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  1. Article ; Online: Luangrath and Wen Respond.

    Luangrath, Narintohn / Wen, Leana S

    American journal of public health

    2018  Volume 108, Issue 9, Page(s) e6–e7

    MeSH term(s) Cities ; Drugs, Chinese Herbal
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2018-08-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2018.304618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Aeschynanthus smaragdinus F.Wen & J.Q.Qin (Gesneriaceae), a new species from Yunnan Province, China

    Qin, Jia-Qi / Li, Rui-Feng / Pang, Yan-Ping / Wen, Fang

    PhytoKeys. 2023 Feb. 24, v. 220 p.65-73

    2023  

    Abstract: AbstractAeschynanthus smaragdinus F.Wen & J.Q.Qin, a new species of Gesneriaceae from the monsoon ...

    Abstract AbstractAeschynanthus smaragdinus F.Wen & J.Q.Qin, a new species of Gesneriaceae from the monsoon rain forest in Mangbang township, Tengchong City, Yunnan Province, China, is described and illustrated here. It morphologically resembles A. chiritoides C.B.Clarke in size, shape and hairs on the leaf blades. But it can easily be distinguished from the latter by the green corolla limb with brownish-red to maroon lower lobes. At the same time, the hairs of the pedicel and calyx lobes, the length of the staminode and the size of the seed grain can also help distinguish both. It is provisionally assessed as Data Deficient (DD), according to the IUCN Red List Categories and Criteria, because field surveys for this new taxon have not been completed.
    Keywords Gesneriaceae ; calyx ; corolla ; leaves ; monsoon season ; new species ; pedicel ; rain forests ; seed size ; China ; Aeschynanthuschiritoides ; Didymocarpoideae ; Flora of Yunnan ; taxonomy
    Language English
    Dates of publication 2023-0224
    Size p. 65-73.
    Publishing place Pensoft Publishers
    Document type Article ; Online
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.220.98040
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Qing-Wen-Jie-Re Mixture Ameliorates Poly (I:C)-Induced Viral Pneumonia Through Regulating the Inflammatory Response and Serum Metabolism.

    Li, Qin / Zhang, Tingrui / Wang, Yuming / Yang, Shangsong / Luo, Junyu / Fang, Fang / Liao, Jiabao / Wen, Weibo / Cui, Huantian / Shang, Hongcai

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 891851

    Abstract: Qing-Wen-Jie-Re mixture (QWJR) has been used in the treatment of the coronavirus disease 2019 ...

    Abstract Qing-Wen-Jie-Re mixture (QWJR) has been used in the treatment of the coronavirus disease 2019 (COVID-19) in China. However, the protective mechanisms of QWJR on viral pneumonia remain unclear. In the present study, we first investigated the therapeutic effects of QWJR on a rat viral pneumonia model established by using polyinosinic-polycytidylic acid (poly (I:C)). The results indicated that QWJR could relieve the destruction of alveolar-capillary barrier in viral pneumonia rats, as represented by the decreased wet/dry weight (W/D) ratio in lung, total cell count and total protein concentration in bronchoalveolar lavage fluid (BALF). Besides, QWJR could also down-regulate the expression of inflammatory factors such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1β and IL-6. More M1-type macrophage polarization was detected by calculating CD86
    Language English
    Publishing date 2022-06-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.891851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter by Wen et al Regarding Article, "Increased Wall Enhancement During Follow-Up as a Predictor of Subsequent Aneurysmal Growth".

    Wen, Dingke / Xiao, Yue / Yang, Mu

    Stroke

    2020  Volume 51, Issue 10, Page(s) e293–e294

    MeSH term(s) Aneurysm, Ruptured ; Follow-Up Studies ; Humans ; Intracranial Aneurysm
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.030943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 448: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Letter by Wen et al Regarding Article, "Validation of Wall Enhancement as a New Imaging Biomarker of Unruptured Cerebral Aneurysm".

    Wen, Dingke / Ma, Lu / Yang, Mu

    Stroke

    2019  Volume 50, Issue 10, Page(s) e305

    MeSH term(s) Aneurysm, Ruptured ; Biomarkers ; Cerebral Angiography ; Humans ; Intracranial Aneurysm
    Chemical Substances Biomarkers
    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.119.026830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 448: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Efficacy and safety of Chinese herbal medicine Wen Xin granules for the treatment of unstable angina pectoris with Yang deficiency and blood stasis syndrome: study protocol for a randomized controlled trial.

