LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 21

Search options

  1. Article ; Online: Emory university telehealth neuropsychology development and implementation in response to the COVID-19 pandemic.

    Hewitt, Kelsey C / Loring, David W

    The Clinical neuropsychologist

    2020  Volume 34, Issue 7-8, Page(s) 1352–1366

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Academic Medical Centers/methods ; Academic Medical Centers/trends ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/psychology ; Coronavirus Infections/therapy ; Humans ; Neuropsychological Tests ; Neuropsychology/methods ; Neuropsychology/trends ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/psychology ; Pneumonia, Viral/therapy ; Program Development/methods ; SARS-CoV-2 ; Telemedicine/methods ; Telemedicine/trends
    Keywords covid19
    Language English
    Publishing date 2020-07-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2020.1791960
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: The Montreal Cognitive Assessment: Norms and Reliable Change Indices for Standard and MoCA-22 Administrations.

    Ratcliffe, Lauren N / Hale, Andrew C / McDonald, Taylor / Hewitt, Kelsey C / Nguyen, Christopher M / Spencer, Robert J / Loring, David W

    Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

    2024  

    Abstract: Objective: The Montreal Cognitive Assessment (MoCA) is among the most frequently administered cognitive screening tests, yet demographically diverse normative data are needed for repeated administrations.: Method: Data were obtained from 18,410 ... ...

    Abstract Objective: The Montreal Cognitive Assessment (MoCA) is among the most frequently administered cognitive screening tests, yet demographically diverse normative data are needed for repeated administrations.
    Method: Data were obtained from 18,410 participants using the National Alzheimer's Coordinating Center Uniform Data Set. We developed regression-based norms using Tobit regression to account for ceiling effects, explored test-retest reliability of total scores and by domain stratified by age and diagnosis with Cronbach's alpha, and reported the cumulative change frequencies for individuals with serial MoCA administrations to gage expected change.
    Results: Strong ceiling effects and negative skew were observed at the total score, domain, and item levels for the cognitively normal group, and performances became more normally distributed as the degree of cognitive impairment increased. In regression models, years of education was associated with higher MoCA scores, whereas older age, male sex, Black and American Indian or Alaska Native race, and Hispanic ethnicity were associated with lower predicted scores. Temporal stability was adequate and good at the total score level for the cognitively normal and cognitive disorders groups, respectively, but fell short of reliability standards at the domain level.
    Conclusions: MoCA total scores are adequately reproducible among those with cognitive diagnoses, but domain scores are unstable. Robust regression-based norms should be used to adjust for demographic performance differences, and the limited reliability, along with the ceiling effects and negative skew, should be considered when interpreting MoCA scores.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632972-x
    ISSN 1873-5843 ; 0887-6177
    ISSN (online) 1873-5843
    ISSN 0887-6177
    DOI 10.1093/arclin/acae013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Emory university telehealth neuropsychology development and implementation in response to the COVID-19 pandemic

    Hewitt, Kelsey C. / Loring, David W.

    The Clinical Neuropsychologist

    2020  Volume 34, Issue 7-8, Page(s) 1352–1366

    Keywords Arts and Humanities (miscellaneous) ; Developmental and Educational Psychology ; Clinical Psychology ; Neuropsychology and Physiological Psychology ; Psychiatry and Mental health ; covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2020.1791960
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: Case study of invalid to valid shift in cognitive performance following successful treatment of psychogenic nonepileptic seizure events.

    Drane, Daniel L / Hewitt, Kelsey C / Price, Michele E / Rush, Beth K / Blackmon, Karen / Okada, Noah / Shade, Taylor / Valentin, Edward / Vinson, Joseph / Rosen, Phyllis / Loring, David W

    Journal of clinical and experimental neuropsychology

    2024  Volume 45, Issue 10, Page(s) 1024–1038

    Abstract: Patients with psychogenic nonepileptic seizure (PNES) who fail performance validity testing (PVT) may appear to produce non-valid cognitive profiles. Consequently, they may not get referred to treatment and events persist, with worsening disability and ... ...

