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  1. Book ; Online ; E-Book: Symbiosis

    Kloc, Malgorzata

    cellular, molecular, medical and evolutionary aspects

    (Results and Problems in Cell Differentiation, ; 69)

    2020  

    Abstract: This volume presents a comprehensive overview of the latest developments in symbiosis research. It covers molecular, organellar, cellular, immunologic, genetic and evolutionary aspects of symbiotic interactions in humans and other model systems. The book ...

    Author's details edited by Malgorzata Kloc
    Series title Results and Problems in Cell Differentiation, ; 69
    Results and problems in cell differentiation
    Results and problems in cell differentiation
    Collection Results and problems in cell differentiation
    Results and problems in cell differentiation
    Abstract This volume presents a comprehensive overview of the latest developments in symbiosis research. It covers molecular, organellar, cellular, immunologic, genetic and evolutionary aspects of symbiotic interactions in humans and other model systems. The book also highlights new approaches to interdisciplinary research and therapeutic applications. Symbiosis refers to any mutually beneficial interaction between different organisms. The symbiotic origin of cellular organelles and the exchange of genetic material between hosts and their bacterial and viral symbionts have helped shaped the current diversity of life. Recently, symbiosis has gained a new level of recognition, due to the realization that all organisms function as a holobiome and that any kind of interference with the hosts influences their symbionts and vice versa, and can have profound consequences for the survival of both. For example, in humans, the microbiome, i.e., the entirety of all the microorganisms living in association with the intestines, oral cavity, urogenital system and skin, is partially inherited during pregnancy and influences the maturation and functioning of the human immune system, protects against pathogens and regulates metabolism. Symbionts also regulate cancer development, wound healing, tissue regeneration and stem cell function. The medical applications of this new realization are vast and largely uncharted. The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.
    Keywords Microbiology
    Subject code 780
    Language English
    Size 1 online resource (XI, 616 p. 83 illus., 71 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-51849-3 ; 3-030-51848-5 ; 978-3-030-51849-3 ; 978-3-030-51848-6
    DOI 10.1007/978-3-030-51849-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Book ; Online ; E-Book: Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine

    Kloc, Malgorzata / Kubiak, Jacek Z.

    (Results and Problems in Cell Differentiation, ; 70)

    2022  

    Abstract: This volume reviews the latest research on the functional implications of nuclear, chromosomal and genomic organization and architecture on cell and organismal biology, and development and progression of diseases. The architecture of the cell nucleus and ...

    Author's details edited by Malgorzata Kloc, Jacek Z. Kubiak
    Series title Results and Problems in Cell Differentiation, ; 70
    Results and problems in cell differentiation
    Collection Results and problems in cell differentiation
    Abstract This volume reviews the latest research on the functional implications of nuclear, chromosomal and genomic organization and architecture on cell and organismal biology, and development and progression of diseases. The architecture of the cell nucleus and non-random arrangement of chromosomes, genes, and the non-membranous nuclear bodies in the three-dimensional (3D) space alters in response to the environmental, mechanical, chemical, and temporal cues. The changes in the nuclear, chromosomal, or genomic compaction and configuration modify the gene expression program and induce or inhibit epigenetic modifications. The intrinsically programmed rearrangements of the nuclear architecture are necessary for cell differentiation, the establishment of cell fate during development and maturation of tissues and organs including the immune, muscle, and nervous systems. The non-programmed changes in the nuclear architecture can lead to fragmentation of the nucleus and instability of the genome and thus cause cancer. Microbial and viral infections can lead to a clustering of centromeres, telomeres and ribosomal DNA and alter the properties of the nuclear membrane, allowing large immobile macromolecules to enter the nucleus. Recent advances in next-generation sequencing technologies combined with nucleus/chromosome conformation capture, super-resolution imaging, chromosomal contact maps methods, integrative modeling, and genetic approaches, are uncovering novel features and importance of nuclear, chromosomal and genomic architecture. This book is an interesting read for cell biologists, researchers studying the structure and function of chromosomes, and anyone else who wants to get an overview of the field of nuclear, chromosomal and genomic architecture.
    Keywords Cell nuclei ; Chromosomes ; Biology/Technique ; Genomics ; Biomaterials ; Nucleic acids ; Gene expression ; Nuclear Organization ; Genomic Analysis ; Nucleic Acid ; Gene Expression Analysis
    Subject code 571.835
    Language English
    Size 1 online resource (657 pages)
    Edition 1st ed. 2022.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-031-06573-5 ; 9783031065729 ; 978-3-031-06573-6 ; 3031065727
    DOI 10.1007/978-3-031-06573-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  3. Book: Macrophages

