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  1. Book ; Online: Have actions taken to control fall armyworm reduced the economic cost experienced in Ghana?

    Williams, Frances / Murphy, Sean T. / Beseh, Patrick / Lamontagne-Godwin, Julien

    (Study brief / CABI : Impact ; 31)

    2019  

    Author's details F. Williams, S.T. Murphy, P. Beseh, J. Lamontagne-Godwin
    Series title Study brief / CABI : Impact ; 31
    Study brief
    Study brief / CABI
    Collection Study brief
    Study brief / CABI
    Language English
    Size 1 Online-Ressource (10 Seiten), Diagramm, Karte
    Publisher CABI
    Publishing place Wallingford, Oxfordshire
    Publishing country Great Britain
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020647663
    DOI 10.1079/CABICOMM-62-8108
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: INvestigation of the impact of a Pharmacist in a Hospital At Home Care Team (IN PHACT).

    Patrick, Morgan E / Harder, Curtis K / Spina, Sean P

    Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

    2023  Volume 156, Issue 6, Page(s) 324–330

    Abstract: Background: In November 2020, Island Health, with the support of the British Columbia Ministry of Health, introduced the Hospital at Home (HaH) care model at Victoria General Hospital in Victoria, British Columbia. Given the acuity of the patients ... ...

    Abstract Background: In November 2020, Island Health, with the support of the British Columbia Ministry of Health, introduced the Hospital at Home (HaH) care model at Victoria General Hospital in Victoria, British Columbia. Given the acuity of the patients anticipated to receive care through this model, questions arose regarding how the delivery of clinical pharmacy services on which inpatients rely on could be included. With limited supporting evidence for the inclusion of a clinical pharmacist, Island Health launched the HaH program with 2 clinical pharmacists who provide services 7 days a week during daytime hours. The aim of this study is to assess the impact of the HaH pharmacist on patient care, from the perspective of the pharmacists serving in this role, patients, caregivers and program stakeholders.
    Methods: This prospective, observational mixed-methods study was conducted from December 2021 to March 2022. Data collection involved the HaH pharmacist documenting daily clinical activities and resolving drug therapy problems, patients and caregivers completing a 4-question postdischarge phone survey and program stakeholders completing a 9-question online survey and an optional 7-question interview.
    Results and interpretation: It was found that one of the most significant roles the pharmacist plays is in identifying indications for medication therapy and making recommendations to initiate therapy where there is an absence. There was high congruence between patient, caregiver and stakeholder perceptions that the HaH pharmacist positively affects patient care within the Island Health model.
    Conclusion: This study provides support for the integration of a dedicated clinical pharmacist in the HaH care model.
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2200008-2
    ISSN 1913-701X ; 1715-1635
    ISSN (online) 1913-701X
    ISSN 1715-1635
    DOI 10.1177/17151635231200233
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    Zs.B 932: Show issues Location:
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  3. Article ; Online: The enigma of Sir William Robert Wills Wilde (1815-1876).

    Boland, Patrick / Hughes, Sean P

    Journal of medical biography

    2021  Volume 31, Issue 3, Page(s) 160–167

    Abstract: William Wilde, father of Oscar Wilde, made a significant contribution to ophthalmology and otology. Qualified as a surgeon. educated in statistics and showing sympathy for the Irish population, Wilde was appointed a Commissioner for the 1851 Census, ... ...

    Abstract William Wilde, father of Oscar Wilde, made a significant contribution to ophthalmology and otology. Qualified as a surgeon. educated in statistics and showing sympathy for the Irish population, Wilde was appointed a Commissioner for the 1851 Census, which covered the time of the Irish Famine (1845-1852). Wilde, steeped in Irish mythology, used his knowledge to develop a close rapport with the Irish peasantry. However, his life was a paradox; he supported the British Government's approach to the Famine and at the same time he showed humanity to the Irish peasantry. In his personal life he was implicated in an abortive libel case involving a young female patient who had accused him of rape. Wilde lived as though he had two separate lives
    MeSH term(s) Humans ; Male ; Female ; History, 19th Century ; Living Wills ; Humanities ; Ophthalmology/history ; Otolaryngology/history
    Language English
    Publishing date 2021-10-21
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 1159267-9
    ISSN 1758-1087 ; 0967-7720
    ISSN (online) 1758-1087
    ISSN 0967-7720
    DOI 10.1177/09677720211046588
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  4. Article: Hospital at home: The role for clinical pharmacy in an innovative acute care model in British Columbia.

    Patrick, Morgan E / Harder, Curtis K / Spina, Sean P

    Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

    2021  Volume 155, Issue 1, Page(s) 18–20

    Language English
    Publishing date 2021-09-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2200008-2
    ISSN 1913-701X ; 1715-1635
    ISSN (online) 1913-701X
    ISSN 1715-1635
    DOI 10.1177/17151635211045951
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  5. Article ; Online: Pilot study to develop a pre-operative "Cardiothoracic Clinical Handover Tool" and its effect on handover quality.

