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Article ; Online: Letter in Response to the Article "Platelet-Rich Plasma Versus Platelet-Poor Plasma for Treating Facial Photoaging: A Double Blind Randomized Controlled Splitting Face Study" by Tsai and Cheng et al.

Tsai, Ya-Wen / Cheng, Chun-Yu / Huang, Yau-Li

2024

Language	English
Publishing date	2024-02-27
Publishing country	United States
Document type	Letter
ZDB-ID	532791-x
ISSN	1432-5241 ; 0364-216X
ISSN (online)	1432-5241
ISSN	0364-216X
DOI	10.1007/s00266-024-03934-1
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Zs.A 1296: Show issues

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Article ; Online: Osimertinib-induced urticarial vasculitis in a patient with lung cancer: A rare cutaneous toxicity.

Weng, Pei-Chun / Huang, Yau-Li / Cheng, Chun-Yu

European journal of cancer (Oxford, England : 1990)

2023 Volume 196, Page(s) 113432

MeSH term(s)	Humans ; Lung Neoplasms/drug therapy ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Acrylamides/adverse effects ; Aniline Compounds/adverse effects ; Skin Diseases ; Vasculitis/chemically induced ; Mutation ; Protein Kinase Inhibitors/adverse effects
Chemical Substances	osimertinib (3C06JJ0Z2O) ; Acrylamides ; Aniline Compounds ; Protein Kinase Inhibitors
Language	English
Publishing date	2023-11-11
Publishing country	England
Document type	Letter
ZDB-ID	82061-1
ISSN	1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
ISSN (online)	1879-0852
ISSN	0277-5379 ; 0959-8049 ; 0964-1947
DOI	10.1016/j.ejca.2023.113432
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Zs.A 456: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 583: Show issues

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Article: Comparative efficacy and safety between endoscopic submucosal dissection, surgery and definitive chemoradiotherapy in patients with cT1N0M0 esophageal cancer.

Luo, Shu-Ai / Sun, Yu-Ying / Zeng, Ya-Ting / Huang, Chun-Yu

World journal of gastrointestinal endoscopy

2024 Volume 16, Issue 2, Page(s) 72–82

Abstract: Background: Endoscopic submucosal dissection (ESD) and surgical resection are the standard of care for cT1N0M0 esophageal cancer (EC), whereas definitive chemoradiotherapy (d-CRT) is a treatment option. Nevertheless, the comparative efficiency and ... ...

Abstract	Background: Endoscopic submucosal dissection (ESD) and surgical resection are the standard of care for cT1N0M0 esophageal cancer (EC), whereas definitive chemoradiotherapy (d-CRT) is a treatment option. Nevertheless, the comparative efficiency and safety of ESD, surgery and d-CRT for cT1N0M0 EC remain unclear. Aim: To compare the efficiency and safety of ESD, surgery and d-CRT for cT1N0M0 EC. Methods: We retrospectively analyzed the hospitalized data of a total of 472 consecutive patients with cT1N0M0 EC treated at Sun Yat-sen University Cancer center between 2017-2019 and followed up until October 30th, 2022. We analyzed demographic, medical recorded, histopathologic characteristics, imaging and endoscopic, and follow-up data. The Kaplan-Meier method and Cox proportional hazards modeling were used to analyze the difference of survival outcome by treatments. Inverse probability of treatment weighting (IPTW) was used to minimize potential confounding factors. Results: We retrospectively analyzed patients who underwent ESD ( Conclusion: For cT1N0M0 EC, ESD had better long-term survival and lower hospitalization costs than those who underwent d-CRT and surgery, with a similar rate of severe complications occurring.
Language	English
Publishing date	2024-03-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573698-X
ISSN	1948-5190
ISSN	1948-5190
DOI	10.4253/wjge.v16.i2.72
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Article ; Online: Development of a Novel Diagram to Ameliorate the Recording, Documentation, and Presentation of Aesthetic Procedures.

