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Article ; Online: Resistive Memory-Switching Behavior in Solution-Processed Trans, trans-1,4-bis-(2-(2-naphthyl)-2-(butoxycarbonyl)-vinyl) Benzene-PVA-Composite-Based Aryl Acrylate on ITO-Coated PET.

Kamath, Rachana / Sarkar, Parantap / Melanthota, Sindhoora Kaniyala / Biswas, Rajib / Mazumder, Nirmal / De, Shounak

2024 Volume 16, Issue 2

Abstract: Resistive switching memories are among the emerging next-generation technologies that are possible candidates for in-memory and neuromorphic computing. In this report, resistive memory-switching behavior in solution-processed trans, trans-1,4-bis-(2-(2- ... ...

Abstract	Resistive switching memories are among the emerging next-generation technologies that are possible candidates for in-memory and neuromorphic computing. In this report, resistive memory-switching behavior in solution-processed trans, trans-1,4-bis-(2-(2-naphthyl)-2-(butoxycarbonyl)-vinyl) benzene-PVA-composite-based aryl acrylate on an ITO-coated PET device was studied. A sandwich configuration was selected, with silver (Ag) serving as a top contact and trans, trans-1,4-bis-(2-(2-naphthyl)-2-(butoxycarbonyl)-vinyl) benzene-PVA-composite-based aryl acrylate and ITO-PET serving as a bottom contact. The current-voltage (I-V) characteristics showed hysteresis behavior and non-zero crossing owing to voltages sweeping from positive to negative and vice versa. The results showed non-zero crossing in the devices' current-voltage (I-V) characteristics due to the nanobattery effect or resistance, capacitive, and inductive effects. The device also displayed a negative differential resistance (NDR) effect. Non-volatile storage was feasible with non-zero crossing due to the exhibition of resistive switching behavior. The sweeping range was -10 V to +10 V. These devices had two distinct states: 'ON' and 'OFF'. The ON/OFF ratios of the devices were 14 and 100 under stable operating conditions. The open-circuit voltages (Voc) and short-circuit currents (Isc) corresponding to memristor operation were explained. The DC endurance was stable. Ohmic conduction and direct tunneling mechanisms with traps explained the charge transport model governing the resistive switching behavior. This work gives insight into data storage in terms of a new conception of electronic devices based on facile and low-temperature processed material composites for emerging computational devices.
Language	English
Publishing date	2024-01-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym16020218
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Deep learning-based image processing in optical microscopy.

Melanthota, Sindhoora Kaniyala / Gopal, Dharshini / Chakrabarti, Shweta / Kashyap, Anirudh Ameya / Radhakrishnan, Raghu / Mazumder, Nirmal

Biophysical reviews

2022 Volume 14, Issue 2, Page(s) 463–481

Language	English
Publishing date	2022-04-06
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2486483-3
ISSN	1867-2469 ; 1867-2450
ISSN (online)	1867-2469
ISSN	1867-2450
DOI	10.1007/s12551-022-00949-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Spectroscopic methods for assessment of hand sanitizers.

Banik, Soumyabrata / Melanthota, Sindhoora Kaniyala / Vannathan, Anjana Anandan / Mahato, Krishna Kishore / Mal, Sib Sankar / Mazumder, Nirmal

Chemicke zvesti

2022 Volume 76, Issue 8, Page(s) 4907–4918

Abstract: Sanitization of inanimate objects or body surfaces using disinfectant is essential for eliminating disease-causing pathogens and maintaining personal hygiene. With the advent of health emergencies, the importance and high demand for hand sanitizers (HS) ... ...

Abstract	Sanitization of inanimate objects or body surfaces using disinfectant is essential for eliminating disease-causing pathogens and maintaining personal hygiene. With the advent of health emergencies, the importance and high demand for hand sanitizers (HS) are observed in everyday life. It is also important to know the constituent added to formulate HS, as the presence of harsh chemicals can cause skin irritation. In this study, different spectroscopic techniques were used to assess several commercially available HS along with the in-house prepared HS as per the WHO protocol. Fourier transform infrared spectroscopy and Raman spectroscopy identified the different HS chemical bonds and quantified the amount of alcohol and water in the HS. Varying amount of alcohols in HS, calibration profile was generated to identify its amount in commercial samples. Further, the commercial samples were also checked for contaminants whose presence in the HS might bring down its sanitization efficacy. Supplementary information: The online version contains supplementary material available at 10.1007/s11696-022-02208-x.
Language	English
Publishing date	2022-04-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2252770-9
ISSN	1336-9075 ; 0366-6352
ISSN (online)	1336-9075
ISSN	0366-6352
DOI	10.1007/s11696-022-02208-x
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Article ; Online: Light emitting diode (LED) based fluorescence microscopy for tuberculosis detection: a review.

