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  1. Book ; Online ; E-Book: Challenges in cataract surgery

    Kim, Wan Soo / Kim, Kyeong Hwan

    principles and techniques for successful management

    2016  

    Language English
    Size 1 Online-Ressource (xiv, 128 Seiten)
    Publisher Springer
    Publishing place Berlin, Heidelberg
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019149080
    ISBN 978-3-662-46092-4 ; 9783662460917 ; 3-662-46092-0 ; 3662460912
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Highly conductive, conformable ionic laser-induced graphene electrodes for flexible iontronic devices.

    Kim, So Young / Kim, Ji Hong / Kim, Kyeong Nam / Oh, Hayoung / Myung, Sung / Kim, Do Hwan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4599

    Abstract: Iontronic devices, recognized for user-friendly soft electronics, establish an electrical double layer (EDL) at the interface between ion gels and electrodes, significantly influencing device performance. Despite extensive research on ion gels and ... ...

    Abstract Iontronic devices, recognized for user-friendly soft electronics, establish an electrical double layer (EDL) at the interface between ion gels and electrodes, significantly influencing device performance. Despite extensive research on ion gels and diverse electrode materials, achieving a stable interfacial formation remains a persistent challenge. In this work, we report a solution to address this challenge by employing CO
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55082-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prognostic factors for tracheostomy early decannulation in acquired brain injury patients.

    Lee, Jong Hwa / Kim, Sang Beom / Lee, Kyeong Woo / Kim, Soo Hwan

    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation

    2024  Volume 47, Issue 2, Page(s) 97–102

    Abstract: After severe brain injuries, a tracheostomy tube is usually inserted for respiratory support. This study aimed to clarify the prognostic factors for tracheostomy early decannulation in patients with acquired brain injuries. We retrospectively reviewed ... ...

    Abstract After severe brain injuries, a tracheostomy tube is usually inserted for respiratory support. This study aimed to clarify the prognostic factors for tracheostomy early decannulation in patients with acquired brain injuries. We retrospectively reviewed the medical records of inpatients with acquired brain injuries who underwent successful tracheostomy decannulation between March 2021 and June 2022. Fifty-six patients were included; median age was 68 (59-72) years; 28 (50%) were men; 28 (50%) underwent tracheostomy due to stroke. The median time to decannulation was 47 days. The patients were divided into the early and the late decannulation groups based on the median time, and compared. In univariate analysis, the early decannulation group had a higher BMI, peak cough flow, and acquired brain injuries due to trauma, and a lower penetration-aspiration scale score, duration of antibiotic use, and duration of oxygen use. Multivariate Cox regression analysis revealed that a higher initial peak cough flow [hazard ratio (HR) 1.142; 95% confidence interval (CI) 0.912-0.954; P  < 0.001] and lower duration of oxygen use (HR 0.930; 95% CI 0.502-0.864; P  = 0.016) were independent factors for early tracheostomy decannulation, with each unit increase in peak cough flow corresponding to a 14.2% increase and each additional day of duration of oxygen use corresponding to a 7.0% decrease in the likelihood of early decannulation. In conclusion, key prognostic factors for early tracheostomy decannulation were identified as the initial cough strength and duration of oxygen use. These results could play important role in decannulation plans for patients with tracheostomy tube.
    MeSH term(s) Humans ; Tracheostomy ; Male ; Female ; Middle Aged ; Aged ; Retrospective Studies ; Prognosis ; Brain Injuries/rehabilitation ; Device Removal ; Time Factors
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 533323-4
    ISSN 1473-5660 ; 0342-5282
    ISSN (online) 1473-5660
    ISSN 0342-5282
    DOI 10.1097/MRR.0000000000000618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Arabidopsis thaliana ubiquitin-associated protein 2 (AtUAP2) functions as an E4 ubiquitin factor and negatively modulates dehydration stress response.

    Park, Cho-Rong / Min, Ji-Hee / Gong, Ying / Sang, Hyunkyu / Lee, Kyeong-Hwan / Kim, Cheol Soo

    Plant molecular biology

    2024  Volume 114, Issue 1, Page(s) 13

    Abstract: E4, a ubiquitin (Ub) chain assembly factor and post-translational modification protein, plays a key role in the regulation of multiple cellular functions in plants during biotic or abiotic stress. We have more recently reported that E4 factor AtUAP1 is a ...