Yen, Ju-Shao / Cheng, Chun-Yu / Huang, Yau-Li

Plastic and reconstructive surgery

2023 Volume 153, Issue 4, Page(s) 855e–857e

MeSH term(s)	Humans ; Surgery, Plastic ; Documentation/methods ; Esthetics
Language	English
Publishing date	2023-09-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000011089
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Uk I Zs.142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 293: Show issues

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Article ; Online: Effects of hospice-shared care on terminal cancer patients in Taiwan: A hospital-based observational study.

Huang, Hui-Wen / Liu, Chun-Yu / Tung, Tao-Hsin / Liu, Li-Ni

European journal of oncology nursing : the official journal of European Oncology Nursing Society

2024 Volume 69, Page(s) 102525

Abstract: Purpose: To assess how hospice-shared care (HSC) affected the likelihood of aggressive medical treatments and the life quality among terminal cancer patients.: Methods: In the first part, a cohort of 160 late-stage cancer patients who died in non- ... ...

Abstract	Purpose: To assess how hospice-shared care (HSC) affected the likelihood of aggressive medical treatments and the life quality among terminal cancer patients. Methods: In the first part, a cohort of 160 late-stage cancer patients who died in non-hospice wards were identified to review their charts in their last 22 days before death. In the second part, a total of 19 late-stage cancer patients with clear consciousness admitted to non-hospice wards were identified to investigate their quality of life for the final 2 weeks before death. Results: The utilization rate of HSC was 55.6%. Among these, the rate for late referral to HSC (≤7 days before death) was 43.8% and early referral (>3 months before death) was 5.6%. Compared to the non-HSC group, in the last few weeks of life, the HSC group underwent lower incidence of chemotherapy use (10.1% vs. 39.4%, p < .001), signed do-not-resuscitate orders (0% vs. 21.1%, p < .001), emergency room visits (13.5% vs. 40.8%, p < .001), intensive care unit admission or ventilator use (2.2% vs. 11.3%, p = .019), and endotracheal intubation (2.2% vs. 9.9%, p = .038). However, the quality of life did not appear to have obvious differences between the two groups (p > .05). Conclusion: In Taiwan, late HSC referral in terminal cancer patients is common. HSC is associated with a reduced likelihood of aggressive medical utilization. However, the effect of HSC in improving patients' quality of life in the last few weeks needs to be further evaluated.
MeSH term(s)	Humans ; Hospices ; Taiwan ; Quality of Life ; Hospice Care ; Neoplasms/therapy ; Terminal Care ; Retrospective Studies
Language	English
Publishing date	2024-02-05
Publishing country	Scotland
Document type	Observational Study ; Journal Article
ZDB-ID	2017117-1
ISSN	1532-2122 ; 1462-3889
ISSN (online)	1532-2122
ISSN	1462-3889
DOI	10.1016/j.ejon.2024.102525
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Zs.A 6219: Show issues

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Article ; Online: Nurse-led shared decision-making on complementary therapy use by patients with diabetes: An participatory action research.

Chang, Hsiao-Yun / Mao, Pei-Ling / Huang, Chun-Yu

Journal of clinical nursing

2023 Volume 32, Issue 17-18, Page(s) 6310–6321

Abstract: Aims: The aim of this study was to develop, implement and evaluate a nurse-led shared decision-making model of care for discussing the use of complementary and alternative medicine with diabetic patients and to explore to what extent the risk-benefit ... ...