Ojha, Anushka / Banik, Soumyabrata / Melanthota, Sindhoora Kaniyala / Mazumder, Nirmal

Lasers in medical science

2020 Volume 35, Issue 6, Page(s) 1431–1437

Abstract: Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the ... ...

Abstract	Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smear examination using conventional light microscopy is often the only resort for diagnosing TB. However, fluorescence microscopy is used as standard in most high-income countries, owing to its increased sensitivity. Light-emitting diodes (LEDs), being inexpensive, are increasingly gaining popularity as an alternative light source for fluorescence microscopy. It has been found to be highly efficient and has a lot of advantages over the conventional Ziehl-Neelsen-based bright field microscopy. In this review, we discuss about the usefulness of LED-based fluorescence microscopy in diagnosing TB and how it is superior to the other sources of light used.
MeSH term(s)	Actin Cytoskeleton/metabolism ; Coloring Agents ; Humans ; Microscopy, Fluorescence ; Optics and Photonics ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/microbiology
Chemical Substances	Coloring Agents
Language	English
Publishing date	2020-01-03
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	632808-8
ISSN	1435-604X ; 0268-8921
ISSN (online)	1435-604X
ISSN	0268-8921
DOI	10.1007/s10103-019-02947-6
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Article ; Online: Types of spectroscopy and microscopy techniques for cancer diagnosis: a review.

Kaniyala Melanthota, Sindhoora / Kistenev, Yury V / Borisova, Ekaterina / Ivanov, Deyan / Zakharova, Olga / Boyko, Andrey / Vrazhnov, Denis / Gopal, Dharshini / Chakrabarti, Shweta / K, Shama Prasada / Mazumder, Nirmal

Lasers in medical science

2022 Volume 37, Issue 8, Page(s) 3067–3084

Abstract: Cancer is a life-threatening disease that has claimed the lives of many people worldwide. With the current diagnostic methods, it is hard to determine cancer at an early stage, due to its versatile nature and lack of genomic biomarkers. The rapid ... ...

Abstract	Cancer is a life-threatening disease that has claimed the lives of many people worldwide. With the current diagnostic methods, it is hard to determine cancer at an early stage, due to its versatile nature and lack of genomic biomarkers. The rapid development of biophotonics has emerged as a potential tool in cancer detection and diagnosis. Using the fluorescence, scattering, and absorption characteristics of cells and tissues, it is possible to detect cancer at an early stage. The diagnostic techniques addressed in this review are highly sensitive to the chemical and morphological changes in the cell and tissue during disease progression. These changes alter the fluorescence signal of the cell/tissue and are detected using spectroscopy and microscopy techniques including confocal and two-photon fluorescence (TPF). Further, second harmonic generation (SHG) microscopy reveals the morphological changes that occurred in non-centrosymmetric structures in the tissue, such as collagen. Again, Raman spectroscopy is a non-destructive method that provides a fingerprinting technique to differentiate benign and malignant tissue based on Raman signal. Photoacoustic microscopy and spectroscopy of tissue allow molecule-specific detection with high spatial resolution and penetration depth. In addition, terahertz spectroscopic studies reveal the variation of tissue water content during disease progression. In this review, we address the applications of spectroscopic and microscopic techniques for cancer detection based on the optical properties of the tissue. The discussed state-of-the-art techniques successfully determines malignancy to its rapid diagnosis.
MeSH term(s)	Biomarkers ; Collagen ; Disease Progression ; Humans ; Microscopy/methods ; Neoplasms/diagnostic imaging ; Spectrum Analysis, Raman ; Water
Chemical Substances	Biomarkers ; Water (059QF0KO0R) ; Collagen (9007-34-5)
Language	English
Publishing date	2022-07-14
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	632808-8
ISSN	1435-604X ; 0268-8921
ISSN (online)	1435-604X
ISSN	0268-8921
DOI	10.1007/s10103-022-03610-3
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Article ; Online: Recent trends in smartphone-based detection for biomedical applications: a review.

Banik, Soumyabrata / Melanthota, Sindhoora Kaniyala / Arbaaz / Vaz, Joel Markus / Kadambalithaya, Vishak Madhwaraj / Hussain, Iftak / Dutta, Sibasish / Mazumder, Nirmal

Analytical and bioanalytical chemistry

2021 Volume 413, Issue 9, Page(s) 2389–2406

Abstract: Smartphone-based imaging devices (SIDs) have shown to be versatile and have a wide range of biomedical applications. With the increasing demand for high-quality medical services, technological interventions such as portable devices that can be used in ... ...