    Abstract Patients with psychogenic nonepileptic seizure (PNES) who fail performance validity testing (PVT) may appear to produce non-valid cognitive profiles. Consequently, they may not get referred to treatment and events persist, with worsening disability and high resource utilization. As a result, we report pre- and post-treatment neuropsychological evaluation findings in a 59-year-old woman with a confirmed diagnosis of PNES established using video-EEG monitoring. At pre-treatment baseline neuropsychological evaluation, PNES events occurred weekly to daily. Performance was impaired across PVTs and across multiple cognitive domains. After behavioral intervention specific to PNES, these events substantially reduced in frequency to rare stress-induced flares. Post-treatment neuropsychological evaluation revealed marked improvement of most cognitive and behavioral scores from baseline, and valid PVT scores. We review predisposing, precipitating, and perpetuating factors for PNES and cognitive impairment in this case and discuss the patient's outcome from treatment. Effectively managing PNES events and dissociative tendencies while reducing unnecessary pharmacological interventions appears to have allowed this patient to function closer to her optimal state. This case illustrates the complexity of Functional Neurologic Disorder (FND) clinical presentation and challenges the assumption that suboptimal neuropsychological performance predicts poor treatment engagement and outcome. We showcase the reversibility of PNES and cognitive manifestations of FND using targeted psychotherapeutic interventions, which resulted in reduced disability and associated healthcare costs, as well as re-engagement in life.
    MeSH term(s) Humans ; Female ; Middle Aged ; Seizures/therapy ; Neuropsychological Tests/standards ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/therapy ; Cognitive Dysfunction/physiopathology ; Psychophysiologic Disorders/therapy ; Electroencephalography
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Case Reports ; Review ; Journal Article
    ZDB-ID 605982-x
    ISSN 1744-411X ; 0168-8634 ; 1380-3395
    ISSN (online) 1744-411X
    ISSN 0168-8634 ; 1380-3395
    DOI 10.1080/13803395.2024.2335600
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Emory university telehealth neuropsychology development and implementation in response to the COVID-19 pandemic

    Hewitt, Kelsey C / Loring, David W

    Clin Neuropsychol

    Abstract: Objectives: Emory University has modified its clinical practices across specialties in response to the 2020 COVID-19 pandemic to provide service delivery while maintaining patient, staff, and faculty safety. This report shares current solutions and ... ...

    Abstract Objectives: Emory University has modified its clinical practices across specialties in response to the 2020 COVID-19 pandemic to provide service delivery while maintaining patient, staff, and faculty safety. This report shares current solutions and workarounds associated with telehealth neuropsychology (teleNP) while also recognizing teleNP opportunities.Results: We modified many measures from our traditional assessment protocols so they could be administered through Zoom. To maximize quality control, formal how-to coversheets and manuals were developed for both training and task administration (i.e. navigating Zoom assessment interfaces, practicing adapted test instructions, and troubleshooting).Conclusions: TeleNP has been successfully used to answer referral questions regarding deep brain stimulation (DBS) candidacy in Parkinson's disease patients and presence of mild neurocognitive impairment in patients with subjective memory decline. Our current protocols will continue to evolve with greater experience and are not considered to be a finished product. Nevertheless, development of robust teleNP protocols should expand availability of neuropsychology in both clinical and research applications while simultaneously decreasing assessment burden associated with traveling - sometimes long distances - for diagnostic neuropsychological evaluation.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #651984
    Database COVID19

    Kategorien

  6. Article ; Online: Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: Seizure relief and visual confrontation naming outcomes.

    Hageboutros, Karine / Hewitt, Kelsey C / Lee, Gregory P / Bansal, Aastha / Block, Cady / Pedersen, Nigel P / Willie, Jon T / Loring, David W / Schoenberg, Mike R / Smith, Kris A / Giller, Cole A / Gross, Robert E / Drane, Daniel L

    Epilepsy & behavior : E&B

    2024  Volume 155, Page(s) 109669

    Abstract: The purpose of this study was to systematically examine three different surgical approaches in treating left medial temporal lobe epilepsy (mTLE) (viz., subtemporal selective amygdalohippocampectomy [subSAH], stereotactic laser amygdalohippocampotomy [ ... ...