Abstract	Aims: The aim of this study was to develop, implement and evaluate a nurse-led shared decision-making model of care for discussing the use of complementary and alternative medicine with diabetic patients and to explore to what extent the risk-benefit assessment of using complementary and alternative medicine can provide a framework for facilitating nurse-patient dialogue and strengthening patient involvement in their disease management. Design: Participatory action research with pre-post intervention. Methods: A two-run cycle of action and spirals from participatory action research was undertaken using a purposive sampling method to involve healthcare professionals and diabetic patients from September 2021 to June 2022. The nurse-led shared decision-making model of care was designed and implemented congruent with participatory action research principles. Quantitative measures were collected about patients' perceived involvement in shared decision-making and their understanding of the risks and benefits of using complementary and alternative medicine. Patients' outcomes of disease control (fasting plasma glucose and HbA1c) were also collected. Data were analysed using IBM SPSS software (version 28). Interviews were summarized using thematic analysis. An EQUATOR Network guideline for participatory action research supported the preparation of this paper. Results: Comparison of pre-post intervention outcomes showed that patients' scale scores on shared decision-making involvement and understanding of the risk-benefit of using complementary and alternative medicine improved significantly after implementing the model. Fasting plasma glucose improved only slightly after a 3-month follow-up. Conclusions: The care model strengthens patient involvement in their disease management and makes appropriate decisions about CAM use that should reduce potentially harmful side effects or interactions between CAM and conventional medicine. Implications for the profession and patient care: The shared decision-making model of care incorporates evidence-based CAM research into practice, facilitates the standardization of CAM management in diabetes, improves care options for patients and educates nurses about CAM use in managing diabetes. Patient or public contribution: No Patient or Public Contribution.
MeSH term(s)	Humans ; Blood Glucose ; Nurse's Role ; Diabetes Mellitus/therapy ; Complementary Therapies ; Health Services Research ; Decision Making
Chemical Substances	Blood Glucose
Language	English
Publishing date	2023-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1159483-4
ISSN	1365-2702 ; 0962-1067 ; 1752-9816
ISSN (online)	1365-2702
ISSN	0962-1067 ; 1752-9816
DOI	10.1111/jocn.16718
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Zs.A 3764: Show issues

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Article ; Online: The Modulation of Phospho-Extracellular Signal-Regulated Kinase and Phospho-Protein Kinase B Signaling Pathways plus Activity of Macrophage-Stimulating Protein Contribute to the Protective Effect of Stachydrine on Acetaminophen-Induced Liver Injury.

Liu, Fu-Chao / Yu, Huang-Ping / Lee, Hung-Chen / Chen, Chun-Yu / Liao, Chia-Chih

International journal of molecular sciences

2024 Volume 25, Issue 3

Abstract: Stachydrine, a prominent bioactive alkaloid derived from Leonurus heterophyllus, is a significant herb in traditional medicine. It has been noted for its anti-inflammatory and antioxidant characteristics. Consequently, we conducted a study of its ... ...

Abstract	Stachydrine, a prominent bioactive alkaloid derived from Leonurus heterophyllus, is a significant herb in traditional medicine. It has been noted for its anti-inflammatory and antioxidant characteristics. Consequently, we conducted a study of its hepatoprotective effect and the fundamental mechanisms involved in acetaminophen (APAP)-induced liver injury, utilizing a mouse model. Mice were intraperitoneally administered a hepatotoxic dose of APAP (300 mg/kg). Thirty minutes after APAP administration, mice were treated with different concentrations of stachydrine (0, 2.5, 5, and 10 mg/kg). Animals were sacrificed 16 h after APAP injection for serum and liver tissue assays. APAP overdose significantly elevated the serum alanine transferase levels, hepatic pro-inflammatory cytokines, malondialdehyde activity, phospho-extracellular signal-regulated kinase (ERK), phospho-protein kinase B (AKT), and macrophage-stimulating protein expression. Stachydrine treatment significantly decreased these parameters in mice with APAP-induced liver damage. Our results suggest that stachydrine may be a promising beneficial target in the prevention of APAP-induced liver damage through attenuation of the inflammatory response, inhibition of the ERK and AKT pathways, and expression of macrophage-stimulating proteins.
MeSH term(s)	Animals ; Mice ; Acetaminophen/toxicity ; Chemical and Drug Induced Liver Injury/drug therapy ; Chemical and Drug Induced Liver Injury/prevention & control ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury, Chronic/drug therapy ; Chemical and Drug Induced Liver Injury, Chronic/metabolism ; Extracellular Signal-Regulated MAP Kinases/drug effects ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Liver/metabolism ; Macrophages/metabolism ; Oxidative Stress ; Proline/analogs & derivatives ; Proto-Oncogene Proteins c-akt/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Macrophage Colony-Stimulating Factor/drug effects ; Macrophage Colony-Stimulating Factor/metabolism
Chemical Substances	Acetaminophen (362O9ITL9D) ; Extracellular Signal-Regulated MAP Kinases (EC 2.7.11.24) ; Proline (9DLQ4CIU6V) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; stachydrine (S1L688345C) ; Macrophage Colony-Stimulating Factor (81627-83-0)
Language	English
Publishing date	2024-01-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25031484
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Article ; Online: Transcutaneous lower eyelid blepharoplasty with micro-autologous fat transplantation harvested from orbital fat pads for lower eyelid aging treatment.

