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  1. Book: ESCMID guidelines for the management of the infection control measures to reduce transmission of mulidrug resistant Gram negative bacteria in hospitalized patients

    Canton, Rafael

    (Clinical microbiology and infection ; 20, Suppl. 1)

    2014  

    Title variant Guidelines for the management of the infection control measures to reduce transmission of mulidrug resistant Gram negative bacteria in hospitalized patients ; ESCMID guidelines for the management of the infection control measures to reduce transmission of mulidrug-resistant Gram-negative bacteria in hospitalized patients
    Institution European Society of Clinical Microbiology and Infectious Diseases
    Author's details guest ed. Rafael Canton
    Series title Clinical microbiology and infection ; 20, Suppl. 1
    Collection
    Language English
    Size 55 S.
    Publisher Wiley-Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018145443
    Database Catalogue ZB MED Medicine, Health

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    Zs A 4541 -20,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: New Variants in SARS-CoV-2: What are we Learning from the Omicron Variant?

    Galán, Juan Carlos / Cantón, Rafael

    Archivos de bronconeumologia

    2022  Volume 58 Suppl 1, Page(s) 3–5

    MeSH term(s) COVID-19 ; Humans ; Mutation ; SARS-CoV-2/genetics
    Language Spanish
    Publishing date 2022-04-15
    Publishing country Spain
    Document type Editorial
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2022.03.005
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  3. Article ; Online: Surveillance studies on antimicrobial susceptibility, from international to local studies.

    Cantón, Rafael / Morosini, María Isabel

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2020  Volume 38, Issue 4, Page(s) 147–149

    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Drug Resistance, Bacterial ; Humans ; Infections/drug therapy ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; Spain
    Chemical Substances Anti-Bacterial Agents
    Language Spanish
    Publishing date 2020-03-14
    Document type Editorial ; Comment
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2020.02.012
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  4. Article ; Online: Relevance of the Consensus Principles for Appropriate Antibiotic Prescribing in 2022.

    Cantón, Rafael / Akova, Murat / Langfeld, Karen / Torumkuney, Didem

    The Journal of antimicrobial chemotherapy

    2022  Volume 77, Issue Suppl_1, Page(s) i2–i9

    Abstract: Background: In the late 1990s, as a response to rising antimicrobial resistance (AMR), an independent multinational, interdisciplinary group was formed specifically targeting primary care antibiotic prescribing for community-acquired respiratory tract ... ...

    Abstract Background: In the late 1990s, as a response to rising antimicrobial resistance (AMR), an independent multinational, interdisciplinary group was formed specifically targeting primary care antibiotic prescribing for community-acquired respiratory tract infections (CA-RTIs). The group comprised senior clinicians from Canada, Israel, Spain, Sweden, UK and USA. The group's objectives were to provide recommendations for antibiotic stewardship in the community because, whilst it was widely accepted that inappropriate antibiotic use was contributing to AMR, it remained difficult to change prescribing behaviour. The group aimed to identify principles underlying appropriate antibiotic prescribing and guideline formulation to reduce morbidity from CA-RTIs, limit therapeutic failure and, importantly, curb AMR emergence. The group published a report in 2002, which has become known as the Consensus Principles.
    Objectives: (i) To consider the relevance of the Consensus Principles in 2022 by reviewing current global approaches to rising AMR. A wide range of factors, such as antibiotic overuse, most recently seen in COVID-19 patients, are still driving rising AMR even though there has been a high-level international response to the AMR threat; and (ii) as an introduction to this Supplement, which reports the findings of analyses of how AMR is being addressed in nine disparate countries (Brazil, India, Kuwait, Mexico, Pakistan, Russia, Saudi Arabia, Türkiye and Vietnam). Understanding how these initiatives are being pursued in different countries helps identify areas where more information is needed.
    Conclusions: Adherence to the Consensus Principles remains as important now as it was in 2002. Achieving appropriate antibiotic prescribing is a vital objective in order that the right patient receives the right antibiotics at the right time to ensure optimal clinical outcomes while at the same time helping to limit further increases in AMR.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship ; COVID-19 ; Community-Acquired Infections/drug therapy ; Consensus ; Humans ; Inappropriate Prescribing ; Respiratory Tract Infections/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-09-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkac211
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  5. Article ; Online: Evolution of ceftazidime-avibactam and cefiderocol resistance in ST131-H30R1-

    Castillo-Polo, Juan Antonio / Hernández-García, Marta / Maruri-Aransolo, Ainhize / de la Vega, Carmen / Ruiz-Garbajosa, Patricia / Cantón, Rafael

    Microbiology spectrum

    2024  Volume 12, Issue 4, Page(s) e0277623

    Abstract: Ceftazidime-avibactam and cefiderocol represent two of the few alternatives for infections by KPC-producing Enterobacterales. We reported the emergence of resistance to both ceftazidime-avibactam and cefiderocol in a KPC-producing ST131- ...

    Abstract Ceftazidime-avibactam and cefiderocol represent two of the few alternatives for infections by KPC-producing Enterobacterales. We reported the emergence of resistance to both ceftazidime-avibactam and cefiderocol in a KPC-producing ST131-
    MeSH term(s) Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Cefiderocol ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Spectroscopy, Fourier Transform Infrared ; beta-Lactamases/genetics ; beta-Lactamases/metabolism ; Carbapenems ; Microbial Sensitivity Tests ; Klebsiella pneumoniae/genetics ; Bacterial Proteins/genetics ; Ceftazidime ; Drug Combinations ; Azabicyclo Compounds
    Chemical Substances avibactam, ceftazidime drug combination ; Anti-Bacterial Agents ; Cefiderocol (SZ34OMG6E8) ; beta-Lactamases (EC 3.5.2.6) ; Carbapenems ; Bacterial Proteins ; Ceftazidime (9M416Z9QNR) ; Drug Combinations ; Azabicyclo Compounds
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.02776-23
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  6. Article ; Online: Treatment of carbapenem-resistant

    Canton, Rafael / Doi, Yohei / Simner, Patricia J

    Expert review of anti-infective therapy

    2022  Volume 20, Issue 8, Page(s) 1077–1094

    Abstract: Introduction: Carbapenem-resistant (CR) : Areas covered: This article reviews the mechanisms of : Expert opinion: Cefiderocol is active against most ... ...

