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  1. Book ; Online: Diets, Foods and Food Components Effect on Dyslipidemia

    Fogacci, Federica / Cicero, Arrigo / Borghi, Claudio

    2021  

    Keywords Public health & preventive medicine ; beta-glucan ; fiber ; lipid profile ; cholesterol ; intestinal function ; green tea ; epigallocatechin gallate ; chitosan ; microspheres ; Eudragit ; metabolic diseases ; LCD score ; CHNS ; dyslipidemia ; dietary factor ; plant based ; animal based ; Chinese adults ; nutraceuticals ; PCSK9 ; SREBP ; HNF1α ; berberine ; metabolic syndrome ; plant extracts ; natural antioxidant ; polyphenols ; bergamot ; blackcurrant ; liver steatosis ; ovariectomized ; phytoestrogen ; vitamin B12 ; healthy ; Saudi Arabia ; serum cholesterol ; serum triglycerides ; serum low density lipoprotein ; serum high density lipoprotein ; dietary intake ; lifestyle ; black raspberry ; excessive choline ; TMAO ; hypercholesterolemia ; hepatic inflammation ; review ; CVD ; cardiovascular health ; dietary fats ; dietary fiber ; phytosterols ; plant-based diet ; dietary pattern ; sustainability ; propolis ; formononetin ; gastric ulcer ; rats ; Chrysanthemum morifolium Ramat leaves ; obesity ; lipidomics ; liquid chromatography tandem mass spectrometry ; phospholipid ; sphingolipid ; monacolins ; LDL-cholesterol ; red yeast rice ; clinical trial ; endothelial function ; alpha-linolenic acid ; flaxseed ; lipids ; omega-3 ; walnuts ; type 2 diabetes mellitus ; glibenclamide ; omega-3 fatty acids ; high fat diet ; transcription factors ; streptozotocin ; Armolipid Plus® ; nutraceutical ; supplementation ; blood pressure ; fasting plasma glucose ; n/a
    Size 1 electronic resource (300 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021290977
    ISBN 9783036512396 ; 303651239X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Why this special section?

    Borghi, Claudio

    Nutrition, metabolism, and cardiovascular diseases : NMCD

    2023  Volume 33, Issue 2, Page(s) 307

    Language English
    Publishing date 2023-01-02
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1067704-5
    ISSN 1590-3729 ; 0939-4753
    ISSN (online) 1590-3729
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2023.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Coffee and blood pressure: exciting news!

    Borghi, Claudio

    Blood pressure

    2022  Volume 31, Issue 1, Page(s) 284–287

    Abstract: A growing number of epidemiological studies have reported the beneficial effects of habitual coffee consumption on incident cardiovascular disease (CVD), and mortality. However, the effects of coffee on arterial hypertension are still objects of active ... ...

    Abstract A growing number of epidemiological studies have reported the beneficial effects of habitual coffee consumption on incident cardiovascular disease (CVD), and mortality. However, the effects of coffee on arterial hypertension are still objects of active discussion mainly because of the debated effects of caffeine on blood pressure and cardiovascular system. In particular, the negative impact of caffeine would involve the whole cardiovascular system and could be responsible for an excess in the relative risk of new onset of hypertension and a worsening of blood pressure control. Recent evidence has been published excluding a significant effect of coffee consumption on hypertension development and blood pressure control in treated and untreated hypertensive supporting a protective role for the antioxidant components of coffee that may counteract the claimed negative effect of caffeine. The presence and amount of caffeine and cardio-protective chemical constituents of coffee is largely dependent on the type, production, and method of preparation and this can partially explain the divergent opinions on the effects of coffee intake on blood pressure and cardiovascular system. In addition, some genetic aspect of caffeine metabolism can contribute to the heterogeneity of published evidence while the most recent cardiovascular guidelines largely endorse coffee consumption in hypertension and CV disease. The purpose of this short review is to briefly summarise some of the recent information available in the literature on coffee and blood pressure.Key points  According to the considerable amount of observational evidence we can suggest that:  • While acute coffee administration in non-habitual users may induce a blood pressure rise, habitual coffee consumption in medium-high dosages (from 3 to 5 cups/day), has neutral or even beneficial impact on blood pressure values and the new onset of hypertension.   • The same intake significantly reduces the incidence of cardiovascular disease, as well as all-cause mortality.   • The consumption of coffee is compatible with a correct and balanced lifestyle and should therefore not be discouraged in subjects with hypertension and cardiovascular diseases.
    MeSH term(s) Humans ; Blood Pressure ; Coffee ; Caffeine/pharmacology ; Cardiovascular Diseases/prevention & control ; Cardiovascular Diseases/epidemiology ; Hypertension ; Risk Factors
    Chemical Substances Coffee ; Caffeine (3G6A5W338E)
    Language English
    Publishing date 2022-10-31
    Publishing country England
    Document type News
    ZDB-ID 1170048-8
    ISSN 1651-1999 ; 1651-2480 ; 0803-7051 ; 0803-8023
    ISSN (online) 1651-1999 ; 1651-2480
    ISSN 0803-7051 ; 0803-8023
    DOI 10.1080/08037051.2022.2136621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Xanthine oxidase inhibition and cardiovascular protection: Don't shoot in the dark.

    Desideri, Giovambattista / Borghi, Claudio

    European journal of internal medicine

    2023  Volume 113, Page(s) 10–12

    MeSH term(s) Humans ; Xanthine Oxidase ; Gout ; Hyperuricemia
    Chemical Substances Xanthine Oxidase (EC 1.17.3.2)
    Language English
    Publishing date 2023-04-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2023.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Clinical results and mechanism of action of icosapent ethyl.