    Kloc, Malgorzata

    origin, functions and biointervention

    (Results and problems in cell differentiation ; Volume 62)

    2017  

    Author's details Malgorzata Kloc, editor
    Series title Results and problems in cell differentiation ; Volume 62
    Collection
    Language English
    Size X, 376 Seiten, Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019332592
    ISBN 978-3-319-54089-4 ; 9783319540900 ; 3-319-54089-0 ; 3319540904
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 1002 available for loan (reading room) Lesesaal EG

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  4. Book: Oocytes

    Kloc, Malgorzata

    maternal information and functions

    (Results and problems in cell differentiation ; 63)

    2017  

    Author's details Malgorzata Kloc
    Series title Results and problems in cell differentiation ; 63
    Collection
    Keywords Oocytes ; Oosome ; Maternal information ; Maternal functions ; Oocyte activation ; Translational regulation ; CRISPR technology
    Subject code 570
    Language English
    Size xi, 510 Seiten in 1 Teil, Illustrationen, Diagramme, 23.5 cm x 15.5 cm
    Publisher Springer International Publishing
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019426008
    ISBN 978-3-319-60854-9 ; 3-319-60854-1 ; 9783319608556 ; 331960855X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 1435 available for loan (reading room) Lesesaal EG

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  5. Article ; Online: Seahorse Male Pregnancy as a Model System to Study Pregnancy, Immune Adaptations, and Environmental Effects.

    Kloc, Malgorzata

    International journal of molecular sciences

    2023  Volume 24, Issue 11

    Abstract: Seahorses, together with sea dragons and pipefishes, belong to ... ...

    Abstract Seahorses, together with sea dragons and pipefishes, belong to the
    MeSH term(s) Animals ; Male ; Acclimatization ; Climate ; Embryonic Development ; Fishes ; Mammals ; Smegmamorpha ; Pregnancy
    Language English
    Publishing date 2023-06-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24119712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Seahorse Male Pregnancy as a Model System to Study Pregnancy, Immune Adaptations, and Environmental Effects

    Malgorzata Kloc

    International Journal of Molecular Sciences, Vol 24, Iss 9712, p

    2023  Volume 9712

    Abstract: Seahorses, together with sea dragons and pipefishes, belong to the Syngnathidae family of teleost fishes. Seahorses and other Syngnathidae species have a very peculiar feature: male pregnancy. Among different species, there is a gradation of paternal ... ...

    Abstract Seahorses, together with sea dragons and pipefishes, belong to the Syngnathidae family of teleost fishes. Seahorses and other Syngnathidae species have a very peculiar feature: male pregnancy. Among different species, there is a gradation of paternal involvement in carrying for the offspring, from a simple attachment of the eggs to the skin surface, through various degrees of egg coverage by skin flaps, to the internal pregnancy within a brood pouch, which resembles mammalian uterus with the placenta. Because of the gradation of parental involvement and similarities to mammalian pregnancy, seahorses are a great model to study the evolution of pregnancy and the immunologic, metabolic, cellular, and molecular processes of pregnancy and embryo development. Seahorses are also very useful for studying the effects of pollutants and environmental changes on pregnancy, embryo development, and offspring fitness. We describe here the characteristics of seahorse male pregnancy, its regulatory mechanisms, the development of immune tolerance of the parent toward the allogeneic embryos, and the effects of environmental pollutants on pregnancy and embryo development.
    Keywords seahorse ; male pregnancy ; brood pouch ; placenta ; MHC ; pollution ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 570
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article ; Online: Remembering Professor Bohdan Matuszewski.

