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  1. AU=Berman Jonathan M
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  1. Artikel ; Online: [Titelangabe fehlt]

    Berman, Jonathan M

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2021  Band 193, Heft 24, Seite(n) E945–E947

    Titelübersetzung Quand le sentiment antivaccin mène à la violence : émeute antivaccination de 1885 à Montréal.
    Sprache Französisch
    Erscheinungsdatum 2021-12-01
    Erscheinungsland Canada
    Dokumenttyp Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.202820-f
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: When antivaccine sentiment turned violent: the Montréal Vaccine Riot of 1885.

    Berman, Jonathan M

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2021  Band 193, Heft 14, Seite(n) E490–E492

    Mesh-Begriff(e) Anti-Vaccination Movement/history ; History, 19th Century ; Humans ; Quebec ; Riots/history ; Smallpox Vaccine/history
    Chemische Substanzen Smallpox Vaccine
    Sprache Englisch
    Erscheinungsdatum 2021-03-28
    Erscheinungsland Canada
    Dokumenttyp Historical Article ; Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.202820
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Guiding Principles for Managed Care Arrangements for the Health of Newborns, Infants, Children, Adolescents and Young Adults.

    Carlson, Kenneth M / Berman, Suzanne K / Price, Jonathan

    Pediatrics

    2022  Band 150, Heft 2

    Abstract: Managed care arrangements are an approach to health care delivery in which the payer or other health care entity has policies that affect where care is delivered, what services are covered, and how payment is determined. When policies are intentionally ... ...

    Abstract Managed care arrangements are an approach to health care delivery in which the payer or other health care entity has policies that affect where care is delivered, what services are covered, and how payment is determined. When policies are intentionally designed, transparently administered, and continuously monitored, they are more likely to improve the population's utilization of services, access to quality primary and specialty care, and access to appropriate medications. When managed care arrangements are designed well, particularly within evolving payment models, health care can be delivered in a manner that supports the goals of the Quadruple Aim: to reduce per capita costs of health care, to improve the health of populations, to improve the experience of patients receiving care, and to improve the experience of those who are providing care. The American Academy of Pediatrics (AAP) urges payers and health care entities to use the key principles outlined in this statement when designing and implementing managed care arrangements and policies that cover newborn infants, infants, children, adolescents, and young adults to support the goal of improving the effectiveness of the health care delivery system for the pediatric population. The principles described in this statement are intended to complement those previously published in other AAP policies including "Principles of Child Health Care Financing," "Scope of Health Care Benefits for Children From Birth Through Age 26," "Patient- and Family-Centered Care and the Pediatrician's Role," and the "AAP Access Principles."
    Mesh-Begriff(e) Adolescent ; Adult ; Child ; Child Health Services ; Delivery of Health Care ; Family ; Healthcare Financing ; Humans ; Infant ; Infant, Newborn ; Managed Care Programs ; United States ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2022-07-31
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2022-058396
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Commentary on ethical dilemmas in the management of infants with enterocolitis totalis.

    Berman, Loren / Levy, Carly / Miller, Jonathan M

    Journal of pediatric surgery

    2021  Band 57, Heft 3, Seite(n) 337–338

    Abstract: This is a Commentary on the manuscript titled "Ethical Dilemmas in the Management of Infants with Necrotizing Enterocolitis Totalis" by Pennington E, Javid P, Mueller C, et al. ...

    Abstract This is a Commentary on the manuscript titled "Ethical Dilemmas in the Management of Infants with Necrotizing Enterocolitis Totalis" by Pennington E, Javid P, Mueller C, et al.
    Sprache Englisch
    Erscheinungsdatum 2021-09-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2021.09.037
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Positive associations matter: Microbial relationships drive tick microbiome composition.

    Fountain-Jones, Nicholas M / Khoo, Benedict S / Rau, Austin / Berman, Jesse D / Burton, Erin N / Oliver, Jonathan D

    Molecular ecology

    2023  Band 32, Heft 14, Seite(n) 4078–4092

    Abstract: Untangling how factors such as environment, host, associations among bacterial species and dispersal predict microbial composition is a fundamental challenge. In this study, we use complementary machine-learning approaches to quantify the relative role ... ...