Cheng, Chun-Yu / Lin, Tsai-Ming / Chang, Shyue-Luen / Hu, Sindy / Huang, Yau-Li

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2024 Volume 93, Page(s) 111–113

Abstract: The aging process of lower eyelids results in lower eyelid wrinkles, tear troughs, and eye bags. Many therapies have been described for treatment of lower eyelid aging, and transcutaneous blepharoplasty is often used for treating cases with eyebags and ... ...

Abstract	The aging process of lower eyelids results in lower eyelid wrinkles, tear troughs, and eye bags. Many therapies have been described for treatment of lower eyelid aging, and transcutaneous blepharoplasty is often used for treating cases with eyebags and dermatochalasis. However, it may cause depression near the medial orbit resulting in a hollowed look. In the present study, we developed an innovative method transferring the herniated fatty tissue to volume loss area during the surgical procedure of transcutaneous lower eyelid blepharoplasty by means of micro-autologous fat transplantation harvested from resected orbital fat pads. Besides, we also analyze it efficacy and safety compared with traditional methods of transcutaneous lower eyelid blepharoplasty. We reviewed the records of the patients who underwent transcutaneous lower eyelid blepharoplasty with and without micro-autologous fat transplantation, for lower eyelid aging improvement. We used global aesthetic improvement scale, Hirmand's classification system, and Wrinkle Severity Rating Scale to evaluate the cosmetic outcome at 1 week, 1 month, and 3 months after operation by two independent investigators. We found patients received transcutaneous lower eyelid blepharoplasty with autologous fat graft had significantly higher global aesthetic improvement scale and Wrinkle Severity Rating Scale improvement than those underwent transcutaneous lower eyelid blepharoplasty only in each evaluation timepoints. There was no significant difference of adverse effects between both surgical methods. The present study demonstrated the efficacy and safety of the lower eyelid blepharoplasty with micro-autologous fat transplantation harvesting from resected orbital fat pads.
Language	English
Publishing date	2024-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2024.04.050
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Article ; Online: Pinch and stretch test to assess and categorize the severity of acne rolling scars.

Hung, Yi-Teng / Cheng, Chun-Yu / Huang, Yau-Li

Journal of the American Academy of Dermatology

2022 Volume 87, Issue 5, Page(s) e133–e134

MeSH term(s)	Acne Vulgaris/complications ; Acne Vulgaris/diagnosis ; Atrophy ; Cicatrix/diagnosis ; Cicatrix/etiology ; Cicatrix/pathology ; Humans ; Treatment Outcome
Language	English
Publishing date	2022-08-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2022.08.022
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Zs.A 1540: Show issues

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Article ; Online: Finger Compression Technique with an OK Gesture on the Bilateral Emerging Points of the Ophthalmic Artery: A Simple Three-Step Method with Dual Real-Time Imaging to Reduce the Risk of Filler-Associated Blindness.

Hung, Yi-Teng / Cheng, Chun-Yu / Huang, Yau-Li

Plastic and reconstructive surgery

2022 Volume 151, Issue 2, Page(s) 351e–353e

MeSH term(s)	Humans ; Ophthalmic Artery/diagnostic imaging ; Gestures ; Blindness/etiology ; Blindness/prevention & control ; Dermal Fillers/adverse effects ; Cosmetic Techniques/adverse effects
Chemical Substances	Dermal Fillers
Language	English
Publishing date	2022-11-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000009876
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Zs.MO 293: Show issues

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