    Abstract E4, a ubiquitin (Ub) chain assembly factor and post-translational modification protein, plays a key role in the regulation of multiple cellular functions in plants during biotic or abiotic stress. We have more recently reported that E4 factor AtUAP1 is a negative regulator of the osmotic stress response and enhances the multi-Ub chain assembly of E3 ligase Arabidopsis thaliana RING Zinc Finger 1 (AtRZF1). To further investigate the function of other E4 Ub factors in osmotic stress, we isolated AtUAP2, an AtUAP1 homolog, which interacted with AtRZF1, using pull-down assay and bimolecular fluorescence complementation analysis. AtUAP2, a Ub-associated motif-containing protein, interacts with oligo-Ub
    MeSH term(s) Ubiquitin ; Arabidopsis ; Dehydration ; Protein Processing, Post-Translational ; Ubiquitination
    Chemical Substances Ubiquitin
    Language English
    Publishing date 2024-02-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 778032-1
    ISSN 1573-5028 ; 0167-4412
    ISSN (online) 1573-5028
    ISSN 0167-4412
    DOI 10.1007/s11103-024-01419-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Recent advances in the application of magnetic materials for the management of perfluoroalkyl substances in aqueous phases.

    Kang, Kyeong Hwan / Saifuddin, Md / Chon, Kangmin / Bae, Sungjun / Kim, Young Mo

    Chemosphere

    2024  Volume 352, Page(s) 141522

    Abstract: Perfluoroalkyl substances (PFASs) are a class of artificially synthesised organic compounds extensively used in both industrial and consumer products owing to their unique characteristics. However, their persistence in the environment and potential risk ... ...

    Abstract Perfluoroalkyl substances (PFASs) are a class of artificially synthesised organic compounds extensively used in both industrial and consumer products owing to their unique characteristics. However, their persistence in the environment and potential risk to health have raised serious global concerns. Therefore, developing effective techniques to identify, eliminate, and degrade these pollutants in water are crucial. Owing to their high surface area, magnetic responsiveness, redox sensitivity, and ease of separation, magnetic materials have been considered for the treatment of PFASs from water in recent years. This review provides a comprehensive overview of the recent use of magnetic materials for the detection, removal, and degradation of PFASs in aqueous solutions. First, the use of magnetic materials for sensitive and precise detection of PFASs is addressed. Second, the adsorption of PFASs using magnetic materials is discussed. Several magnetic materials, including iron oxides, ferrites, and magnetic carbon composites, have been explored as efficient adsorbents for PFASs removal from water. Surface modification, functionalization, and composite fabrication have been employed to improve the adsorption effectiveness and selectivity of magnetic materials for PFASs. The final section of this review focuses on the advanced oxidation for PFASs using magnetic materials. This review suggests that magnetic materials have demonstrated considerable potential for use in various environmental remediation applications, as well as in the treatment of PFASs-contaminated water.
    MeSH term(s) Fluorocarbons/analysis ; Water ; Environmental Restoration and Remediation ; Environmental Pollutants/analysis ; Magnetic Phenomena ; Water Pollutants, Chemical/analysis
    Chemical Substances Fluorocarbons ; Water (059QF0KO0R) ; Environmental Pollutants ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mitigation of N

    Hwan Kang, Kyeong / Yang, Minseok / Raza, Shahbaz / Son, Heejong / Park, Young-Kwon / Wang, Jinhua / Kim, Young Mo

    Chemosphere

    2023  Volume 335, Page(s) 139114

    Abstract: The effects of an external carbon source (C-source) on the mitigation of ... ...

    Abstract The effects of an external carbon source (C-source) on the mitigation of N
    MeSH term(s) Sewage ; Denitrification ; Water Pollutants, Chemical ; Bioreactors ; Carbon ; Fatty Acids, Volatile ; Nitrogen
    Chemical Substances Sewage ; Water Pollutants, Chemical ; Carbon (7440-44-0) ; Fatty Acids, Volatile ; Nitrogen (N762921K75)
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.139114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Retrospective Analysis of Clinical Feature in Trigeminal Neuralgia.

    Hong, Ji Hee / Lee, Jae Yoon / Kim, Seung Ju / Seo, Kyeong Hwan

    Pain physician

    2023  Volume 26, Issue 1, Page(s) 39–44

    Abstract: Background: Trigeminal neuralgia (TN) is usually established using characteristic clinical features such as sudden, severe, and unilateral facial pain. Studies about diverse clinical features and epidemiologic data of TN have been reported previously; ... ...

