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  1. Article: At last...?: Michelle Obama, Beyoncé, race & history.

    Griffin, Farah Jasmine

    Daedalus

    2011  Volume 140, Issue 1, Page(s) 131–141

    Abstract: ... South. Griffin considers how Michelle Obama's and Beyoncé's use of their respective family histories and ... Michelle Obama and entertainment mogul Beyoncé Knowles. Both women signify change in race relations ... League-educated descendent of slaves, Michelle Obama is not just unfamiliar to the mainstream media and ...

    Abstract In this essay, Griffin brings to the fore two extraordinary black women of our age: First Lady Michelle Obama and entertainment mogul Beyoncé Knowles. Both women signify change in race relations in America, yet both reveal that the history of racial inequality in this country is far from over. As an Ivy League-educated descendent of slaves, Michelle Obama is not just unfamiliar to the mainstream media and the Washington political scene; during the 2008 presidential campaign, she was vilified as angry and unpatriotic. Beyoncé, who controls the direction of her career in a way that pioneering black women entertainers could not, has nonetheless styled herself in ways that recall the distinct racial history of the Creole South. Griffin considers how Michelle Obama's and Beyoncé's use of their respective family histories and ancestry has bolstered or diminished their popular appeal.
    MeSH term(s) African Americans/education ; African Americans/ethnology ; African Americans/history ; African Americans/legislation & jurisprudence ; African Americans/psychology ; Civil Rights/economics ; Civil Rights/education ; Civil Rights/history ; Civil Rights/legislation & jurisprudence ; Civil Rights/psychology ; Ethnic Groups/education ; Ethnic Groups/ethnology ; Ethnic Groups/history ; Ethnic Groups/legislation & jurisprudence ; Ethnic Groups/psychology ; Genealogy and Heraldry ; History, 20th Century ; History, 21st Century ; Humans ; Population Groups/education ; Population Groups/ethnology ; Population Groups/history ; Population Groups/legislation & jurisprudence ; Population Groups/psychology ; Race Relations/history ; Race Relations/legislation & jurisprudence ; Race Relations/psychology ; Social Behavior/history ; Social Conditions/economics ; Social Conditions/history ; Social Conditions/legislation & jurisprudence ; Social Mobility/economics ; Social Mobility/history ; Socioeconomic Factors/history ; United States/ethnology ; Women/education ; Women/history ; Women/psychology
    Language English
    Publishing date 2011-01-31
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 1648-2
    ISSN 1548-6192 ; 0011-5266
    ISSN (online) 1548-6192
    ISSN 0011-5266
    DOI 10.1162/daed_a_00065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Urgent Need to Define HbA1C Cutoffs in Hand Surgery.

    Griffin, Michelle F / Curtin, Catherine

    Hand (New York, N.Y.)

    2024  , Page(s) 15589447241233358

    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Letter
    ZDB-ID 2277325-3
    ISSN 1558-9455 ; 1558-9447
    ISSN (online) 1558-9455
    ISSN 1558-9447
    DOI 10.1177/15589447241233358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6820: Show issues Location:
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  3. Article: Understanding wound healing in obesity.

    Cotterell, Asha / Griffin, Michelle / Downer, Mauricio A / Parker, Jennifer B / Wan, Derrick / Longaker, Michael T

    World journal of experimental medicine

    2024  Volume 14, Issue 1, Page(s) 86898

    Abstract: Obesity has become more prevalent in the global population. It is associated with the development of several diseases including diabetes mellitus, coronary heart disease, and metabolic syndrome. There are a multitude of factors impacted by obesity that ... ...

    Abstract Obesity has become more prevalent in the global population. It is associated with the development of several diseases including diabetes mellitus, coronary heart disease, and metabolic syndrome. There are a multitude of factors impacted by obesity that may contribute to poor wound healing outcomes. With millions worldwide classified as obese, it is imperative to understand wound healing in these patients. Despite advances in the understanding of wound healing in both healthy and diabetic populations, much is unknown about wound healing in obese patients. This review examines the impact of obesity on wound healing and several animal models that may be used to broaden our understanding in this area. As a growing portion of the population identifies as obese, understanding the underlying mechanisms and how to overcome poor wound healing is of the utmost importance.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2764849-7
    ISSN 2220-315X
    ISSN 2220-315X
    DOI 10.5493/wjem.v14.i1.86898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Towards Development of a Non-Toxigenic

    Hughes, Jaime / Aston, Carl / Kelly, Michelle L / Griffin, Ruth

    Pharmaceutics

    2022  Volume 14, Issue 5

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    Language English
    Publishing date 2022-05-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics14051086
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  5. Article ; Online: Revving up possibilities: can psychostimulants enhance physical function in children with cerebral palsy?