    Abstract The purpose of this study was to systematically examine three different surgical approaches in treating left medial temporal lobe epilepsy (mTLE) (viz., subtemporal selective amygdalohippocampectomy [subSAH], stereotactic laser amygdalohippocampotomy [SLAH], and anterior temporal lobectomy [ATL]), to determine which procedures are most favorable in terms of visual confrontation naming and seizure relief outcome. This was a retrospective study of 33 adults with intractable mTLE who underwent left temporal lobe surgery at three different epilepsy surgery centers who also underwent pre-, and at least 6-month post-surgical neuropsychological testing. Measures included the Boston Naming Test (BNT) and the Engel Epilepsy Surgery Outcome Scale. Fisher's exact tests revealed a statistically significant decline in naming in ATLs compared to SLAHs, but no other significant group differences. 82% of ATL and 36% of subSAH patients showed a significant naming decline whereas no SLAH patient (0%) had a significant naming decline. Significant postoperative naming improvement was seen in 36% of SLAH patients in contrast to 9% improvement in subSAH patients and 0% improvement in ATLs. Finally, there were no statistically significant differences between surgical approaches with regard to seizure freedom outcome, although there was a trend towards better seizure relief outcome among the ATL patients. Results support a possible benefit of SLAH in preserving visual confrontation naming after left TLE surgery. While result interpretation is limited by the small sample size, findings suggest outcome is likely to differ by surgical approach, and that further research on cognitive and seizure freedom outcomes is needed to inform patients and providers of potential risks and benefits with each.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2024.109669
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Classification statistics of the Montreal Cognitive Assessment (MoCA): Are we interpreting the MoCA correctly?

    Ratcliffe, Lauren N / McDonald, Taylor / Robinson, Brittany / Sass, John R / Loring, David W / Hewitt, Kelsey C

    The Clinical neuropsychologist

    2022  Volume 37, Issue 3, Page(s) 562–576

    Abstract: Objective: The Montreal Cognitive Assessment (MoCA) is a common cognitive screener for detecting mild cognitive impairment (MCI). However, previously suggested cutoff scores of 26/30 and above is often criticized and lacks racial diversity. The purpose ... ...

    Abstract Objective: The Montreal Cognitive Assessment (MoCA) is a common cognitive screener for detecting mild cognitive impairment (MCI). However, previously suggested cutoff scores of 26/30 and above is often criticized and lacks racial diversity. The purpose of this study is to investigate the potential influence of race on MoCA classification cutoff score accuracy.
    Method: Data were obtained from the National Alzheimer's Coordinating Center (NACC) Uniform Data Set and yielded 4,758 total participants. Participants were predominately White (82.8%) and female (61.7%) with a mean age of 69.3 years (
    Results: Sensitivity and specificity analyses revealed that when using the cutoff score of ≤26/30, the MoCA correctly classified 73.2% of White cognitively normal participants and 83.1% of White MCI participants. In contrast, this criterion correctly classified 40.5% of Black cognitively normal participants and 90.8% of Black MCI participants. Our sample was highly educated; therefore, we did not observe significant differences in scores when accounting for education across race. Classification statistics are presented.
    Conclusions: Black participants were misclassified at a higher rate than White participants when applying the ≤26/30 cutoff score. We suggest cutoff scores of ≤25/30 be applied to White persons and ≤22/30 for Black persons. These findings highlight the need for racially stratified population-based norms given the high misclassification of Black participants without such adjustment.
    MeSH term(s) Humans ; Female ; Aged ; Neuropsychological Tests ; Mental Status and Dementia Tests ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/psychology ; Sensitivity and Specificity ; Neurologic Examination
    Language English
    Publishing date 2022-06-14
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2022.2086487
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Transitioning to telehealth neuropsychology service: Considerations across adult and pediatric care settings.

    Hewitt, Kelsey C / Rodgin, Sandra / Loring, David W / Pritchard, Alison E / Jacobson, Lisa A

    The Clinical neuropsychologist

    2020  Volume 34, Issue 7-8, Page(s) 1335–1351

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Humans ; Male ; Neuropsychological Tests ; Neuropsychology/methods ; Neuropsychology/trends ; Pandemics ; Patient Transfer/methods ; Patient Transfer/trends ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Telemedicine/trends
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2020.1811891
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Open surgery or laser interstitial thermal therapy for low-grade epilepsy-associated tumors of the temporal lobe: A single-institution consecutive series.

    Hedaya, Alexander A / Hewitt, Kelsey C / Hu, Ranliang / Epstein, Charles M / Gross, Robert E / Drane, Daniel L / Willie, Jon T

    Epilepsy & behavior : E&B

    2022  Volume 130, Page(s) 108659

    Abstract: Outcomes of treating low-grade epilepsy-associated tumors (LEATs) in the temporal lobe with MRI-guided laser interstitial thermal therapy (MRgLITT) remain poorly characterized. This study aimed to compare the safety and effectiveness of treating temporal ...