    Abstract Background: Trigeminal neuralgia (TN) is usually established using characteristic clinical features such as sudden, severe, and unilateral facial pain. Studies about diverse clinical features and epidemiologic data of TN have been reported previously; however, most of the previous studies have evaluated in and focused on Caucasian and Western populations.
    Objectives: The purpose of this study was to evaluate diverse clinical features, currently applied types of treatment, and brain imaging studies in patients with TN in a Korean population.
    Study design: Retrospective analysis.
    Setting: An interventional pain management practice in South Korea.
    Methods: Patients with a primary diagnosis of TN were identified using Clinical Data Warehouse v 2.5 (CDW, Planit Healthcare, Seoul, Korea) using the key words "trigeminal neuralgia and G50.0 (International classification of disease 10 code)."
    Results: TN occurred predominantly between the fifth and seventh decades of life, with female predominance. The V3 division and unilateral right-side involvement were the most common affected region. An electric shock like sensation and the intraoral side (teeth and gingiva) were the most common pain description and location, respectively. Normal brain imaging studies and vascular compression on the trigeminal nerve were observed in 92 (64.7%) and 36 (25%) patients, respectively. The superior cerebellar artery was the most common offending vessel (19;13.3%). Monotherapy with carbamazepine alone was the most common (91;37.7%), whereas radiofrequency thermoablation was the most common invasive treatment.
    Limitations: The results of this study were based on data on TN patients from a single center. The generalizability of the findings to the Korean population is thus limited.
    Conclusion: There is little difference between Korean and other Asian patients with TN in their demographic and clinical characteristics.
    MeSH term(s) Humans ; Female ; Male ; Trigeminal Neuralgia/therapy ; Trigeminal Neuralgia/diagnosis ; Retrospective Studies ; Treatment Outcome ; Trigeminal Nerve ; Pain Management/methods
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2146393-1
    ISSN 2150-1149 ; 1533-3159
    ISSN (online) 2150-1149
    ISSN 1533-3159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Preoperative Serum Copeptin Can Predict Delayed Hyponatremia after Pituitary Surgery in the Absence of Arginine Vasopressin Deficiency.

    Kang, Ho / Park, Seung Shin / Kim, Yoo Hyung / Lim, Hwan Sub / Lee, Mi-Kyeong / Lee, Kyoung-Ryul / Kim, Jung Hee / Kim, Yong Hwy

    Endocrinology and metabolism (Seoul, Korea)

    2024  Volume 39, Issue 1, Page(s) 164–175

    Abstract: Backgruound: Delayed postoperative hyponatremia (DPH) is the most common cause of readmission after pituitary surgery. In this study, we aimed to evaluate the cutoff values of serum copeptin and determine the optimal timing for copeptin measurement for ... ...

    Abstract Backgruound: Delayed postoperative hyponatremia (DPH) is the most common cause of readmission after pituitary surgery. In this study, we aimed to evaluate the cutoff values of serum copeptin and determine the optimal timing for copeptin measurement for the prediction of the occurrence of DPH in patients who undergo endoscopic transsphenoidal approach (eTSA) surgery and tumor resection.
    Methods: This was a prospective observational study of 73 patients who underwent eTSA surgery for pituitary or stalk lesions. Copeptin levels were measured before surgery, 1 hour after extubation, and on postoperative days 1, 2, 7, and 90.
    Results: Among 73 patients, 23 patients (31.5%) developed DPH. The baseline ratio of copeptin to serum sodium level showed the highest predictive performance (area under the curve [AUROC], 0.699), and its optimal cutoff to maximize Youden's index was 2.5×10-11, with a sensitivity of 91.3% and negative predictive value of 92.0%. No significant predictors were identified for patients with transient arginine vasopressin (AVP) deficiency. However, for patients without transient AVP deficiency, the copeptin-to-urine osmolarity ratio at baseline demonstrated the highest predictive performance (AUROC, 0.725). An optimal cutoff of 6.5×10-12 maximized Youden's index, with a sensitivity of 92.9% and a negative predictive value of 94.1%.
    Conclusion: The occurrence of DPH can be predicted using baseline copeptin and its ratio with serum sodium or urine osmolarity only in patients without transient AVP deficiency after pituitary surgery.
    MeSH term(s) Humans ; Arginine ; Diabetes Insipidus, Neurogenic/complications ; Glycopeptides ; Hyponatremia/diagnosis ; Hyponatremia/etiology ; Pituitary Diseases ; Sodium
    Chemical Substances Arginine (94ZLA3W45F) ; copeptins ; Glycopeptides ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2024-01-03
    Publishing country Korea (South)
    Document type Observational Study ; Journal Article
    ZDB-ID 2802452-7
    ISSN 2093-5978 ; 2093-5978
    ISSN (online) 2093-5978
    ISSN 2093-5978
    DOI 10.3803/EnM.2023.1792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clinicopathologic significance of mismatch repair protein expression in endometrioid endometrial cancer.

