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  1. Article ; Online: Roles of Microglia in AD Pathology.

    Rong, Gao / Hongrong, Wu / Qingqi, Li / Jianfeng, Zhao

    Current Alzheimer research

    2023  Volume 19, Issue 13, Page(s) 854–869

    Abstract: Amyloid plaques and neurofibrillary tangles are two main characteristics of Alzheimer's disease (AD). As cerebral resident phagocytes, microglia have different roles in Aβ pathology and tau pathology. In this review, we discuss microglial functions in ... ...

    Abstract Amyloid plaques and neurofibrillary tangles are two main characteristics of Alzheimer's disease (AD). As cerebral resident phagocytes, microglia have different roles in Aβ pathology and tau pathology. In this review, we discuss microglial functions in the formation, clearance, and spread of Aβ and tau. Many receptors and enzymes, which are related to microglia, participate in AD pathologies and thus are thought to be potential targets of AD. So, making use of microglia can be beneficial to confine AD pathologies. To sum up, this article review the roles of microglia in AD pathology and possible corresponding treatments.
    MeSH term(s) Humans ; Alzheimer Disease/pathology ; Microglia/pathology ; Neurofibrillary Tangles/pathology ; Amyloid beta-Peptides ; tau Proteins
    Chemical Substances Amyloid beta-Peptides ; tau Proteins
    Language English
    Publishing date 2023-02-05
    Publishing country United Arab Emirates
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2205170-3
    ISSN 1875-5828 ; 1567-2050
    ISSN (online) 1875-5828
    ISSN 1567-2050
    DOI 10.2174/1567205020666230203112351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mesenteric laceration of the sigmoid colon after colonoscopy: A rare complication.

    Wu, Min / Lin, Yonghua / Chen, Zhichao / Wei, Jianfeng

    Asian journal of surgery

    2023  Volume 46, Issue 11, Page(s) 5391–5392

    MeSH term(s) Humans ; Colon, Sigmoid ; Lacerations ; Colonoscopy ; Colon
    Language English
    Publishing date 2023-08-01
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.07.091
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  3. Article ; Online: Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases.

    Wu, Xiurong / Yang, Zhang-Hua / Zheng, Yue / Wu, Jianfeng / Han, Jiahuai

    Cellular & molecular immunology

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country China
    Document type Letter
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-024-01162-w
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  4. Article ; Online: Ipsilateral orolingual angioedema following rhTNK-tPA administration for acute ischemic stroke.

    Shi, Guomei / Lv, Jianfeng / Wu, Weixiang / Zhou, Rujuan

    The American journal of emergency medicine

    2024  Volume 77, Page(s) 231.e1–231.e3

    Abstract: Recombinant human tenecteplase tissue-type plasminogen activator (rhTNK-tPA), a genetically modified variant of conventional alteplase with longer half-life and higher fibrin specificity, has now emerged as a reasonable choice for thrombolytic treatment ... ...

    Abstract Recombinant human tenecteplase tissue-type plasminogen activator (rhTNK-tPA), a genetically modified variant of conventional alteplase with longer half-life and higher fibrin specificity, has now emerged as a reasonable choice for thrombolytic treatment of acute ischemic stroke (AIS) in China. Orolingual angioedema is a rare but potentially life-threatening complication of intravenous thrombolysis. Currently, there is no documented evidence of orolingual angioedema occurring after thrombolysis with rhTNK-tPA. In this report, we present a unique case of a 75-year-old Chinese man who developed ipsilateral orolingual angioedema following the administration of rhTNK-tPA for AIS. Our case emphasizes the need for caution when using rhTNK-tPA due to its potential to induce ipsilateral orolingual angioedema.
    MeSH term(s) Male ; Humans ; Aged ; Stroke/drug therapy ; Stroke/complications ; Ischemic Stroke/drug therapy ; Tissue Plasminogen Activator/adverse effects ; Fibrinolytic Agents/adverse effects ; Administration, Intravenous ; Angioedema/chemically induced ; Angioedema/drug therapy ; Brain Ischemia/complications
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68) ; Fibrinolytic Agents
    Language English
    Publishing date 2024-01-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2024.01.026
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  5. Article ; Online: A commentary on 'Learning curves in laparoscopic distal pancreatectomy: a different experience for each generation (Int J Surg. 2023;109(6):1648-55)'.

