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  1. Article: Prevalence of Hyperglycemia in Pregnancy and Related Screening Practices in Rural Dehradun: The First Population-Based Study from Uttarakhand (PGDRD-1).

    Mishra, Surabhi / Semwal, Jayanti / Srivastava, Abhay / Kumar Mishra, Surendra

    Indian journal of endocrinology and metabolism

    2023  Volume 27, Issue 2, Page(s) 145–153

    Abstract: Aims: Phase I of the : Methods: Using a multistage random sampling technique, 1,223 pregnant women locally registered in the rural field practice area of a block were identified. Those requiring HIP screening were subjected to a 2-h 75 g oral glucose ...

    Abstract Aims: Phase I of the
    Methods: Using a multistage random sampling technique, 1,223 pregnant women locally registered in the rural field practice area of a block were identified. Those requiring HIP screening were subjected to a 2-h 75 g oral glucose tolerance test during the house visit irrespective of their period-of-gestation and last meal timings, diagnosed using the Diabetes in Pregnancy Study Group India (DIPSI) criterion (when indicated). Data were collected by personal interviews using a pretested data collection tool. Statistical Package for Social Sciences version 20.0 was used for analysis.
    Results: The overall HIP prevalence recorded was 9.7% (95% CI: 8.1-11.5%); the majority (95.8%) were GDM followed by overt DIP (4.2%). Less than 1% of the subjects (0.7%) self-reported pre-GDM. Despite this burden, more than three-fourths were never screened for HIP in their pregnancy. Of those tested, the majority availed secondary healthcare facilities. Few even had to bear expenses in private with a very handful being tested free-of-cost by ANM in the community; findings that altogether sharply contrast to those recommended by national protocols.
    Conclusion: Despite the high HIP burden, beneficiaries are unable to utilize community-related universal screening protocols as desired.
    Language English
    Publishing date 2023-04-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2600211-5
    ISSN 2230-9500 ; 2230-8210
    ISSN (online) 2230-9500
    ISSN 2230-8210
    DOI 10.4103/ijem.ijem_459_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Assessment of sanitation and drinking water facilities among slum households in Bhubaneswar, Odisha - A cross-sectional study.

    Alice, Alice / Behera, Deepanjali / Behera, Manas Ranjan / Patra, Shantanu Kumar / Mishra, Jayanti

    Journal of family medicine and primary care

    2023  Volume 12, Issue 3, Page(s) 484–492

    Abstract: Aim: The study aims to assess the practice of using unsafe drinking water and sanitary practices among the population dwelling in slum settings of Bhubaneswar city, Odisha, India.: Subjects and methods: A cross-sectional study was conducted among 288 ...

    Abstract Aim: The study aims to assess the practice of using unsafe drinking water and sanitary practices among the population dwelling in slum settings of Bhubaneswar city, Odisha, India.
    Subjects and methods: A cross-sectional study was conducted among 288 households in the Bhubaneswar slums of Chandrasekharpur, Neeladri Vihar, and Trinatha basti. A questionnaire was administered face to face. Descriptive statistics were used to define the participants' sociodemographic characteristics, household information, drinking water, latrine characteristics, and waste disposal.
    Results: The majority (59.7%) resided in kutcha households in notified slum areas, and 89.6% were reportedly illiterate. About 92.7% resided in a deplorable condition, relying on piped water (79.5%) from the community sources and 20.5% used it for drinking and household purposes. Around 83% of the respondents stated they did not treat water before consumption. Bathroom facilities were found to be inadequate, and 74.3% used pit latrines. The majority of household wastes (83%) were managed by directly letting them to the drainage system untreated. As a consequence, 91% reported breeding of flies and mosquitoes near their household premises and 70.5% stated having fever in the past 6 months.
    Conclusion: Despite the government's initiatives to improve water, sanitation, and hygiene (WASH) strategies, an extensive gap in practice was observed. As a result, Bhubaneswar municipality must strictly enforce policy and regulatory guidelines concerning WASH to improve the sanitation practices, particularly in the areas of drinking water and household waste management.
    Language English
    Publishing date 2023-03-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_1544_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Maladaptive Behavior and Associated Factors among Young Children with Autism.

    Samanta, Priyadarsini / Panigrahi, Ansuman / Senapati, Laxman Kumar / Mishra, Durga Prasad / Ravan, Jayaprakash Russel / Mishra, Jayanti

    Indian journal of pediatrics

    2022  Volume 89, Issue 11, Page(s) 1134–1136

    Abstract: The present study assessed the prevalence of clinically significant maladaptive behaviors and associated factors among young male children diagnosed with autism. A cross-sectional study including mothers of 88 male children with autism aged 2 to 5 y old ... ...