    Kim, Mi-Kyung / So, Kyeong A / Chun, Yi-Kyeong / Kim, Yun Hwan / Lim, Kyung Taek / Lee, Ki Heon / Kim, Tae Jin

    Taiwanese journal of obstetrics & gynecology

    2023  Volume 62, Issue 5, Page(s) 724–728

    Abstract: Objective: To evaluate the association between mismatch repair (MMR) protein expression and clinico-pathologic outcomes in patients with endometrioid endometrial cancer (EC).: Materials and methods: A retrospective review of the clinico-pathologic ... ...

    Abstract Objective: To evaluate the association between mismatch repair (MMR) protein expression and clinico-pathologic outcomes in patients with endometrioid endometrial cancer (EC).
    Materials and methods: A retrospective review of the clinico-pathologic outcomes was performed on patients who were diagnosed with EC and had results of MMR protein immunohistochemistry. MMR-deficient (MMR-d) was defined as absence of expression in any of the 4 MMR proteins (MLH1, MSH2, MSH6, and PMS2). Demographics, pathologic variables, and survival outcomes were compared according to the MMR status.
    Results: A total of 193 EC patients with available MMR expression data were included, of whom 163 patients had endometrioid type EC. Overall, 44 patients (27.0%) were classified as MMR-d. Compared with MMR-proficient (MMR-p) group, MMR-d group was associated with more frequent lymphovascular space invasion (LVSI, p = 0.001). MMR-d was also related with higher risk of lymph node (LN) metastasis in endometrioid type EC (p = 0.008), especially para-aortic LN metastasis. During the median follow-up period of 19.1 months (1-44.5), MMR-d group, especially MLH1/PMS2 subgroup, showed a tendency of reduced PFS (p = 0.036 and p = 0.008, respectively). On Cox regression analysis, however, LN metastasis remained as the only independent risk factor for PFS (p = 0.004) in endometrioid EC, and MLH1/PMS2 loss showed a marginally significant association (p = 0.054).
    Conclusion: Our findings of the associations between MMR deficiency and poor prognostic factors, such as LVSI and LN metastasis, may suggest the prognostic value of MMR status in EC and need further prospective validation studies.
    MeSH term(s) Humans ; Female ; DNA Mismatch Repair ; Mismatch Repair Endonuclease PMS2 ; Carcinoma, Endometrioid ; Lymph Nodes ; Lymphatic Metastasis
    Chemical Substances Mismatch Repair Endonuclease PMS2 (EC 3.6.1.3)
    Language English
    Publishing date 2023-03-16
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ZDB-ID 2202946-1
    ISSN 1875-6263 ; 1875-6263
    ISSN (online) 1875-6263
    ISSN 1875-6263
    DOI 10.1016/j.tjog.2023.07.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of the problem-solving performance of ChatGPT-3.5, ChatGPT-4, Bing Chat, and Bard for the Korean emergency medicine board examination question bank.

    Lee, Go Un / Hong, Dae Young / Kim, Sin Young / Kim, Jong Won / Lee, Young Hwan / Park, Sang O / Lee, Kyeong Ryong

    Medicine

    2024  Volume 103, Issue 9, Page(s) e37325

    Abstract: Large language models (LLMs) have been deployed in diverse fields, and the potential for their application in medicine has been explored through numerous studies. This study aimed to evaluate and compare the performance of ChatGPT-3.5, ChatGPT-4, Bing ... ...

    Abstract Large language models (LLMs) have been deployed in diverse fields, and the potential for their application in medicine has been explored through numerous studies. This study aimed to evaluate and compare the performance of ChatGPT-3.5, ChatGPT-4, Bing Chat, and Bard for the Emergency Medicine Board Examination question bank in the Korean language. Of the 2353 questions in the question bank, 150 questions were randomly selected, and 27 containing figures were excluded. Questions that required abilities such as analysis, creative thinking, evaluation, and synthesis were classified as higher-order questions, and those that required only recall, memory, and factual information in response were classified as lower-order questions. The answers and explanations obtained by inputting the 123 questions into the LLMs were analyzed and compared. ChatGPT-4 (75.6%) and Bing Chat (70.7%) showed higher correct response rates than ChatGPT-3.5 (56.9%) and Bard (51.2%). ChatGPT-4 showed the highest correct response rate for the higher-order questions at 76.5%, and Bard and Bing Chat showed the highest rate for the lower-order questions at 71.4%. The appropriateness of the explanation for the answer was significantly higher for ChatGPT-4 and Bing Chat than for ChatGPT-3.5 and Bard (75.6%, 68.3%, 52.8%, and 50.4%, respectively). ChatGPT-4 and Bing Chat outperformed ChatGPT-3.5 and Bard in answering a random selection of Emergency Medicine Board Examination questions in the Korean language.
    MeSH term(s) Emergency Medicine/education ; Language ; Republic of Korea ; Artificial Intelligence ; Educational Measurement
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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