    Tian, Pan-Pan / Wu, Qing-Juan / Li, Jun / Chen, Heng-Wen / Wu, Ji / Deng, Ya-Wen / Xie, Zi-Cong / Zhao, Wei / Tan, Yu-Qing

    Trials

    2021  Volume 22, Issue 1, Page(s) 798

    Abstract: ... stasis syndrome is a common type of UAP. Wen Xin decoction, as a type of Chinese herbal medicine, has ... and blood stasis syndrome. This study aims to evaluate the efficacy and safety of Wen Xin granular ... group. Based on conventional medication, the intervention group will be treated with Wen Xin granular ...

    Abstract Introduction: Unstable angina pectoris (UAP) is the common type of coronary heart disease with the risk of developing into acute myocardial infarction (AMI). Currently, there are still numerous patients suffering from recurrent angina after revascularization or conventional medication due to the microvascular lesions, endothelial dysfunction, chronic inflammation, in-stent restenosis, and other factors. As an important part of China's medical and health care system, traditional Chinese medicine (TCM) has rich clinical experience in the treatment of UAP. According to the theory of TCM, Yang deficiency and blood stasis syndrome is a common type of UAP. Wen Xin decoction, as a type of Chinese herbal medicine, has been used in the clinic for years and shown great efficacy in the treatment of UAP with Yang deficiency and blood stasis syndrome. This study aims to evaluate the efficacy and safety of Wen Xin granular in patients with UAP.
    Methods and analysis: This is a double-blinded, randomized, placebo-controlled clinical trial. A total of 502 participants will be randomly allocated to the intervention group and the placebo group. Based on conventional medication, the intervention group will be treated with Wen Xin granular and the placebo group will be treated with Wen Xin granular placebo. The primary outcomes are major adverse cardiovascular events (MACE). Assessments will be performed 1 year after the treatment. The secondary outcomes include TCM symptom scale score, Seattle angina questionnaire, and thromboelastography. Assessments will be performed at baseline (before randomization) and 4 and 8 weeks after randomization.
    Discussion: This trial will provide high-quality data on the benefits and risks of Wen Xin granular in patients with UAP.
    Trial registration: ClinicalTrials.gov NCT04661709 . Registered on 30 November 2020.
    MeSH term(s) Angina, Unstable/diagnosis ; Angina, Unstable/drug therapy ; Double-Blind Method ; Drugs, Chinese Herbal/adverse effects ; Humans ; Medicine, Chinese Traditional ; Myocardial Infarction ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Yang Deficiency
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2021-11-13
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-021-05771-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Corrigendum to Heybeli C, Bentall A, Wen J, et al. A study from The Mayo Clinic evaluated long-term outcomes of kidney transplantation in patients with immunoglobulin light chain amyloidosis. Kidney Int. 2021;99:707-715.

    Heybeli, Cihan / Bentall, Andrew / Wen, Jiqiu / Alexander, Mariam Priya / Buadi, Francis K / Cosio, Fernando G / Dean, Patrick G / Dispenzieri, Angela / Dingli, David / El Ters, Mireille / Gertz, Morie A / Amer, Hatem / Kapoor, Prashant / Khamash, Hasan / Kourelis, Taxiarchis / Kumar, Shaji / Lorenz, Elizabeth C / Mai, Martin / Muchtar, Eli /
    Murray, David L / Prieto, Mikel / Schinstock, Carrie A / Stegall, Mark D / Warsame, Rahma / Leung, Nelson

    Kidney international

    2021  Volume 100, Issue 6, Page(s) 1348–1349

    Language English
    Publishing date 2021-10-09
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Letter by Wen et al Regarding Article, "Pathophysiology of Intracranial Aneurysms: COX-2 Expression, Iron Deposition in Aneurysm Wall, and Correlation With Magnetic Resonance Imaging".

    Wen, Dingke / Kieran, Nicholas W / Yang, Mu

    Stroke

    2020  Volume 51, Issue 12, Page(s) e367–e368

    MeSH term(s) Aneurysm, Ruptured ; Cyclooxygenase 2 ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Iron ; Magnetic Resonance Imaging
    Chemical Substances Iron (E1UOL152H7) ; Cyclooxygenase 2 (EC 1.14.99.1)
    Language English
    Publishing date 2020-11-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.031830
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 448: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Efficacy and safety of Chinese herbal medicine Wen Xin granules for the treatment of unstable angina pectoris with Yang deficiency and blood stasis syndrome

    Pan-pan Tian / Qing-juan Wu / Jun Li / Heng-wen Chen / Ji Wu / Ya-wen Deng / Zi-cong Xie / Wei Zhao / Yu-qing Tan

    Trials, Vol 22, Iss 1, Pp 1-

    study protocol for a randomized controlled trial

    2021  Volume 8

    Abstract: ... stasis syndrome is a common type of UAP. Wen Xin decoction, as a type of Chinese herbal medicine, has ... and blood stasis syndrome. This study aims to evaluate the efficacy and safety of Wen Xin granular ... group. Based on conventional medication, the intervention group will be treated with Wen Xin granular ...