    Kehoe, John David / Higgins, Patrick / Barrett, Sean / Hinchion, John

    Irish journal of medical science

    2023  

    Abstract: ... improved from a score of 63.75% to 88.57% (p = < 0.001). This prolonged handover duration from a mean of 72 ... 1 to 102.4 seconds per case (p = 0.003). Interruptions occurred in 27.5% of pre- and 25% of post ... intervention groups (114.6 vs 77.7 seconds, p = 0.012) and poorer quality handovers in the pre-intervention ...

    Abstract Background: Clinical handover is an essential step in the surgical patient's hospital journey, but one that is not without risk. Within cardiothoracic surgery, endeavours to protocolise post-operative handover from cardiac theatre to cardiac intensive care units have resulted in enhanced patient safety, but little to no effort has focused on the pre-operative setting and the dissemination of information throughout the surgical team.
    Methods: We designed a pre-post study examining the quality of pre-operative cardiothoracic patient handovers before and after the introduction of an intra-departmentally designed "Cardiothoracic Clinical Handover Tool" based on the Royal College of Surgeons of England's guidelines for "Safe Handover".
    Results: Forty clinical handovers were assessed in each arm of the study. Handover quality improved from a score of 63.75% to 88.57% (p = < 0.001). This prolonged handover duration from a mean of 72.1 to 102.4 seconds per case (p = 0.003). Interruptions occurred in 27.5% of pre- and 25% of post-intervention handovers. Interruptions resulted in increased handover duration in both pre- and post-intervention groups (114.6 vs 77.7 seconds, p = 0.012) and poorer quality handovers in the pre-intervention group (51.28% vs 68.42%, p = 0.03) but failed to impact handover quality in the post-intervention group (88.57% vs 88.57%, p = 1).
    Conclusions: Clinical handover tools have the potential to enhance the quality of pre-operative handover and protect against poor handover practices such as interruptions, safe-guarding patient welfare. We provide the first cardiothoracic specific pre-operative handover tool based on the RCSE guidelines.
    Language English
    Publishing date 2023-12-08
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-023-03585-2
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    Zs.B 323: Show issues Location:
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  6. Article ; Online: QTL mapping of resistance to Pseudoperonospora cubensis clade 2, mating type A1, in Cucumis melo and dual-clade marker development.

    Toporek, Sean M / Branham, Sandra E / Keinath, Anthony P / Wechter, W Patrick

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

    2023  Volume 136, Issue 4, Page(s) 91

    Abstract: ... melon). A recombinant inbred line population (N = 169) was screened against an isolate of P. cubensis ... QTLs (qPcub-8.2 and qPcub-10.1) previously identified for resistance to P. cubensis Clade 1/mating type ...

    Abstract Key message: This is the first identification of QTLs underlying resistance in Cucumis melo to an isolate of Pseudoperonospora cubensis identified as Clade 2/mating type A1. Pseudoperonospora cubensis, causal organism of cucurbit downy mildew (CDM), causes severe necrosis and defoliation on Cucumis melo (melon). A recombinant inbred line population (N = 169) was screened against an isolate of P. cubensis (Clade 2/mating type A1) in replicated greenhouse and growth chamber experiments. SNPs (n = 5633 bins) identified in the RIL population were used for quantitative trait loci (QTL) mapping. A single major QTL on chromosome 10 (qPcub-10.3-10.4) was consistently associated with resistance across all experiments, while a second major QTL on chromosome 8 (qPcub-8.3) was identified only in greenhouse experiments. These two major QTLs were identified on the same chromosomes (8 and 10) but in different locations as two major QTLs (qPcub-8.2 and qPcub-10.1) previously identified for resistance to P. cubensis Clade 1/mating type A2. Kompetitive allele-specific PCR (KASP) markers were developed for these four major QTLs and validated in the RIL population through QTL mapping. These markers will provide melon breeders a high-throughput genotyping toolkit for development of melon cultivars with broad tolerance to CDM.
    MeSH term(s) Quantitative Trait Loci ; Cucumis melo/genetics ; Plant Diseases/genetics ; Oomycetes ; Peronospora ; Cucurbitaceae/genetics
    Language English
    Publishing date 2023-04-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2170-2
    ISSN 1432-2242 ; 0040-5752
    ISSN (online) 1432-2242
    ISSN 0040-5752
    DOI 10.1007/s00122-023-04333-x
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    Zs.A 1692: Show issues Location:
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  7. Article ; Online: A Cost Analysis of Surgical Approach in Total Hip Arthroplasty.

    Cochrane, Niall H / Wixted, Colleen / Kim, Billy / Kelly, Patrick J / Bolognesi, Michael P / Holst, David / Wellman, Samuel / Ryan, Sean P

    Orthopedics

    2024  , Page(s) 1–6

    Abstract: ... encounter costs for two surgical approaches to THA-posterior (P) and direct anterior (DA).: Materials and ... methods: A total of 233 THAs (134 P and 99 DA) performed by two fellowship-trained arthroplasty surgeons ... Results: There were differences in age (67 years for DA and 63 years for P; : Conclusion: The DA ...

