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  1. Article: Surgical management of the aortic arch in patients with inherited aortopathy.

    Lucchese, Gianluca / Bilkhu, Rajdeep

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 974190

    Abstract: Surgical management of the aortic root and ascending aorta has seen an evolution over the past 50 years. Despite the widely available guidelines for management of the aortic root and ascending aorta, including in those with connective tissue disease and ... ...

    Abstract Surgical management of the aortic root and ascending aorta has seen an evolution over the past 50 years. Despite the widely available guidelines for management of the aortic root and ascending aorta, including in those with connective tissue disease and inherited aortopathies, there are generally no clear guideline indications for when to intervene on the aortic arch in these patients. This perhaps may be related to the fact that whilst the majority of acquired aortopathies, and also in non-syndromic aortopathies such as in bicuspid aortic valve, size criteria are utilized to decide on when to intervene, the use of size criteria may not be appropriate in those with syndromic inherited aortopathies. The aim of the present mini review is to provide a general overview and guidance for the surgical management of patients with inherited aortopathies.
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.974190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Should We Be Worried About Patient-Prosthesis Mismatch?

    Bilkhu, Rajdeep / Jahangiri, Marjan

    The Annals of thoracic surgery

    2020  Volume 111, Issue 4, Page(s) 1290–1291

    MeSH term(s) Bioprosthesis ; Heart Valve Prosthesis ; Humans ; Registries
    Language English
    Publishing date 2020-09-19
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.06.131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 252: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Surgery for recurrent thymoma during the COVID-19 pandemic: a narrative review.

    Bilkhu, Rajdeep / Billè, Andrea

    Mediastinum (Hong Kong, China)

    2021  Volume 5, Page(s) 17

    Abstract: Patients who have undergone surgical resection of thymoma may present later with recurrence of disease. This is most commonly in the pleural cavity. Surgery for recurrent thymoma has been shown to have a survival advantage. During the COVID-19 pandemic, ... ...

    Abstract Patients who have undergone surgical resection of thymoma may present later with recurrence of disease. This is most commonly in the pleural cavity. Surgery for recurrent thymoma has been shown to have a survival advantage. During the COVID-19 pandemic, there has been a reduction in capacity for routine healthcare provision. We present the outcomes of patients undergoing surgery for recurrent thymoma during the COVID-19 pandemic and our protocols to allow surgery to be performed during this time. Retrospective review of patients undergoing surgery for recurrent thymoma between March 2020 and the March 2021 at a single centre was performed. Preoperative demographic data, postoperative outcomes and the incidence of complications or postoperative COVID-19 infection were assessed. Over a 4-year period, and under the care of a single surgeon, 7 operations were performed for recurrent thymoma. Of these, three patients were operated during the COVID-19 pandemic. All patients had a history of myasthenia gravis (MG) and all patients presented with disease recurrence in the pleural cavity. No patients had post-operative complications and no patients tested positive for COVID-19 in the pre or postoperative period. Complete macroscopic resection was achieved in all patients. Surgery for recurrent thymoma can be performed safely and complete macroscopic resection can be achieved. It is possible to offer surgery with low risk of perioperative COVID infection and related morbidity and mortality. Given the benefits seen in survival and disease-free survival, we believe surgery for recurrent thymoma should continue to be advocated even during the current viral pandemic.
    Language English
    Publishing date 2021-06-25
    Publishing country China
    Document type Journal Article ; Review
    ISSN 2522-6711
    ISSN (online) 2522-6711
    DOI 10.21037/med-21-10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Complete Surgical Resection of a Giant Invasive Thymoma with Right Pneumonectomy and Graft Reconstruction of the Superior Vena Cava and Left Brachiocephalic Vein: A Case Report.

    Lampridis, Savvas / Bilkhu, Rajdeep / Lucchese, Gianluca / Billè, Andrea

    Case reports in surgery

    2022  Volume 2022, Page(s) 9604926

    Abstract: Background: Complete surgical resection represents one of the most important prognostic factors for thymomas. However, surgery is usually not considered when there is invasion of the pulmonary hilum and mediastinal veins because of technical ... ...

    Abstract Background: Complete surgical resection represents one of the most important prognostic factors for thymomas. However, surgery is usually not considered when there is invasion of the pulmonary hilum and mediastinal veins because of technical considerations or potential perioperative morbidity and mortality.
    Conclusions: Complete surgical resection of invasive thymomas with concomitant pneumonectomy and venous graft reconstruction is a feasible and safe procedure. Careful patient selection and adequate postoperative anticoagulation are crucial for successful clinical outcomes.
    Language English
    Publishing date 2022-11-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2022/9604926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Should the Ross Procedure Be Considered in Infective Aortic Valve Endocarditis?

    Bilkhu, Rajdeep / Jahangiri, Marjan

    The Annals of thoracic surgery

    2020  Volume 110, Issue 3, Page(s) 861–862

    MeSH term(s) Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Endocarditis/surgery ; Heart Defects, Congenital ; Heart Valve Diseases/diagnostic imaging ; Heart Valve Diseases/surgery ; Humans ; Young Adult
    Language English
    Publishing date 2020-03-19
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 252: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Elective lung cancer surgery in the COVID-19 era: how do we do it?