    Abstract The present study assessed the prevalence of clinically significant maladaptive behaviors and associated factors among young male children diagnosed with autism. A cross-sectional study including mothers of 88 male children with autism aged 2 to 5 y old was conducted in the year 2019. Using the Child Behavior Checklist (CBCL), mothers rated their child's maladaptive behaviors. CBCL overall scores in the clinically relevant range were found in 76 (86.4%) children with autism (87.5% and 42% children had clinically significant internalizing and externalizing problems, respectively). Withdrawn (94.3%), attention problems (60.2%), and sleep problems (53.4%) were the predominant CBCL syndrome scales. Sociodemographic factors like autism severity and caffeine consumption were found to be significantly associated with maladaptive behaviors. There is an urgent need for designing effective behavioral management strategies incorporating various risk factors to enhance the quality of life among these vulnerable children.
    MeSH term(s) Autistic Disorder/epidemiology ; Caffeine ; Child ; Child Behavior Disorders ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Male ; Quality of Life
    Chemical Substances Caffeine (3G6A5W338E)
    Language English
    Publishing date 2022-08-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-022-04286-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Highly selective and sensitive simultaneous nanomolar detection of Cs(i) and Al(iii) ions using tripodal organic nanoparticles in aqueous media: the effect of the urea backbone on chemosensing.

    Mishra, Jayanti / Kaur, Manpreet / Kaur, Navneet / Ganguli, Ashok K

    RSC advances

    2020  Volume 10, Issue 38, Page(s) 22691–22700

    Abstract: Chemosensing plays a very important role in the detection of essential/pollutant ions in aqueous media. In this manuscript, two tripodal ligands, ...

    Abstract Chemosensing plays a very important role in the detection of essential/pollutant ions in aqueous media. In this manuscript, two tripodal ligands,
    Language English
    Publishing date 2020-06-15
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d0ra03171b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Heart Rate Variability in Unexplained Syncope Patients Versus Healthy Controls: A Comparative Study.

    Dash, Rashmi R / Samanta, Priyadarsini / Das, Susnato / Jena, Anupam / Panda, Bandita / Parida, Barsha B / Mishra, Jayanti

    Cureus

    2023  Volume 15, Issue 7, Page(s) e41370

    Abstract: Background Syncope or fainting is the sudden and transient loss of consciousness. This could lead to an increase in mortality due to sudden cardiac death or comorbidity in these patients. Heart rate variability (HRV) is a noninvasive bedside procedure ... ...

    Abstract Background Syncope or fainting is the sudden and transient loss of consciousness. This could lead to an increase in mortality due to sudden cardiac death or comorbidity in these patients. Heart rate variability (HRV) is a noninvasive bedside procedure for assessing the cardiovascular autonomic function. There may be an abnormal alteration in the HRV parameters in syncope patients. This can be used for looking into cardiovascular autonomic changes in syncope. This would help in early diagnosis and intervention. Objective The aim of this present study was to compare the HRV parameters between unexplained syncope patients and age-matched healthy controls and to find a correlation between HRV parameters and cardiovascular parameters like pulse and mean blood pressure. Materials and methods A five-minute continuous electrocardiogram (ECG) was recorded and HRV analysis was done by ADInstruments' PowerLab (Oxford, United Kingdom) for 25 cases and 25 controls. Results The mean standard deviation of the RR interval (SDRR) in milliseconds was found to be significantly lower in the cases (21.93 ± 3.53) as compared to controls (71.27 ± 27.40). The mean value of the low-frequency to high-frequency ratio (LF/HF) was significantly higher in cases (1.43 ± 0.40) as compared to controls (0.98 ± 1.07). However, there was no significant correlation between the pulse, blood pressure, and HRV measures. Conclusion The findings suggest a sympathetic predominance in the cases of unexplained syncope as compared to the controls.
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.41370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Sleep quality and associated factors among undergraduate medical students during Covid-19 confinement.

    Mishra, Jayanti / Panigrahi, Ansuman / Samanta, Priyadarsini / Dash, Kulumina / Mahapatra, Pranab / Behera, Manas Ranjan

    Clinical epidemiology and global health

    2022  Volume 15, Page(s) 101004

    Abstract: Problem considered: Medical students are vulnerable to poor sleep quality which may lead to attention difficulties and poor academic performance. Good quality sleep is needed for optimal neurocognitive and psychomotor functions as well as physical and ... ...