    Abstract Introduction: Carbapenem-resistant (CR)
    Areas covered: This article reviews the mechanisms of
    Expert opinion: Cefiderocol is active against most known
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Carbapenems/pharmacology ; Carbapenems/therapeutic use ; Cephalosporins/pharmacology ; Cephalosporins/therapeutic use ; Humans ; Microbial Sensitivity Tests ; Pseudomonas Infections/drug therapy ; Pseudomonas aeruginosa ; beta-Lactamase Inhibitors/therapeutic use ; Cefiderocol
    Chemical Substances Anti-Bacterial Agents ; Carbapenems ; Cephalosporins ; beta-Lactamase Inhibitors
    Language English
    Publishing date 2022-05-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2022.2071701
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  7. Article ; Online: Current approach to fosfomycin: From bench to bedside.

    Candel, Francisco Javier / Cantón, Rafael

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2018  Volume 37, Issue 1, Page(s) 1–3

    Title translation Uso actual de la fosfomicina: del laboratorio a la práctica clínica.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Fosfomycin/therapeutic use ; Humans ; Pharmaceutical Research
    Chemical Substances Anti-Bacterial Agents ; Fosfomycin (2N81MY12TE)
    Language Spanish
    Publishing date 2018-10-22
    Document type Editorial
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2018.10.002
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  8. Article ; Online: Corrigendum to "Propensity-Score Analysis Reveals that Sex is Not a Prognostic Factor for Mortality in Intensive Care Unit-Admitted Patients with Septic Bacteremia" [International Journal of Infectious Diseases, volume 110 (2021) pages 36-44].

    Ponce-Alonso, Manuel / Fernández-Félix, Borja M / Halperin, Ana / Rodríguez-Domínguez, Mario / Sánchez-Díaz, Ana M / Cantón, Rafael / Muriel, Alfonso / Zamora, Javier / Del Campo, Rosa

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2024  Volume 143, Page(s) 107025

    Language English
    Publishing date 2024-04-05
    Publishing country Canada
    Document type Published Erratum
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2024.107025
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    Zs.A 4516: Show issues Location:
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  9. Article ; Online: Update from the European Committee on Antimicrobial Susceptibility Testing (EUCAST).

    Giske, Christian G / Turnidge, John / Cantón, Rafael / Kahlmeter, Gunnar

    Journal of clinical microbiology

    2021  Volume 60, Issue 3, Page(s) e0027621

    Abstract: The European Committee on Antimicrobial Susceptibility Testing (EUCAST) is an international susceptibility testing committee, organized by the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and functioning as the breakpoint ... ...

    Abstract The European Committee on Antimicrobial Susceptibility Testing (EUCAST) is an international susceptibility testing committee, organized by the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and functioning as the breakpoint advisory committee of the European Medicines Agency (EMA). The original remit of EUCAST was to harmonize European clinical breakpoints, but very soon, the activities expanded beyond the borders of Europe and included newly licensed agents in Europe. Among the milestones were the aggregating of large numbers of MIC distributions, creating software to display these distributions, the EUCAST concept of identifying epidemiological cutoff values (ECOFF), and the development of a EUCAST disk diffusion method. The EUCAST Development Laboratory has played a critical role in the development of antimicrobial susceptibility testing (AST) methodology, including development work for novel antimicrobial agents and for rapid AST directly from blood culture bottles. EUCAST has several standing subcommittees, including for AST in fungi (AFST) and mycobacteria (AMST) and for microorganisms of veterinary interest (VetCAST), and
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents ; Europe ; Fungi ; Humans ; Microbial Sensitivity Tests
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2021-08-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.00276-21
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  10. Article ; Online: Antimicrobial resistance in ICUs: an update in the light of the COVID-19 pandemic.

    Cantón, Rafael / Gijón, Desirèe / Ruiz-Garbajosa, Patricia

    Current opinion in critical care

    2020  Volume 26, Issue 5, Page(s) 433–441

    Abstract: Purpose of review: To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well ... ...

    Abstract Purpose of review: To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of resistance.
    Recent findings: Extended-spectrum and carbapenemase producing Enterobacterales and multidrug and extensive drug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii have increased worldwide. Sequence type (ST)131 Escherichia coli, ST258, ST11, ST10, ST147 and ST307 Klebsiella pneumoniae, ST111, ST175, ST235 and ST244 P. aeruginosa HiRCs are responsible for this increase in the ICUs, and some of them are implicated in the emergence of resistance mechanisms affecting new antimicrobials. A similar situation can be found with European clonal complex 1 and clonal complex 2 of A. baumannii. The high use of antimicrobials during the COVID-19 pandemic, particularly in ICUs, might have a negative influence in future trends of antimicrobial resistance.
    Summary: The increase of antimicrobial resistance in ICUs is mainly due to the spread of HiRCs and is exemplified with the ESKAPE Gram-negative microorganisms. The COVID-19 pandemic might have a negative impact in the increase of antimicrobial resistance and should be monitored through specific surveillance studies in ICUs.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Drug Resistance, Bacterial ; Gram-Negative Bacteria/drug effects ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents
    Keywords covid19
    Language English
    Publishing date 2020-07-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000755
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