    Wu, Min / Lin, Yonghua / Wei, Jianfeng

    International journal of surgery (London, England)

    2023  Volume 109, Issue 11, Page(s) 3707–3708

    MeSH term(s) Humans ; Pancreatectomy ; Learning Curve ; Pancreatic Neoplasms/surgery ; Adenocarcinoma/surgery ; Laparoscopy
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000000642
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  6. Article ; Online: Recent advance in modification strategies and applications of soy protein gel properties.

    Liang, Peijun / Chen, Simin / Fang, Xiang / Wu, Jianfeng

    Comprehensive reviews in food science and food safety

    2024  Volume 23, Issue 1, Page(s) e13276

    Abstract: Soy protein gel can be developed into a variety of products, ranging from traditional food (e.g., tofu) to newly developed food (e.g., soy yogurt and meat analog). So far, efforts are still needed to be made on modifying the gel properties of soy protein ...

    Abstract Soy protein gel can be developed into a variety of products, ranging from traditional food (e.g., tofu) to newly developed food (e.g., soy yogurt and meat analog). So far, efforts are still needed to be made on modifying the gel properties of soy protein for improving its sensory properties as animal protein-based food substitutes. Furthermore, there is always a need to regulate its gel properties for designing novel and tailored products of soy protein gels due to the fast-growing plant protein-based product market. This review gave an emphasis on the latest modification strategies and applications of gel properties of soy protein. The modifying methods of soy protein gel properties were reviewed from an aspect of composition or processing. Compositional modification included changing protein composition and gelling conditions and using additives, whereas processing strategies can be achieved through physical, chemical, and enzymatic treatments. Several compositional modification and processing strategies have been both proven to alter the gel properties of soy protein effectively. So far, soy protein gel has been applied in the field of food and biomedicine. In the future, more mechanistic studies on the modification methods are still needed to facilitate the full application of soy protein gel.
    MeSH term(s) Animals ; Soybean Proteins/chemistry ; Soy Foods ; Gels/chemistry ; Plant Proteins
    Chemical Substances Soybean Proteins ; Gels ; Plant Proteins
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2185829-9
    ISSN 1541-4337 ; 1541-4337
    ISSN (online) 1541-4337
    ISSN 1541-4337
    DOI 10.1111/1541-4337.13276
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  7. Article ; Online: Allergic bronchopulmonary mycosis due to Schizophyllum commune in a patient with chronic hepatitis B.

    Xu, Rui / Zhang, Jianfeng / Zheng, Jiangnan / Wu, Qiaozhen

    Journal of infection in developing countries

    2024  Volume 18, Issue 3, Page(s) 488–494

    Abstract: Introduction: Schizophyllum commune (S. commune) is an opportunistic pathogenic fungus and can cause infection of the respiratory system in immunocompromised hosts. Allergic bronchopulmonary mycosis (ABPM) is the major disease caused by S. commune. ... ...