    Abstract Problem considered: Medical students are vulnerable to poor sleep quality which may lead to attention difficulties and poor academic performance. Good quality sleep is needed for optimal neurocognitive and psychomotor functions as well as physical and mental health. This study aimed to assess the prevalence of poor sleep quality among undergraduate medical students during home confinement at the time of Covid-19 pandemic and analyze the relationship between sleep quality and relevant socio-demographic and psychological variables.
    Methods: A cross-sectional study was conducted among 284 undergraduate medical students of a teaching hospital of Bhubaneswar from October-November 2020. Using a semi-structured questionnaire, relevant information was collected. Sleep quality of the students was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire and mental health status of the students using Depression, Anxiety, and Stress Scale - 21 (DASS-21).
    Results: The prevalence of poor sleep quality among undergraduate medical students was 45%. Multivariate logistic regression revealed that students doing exercise for <3 days/week (AOR: 1.81, 95% CI: 1.01-3.23), spending ≥8 h screen time/day (AOR: 2.02, 95%: 1.12-3.66), having anxiety symptoms (AOR: 3.61, 95% CI: 1.72-7.57), and those who were not satisfied with own self (AOR: 2.69, 95% CI: 1.35-5.38) were more likely to report poor sleep quality.
    Conclusion: Poor sleep quality was prevalent among undergraduate medical students during their home confinement at the time of Covid-19 pandemic. Sleep educational programs, anxiety management, and lifestyle modifications can be recommended to improve sleep quality among medical students.
    Language English
    Publishing date 2022-03-11
    Publishing country India
    Document type Journal Article
    ISSN 2452-0918
    ISSN 2452-0918
    DOI 10.1016/j.cegh.2022.101004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Elucidating the Drug Repurposing Spectra of COVID-19 with its Analogues SARS and MERS.

    Mishra, Jayanti / Prasun, Chakrawarti / Sahoo, Pravat K / Nair, Maya S

    Mini reviews in medicinal chemistry

    2021  Volume 21, Issue 20, Page(s) 3191–3202

    Abstract: Corona Virus Disease-2019 (COVID-19), caused by the SARS CoV-2 virus, has been announced as a pandemic by the World Health Organization. COVID-19 has affected people globally, infecting more than 39.8 million people and claiming up to 1.11 million lives, ...

    Abstract Corona Virus Disease-2019 (COVID-19), caused by the SARS CoV-2 virus, has been announced as a pandemic by the World Health Organization. COVID-19 has affected people globally, infecting more than 39.8 million people and claiming up to 1.11 million lives, yet there is no effective treatment strategy to cure this disease. As vaccine development is a time-consuming process, currently, efforts are being made to develop alternative plans for the timely and effective management of this disease. Drug repurposing always fascinated researchers and can be utilized as the most acceptable alternative to develop the therapeutics for COVID-19 using the pre-approved drugs. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has shown resemblance with distinctive enzyme targets, such as 3CLpro/Mpro, RdRp, Cathepsin L, and TMPRSS2 present in SARS CoV and MERS CoV. Therefore, the drugs that have shown efficacy in these viruses can also be used for the treatment of COVID-19. This review focuses on why repurposing could provide a better alternative in COVID- 19 treatment. The similarity in the structure and progression of infection of SARS CoV and MERS viruses offers a direction and validation to evaluate the drugs approved for SARS and MERS against COVID-19. It has been indicated that multiple therapeutic options that demonstrate efficacy against SARS CoV 2 are available to mitigate the potential emergence of COVID-19 infection.
    MeSH term(s) Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Coronavirus Infections/drug therapy ; Drug Repositioning ; Humans ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Middle East Respiratory Syndrome Coronavirus/enzymology ; SARS Virus/drug effects ; SARS Virus/enzymology ; SARS-CoV-2/drug effects ; SARS-CoV-2/enzymology ; Severe Acute Respiratory Syndrome/drug therapy
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-02-22
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2104081-3
    ISSN 1875-5607 ; 1389-5575
    ISSN (online) 1875-5607
    ISSN 1389-5575
    DOI 10.2174/1389557521666210225114733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Sleep quality and associated factors among undergraduate medical students during Covid-19 confinement

    Jayanti Mishra / Ansuman Panigrahi / Priyadarsini Samanta / Kulumina Dash / Pranab Mahapatra / Manas Ranjan Behera

    Clinical Epidemiology and Global Health, Vol 15, Iss , Pp 101004- (2022)

    2022  

    Abstract: Problem considered: Medical students are vulnerable to poor sleep quality which may lead to attention difficulties and poor academic performance. Good quality sleep is needed for optimal neurocognitive and psychomotor functions as well as physical and ... ...