    Abstract Background: With pressures to decrease the financial burden of total hip arthroplasty (THA), it is imperative to understand the cost drivers of this procedure. This study evaluated operative and total encounter costs for two surgical approaches to THA-posterior (P) and direct anterior (DA).
    Materials and methods: A total of 233 THAs (134 P and 99 DA) performed by two fellowship-trained arthroplasty surgeons from 2017 to 2022 were reviewed. Demographics, comorbidities, mobility status, operative time, length of stay, implants used, discharge location, and complications until final follow-up were recorded. Total encounter cost was collected and itemized. Multivariable regression analyses evaluated predictors of cost.
    Results: There were differences in age (67 years for DA and 63 years for P;
    Conclusion: The DA cohort had improved measures of health; however, this approach was associated with a higher operative cost and was predictive of increased encounter cost despite a shorter length of stay. [
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424447-3
    ISSN 1938-2367 ; 0147-7447
    ISSN (online) 1938-2367
    ISSN 0147-7447
    DOI 10.3928/01477447-20240304-03
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    Zs.A 1487: Show issues Location:
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  8. Article ; Online: University of Ottawa's Department of Emergency Medicine simulation boot camp: a descriptive review.

    Patrick, Sean P / Mastoras, George / Krywenky, Ashley

    BMJ simulation & technology enhanced learning

    2020  Volume 6, Issue 3, Page(s) 184–185

    Language English
    Publishing date 2020-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2799014-X
    ISSN 2056-6697 ; 2056-6697
    ISSN (online) 2056-6697
    ISSN 2056-6697
    DOI 10.1136/bmjstel-2019-000467
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  9. Article ; Online: ASO Visual Abstract: Outcomes of Neoadjuvant Chemotherapy for Invasive Intraductal Papillary Mucinous Neoplasm Compared with De Novo Pancreatic Adenocarcinoma.

    Fogliati, Alessandro / Zironda, Andrea / Fiorentini, Guido / Adjei, Stella / Amro, Abdelrahman / Starlinger, Patrick P / Grotz, Travis E / Warner, Susanne G / Smoot, Rory L / Thiels, Cornelius A / Kendrick, Michael L / Cleary, Sean P / Truty, Mark J

    Annals of surgical oncology

    2024  

    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-15016-2
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    Zs.A 4042: Show issues Location:
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  10. Article ; Online: Effects of total sleep deprivation on sensorimotor gating in humans.

    Vizeli, Patrick / Cuccurazzu, Bruna / Drummond, Sean P A / Acheson, Dean T / Risbrough, Victoria B

    Behavioural brain research

    2023  Volume 449, Page(s) 114487

    Abstract: Sensorimotor gating is a measure of pre-attentional information processing and can be measured by prepulse inhibition (PPI) of the startle reflex. Sleep deprivation has been shown to disrupt PPI in animals and humans, and has been proposed as an early ... ...

    Abstract Sensorimotor gating is a measure of pre-attentional information processing and can be measured by prepulse inhibition (PPI) of the startle reflex. Sleep deprivation has been shown to disrupt PPI in animals and humans, and has been proposed as an early phase 2 model to probe antipsychotic efficacy in heathy humans. To further investigate the reliability and efficacy of sleep deprivation to produce PPI deficits we tested the effects of total sleep deprivation (TSD) on PPI in healthy controls in a highly controlled sleep laboratory environment. Participants spent 4 days and nights in a controlled laboratory environment with their sleep monitored with polysomnography. Participants were randomly assigned to either normal sleep on all 4 nights (N = 17) or 36 h of TSD on the 3rd or 4th night (N = 40). Participants were assessed for sleepiness using the Karolinska Sleepiness Scale (KSS) and underwent a daily PPI task (interstimlulus intervals 30-2000 ms) in the evening. Both within-subject effects (TSD vs. normal sleep in TSD group alone) and between-subject effects (TSD vs. no TSD group) of TSD on PPI were assessed. TSD increased subjective sleepiness measured with the KSS, but did not significantly alter overall startle, habituation or PPI. Sleep measures including duration, rapid eye movement and slow wave sleep duration were also not associated with PPI performance. The current results show that human sensorimotor gating may not be reliably sensitive to sleep deprivation. Further research is required for TSD to be considered a dependable model of PPI disruption for drug discovery in humans.
    MeSH term(s) Animals ; Humans ; Sleep Deprivation ; Sleepiness ; Reproducibility of Results ; Attention/physiology ; Sleep ; Sensory Gating/physiology ; Reflex, Startle/physiology
    Language English
    Publishing date 2023-05-09
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 449927-x
    ISSN 1872-7549 ; 0166-4328
    ISSN (online) 1872-7549
    ISSN 0166-4328
    DOI 10.1016/j.bbr.2023.114487
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