    Novak, Iona / Jackman, Michelle / Griffin, Alexandra R / Blatch-Williams, Remy / Norfolk, Esther / Lind, Karin / Polybank, Daniel / Mc Namara, Maria

    Pediatric research

    2024  Volume 95, Issue 5, Page(s) 1184–1185

    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-023-03010-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 564: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 373: Show issues

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  6. Article: Understanding Tendon Fibroblast Biology and Heterogeneity.

    DiIorio, Sarah E / Young, Bill / Parker, Jennifer B / Griffin, Michelle F / Longaker, Michael T

    Biomedicines

    2024  Volume 12, Issue 4

    Abstract: Tendon regeneration has emerged as an area of interest due to the challenging healing process of avascular tendon tissue. During tendon healing after injury, the formation of a fibrous scar can limit tendon strength and lead to subsequent complications. ... ...

    Abstract Tendon regeneration has emerged as an area of interest due to the challenging healing process of avascular tendon tissue. During tendon healing after injury, the formation of a fibrous scar can limit tendon strength and lead to subsequent complications. The specific biological mechanisms that cause fibrosis across different cellular subtypes within the tendon and across different tendons in the body continue to remain unknown. Herein, we review the current understanding of tendon healing, fibrosis mechanisms, and future directions for treatments. We summarize recent research on the role of fibroblasts throughout tendon healing and describe the functional and cellular heterogeneity of fibroblasts and tendons. The review notes gaps in tendon fibrosis research, with a focus on characterizing distinct fibroblast subpopulations in the tendon. We highlight new techniques in the field that can be used to enhance our understanding of complex tendon pathologies such as fibrosis. Finally, we explore bioengineering tools for tendon regeneration and discuss future areas for innovation. Exploring the heterogeneity of tendon fibroblasts on the cellular level can inform therapeutic strategies for addressing tendon fibrosis and ultimately reduce its clinical burden.
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12040859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Preoperative dietitian-led Very Low Calorie Diet (VLCD) Clinic for adults living with obesity undergoing gynaecology, laparoscopic cholecystectomy and hernia repair procedures: a pilot parallel randomised controlled trial.

    Griffin, Sally B / Palmer, Michelle A / Strodl, Esben / Lai, Rainbow / Chuah, Teong L / Burstow, Matthew J / Ross, Lynda J

    The British journal of nutrition

    2024  Volume 131, Issue 8, Page(s) 1436–1446

    Abstract: Obesity can increase the risk of postoperative complications. Despite increased demand for patients living with obesity to lose weight prior to common surgical procedures, the impact of intentional weight loss on surgical outcomes is largely unknown. We ... ...

    Abstract Obesity can increase the risk of postoperative complications. Despite increased demand for patients living with obesity to lose weight prior to common surgical procedures, the impact of intentional weight loss on surgical outcomes is largely unknown. We aimed to conduct a pilot study to assess the feasibility of a full-scale randomised controlled trial (RCT) to examine the effect of preoperative dietitian-led Very Low Calorie Diet (VLCD) Clinic on surgical outcomes in gynaecology and general surgeries. Between August 2021 and January 2023, a convenience sample of adults living with obesity (BMI ≥ 30 kg/m
    MeSH term(s) Adult ; Female ; Humans ; Male ; Caloric Restriction/methods ; Cholecystectomy, Laparoscopic ; Gynecology ; Herniorrhaphy ; Nutritionists ; Obesity/complications ; Obesity/surgery ; Weight Loss
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/S0007114524000114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.184: Show issues Location:
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  8. Article ; Online: Short- and long-term outcomes associated with anal sacculectomy in dogs with massive apocrine gland anal sac adenocarcinoma.

    Griffin, Maureen A / Mayhew, Philipp D / Culp, William T N / Giuffrida, Michelle A / Telek, Stephanie / Singh, Ameet / Oblak, Michelle / Swanton, Emmett

    Journal of the American Veterinary Medical Association

    2023  Volume 261, Issue 10, Page(s) 1–8

    Abstract: Objective: To evaluate short- and long-term outcomes for dogs undergoing anal sacculectomy for massive (> 5 cm) apocrine gland anal sac adenocarcinoma (AGASACA).: Animals: 28 client-owned dogs with massive AGASACA.: Procedures: A retrospective ... ...