    Borghi, Claudio / Bragagni, Alessio

    European heart journal supplements : journal of the European Society of Cardiology

    2023  Volume 25, Issue Suppl B, Page(s) B37–B40

    Abstract: Serum triglyceride concentration is considered as an additional component that often contributes to residual cardiovascular risk in patients already at high risk; these considerations have led to several clinical studies aimed at evaluating the efficacy ... ...

    Abstract Serum triglyceride concentration is considered as an additional component that often contributes to residual cardiovascular risk in patients already at high risk; these considerations have led to several clinical studies aimed at evaluating the efficacy of supplements based on omega-3 fatty acids in reducing serum triglyceride levels and consequently cardiovascular risk. Although partially inconclusive and contradictory, these clinical trials laid the foundations for the implementation of the REDUCE-IT and EVAPORATE studies, in which the use of a purified derivative of eicosapentaenoic acid, icosapent ethyl, resulted in a significant reduction both of the composite for cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke and of the reduction in the volumetric progression up to the induction of a real regression of the coronary atheromatous plaques detected by computerized coronary angiography tomography. Surprisingly, these brilliant results seem to be, at least in part, not related to the reduction of triglyceride concentration. The purpose of this article is to examine the latest evidence regarding icosapent ethyl therapy, describing the results of the main clinical trials performed to date and formulating hypotheses on the potential mechanisms of action of this fascinating molecule.
    Language English
    Publishing date 2023-04-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1463769-8
    ISSN 1554-2815 ; 1520-765X
    ISSN (online) 1554-2815
    ISSN 1520-765X
    DOI 10.1093/eurheartjsupp/suad088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Estimating the impact of single pill combination therapy for hypertension: projections of patient outcomes in Italy.

    Borghi, Claudio / Granados, Denis

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 10, Page(s) 714–720

    Abstract: Introduction: Hypertension affects almost a third of the Italian population and is a major risk factor for cardiovascular disease. Management of hypertension is often hindered by poor adherence to complex treatment regimens. This analysis aimed to ... ...

    Abstract Introduction: Hypertension affects almost a third of the Italian population and is a major risk factor for cardiovascular disease. Management of hypertension is often hindered by poor adherence to complex treatment regimens. This analysis aimed to estimate the 10-year clinical outcomes associated with single pill combination (SPC) therapies compared with other treatment pathways for the management of hypertension in Italy.
    Methods: A microsimulation modeling approach was used to project health outcomes over a 10-year period for people with hypertension. Input data for four treatment pathways [current treatment practices (CTP), single drug with dosage titration then sequential addition of other agents (start low and go slow, SLGS), free choice combination with multiple pills (FCC) and SPC] were sourced from the Global Burden of Disease 2017 data set. The model simulated clinical outcomes for 1 000 000 individuals in each treatment pathway, including mortality, chronic kidney disease (CKD), stroke, ischemic heart disease (IHD) and disability-adjusted life years (DALYs).
    Results: Through improved adherence, SPC was projected to improve clinical outcomes versus CTP, SLGS, and FCC. SPC was associated with reductions in mortality, incidence of clinical events, and DALYs versus CTP of 5.4%, 11.5%, and 5.7%, respectively. SLGS and FCC were associated with improvements in clinical outcomes versus CTP, but smaller improvements than those associated with SPC.
    Conclusions: Over 10 years, combination therapies (including SPC and FCC) were projected to reduce the burden of hypertension compared with conventional management approaches in Italy. Due to higher adherence, SPC was associated with the greatest overall benefits versus other regimens.
    MeSH term(s) Humans ; Antihypertensive Agents/adverse effects ; Drug Combinations ; Hypertension/diagnosis ; Hypertension/drug therapy ; Hypertension/epidemiology ; Cardiovascular Diseases/epidemiology ; Risk Factors
    Chemical Substances Antihypertensive Agents ; Drug Combinations
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Gout and CV disease: It is time to move on.

    Borghi, Claudio

    International journal of cardiology

    2018  Volume 270, Page(s) 311

    MeSH term(s) Cardiovascular Diseases ; Gout ; Humans ; Hyperuricemia
    Language English
    Publishing date 2018-09-13
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2018.07.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An Evolving Definition of a "Healthy Diet".

    Cicero, Arrigo F G / Fogacci, Federica / Borghi, Claudio

    Nutrients

    2023  Volume 15, Issue 9

    Abstract: Throughout life, most of us eat at least three meals a day for 365 days a year [ ... ]. ...

    Abstract Throughout life, most of us eat at least three meals a day for 365 days a year [...].
    MeSH term(s) Diet, Healthy ; Meals
    Language English
    Publishing date 2023-05-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15092212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Is the First Cut Always the Deepest?

    Borghi, Claudio / Di Micoli, Antonio / Fiorini, Giulia

    Hypertension (Dallas, Tex. : 1979)

    2023  Volume 80, Issue 6, Page(s) 1180–1182

    MeSH term(s) Humans ; Colorectal Neoplasms ; Multivariate Analysis
    Language English
    Publishing date 2023-05-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.20701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: L'impiego die ezetimibe nella pratica clinica

    Borghi, Claudio / Perrone Filardi, Pasquale

    dal laboratorio all'IMPROVE-IT

    (Giornale italiano di cardiologia ; volume 16, suppl. 1 al n. 7-8)

    2015  

    Author's details guest editors Claudia Borghi e Pasquale Perrone Filardi
    Series title Giornale italiano di cardiologia ; volume 16, suppl. 1 al n. 7-8
    Collection
    Language Italian
    Size 14S Seiten, Illustrationen
    Publisher Il Pensiero Scientifico Editore
    Publishing place Roma
    Publishing country Italy
    Document type Book
    HBZ-ID HT018860812
    Database Catalogue ZB MED Medicine, Health

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