    Abstract Problem considered: Medical students are vulnerable to poor sleep quality which may lead to attention difficulties and poor academic performance. Good quality sleep is needed for optimal neurocognitive and psychomotor functions as well as physical and mental health. This study aimed to assess the prevalence of poor sleep quality among undergraduate medical students during home confinement at the time of Covid-19 pandemic and analyze the relationship between sleep quality and relevant socio-demographic and psychological variables. Methods: A cross-sectional study was conducted among 284 undergraduate medical students of a teaching hospital of Bhubaneswar from October–November 2020. Using a semi-structured questionnaire, relevant information was collected. Sleep quality of the students was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire and mental health status of the students using Depression, Anxiety, and Stress Scale - 21 (DASS-21). Results: The prevalence of poor sleep quality among undergraduate medical students was 45%. Multivariate logistic regression revealed that students doing exercise for <3 days/week (AOR: 1.81, 95% CI: 1.01–3.23), spending ≥8 h screen time/day (AOR: 2.02, 95%: 1.12–3.66), having anxiety symptoms (AOR: 3.61, 95% CI: 1.72–7.57), and those who were not satisfied with own self (AOR: 2.69, 95% CI: 1.35–5.38) were more likely to report poor sleep quality. Conclusion: Poor sleep quality was prevalent among undergraduate medical students during their home confinement at the time of Covid-19 pandemic. Sleep educational programs, anxiety management, and lifestyle modifications can be recommended to improve sleep quality among medical students.
    Keywords DASS-21 ; Home confinement ; Medical students ; Sleep quality ; Covid-19 pandemic ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Bacteriological Profile and Outcome of Culture-Positive Neonatal Sepsis in a Special Newborn Care Unit Setting, Odisha.

    Mohakud, Nirmal K / Mishra, Jyoti P / Nayak, Manas K / Mishra, Jayanti / Pradhan, Lingaraj / Panda, Subhra Snigdha / Bahera, Manas Ranjan / Pugulia, Rishabh

    Cureus

    2022  Volume 14, Issue 5, Page(s) e25539

    Abstract: Introduction: Nearly one-third of neonatal mortality in India is due to neonatal sepsis and death occurs in 30% of culture-positive neonates. Pathogens such as : Materials and methods: It was an observational study, conducted in special newborn care ... ...

    Abstract Introduction: Nearly one-third of neonatal mortality in India is due to neonatal sepsis and death occurs in 30% of culture-positive neonates. Pathogens such as 
    Materials and methods: It was an observational study, conducted in special newborn care units (SNCUs) of Capital Hospital in Bhubaneswar, Odisha from May 2017 to October 2019. All neonates (<28 days of life) with blood culture-positive sepsis were included in this study. Blood cultures were sent in all the babies with features of clinical sepsis. The demographic profile of neonates, clinical presentations, isolated organisms, and their sensitive patterns was recorded for analysis.
    Results: Blood culture was sent in 445 suspected neonates with clinical sepsis out of which 115 blood culture positive organisms were isolated. Among the isolated organisms, 42 (35.6%) cases were 
    Conclusion:
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.25539
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  10. Article ; Online: Body composition changes and its association with dyslipidemia in patients receiving hemodialysis

    Priyadarsini Samanta / Debdattaa Bhattacharyya / Ansuman Panigrahi / Soumya Mishra / Jayanti Mishra / Laxman Kumar Senapati

    Clinical Epidemiology and Global Health, Vol 10, Iss , Pp 100686- (2021)

    2021  

    Abstract: Problem considered: The study aimed to assess the body composition changes after dialysis in chronic kidney disease (CKD) patients undergoing hemodialysis and to determine the strengths of relationships between various body composition parameters and ... ...

    Abstract Problem considered: The study aimed to assess the body composition changes after dialysis in chronic kidney disease (CKD) patients undergoing hemodialysis and to determine the strengths of relationships between various body composition parameters and blood lipid levels in these patients. Methods: The cross-sectional study was conducted during May–September 2019 involving 97 patients (58 males and 39 females, age: 40–70 years) of CKD undergoing maintenance hemodialysis. The multifrequency bioelectrical impedance analyzer was used to measure various body composition parameters like body fat percent, lean mass percent, body mass index, body fat mass index, fat-free mass index, total body water percent, extracellular water percent, intracellular water percent, nutrition index, prediction marker, basal metabolic rate, and estimated average energy requirement. Blood lipid levels were collected from the patients’ clinical records. Results: All the body composition parameters except nutrition index and prediction marker differed significantly before and after dialysis. Various body composition parameters were significantly correlated with one or more lipid levels before and after dialysis. Conclusion: The body composition parameters change significantly after hemodialysis among CKD patients. Our findings suggest that body composition parameters, whether measured before or after dialysis could be useful in assessing dyslipidemia in patients receiving hemodialysis.
    Keywords Bioelectrical impedance ; Blood lipid ; Body composition ; Chronic kidney disease ; Hemodialysis ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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