    Abstract Abstract Introduction Unstable angina pectoris (UAP) is the common type of coronary heart disease with the risk of developing into acute myocardial infarction (AMI). Currently, there are still numerous patients suffering from recurrent angina after revascularization or conventional medication due to the microvascular lesions, endothelial dysfunction, chronic inflammation, in-stent restenosis, and other factors. As an important part of China’s medical and health care system, traditional Chinese medicine (TCM) has rich clinical experience in the treatment of UAP. According to the theory of TCM, Yang deficiency and blood stasis syndrome is a common type of UAP. Wen Xin decoction, as a type of Chinese herbal medicine, has been used in the clinic for years and shown great efficacy in the treatment of UAP with Yang deficiency and blood stasis syndrome. This study aims to evaluate the efficacy and safety of Wen Xin granular in patients with UAP. Methods and analysis This is a double-blinded, randomized, placebo-controlled clinical trial. A total of 502 participants will be randomly allocated to the intervention group and the placebo group. Based on conventional medication, the intervention group will be treated with Wen Xin granular and the placebo group will be treated with Wen Xin granular placebo. The primary outcomes are major adverse cardiovascular events (MACE). Assessments will be performed 1 year after the treatment. The secondary outcomes include TCM symptom scale score, Seattle angina questionnaire, and thromboelastography. Assessments will be performed at baseline (before randomization) and 4 and 8 weeks after randomization. Discussion This trial will provide high-quality data on the benefits and risks of Wen Xin granular in patients with UAP. Trial registration ClinicalTrials.gov NCT04661709 . Registered on 30 November 2020
    Keywords Coronary heart disease ; Unstable angina pectoris ; Wen Xin decoction ; Chinese herb medicine ; Randomized controlled trial ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article: Wen-Luo-Tong Decoction Attenuates Paclitaxel-Induced Peripheral Neuropathy by Regulating Linoleic Acid and Glycerophospholipid Metabolism Pathways.

    Wu, Fei-Ze / Xu, Wen-Juan / Deng, Bo / Liu, Si-da / Deng, Chao / Wu, Meng-Yu / Gao, Yu / Jia, Li-Qun

    Frontiers in pharmacology

    2018  Volume 9, Page(s) 956

    Abstract: ... diseases. Wen-Luo-Tong (WLT) is a TCM ointment for topical application. It has been applied for prevention ...

    Abstract Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting toxicity of many anti-neoplastic agents, especially paclitaxel, and oxaliplatin. Up to 62% of patients receiving paclitaxel regimens turn out to develop CIPN. Unfortunately, there are so few agents proved effective for prevention or management of CIPN. The reason for the current situation is that the mechanisms of CIPN are still not explicit. Traditional Chinese Medicine (TCM) has unique advantages for dealing with complex diseases. Wen-Luo-Tong (WLT) is a TCM ointment for topical application. It has been applied for prevention and management of CIPN clinically for more than 10 years. Previous animal experiments and clinical studies had manifested the availability of WLT. However, due to the unclear mechanisms of WLT, further transformation has been restricted. To investigate the therapeutic mechanisms of WLT, a metabolomic method on the basis of UPLC- MS was developed in this study. Multivariate analysis techniques, such as principal component analysis (PCA) and partial least squares discriminate analysis (PLS-DA), were applied to observe the disturbance in the metabolic state of the paclitaxel-induced peripheral neuropathy (PIPN) rat model, as well as the recovering tendency of WLT treatment. A total of 19 significant variations associated with PIPN were identified as biomarkers. Results of pathway analysis indicated that the metabolic disturbance of pathways of linoleic acid (LA) metabolism and glycerophospholipid metabolism. WLT attenuated mechanical allodynia and rebalanced the metabolic disturbances of PIPN by primarily regulating LA and glycerophospholipid metabolism pathway. Further molecular docking analysis showed some ingredients of WLT, such as hydroxysafflor yellow A (HSYA), icariin, epimedin B and 4-dihydroxybenzoic acid (DHBA), had high affinity to plenty of proteins within these two pathways.
    Language English
    Publishing date 2018-08-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2018.00956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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