    Bilkhu, Rajdeep / Billè, Andrea

    Tumori

    2020  , Page(s) 300891620931568

    Abstract: The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID- ... ...

    Abstract The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID-19 undergoing treatment is mandatory. We reviewed the experience of the National Institute of Cancer in Milan and compared it with our experience.
    Keywords covid19
    Language English
    Publishing date 2020-05-28
    Publishing country United States
    Document type Editorial
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.1177/0300891620931568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.43: Show issues Location:
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    Zs.MO 287: Show issues

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  7. Article ; Online: Contraceptive implant migration to the lung.

    Wali, Anuj / Bilkhu, Rajdeep / Rizzo, Victoria / Bille, Andrea

    BJR case reports

    2021  Volume 7, Issue 4, Page(s) 20200216

    Abstract: A 27-year-old female presented with a 'missing' contraceptive implant. Chest imaging demonstrated a 4-cm linear opacity in a subsegmental branch of the pulmonary artery to the left lower lobe consistent with a migrated contraceptive implant. A mini- ... ...

    Abstract A 27-year-old female presented with a 'missing' contraceptive implant. Chest imaging demonstrated a 4-cm linear opacity in a subsegmental branch of the pulmonary artery to the left lower lobe consistent with a migrated contraceptive implant. A mini-thoracotomy and arteriotomy was performed. The artery was opened distally to its third division. However, it was not possible to retrieve the implant, and the decision was made to proceed to segmentectomy. After resection, it was noted that the foreign body had significantly endothelialised within the wall of the artery and required sharp dissection for removal. This is the first case report to demonstrate the complete endothelialisation and subsequent difficulty in removal of an embolised contraceptive implant. We hope this report adds to the growing body of literature to guide management of this extremely rare but serious complication.
    Language English
    Publishing date 2021-05-12
    Publishing country England
    Document type Case Reports
    ISSN 2055-7159
    ISSN (online) 2055-7159
    DOI 10.1259/bjrcr.20200216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Improving outcomes of surgery in advanced infiltrative thymic tumours: the benefits of multidisciplinary approach.

    Billè, Andrea / Bilkhu, Rajdeep / Benedetti, Giulia / Lucchese, Gianluca

    Tumori

    2021  Volume 108, Issue 5, Page(s) 477–485

    Abstract: Background: For stage III or IVa thymic tumours, a multimodality approach is recommended. The role of surgery is to achieve complete resection.: Aim: To present the outcomes of patients undergoing surgery for stage III or IVa thymoma.: Methods: ... ...

    Abstract Background: For stage III or IVa thymic tumours, a multimodality approach is recommended. The role of surgery is to achieve complete resection.
    Aim: To present the outcomes of patients undergoing surgery for stage III or IVa thymoma.
    Methods: Retrospective review of patients undergoing open surgery for stage III or IVa thymoma between 2016 and 2020 at a single centre was performed. Preoperative imaging, treatment plan, surgical approach, and postoperative outcomes were analyzed.
    Results: Forty-seven patients underwent surgery for thymoma. Patients with clinical stage I/II thymoma or minimally invasive thymectomy were excluded. Thirteen patients with clinical stage III or IVa were included. Median sternotomy approach was used in four patients, of which one was redo sternotomy; a hemi-clamshell in four; and a combination of approaches in the remaining five patients. There was no postoperative mortality. Four patients had postoperative complications. Complete resection was achieved in all but two patients. At a median follow-up of 17.9 months, all patients were alive with no evidence of recurrence except one who died 4 months after surgery from coronavirus disease 2019 (COVID-19) pneumonia.
    Conclusions: Surgery for stage III and IVa thymoma is safe and can be achieved with complete macroscopic resection. To obtain adequate exposure of all structures involved in the tumour, combined surgical approaches can be used with no increased morbidity. The majority of patients, even after extrapleural pneumonectomy, did not receive adjuvant radiotherapy and had no evidence of local relapse.
    MeSH term(s) COVID-19 ; Humans ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Retrospective Studies ; Thymoma/pathology ; Thymus Neoplasms
    Language English
    Publishing date 2021-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.1177/03008916211023154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.43: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 287: Show issues

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  9. Article: Elective lung cancer surgery in the COVID-19 era: how do we do it?

    Bilkhu, Rajdeep / Billè, Andrea

    Tumori

    Abstract: The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID- ... ...

    Abstract The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID-19 undergoing treatment is mandatory. We reviewed the experience of the National Institute of Cancer in Milan and compared it with our experience.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #401599
    Database COVID19

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  10. Article ; Online: Elective lung cancer surgery in the COVID-19 era

    Bilkhu, Rajdeep / Billè, Andrea

    Tumori Journal

    how do we do it?

    2020  Volume 106, Issue 3, Page(s) 190–192

    Abstract: The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID- ... ...

    Abstract The coronavirus 2019 (COVID-19) pandemic has caused significant mortality around the world and the focus has been on reducing the number of infections. In order not to compromise treatment of oncology patients, reducing the number of patients with COVID-19 undergoing treatment is mandatory. We reviewed the experience of the National Institute of Cancer in Milan and compared it with our experience.
    Keywords Cancer Research ; Oncology ; General Medicine ; covid19
    Language English
    Publisher SAGE Publications
    Publishing country us
    Document type Article ; Online
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.1177/0300891620931568
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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