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  1. Article ; Online: Rare liver diseases in Egypt: Clinical and epidemiological characterization.

    Abdelhamed, Walaa / El-Kassas, Mohamed

    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

    2024  

    Abstract: Illnesses that afflict a tiny number of individuals are referred to as rare diseases (RDs), sometimes called orphan diseases. The local healthcare systems are constantly under financial, psychological, and medical strain due to low incidence rates, ... ...

    Abstract Illnesses that afflict a tiny number of individuals are referred to as rare diseases (RDs), sometimes called orphan diseases. The local healthcare systems are constantly under financial, psychological, and medical strain due to low incidence rates, unusual presentations, flawed diagnostic standards, and a lack of treatment alternatives for these RDs. The effective management of the once widely spread viral hepatitis B and C has altered the spectrum of liver diseases in Egypt during the last several years. The detection of uncommon disorders such as autoimmune, cholestatic, and hereditary liver diseases has also been made easier by the increasing knowledge and greater accessibility of specific laboratory testing. Finally, despite Egypt's large population, there are more uncommon liver disorders than previously thought. This review article discusses the clinical and epidemiological characteristics of a few uncommon liver disorders and the information currently accessible concerning these illnesses in Egypt.
    Language English
    Publishing date 2024-01-15
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 2502114-X
    ISSN 2090-2387 ; 1687-1979
    ISSN (online) 2090-2387
    ISSN 1687-1979
    DOI 10.1016/j.ajg.2023.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hepatocellular Carcinoma in Africa: Challenges and Opportunities.

    El-Kassas, Mohamed / Elbadry, Mohamed

    Frontiers in medicine

    2022  Volume 9, Page(s) 899420

    Language English
    Publishing date 2022-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.899420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Steatotic liver disease as a new nomenclature for NAFLD from the perspectives of the MENA region: One size fits all this time.

    El-Kassas, Mohamed / Alswat, Khalid

    Journal of hepatology

    2023  Volume 80, Issue 2, Page(s) e66–e68

    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease ; Terminology as Topic
    Language English
    Publishing date 2023-08-22
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2023.08.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2027: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Artificial Intelligence in endoscopy: A future poll.

    Elshaarawy, Omar / Alboraie, Mohamed / El-Kassas, Mohamed

    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

    2024  Volume 25, Issue 1, Page(s) 13–17

    Abstract: Artificial Intelligence [AI] has been a trendy topic in recent years, with many developed medical applications. In gastrointestinal endoscopy, AI systems include computer-assisted detection [CADe] for lesion detection as bleedings and polyps and computer- ...

    Abstract Artificial Intelligence [AI] has been a trendy topic in recent years, with many developed medical applications. In gastrointestinal endoscopy, AI systems include computer-assisted detection [CADe] for lesion detection as bleedings and polyps and computer-assisted diagnosis [CADx] for optical biopsy and lesion characterization. The technology behind these systems is based on a computer algorithm that is trained for a specific function. This function could be to recognize or characterize target lesions such as colonic polyps. Moreover, AI systems can offer technical assistance to improve endoscopic performance as scope insertion guidance. Currently, we believe that such technologies still lack legal and regulatory validations as a large sector of doctors and patients have concerns. However, there is no doubt that these technologies will bring significant improvement in the endoscopic management of patients as well as save money and time.
    MeSH term(s) Humans ; Artificial Intelligence ; Endoscopy, Gastrointestinal ; Polyps
    Language English
    Publishing date 2024-01-13
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 2502114-X
    ISSN 2090-2387 ; 1687-1979
    ISSN (online) 2090-2387
    ISSN 1687-1979
    DOI 10.1016/j.ajg.2023.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Shedding lights on diagnostic challenges in Wilson's disease: The positive impact of introducing steatotic liver disease new nomenclature umbrella.

    Hassan, Marwa Khalaf / Alswat, Khalid / El-Kassas, Mohamed

    Liver international : official journal of the International Association for the Study of the Liver

    2024  Volume 44, Issue 5, Page(s) 1267–1268

    MeSH term(s) Humans ; Hepatolenticular Degeneration/diagnosis ; Liver ; Copper ; Fatty Liver
    Chemical Substances Copper (789U1901C5)
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Letter
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.15868
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Anesthesia in patients with chronic liver disease: An updated review.