Abstract	Smartphone-based imaging devices (SIDs) have shown to be versatile and have a wide range of biomedical applications. With the increasing demand for high-quality medical services, technological interventions such as portable devices that can be used in remote and resource-less conditions and have an impact on quantity and quality of care. Additionally, smartphone-based devices have shown their application in the field of teleimaging, food technology, education, etc. Depending on the application and imaging capability required, the optical arrangement of the SID varies which enables them to be used in multiple setups like bright-field, fluorescence, dark-field, and multiple arrays with certain changes in their optics and illumination. This comprehensive review discusses the numerous applications and development of SIDs towards histopathological examination, detection of bacteria and viruses, food technology, and routine diagnosis. Smartphone-based devices are complemented with deep learning methods to further increase the efficiency of the devices. Graphical Abstract.
MeSH term(s)	Animals ; Biosensing Techniques/instrumentation ; Biosensing Techniques/methods ; Deep Learning ; Humans ; Immunoassay/instrumentation ; Immunoassay/methods ; Microscopy/instrumentation ; Microscopy/methods ; Optical Imaging/instrumentation ; Optical Imaging/methods ; Point-of-Care Systems ; Smartphone/instrumentation
Language	English
Publishing date	2021-02-15
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	201093-8
ISSN	1618-2650 ; 0016-1152 ; 0372-7920
ISSN (online)	1618-2650
ISSN	0016-1152 ; 0372-7920
DOI	10.1007/s00216-021-03184-z
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Article ; Online: Elucidating the microscopic and computational techniques to study the structure and pathology of SARS-CoVs.

Kaniyala Melanthota, Sindhoora / Banik, Soumyabrata / Chakraborty, Ishita / Pallen, Sparsha / Gopal, Dharshini / Chakrabarti, Shweta / Mazumder, Nirmal

Microscopy research and technique

2020 Volume 83, Issue 12, Page(s) 1623–1638

Abstract: Severe Acute Respiratory Syndrome Coronaviruses (SARS-CoVs), causative of major outbreaks in the past two decades, has claimed many lives all over the world. The virus effectively spreads through saliva aerosols or nasal discharge from an infected person. ...

Abstract	Severe Acute Respiratory Syndrome Coronaviruses (SARS-CoVs), causative of major outbreaks in the past two decades, has claimed many lives all over the world. The virus effectively spreads through saliva aerosols or nasal discharge from an infected person. Currently, no specific vaccines or treatments exist for coronavirus; however, several attempts are being made to develop possible treatments. Hence, it is important to study the viral structure and life cycle to understand its functionality, activity, and infectious nature. Further, such studies can aid in the development of vaccinations against this virus. Microscopy plays an important role in examining the structure and topology of the virus as well as pathogenesis in infected host cells. This review deals with different microscopy techniques including electron microscopy, atomic force microscopy, fluorescence microscopy as well as computational methods to elucidate various prospects of this life-threatening virus.
MeSH term(s)	Animals ; Chlorocebus aethiops ; Computational Biology/methods ; Coronavirus Infections/virology ; Host-Pathogen Interactions ; Humans ; Microscopy/classification ; Microscopy/methods ; Microscopy, Atomic Force ; Microscopy, Electron ; Microscopy, Electron, Scanning ; Microscopy, Fluorescence ; Severe acute respiratory syndrome-related coronavirus/chemistry ; Severe acute respiratory syndrome-related coronavirus/pathogenicity ; Severe acute respiratory syndrome-related coronavirus/ultrastructure ; Spike Glycoprotein, Coronavirus/chemistry ; Vero Cells
Chemical Substances	Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-08-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1099714-3
ISSN	1097-0029 ; 1059-910X
ISSN (online)	1097-0029
ISSN	1059-910X
DOI	10.1002/jemt.23551
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Article: Recent trends in smartphone-based detection for biomedical applications: a review

Banik, Soumyabrata / Melanthota, Sindhoora Kaniyala / Arbaaz / Vaz, Joel Markus / Kadambalithaya, Vishak Madhwaraj / Hussain, Iftak / Dutta, Sibasish / Mazumder, Nirmal