    Abstract Untangling how factors such as environment, host, associations among bacterial species and dispersal predict microbial composition is a fundamental challenge. In this study, we use complementary machine-learning approaches to quantify the relative role of these factors in shaping microbiome variation of the blacklegged tick Ixodes scapularis. I. scapularis is the most important vector for Borrelia burgdorferi (the causative agent for Lyme disease) in the U.S. as well as a range of other important zoonotic pathogens. Yet the relative role of the interactions between pathogens and symbionts compared to other ecological forces is unknown. We found that positive associations between microbes where the occurrence of one microbe increases the probability of observing another, including between both pathogens and symbionts, was by far the most important factor shaping the tick microbiome. Microclimate and host factors played an important role for a subset of the tick microbiome including Borrelia (Borreliella) and Ralstonia, but for the majority of microbes, environmental and host variables were poor predictors at a regional scale. This study provides new hypotheses on how pathogens and symbionts might interact within tick species, as well as valuable predictions for how some taxa may respond to changing climate.
    Mesh-Begriff(e) Animals ; Lyme Disease/microbiology ; Ixodes/microbiology ; Borrelia burgdorferi/genetics ; Borrelia ; Microbiota/genetics
    Sprache Englisch
    Erscheinungsdatum 2023-05-12
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1126687-9
    ISSN 1365-294X ; 0962-1083
    ISSN (online) 1365-294X
    ISSN 0962-1083
    DOI 10.1111/mec.16985
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Epidemiology and economic burden of Von Hippel-Lindau Disease-associated central nervous system hemangioblastomas and pancreatic neuroendocrine tumors in the United States.

    Jonasch, Eric / Song, Yan / Freimark, Jonathan / Berman, Richard / Nguyen, Ha / Signorovitch, James / Sundaram, Murali

    Orphanet journal of rare diseases

    2024  Band 19, Heft 1, Seite(n) 73

    Abstract: Background: To date, real-world evidence around the clinical and economic burden related to von Hippel-Lindau (VHL) disease is limited. Therefore, this study characterized the prevalence, healthcare resource utilization (HRU), and economic burden of von ...

    Abstract Background: To date, real-world evidence around the clinical and economic burden related to von Hippel-Lindau (VHL) disease is limited. Therefore, this study characterized the prevalence, healthcare resource utilization (HRU), and economic burden of von Hippel-Lindau-associated central nervous system hemangioblastoma (VHL-CNS-Hb) and pancreatic neuroendocrine tumors (VHL-pNET) in the United States (US).
    Methods: Patients with VHL-CNS-Hb or VHL-pNET were identified from Optum's de-identified Clinformatics® Data Mart Database (2007-2020) and matched 1:5 to control patients without VHL disease or CNS-Hb/pNET. Prevalence rates of VHL-CNS-Hb and VHL-pNET (standardized by age and sex) in 2019 were estimated. HRU and healthcare costs (2020 US dollars) were compared between the VHL-CNS-Hb/VHL-pNET and control cohorts.
    Results: In 2019, US prevalence rates of VHL-CNS-Hb and VHL-pNET were estimated to be 1.12 cases per 100,000 (3,678 patients) and 0.12 cases per 100,000 (389 patients), respectively. Patients with VHL-CNS-Hb (N = 220) had more inpatient, outpatient, and emergency department visits and $49,645 higher annual healthcare costs than controls (N = 1,100). Patients with VHL-pNET (N = 20) had more inpatient and outpatient visits and $56,580 higher annual healthcare costs than controls (N = 100). Costs associated with surgical removal of CNS-Hb and pNET were particularly high.
    Conclusions: In this retrospective, claims-based study, both VHL-CNS-Hb and VHL-pNET were associated with substantial HRU and healthcare costs, particularly tumor reduction surgery-related costs. These findings provide important insight for healthcare payers regarding the expected real-world costs that enrollees with VHL-CNS-Hb and VHL-pNET may incur over the course of their disease.
    Mesh-Begriff(e) Humans ; von Hippel-Lindau Disease/complications ; Neuroendocrine Tumors/epidemiology ; Neuroendocrine Tumors/pathology ; Hemangioblastoma/epidemiology ; Financial Stress ; Retrospective Studies ; Central Nervous System/pathology ; Pancreatic Neoplasms/epidemiology ; Pancreatic Neoplasms/pathology ; Neuroectodermal Tumors, Primitive
    Sprache Englisch
    Erscheinungsdatum 2024-02-16
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2225857-7
    ISSN 1750-1172 ; 1750-1172
    ISSN (online) 1750-1172
    ISSN 1750-1172
    DOI 10.1186/s13023-024-03060-w
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Salt and water loss in the distal colon.

    Berman, Jonathan M / Stockand, James D

    The Journal of physiology

    2016  Band 593, Heft 24, Seite(n) 5229

    Mesh-Begriff(e) Colon ; Humans ; Sodium Chloride ; Sodium Chloride, Dietary ; Water
    Chemische Substanzen Sodium Chloride, Dietary ; Water (059QF0KO0R) ; Sodium Chloride (451W47IQ8X)
    Sprache Englisch
    Erscheinungsdatum 2016-01-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP271666
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Liddle's syndrome mechanisms, diagnosis and management.

    Enslow, Benjamin T / Stockand, James D / Berman, Jonathan M

    Integrated blood pressure control

    2019  Band 12, Seite(n) 13–22

    Abstract: Liddle's syndrome is a genetic disorder characterized by hypertension with hypokalemic metabolic alkalosis, hyporeninemia and suppressed aldosterone secretion that often appears early in life. It results from inappropriately elevated sodium reabsorption ... ...