    Kloc, Malgorzata

    Developmental biology

    2022  Volume 487, Page(s) 21–23

    Abstract: Every one of us meets during our lifetime thousands of people. Most of them linger for a while in our memory and disappear. Others become long-term memory. But if you are lucky, you meet at least one exceptional person who becomes engraved in your heart ... ...

    Abstract Every one of us meets during our lifetime thousands of people. Most of them linger for a while in our memory and disappear. Others become long-term memory. But if you are lucky, you meet at least one exceptional person who becomes engraved in your heart and memory forever. I had such luck. In my life, this extraordinary person was Professor Bohdan Matuszewski. He was my Ph.D. advisor, and when I worked under his supervision at the Department of Cytology at Warsaw University, his personality and teachings made me a scientist. The accompanying article is just a tiny sliver of my memory about Professor Matuszewski, His friendship, and how He shaped my life.
    Language English
    Publishing date 2022-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1114-9
    ISSN 1095-564X ; 0012-1606
    ISSN (online) 1095-564X
    ISSN 0012-1606
    DOI 10.1016/j.ydbio.2022.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 508: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Why Do We Study Aquatic Organisms?

    Kloc, Malgorzata / Kubiak, Jacek Z

    International journal of molecular sciences

    2023  Volume 24, Issue 21

    Abstract: Aquatic organisms comprising various plant and animal taxa represent a wide range of adaptations to a specific environment, but they also share many features with nonaquatic organisms of a given taxonomic group.[ ... ]. ...

    Abstract Aquatic organisms comprising various plant and animal taxa represent a wide range of adaptations to a specific environment, but they also share many features with nonaquatic organisms of a given taxonomic group.[...].
    MeSH term(s) Animals ; Aquatic Organisms
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242115807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Remembering Professor Bohdan Matuszewski

    Kloc, Malgorzata

    Developmental biology. 2022 July, v. 487

    2022  

    Abstract: Every one of us meets during our lifetime thousands of people. Most of them linger for a while in our memory and disappear. Others become long-term memory. But if you are lucky, you meet at least one exceptional person who becomes engraved in your heart ... ...

    Abstract Every one of us meets during our lifetime thousands of people. Most of them linger for a while in our memory and disappear. Others become long-term memory. But if you are lucky, you meet at least one exceptional person who becomes engraved in your heart and memory forever. I had such luck. In my life, this extraordinary person was Professor Bohdan Matuszewski. He was my Ph.D. advisor, and when I worked under his supervision at the Department of Cytology at Warsaw University, his personality and teachings made me a scientist. The accompanying article is just a tiny sliver of my memory about Professor Matuszewski, His friendship, and how He shaped my life.
    Keywords cell biology ; heart ; interpersonal relationships ; personality ; scientists
    Language English
    Dates of publication 2022-07
    Size p. 21-23.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 1114-9
    ISSN 1095-564X ; 0012-1606
    ISSN (online) 1095-564X
    ISSN 0012-1606
    DOI 10.1016/j.ydbio.2022.04.002
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 76/715: Show issues

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  10. Article ; Online: The Role of Human and Animal Monocytes and Macrophages in Homeostasis and Disease.

    Kloc, Malgorzata / Kubiak, Jacek Z

    International journal of molecular sciences

    2023  Volume 24, Issue 22

    Abstract: Monocytes and macrophages are the innate immune cells that are the first-line responders to invading pathogens or foreign objects[ ... ]. ...

    Abstract Monocytes and macrophages are the innate immune cells that are the first-line responders to invading pathogens or foreign objects[...].
    MeSH term(s) Animals ; Humans ; Monocytes ; Macrophages ; Homeostasis ; Immunity, Innate
    Language English
    Publishing date 2023-11-16
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242216397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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