Analytical and bioanalytical chemistry. 2021 Apr., v. 413, no. 9

2021

Abstract	Smartphone-based imaging devices (SIDs) have shown to be versatile and have a wide range of biomedical applications. With the increasing demand for high-quality medical services, technological interventions such as portable devices that can be used in remote and resource-less conditions and have an impact on quantity and quality of care. Additionally, smartphone-based devices have shown their application in the field of teleimaging, food technology, education, etc. Depending on the application and imaging capability required, the optical arrangement of the SID varies which enables them to be used in multiple setups like bright-field, fluorescence, dark-field, and multiple arrays with certain changes in their optics and illumination. This comprehensive review discusses the numerous applications and development of SIDs towards histopathological examination, detection of bacteria and viruses, food technology, and routine diagnosis. Smartphone-based devices are complemented with deep learning methods to further increase the efficiency of the devices. Graphical Abstract
Keywords	analytical chemistry ; education ; fluorescence ; food technology ; histopathology ; lighting
Language	English
Dates of publication	2021-04
Size	p. 2389-2406.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	NAL-AP-2-clean ; Review
ISSN	1618-2642
DOI	10.1007/s00216-021-03184-z
Database	NAL-Catalogue (AGRICOLA)

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Article: Investigation of structural and physico-chemical properties of rice starch with varied amylose content: A combined microscopy, spectroscopy, and thermal study

Govindaraju, Indira / Zhuo, Guan-Yu / Chakraborty, Ishita / Melanthota, Sindhoora Kaniyala / Mal, Sib Sankar / Sarmah, Bhaswati / Baruah, Vishwa Jyoti / Mahato, Krishna Kishore / Mazumder, Nirmal

Food hydrocolloids

2022 Volume 122, Issue -, Page(s) 107093

Language	English
Document type	Article
ZDB-ID	742742-6
ISSN	0268-005X
Database	Current Contents Nutrition, Environment, Agriculture

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Article: Investigation of structural and physico-chemical properties of rice starch with varied amylose content: A combined microscopy, spectroscopy, and thermal study

Govindaraju, Indira / Zhuo, Guan-Yu / Chakraborty, Ishita / Melanthota, Sindhoora Kaniyala / Mal, Sib Sankar / Sarmah, Bhaswati / Baruah, Vishwa Jyoti / Mahato, Krishna Kishore / Mazumder, Nirmal

Food hydrocolloids. 2022 Jan., v. 122

2022

Abstract: Starch from a given botanical source can vary considerably in terms of physicochemical properties in its native and hydrolyzed forms. The current study investigated the structural and functional characteristics of starch from ten indigenous rice ... ...

Abstract	Starch from a given botanical source can vary considerably in terms of physicochemical properties in its native and hydrolyzed forms. The current study investigated the structural and functional characteristics of starch from ten indigenous rice varieties endemic to Northeast India. In vitro enzymatic hydrolysis was used to reveal the dextrose equivalent profile of each type of starch. Gezep Sali and Betguti Sali respectively exhibited the highest and lowest starch hydrolysis. Among the ten rice varieties, amylose content varied between 7.50 and 28.58%. Optical and scanning electron microscopy (SEM) revealed the polyhedral shape of the native starch granules and deformation of the shape upon enzymatic hydrolysis. Second harmonic generation (SHG) microscopy and X-ray diffraction (XRD) analysis confirmed the presence of and variations in starch crystallinity. XRD revealed spectral peaks characteristic of A-type starch crystals in the native form. The elevated intensity of XRD peaks in hydrolyzed starch granules confirmed the occurrence of amylose hydrolysis rather than hydrolysis in amylopectin regions. Fourier transform infrared (FTIR) spectra revealed the common stretching and bending of bonds in all native starches; however, changes were observed in the fingerprint region (1080, 1000, 926 cm⁻¹) of hydrolyzed starch granules, which indicates the amylolysis of the amylose region and disturbances in the ordered arrangement in the crystalline part. Differential scanning calorimeter (DSC) endotherms revealed the highest and lowest gelatinization peak temperatures in Harfoni (78 °C) and Tulosi Sali (41 °C) rice cultivars, respectively. The findings in this study can help to optimize the usage of rice starch in food and non-food industries. Furthermore, understanding the control points of starch digestion and genetically tailoring rice grains with different digestibility could be beneficial for nutraceutical applications.
Keywords	Fourier transform infrared spectroscopy ; X-ray diffraction ; amylopectin ; amylose ; calorimeters ; crystal structure ; cultivars ; deformation ; dietary supplements ; digestibility ; digestion ; endothermy ; enzymatic hydrolysis ; gelatinization ; glucose ; hydrocolloids ; hydrolysis ; rice ; rice starch ; India
Language	English
Dates of publication	2022-01
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	742742-6
ISSN	1873-7137 ; 0268-005X
ISSN (online)	1873-7137
ISSN	0268-005X
DOI	10.1016/j.foodhyd.2021.107093
Database	NAL-Catalogue (AGRICOLA)

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