    Abstract Objective: To evaluate short- and long-term outcomes for dogs undergoing anal sacculectomy for massive (> 5 cm) apocrine gland anal sac adenocarcinoma (AGASACA).
    Animals: 28 client-owned dogs with massive AGASACA.
    Procedures: A retrospective multi-institutional study was performed. Pre-, intra-, and post-operative data was collected, and variables were statistically analyzed for associations with progression-free interval (PFI) and overall survival (OS).
    Results: At the time of anal sacculectomy, 19 (68%) dogs underwent concurrent iliosacral lymph node extirpation, including 17 of 18 (94%) dogs with suspected nodal metastasis preoperatively. Five (18%) dogs experienced grade 2 intraoperative complications. Ten (36%) dogs experienced postoperative complications, including 1 grade 3 and 1 grade 4 complication. No dogs had permanent fecal incontinence, tenesmus, or anal stenosis. Nineteen dogs received adjuvant chemotherapy, radiation, or both. Local recurrence occurred in 37% of dogs. Dogs with lymph node metastasis at surgery were more likely than dogs without metastasis to develop new/progressive lymph node metastasis (10/17 [59%] vs 0/10 [0%]; P = .003) and distant metastasis (7/17 [41%] vs 0/10 [0%]; P = .026). Median PFI was 204 days (95% CI, 145 to 392). Median OS was 671 days (95% CI, 225 to upper limit not reached). Nodal metastasis at the time of surgery was associated with shorter PFI (P = .017) but not OS (P = .26). Adjuvant therapy was not associated with outcome.
    Clinical relevance: Dogs with massive AGASACA experienced prolonged survival following anal sacculectomy despite a high incidence of local recurrence and metastasis. Lymph node metastasis at the time of surgery was a negative prognostic indicator for PFI but not OS.
    MeSH term(s) Animals ; Dogs ; Adenocarcinoma/surgery ; Adenocarcinoma/veterinary ; Adenocarcinoma/drug therapy ; Anal Gland Neoplasms/surgery ; Anal Gland Neoplasms/pathology ; Anal Sacs/surgery ; Anal Sacs/pathology ; Apocrine Glands/pathology ; Dog Diseases/pathology ; Lymphatic Metastasis/pathology ; Retrospective Studies
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.23.02.0102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Response.

    Kim, Alexia / Downer, Mauricio A / Berry, Charlotte E / Valencia, Caleb / Fazilat, Alex Z / Griffin, Michelle

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 12

    Abstract: Implantable biomaterials represent the forefront of regenerative medicine, providing platforms and vessels for delivering a creative range of therapeutic benefits in diverse disease contexts. However, the chronic damage resulting from implant rejection ... ...

    Abstract Implantable biomaterials represent the forefront of regenerative medicine, providing platforms and vessels for delivering a creative range of therapeutic benefits in diverse disease contexts. However, the chronic damage resulting from implant rejection tends to outweigh the intended healing benefits, presenting a considerable challenge when implementing treatment-based biomaterials. In response to implant rejection, proinflammatory macrophages and activated fibroblasts contribute to a synergistically destructive process of uncontrolled inflammation and excessive fibrosis. Understanding the complex biomaterial-host cell interactions that occur within the tissue microenvironment is crucial for the development of therapeutic biomaterials that promote tissue integration and minimize the foreign body response. Recent modifications of specific material properties enhance the immunomodulatory capabilities of the biomaterial and actively aid in taming the immune response by tuning interactions with the surrounding microenvironment either directly or indirectly. By incorporating modifications that amplify anti-inflammatory and pro-regenerative mechanisms, biomaterials can be optimized to maximize their healing benefits in harmony with the host immune system.
    Language English
    Publishing date 2023-12-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10121411
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  10. Article: Current Biomaterials for Wound Healing.

    Downer, Mauricio / Berry, Charlotte E / Parker, Jennifer B / Kameni, Lionel / Griffin, Michelle

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 12

    Abstract: Wound healing is the body's process of injury recovery. Skin healing is divided into four distinct overlapping phases: hemostasis, inflammation, proliferation, and remodeling. Cell-to-cell interactions mediated by both cytokines and chemokines are ... ...

    Abstract Wound healing is the body's process of injury recovery. Skin healing is divided into four distinct overlapping phases: hemostasis, inflammation, proliferation, and remodeling. Cell-to-cell interactions mediated by both cytokines and chemokines are imperative for the transition between these phases. Patients can face difficulties in the healing process due to the wound being too large, decreased vascularization, infection, or additional burdens of a systemic illness. The field of tissue engineering has been investigating biomaterials as an alternative for skin regeneration. Biomaterials used for wound healing may be natural, synthetic, or a combination of both. Once a specific biomaterial is selected, it acts as a scaffold for skin regeneration. When the scaffold is applied to a wound, it allows for the upregulation of distinct molecular signaling pathways important for skin repair. Although tissue engineering has made great progress, more research is needed in order to support the use of biomaterials for wound healing for clinical translation.
    Language English
    Publishing date 2023-11-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10121378
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