    Abstract Liddle's syndrome is a genetic disorder characterized by hypertension with hypokalemic metabolic alkalosis, hyporeninemia and suppressed aldosterone secretion that often appears early in life. It results from inappropriately elevated sodium reabsorption in the distal nephron. Liddle's syndrome is caused by mutations to subunits of the Epithelial Sodium Channel (ENaC). Among other mechanisms, such mutations typically prevent ubiquitination of these subunits, slowing the rate at which they are internalized from the membrane, resulting in an elevation of channel activity. A minority of Liddle's syndrome mutations, though, result in a complementary effect that also elevates activity by increasing the probability that ENaC channels within the membrane are open. Potassium-sparing diuretics such as amiloride and triamterene reduce ENaC activity, and in combination with a reduced sodium diet can restore normotension and electrolyte imbalance in Liddle's syndrome patients and animal models. Liddle's syndrome can be diagnosed clinically by phenotype and confirmed through genetic testing. This review examines the clinical features of Liddle's syndrome, the differential diagnosis of Liddle's syndrome and differentiation from other genetic diseases with similar phenotype, and what is currently known about the population-level prevalence of Liddle's syndrome. This review gives special focus to the molecular mechanisms of Liddle's syndrome.
    Sprache Englisch
    Erscheinungsdatum 2019-09-03
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2520711-8
    ISSN 1178-7104
    ISSN 1178-7104
    DOI 10.2147/IBPC.S188869
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Accuracy of US CDC COVID-19 Forecasting Models

    Chharia, Aviral / Jeevan, Govind / Jha, Rajat Aayush / Liu, Meng / Berman, Jonathan M / Glorioso, Christin A

    medRxiv

    Abstract: Accurate predictive modeling of pandemics is essential for optimally distributing resources and setting policy. Dozens of case predictions models have been proposed but their accuracy over time and by model type remains unclear. In this study, we analyze ...

    Abstract Accurate predictive modeling of pandemics is essential for optimally distributing resources and setting policy. Dozens of case predictions models have been proposed but their accuracy over time and by model type remains unclear. In this study, we analyze all US CDC COVID-19 forecasting models, by first categorizing them and then calculating their mean absolute percent error, both wave-wise and on the complete timeline. We compare their estimates to government-reported case numbers, one another, as well as two baseline models wherein case counts remain static or follow a simple linear trend. The comparison reveals that more than one-third of models fail to outperform a simple static case baseline and two-thirds fail to outperform a simple linear trend forecast. A wave-by-wave comparison of models revealed that no overall modeling approach was superior to others, including ensemble models, and error in modeling has increased over time during the pandemic. This study raises concerns about hosting these models on official public platforms of health organizations including the US-CDC which risks giving them an official imprimatur and further raising concerns if utilized to formulate policy. By offering a universal evaluation method for pandemic forecasting models, we expect this work to serve as the starting point towards the development of more sophisticated models.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2022-04-21
    Verlag Cold Spring Harbor Laboratory Press
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2022.04.20.22274097
    Datenquelle COVID19

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  10. Artikel ; Online: COVID-19 activity risk calculator as a gamified public health intervention tool.

    Natraj, Shreyasvi / Bhide, Malhar / Yap, Nathan / Liu, Meng / Seth, Agrima / Berman, Jonathan / Glorioso, Christin

    Scientific reports

    2023  Band 13, Heft 1, Seite(n) 13056

    Abstract: The Coronavirus disease 2019 (COVID-19) pandemic, caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted over 200 countries leading to hospitalizations and deaths of millions of people. Public health interventions, ...

    Abstract The Coronavirus disease 2019 (COVID-19) pandemic, caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted over 200 countries leading to hospitalizations and deaths of millions of people. Public health interventions, such as risk estimators, can reduce the spread of pandemics and epidemics through influencing behavior, which impacts risk of exposure and infection. Current publicly available COVID-19 risk estimation tools have had variable effectiveness during the pandemic due to their dependency on rapidly evolving factors such as community transmission levels and variants. There has also been confusion surrounding certain personal protective strategies such as risk reduction by mask-wearing and vaccination. In order to create a simple easy-to-use tool for estimating different individual risks associated with carrying out daily-life activity, we developed COVID-19 Activity Risk Calculator (CovARC). CovARC is a gamified public health intervention as users can "play with" how different risks associated with COVID-19 can change depending on several different factors when carrying out routine daily activities. Empowering the public to make informed, data-driven decisions about safely engaging in activities may help to reduce COVID-19 levels in the community. In this study, we demonstrate a streamlined, scalable and accurate COVID-19 risk calculation system. Our study also demonstrates the quantitative impact of vaccination and mask-wearing during periods of high case counts. Validation of this impact could inform and support policy decisions regarding case thresholds for mask mandates, and other public health interventions.
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; SARS-CoV-2 ; Public Health ; Pandemics/prevention & control
    Sprache Englisch
    Erscheinungsdatum 2023-08-11
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-40338-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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