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  1. Article: Elbow instability.

    Hickey, Derrick G / Loebennerg, Mark I

    Bulletin of the NYU hospital for joint diseases

    2006  Volume 64, Issue 3-4, Page(s) 166–171

    MeSH term(s) Biomechanical Phenomena ; Elbow Joint/injuries ; Elbow Joint/physiopathology ; Elbow Joint/surgery ; Electromyography ; Humans ; Joint Dislocations/surgery ; Joint Instability/diagnosis ; Joint Instability/physiopathology ; Joint Instability/surgery ; Ligaments, Articular/physiopathology ; Rotation
    Language English
    Publishing date 2006
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 390411-8
    ISSN 2328-5273 ; 1936-9727 ; 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
    ISSN (online) 2328-5273 ; 1936-9727
    ISSN 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Clinical applications of growth factors for articular cartilage repair.

    Hickey, Derrick G / Frenkel, Sally R / Di Cesare, Paul E

    American journal of orthopedics (Belle Mead, N.J.)

    2003  Volume 32, Issue 2, Page(s) 70–76

    Abstract: Articular cartilage injuries and degeneration present a challenge for orthopedic surgeons. Chondrocytes have limited regenerative and reparative abilities. Healing of a defect results in a fibrocartilaginous repair tissue that lacks the structural and ... ...

    Abstract Articular cartilage injuries and degeneration present a challenge for orthopedic surgeons. Chondrocytes have limited regenerative and reparative abilities. Healing of a defect results in a fibrocartilaginous repair tissue that lacks the structural and biomechanical properties of hyaline cartilage and that degrades over time. Polypeptide growth factors have an important role in regulating the behavior of all cells, including articular chondrocytes. Our understanding of growth factor effects on and interactions with chondrocytes is progressing rapidly. The most prominent growth factors identified for articular cartilage include insulin-like growth factor, fibroblast growth factor, the transforming growth factor-beta superfamily, hepatocyte growth factor, platelet-derived growth factor, Indian hedgehog and parathyroid hormone-related peptide, bone morphogenetic proteins, and the interleukin-1 receptor antagonist. Orthopedic surgeons need to be familiar with the properties of these growth factors, as they hold great therapeutic promise. In-progress clinical studies are examining how growth factors may have applications in treatments of bone.
    MeSH term(s) Cartilage, Articular/injuries ; Cartilage, Articular/pathology ; Cartilage, Articular/physiopathology ; Cartilage, Articular/surgery ; Chondrocytes/physiology ; Growth Substances/physiology ; Humans ; Orthopedic Procedures ; Wound Healing/physiology
    Chemical Substances Growth Substances
    Language English
    Publishing date 2003-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1235120-9
    ISSN 1078-4519
    ISSN 1078-4519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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