    Bedewy, Ahmed / El-Kassas, Mohamed

    Clinics and research in hepatology and gastroenterology

    2023  Volume 47, Issue 8, Page(s) 102205

    Abstract: Anesthesia in chronic liver disease patients can be challenging because of the medications given or interventions performed and their effects on liver physiology. Also, the effects of liver disease on coagulation and metabolism should be considered ... ...

    Abstract Anesthesia in chronic liver disease patients can be challenging because of the medications given or interventions performed and their effects on liver physiology. Also, the effects of liver disease on coagulation and metabolism should be considered carefully. This review focuses on anesthesia in patients with different chronic liver disease stages. A literature search was performed for Scopus and PubMed databases for articles discussing different types of anesthesia in patients with chronic liver disease, their safety, usage, and risks. The choice of anesthesia is of crucial importance. Regional anesthesia, especially neuroaxial anesthesia, may benefit some patients with liver disease, but coagulopathy should be considered. Regional anesthesia provides optimum intraoperative relaxation and analgesia that extends to the postoperative period while avoiding the side effects of intravenous anesthetics and opioids. Pharmacodynamics and pharmacokinetics of anesthetic medications must guard against complications related to overdose or decreased metabolism. The choice of anesthesia in chronic liver disease patients is crucial and could be tailored according to the degree of liver compensation and the magnitude of the surgical procedure.
    Language English
    Publishing date 2023-09-05
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2023.102205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Diagnosis, treatment protocols, and outcomes of liver transplant recipients infected with COVID-19.

    Hashem, Mai / El-Kassas, Mohamed

    World journal of clinical cases

    2023  Volume 11, Issue 10, Page(s) 2140–2159

    Abstract: Several cases of fatal pneumonia during November 2019 were linked initially to severe acute respiratory syndrome coronavirus 2, which the World Health Organization later designated as coronavirus disease 2019 (COVID-19). The World Health Organization ... ...

    Abstract Several cases of fatal pneumonia during November 2019 were linked initially to severe acute respiratory syndrome coronavirus 2, which the World Health Organization later designated as coronavirus disease 2019 (COVID-19). The World Health Organization declared COVID-19 as a pandemic on March 11, 2020. In the general population, COVID-19 severity can range from asymptomatic/mild symptoms to seriously ill. Its mortality rate could be as high as 49%. The Centers for Disease Control and Prevention have acknowledged that people with specific underlying medical conditions, among those who need immunosuppression after solid organ transplantation (SOT), are at an increased risk of developing severe illness from COVID-19. Liver transplantation is the second most prevalent SOT globally. Due to their immunosuppressed state, liver transplant (LT) recipients are more susceptible to serious infections. Therefore, comorbidities and prolonged immunosuppression among SOT recipients enhance the likelihood of severe COVID-19. It is crucial to comprehend the clinical picture, immunosuppressive management, prognosis, and prophylaxis of COVID-19 infection because it may pose a danger to transplant recipients. This review described the clinical and laboratory findings of COVID-19 in LT recipients and the risk factors for severe disease in this population group. In the following sections, we discussed current COVID-19 therapy choices, reviewed standard practice in modifying immunosuppressant regimens, and outlined the safety and efficacy of currently licensed drugs for inpatient and outpatient management. Additionally, we explored the clinical outcomes of COVID-19 in LT recipients and mentioned the efficacy and safety of vaccination use.
    Language English
    Publishing date 2023-04-12
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i10.2140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tailored Model of Care for Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease.

    El-Kassas, Mohamed / Awad, Abeer / Elbadry, Mohamed / Arab, Juan Pablo

    Seminars in liver disease

    2024  Volume 44, Issue 1, Page(s) 54–68

    Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD), is increasing globally, creating a growing public health concern. However, this disease is often not diagnosed, and accurate ... ...

    Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD), is increasing globally, creating a growing public health concern. However, this disease is often not diagnosed, and accurate data on its epidemiology are limited in many geographical regions, making it challenging to provide proper care and implement effective national plans. To combat the increasing disease burden, screening and diagnosis must reach a significant number of high-risk subjects. Addressing MASLD as a health care challenge requires a multidisciplinary approach involving prevention, diagnosis, treatment, and care, with collaboration between multiple stakeholders in the health care system. This approach must be guided by national and global strategies, to be combined with efficient models of care developed through a bottom-up process. This review article highlights the pillars of the MASLD model of care (MoC), including screening, risk stratification, and establishing a clinical care pathway for management, in addition to discussing the impact of nomenclature change on the proposed MoC.
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/complications ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/epidemiology
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 603177-8
    ISSN 1098-8971 ; 0272-8087
    ISSN (online) 1098-8971
    ISSN 0272-8087
    DOI 10.1055/a-2253-9181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1752: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Barrett's esophagus in a patient with bulimia nervosa: A case report.

    Gouda, Ahmed / El-Kassas, Mohamed

    World journal of clinical cases

    2022  Volume 10, Issue 17, Page(s) 5841–5845

    Abstract: Background: Barrett's esophagus is a known complication of long-standing gastroesophageal reflux disease, and it is a potential risk factor of developing esophageal adenocarcinoma.: Case summary: Here, we present a case of a 47-year-old male patient ... ...

    Abstract Background: Barrett's esophagus is a known complication of long-standing gastroesophageal reflux disease, and it is a potential risk factor of developing esophageal adenocarcinoma.
    Case summary: Here, we present a case of a 47-year-old male patient referred to the gastroenterology clinic for upper endoscopy because he has a long-standing history of heartburn and vomiting after meals. On examination, he had characteristic findings of self-induced vomiting as abrasions and callosities on the dorsum of the right hand and dental erosions. A detailed history revealed that he had 17 years of binge eating with self-induced vomiting. His upper endoscopy showed gastroesophageal reflux grade D with salmon-red mucosal projections, and the biopsy revealed intestinal mucosal metaplasia.
    Conclusion: This case emphasized the importance of considering upper endoscopy screening for Barrett's esophagus in patients with eating disorders, especially those with self-induced vomiting, as in bulimia nervosa.
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v10.i17.5841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Fibrolamellar hepatocellular carcinoma: A rare but unpleasant event.

    Abdelhamed, Walaa / El-Kassas, Mohamed

    World journal of gastrointestinal oncology

    2022  Volume 14, Issue 6, Page(s) 1103–1114

    Abstract: Fibrolamellar carcinoma (FLC) is a rare variant of hepatocellular carcinoma (HCC), comprising 1%-9% of all HCCs. FLC is a poorly understood malignancy, which seems to be more prevalent in young patients with no underlying liver diseases. The term " ... ...

    Abstract Fibrolamellar carcinoma (FLC) is a rare variant of hepatocellular carcinoma (HCC), comprising 1%-9% of all HCCs. FLC is a poorly understood malignancy, which seems to be more prevalent in young patients with no underlying liver diseases. The term "fibrolamellar" is derived from thick fibrous collagen bands surrounding the tumor cells. Unlike HCC, cirrhosis and viral hepatitis infection are not predisposing to FLC, and it is not associated with elevations in serum alpha-fetoprotein. FLC patients often present with vague abdominal pain, nausea, malaise, and weight loss. Most cases present are at an advanced stage at the time of initial diagnosis. However, curative treatment options can still be offered to up to 70% of patients. Surgery (resection/liver transplantation) is the mainstay of treatment and the only potentially curative option. FLCs have been less chemo-responsive than the conventional HCC, however, in advanced cases, multimodality treatments can be effective. Recent advances in molecular studies of FLC have found a unique DNAJB1-PRKACA fusion transcript in most of the cases studied. The review aims to describe clinical characteristics, diagnostic methods, and therapeutic modalities for this rare tumor to raise awareness among clinicians and surgeons.
    Language English
    Publishing date 2022-06-24
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573696-6
    ISSN 1948-5204
    ISSN 1948-5204
    DOI 10.4251/wjgo.v14.i6.1103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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