in changing environments. Pollinator's adaptive foraging alters the dynamical responses of species, to the advantage of some-typically generalists-and the disadvantage of others, with systematic non-linear and non-monotonic effects on the abundance of particular species. We show that, in addition to the extent of environmental stress, the pace of change of environmental stress can also lead to the early collapse of both adaptive and nonadaptive pollinator communities. Specifically, perturbed communities exhibit rate-induced tipping points at stress levels within the safe boundary defined for constant stressors. With adaptive foraging, tipping is a more asynchronous collapse of species compared to nonadaptive pollinator communities, meaning that not all pollinator species reach a tipping event simultaneously. These results suggest that it is essential to consider the adaptive capacity of pollinator communities for monitoring and conservation. Both the extent and the rate of stress change relative to the ability of communities to recover are critical environmental boundaries.
    MeSH term(s) Humans ; Pollination/physiology ; Models, Biological ; Models, Theoretical ; Plants ; Food Chain
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2193340-6
    ISSN 1553-7358 ; 1553-734X
    ISSN (online) 1553-7358
    ISSN 1553-734X
    DOI 10.1371/journal.pcbi.1011762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Legal Aspects of Microalgae in the European Food Sector.

    Cruz, José Diogo / Vasconcelos, Vitor

    Foods (Basel, Switzerland)

    2023  Volume 13, Issue 1

    Abstract: The interest in microalgae as food in Europe is growing due to its remarkable features that can foster a sustainable economy. The lack of tradition on their use among Europeans is changing and a demand for more sustainable products is increasing. The ... ...

    Abstract The interest in microalgae as food in Europe is growing due to its remarkable features that can foster a sustainable economy. The lack of tradition on their use among Europeans is changing and a demand for more sustainable products is increasing. The legal framework from the microalgae stakeholders' point of view has been consistently identified as a bottleneck, regardless of its nutritional value and potential to provide added-value metabolites. Microalgae-based products have been mostly consumed as food supplements, which are characterized by some general uncertainty with regards to food security of products sourced from non-European countries. The novel foods regulation is a landmark in Europe's food law defining the conditions in which a new type of food can be commercialized. Currently, a more simplified and centralized version is in place, and around eleven microalgae-based products are on the market; however, more than half are represented by
    Language English
    Publishing date 2023-12-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13010124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reduction of neutral lipid reservoirs, bioconversion and untargeted metabolomics reveal distinct roles for vitamin K isoforms on lipid metabolism.

    Silva, Natália Gonçalves / Preto, Marco / Vasconcelos, Vitor / Urbatzka, Ralph

    Food & function

    2024  Volume 15, Issue 4, Page(s) 2170–2180

    Abstract: Vitamin K isoforms are known as co-factors for the synthesis of blood-clotting proteins, but several other bioactivities were reported. In this work, we isolated a vitamin K1-analogue (OH-PhQ) from the ... ...

    Abstract Vitamin K isoforms are known as co-factors for the synthesis of blood-clotting proteins, but several other bioactivities were reported. In this work, we isolated a vitamin K1-analogue (OH-PhQ) from the cyanobacterium
    MeSH term(s) Animals ; Vitamin K ; Zebrafish/metabolism ; Lipid Metabolism ; Vitamin K 1/metabolism ; Protein Isoforms/metabolism ; Lipids ; Vitamin K 2 ; Vitamin K 3
    Chemical Substances Vitamin K (12001-79-5) ; Vitamin K 1 (84-80-0) ; Protein Isoforms ; Lipids ; Vitamin K 2 (11032-49-8) ; Vitamin K 3 (723JX6CXY5)
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo02915h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7872: Show issues

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  8. Article ; Online: Description of Pseudocalidococcus azoricus gen. sp. nov. (Thermosynechococcaceae, Cyanobacteria), a Rare but Widely Distributed Coccoid Cyanobacteria

    Rúben Luz / Rita Cordeiro / Jan Kaštovský / Amélia Fonseca / Ralph Urbatzka / Vitor Vasconcelos / Vítor Gonçalves

    Diversity, Vol 15, Iss 12, p

    2023  Volume 1157

    Abstract: Coccoid cyanobacteria represent an important part of cyanobacterial freshwater diversity, with many studied strains in public databases identified as Synechococcus . This is a diverse genus, both morphologically and ecologically, with a global ... ...

    Abstract Coccoid cyanobacteria represent an important part of cyanobacterial freshwater diversity, with many studied strains in public databases identified as Synechococcus . This is a diverse genus, both morphologically and ecologically, with a global distribution. However, many of the so-called Synechococcus -like cyanobacteria strains could represent several independent genera that require further studies. In this work, four strains of a Synechococcus -like cyanobacteria isolated from freshwater lakes and terrestrial atmophytic habitats on São Miguel and Flores Islands (Azores archipelago) were studied genetically using the 16S rRNA and 16S–23S rRNA ITS, morphologically with light and transmission electron microscopy, and ecologically. A draft genome was produced from the reference strain by Illumina sequencing, which allowed a more complete phylogenetic study and a deeper taxonomic analysis, revealing a divergent phylogenetic evolution and low ANI and AAI values (69.4% and 66.3%, respectively) to Thermosynechococcus , the closest phylogenetic genus. Although morphologically similar to Synechococcus , the 16S rRNA and genome phylogenetic analysis placed the studied strains in a clade sister to Thermosynechococcus , inside the Thermosynechococcaceae. Thus, Pseudocalidococcus azoricus gen. sp. nov. is described as a new coccoid freshwater genus and species from the Azores archipelago. A detailed comparison with similar morphological taxa is provided, supporting the separation of the new genus. The 16S rRNA with a high genetic similarity to other strains from several continents identified as Synechococcus sp. suggests that the new genus probably has a worldwide distribution. Future studies should be performed to clarify the taxonomic identity of those strains.
    Keywords AAI ; ANI ; Azores ; coccoid cyanobacteria ; DDH ; genome ; Biology (General) ; QH301-705.5
    Subject code 590
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Effect of Hydrogen Peroxide on Cyanobacterial Biofilms.

    Romeu, Maria João / Morais, João / Vasconcelos, Vítor / Mergulhão, Filipe

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: Although a range of disinfecting formulations is commercially available, hydrogen peroxide is one of the safest chemical agents used for disinfection in aquatic environments. However, its effect on cyanobacterial biofilms is poorly investigated. In this ... ...

    Abstract Although a range of disinfecting formulations is commercially available, hydrogen peroxide is one of the safest chemical agents used for disinfection in aquatic environments. However, its effect on cyanobacterial biofilms is poorly investigated. In this work, biofilm formation by two filamentous cyanobacterial strains was evaluated over seven weeks on two surfaces commonly used in marine environments: glass and silicone-based paint (Sil-Ref) under controlled hydrodynamic conditions. After seven weeks, the biofilms were treated with a solution of hydrogen peroxide (H
    Language English
    Publishing date 2023-09-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12091450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Exploring the Bioactive Potential of

    Oliveira, Rui S / Preto, Marco / Santos, Germana / Silva, Ana Margarida / Vasconcelos, Vitor / Martins, Rosário

    Microorganisms

    2024  Volume 12, Issue 3

    Abstract: Addressing pressing health concerns, modern medical research seeks to identify new antimicrobials to combat drug resistance, novel molecules for cancer treatment, and antioxidants for inflammation-related diseases. ...

    Abstract Addressing pressing health concerns, modern medical research seeks to identify new antimicrobials to combat drug resistance, novel molecules for cancer treatment, and antioxidants for inflammation-related diseases.
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12030450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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