    Abstract Introduction: Schizophyllum commune (S. commune) is an opportunistic pathogenic fungus and can cause infection of the respiratory system in immunocompromised hosts. Allergic bronchopulmonary mycosis (ABPM) is the major disease caused by S. commune. However, identification of S. commune using routine mycological diagnostic methods is difficult. It is easy to make mistakes in diagnosis and treatment, resulting in deterioration of the disease. We report the first case of ABPM due to S. commune in a Chinese patient with chronic hepatitis B.
    Case presentation: The patient presented cough, sputum and dyspnea for six months. The pathogen was missed during routine laboratory workup. We performed bronchoscopy examination and bronchoalveolar lavage. S. commune was identified by metagenomic next-generation sequencing (mNGS) of bronchial alveolar lavage fluid (BALF). Hence, the patient was immediately treated with 200 mg voriconazole twice daily (intravenous infusion) and 20 mg prednisone once a day (oral therapy), along with oral entecavir for hepatitis B. There was no recurrence of infection after the medication was discontinued.
    Conclusions: S. commune infection should be considered in the diagnosis of patients with refractory cough, sputum and dyspnea, especially in immunocompromised individuals. The mNGS technique is an effective supplementary technique for the diagnosis of S. commune infection, enabling precise clinical decision-making and appropriate treatment. Most patients have good prognosis with a combination of proper antifungal therapy and hormonal therapy.
    MeSH term(s) Humans ; Invasive Pulmonary Aspergillosis/diagnosis ; Invasive Pulmonary Aspergillosis/drug therapy ; Schizophyllum ; Hepatitis B, Chronic/complications ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/drug therapy ; Dyspnea ; Cough
    Language English
    Publishing date 2024-03-31
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.18024
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  8. Article ; Online: Chiral phosphoric acid-catalyzed enantioselective [5+1] cycloaddition reaction of

    Yu, Jiulong / Wu, Jinyu / Zhu, Yu / Xiong, Dong / Yang, Lin / Li, Jun / Zheng, Jianfeng

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 19, Page(s) 2637–2640

    Abstract: The first catalytic enantioselective [5+1] cycloaddition reactions ... ...

    Abstract The first catalytic enantioselective [5+1] cycloaddition reactions of
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc05890e
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  9. Article: Corrigendum: The effect of acupuncture at the

    Su, Kangna / Wang, Lihan / Wang, Zhongqing / Ma, Jiayao / Zhang, Chao / Bi, Hongsheng / Wu, Jianfeng

    Frontiers in integrative neuroscience

    2024  Volume 18, Page(s) 1367593

    Abstract: This corrects the article DOI: 10.3389/fnint.2023.1234471.]. ...

    Abstract [This corrects the article DOI: 10.3389/fnint.2023.1234471.].
    Language English
    Publishing date 2024-03-15
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2452962-X
    ISSN 1662-5145
    ISSN 1662-5145
    DOI 10.3389/fnint.2024.1367593
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  10. Article ; Online: Integrated SEAWAT model and GALDIT method for dynamic vulnerability assessment of coastal aquifer to seawater intrusion.

    Lyu, Panpan / Song, Jian / Yin, Ziyue / Wu, Jianfeng / Wu, Jichun

    The Science of the total environment

    2024  Volume 925, Page(s) 171740

    Abstract: Seawater intrusion (SI) has become a global issue exacerbated by intense anthropogenic activities and climate change. It is imperative to seek a synergistic strategy to reconcile environmental and economic benefits in the coastal regions. However, the ... ...

    Abstract Seawater intrusion (SI) has become a global issue exacerbated by intense anthropogenic activities and climate change. It is imperative to seek a synergistic strategy to reconcile environmental and economic benefits in the coastal regions. However, the intricate SI process and data scarcity present formidable challenges in dynamically assessing the coastal groundwater vulnerability. To address the challenge, this study proposed a novel framework that integrates the existing vulnerability assessment method (GALDIT) and variable-density groundwater model (SEAWAT). The future scenarios from 2019 to 2050 were investigated monthly under climate change (SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5) and human activities (80 % and 50 % of current groundwater abstraction) in Longkou city, China, a typical coastal region subject to extensive SI, compared with the status quo in 2018. Results indicated that by 2050, the high vulnerability area, is in a narrow buffer within 1.2 km from the shoreline and exhibits minor changes while the salt concentration here increased by about 2700 mg/L compared with the current situation. The moderate vulnerability zone expands by about 30 km
    Language English
    Publishing date 2024-03-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171740
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