    Abstract Outcomes of treating low-grade epilepsy-associated tumors (LEATs) in the temporal lobe with MRI-guided laser interstitial thermal therapy (MRgLITT) remain poorly characterized. This study aimed to compare the safety and effectiveness of treating temporal lobe LEATs with MRgLITT versus open resection in a consecutive single-institution series. We reviewed all adult patients with epilepsy that underwent surgery for temporal lobe LEATs at our institution between 2002 and 2019, during which time we switched from open surgery to MRgLITT. Surgical outcome was categorized by Engel classification at >12mo follow-up and Kaplan-Meir analysis of seizure freedom. We recorded hospital length of stay, adverse events, and available neuropsychological results. Of 14 total patients, 7 underwent 9 open resections, 6 patients underwent MRgLITT alone, and 1 patient underwent an open resection followed by MRgLITT. Baseline group demographics differed and were notable for preoperative duration of epilepsy of 9.0 years (range 1-36) for open resection versus 14.0 years (range 2-34) for MRgLITT. Median length of stay was one day shorter for MRgLITT compared to open resection (p=<.0001). There were no major adverse events in the series, but there were fewer minor adverse events following MRgLITT. At 12mo follow-up, 50% (5/10) of patients undergoing open resection and 57% (4/7) of patients undergoing MRgLITT were free of disabling seizures (Engel I). When comparing patients who underwent similar procedures in the dominant temporal lobe, patients undergoing MRgLITT had fewer and milder material-specific neuropsychological declines than patients undergoing open resections. In this small series, MRgLITT was comparably safe and effective relative to open resection of temporal lobe LEATs.
    MeSH term(s) Adult ; Drug Resistant Epilepsy/surgery ; Epilepsy/etiology ; Epilepsy/pathology ; Epilepsy/surgery ; Epilepsy, Temporal Lobe/complications ; Epilepsy, Temporal Lobe/pathology ; Epilepsy, Temporal Lobe/surgery ; Humans ; Laser Therapy/methods ; Lasers ; Neoplasms ; Temporal Lobe/pathology ; Temporal Lobe/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2022.108659
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Depression and anxiety in caregivers of patients with functional seizures.

    Tsamakis, Konstantinos / Teagarden, Diane L / Villarreal, Hannah K / Evans, Latasha / Morton, Matthew L / Janocko, Nicholas J / Groover, Olivia / Hewitt, Kelsey C / Price, Michele E / Loring, David W / Drane, Daniel L / Karakis, Ioannis

    Epileptic disorders : international epilepsy journal with videotape

    2023  Volume 25, Issue 2, Page(s) 200–208

    Abstract: Objective: Contrary to patients, the psychological impact of functional seizures to caregivers has not been adequately investigated. This study aimed to evaluate the rates and determinants of depression and anxiety in caregivers of patients with ... ...

    Abstract Objective: Contrary to patients, the psychological impact of functional seizures to caregivers has not been adequately investigated. This study aimed to evaluate the rates and determinants of depression and anxiety in caregivers of patients with functional seizures.
    Methods: Patients with functional seizures and their caregivers completed surveys about demographic, disease-related, and psychosocial characteristics. Rates and determinants of depression and anxiety were evaluated using the Beck Depression and Anxiety Inventory scores as dependent variables and patient and caregiver characteristics as independent variables.
    Results: Twenty-nine patients (76% female, mean age of 37 years) and their caregivers (59% female, mean age of 43 years) were recruited. Symptoms of anxiety and/or depression were present in 96% of patients (96% depression, 92% anxiety) and 59% of caregivers (52% depression, 50% anxiety). Specifically, 31% of caregivers manifested mild depression, 14% moderate depression, and 7% severe depression, whereas 48% were not depressed. Similarly, 14% of caregivers manifested mild anxiety, 29% moderate anxiety, and 7% severe anxiety, whereas 50% were not anxious. Patient and caregiver depression levels strongly correlated (r = .73, p < .0001). The presence of anxiety and depression in the caregiver was associated with male patient gender (p = .02), patient depression level (p = .002), the caregiver being a parent or sibling (p = .02), and caregiver burden (p = .0009).
    Significance: Caregivers of patients with functional seizures experience high rates of anxiety and depression, explained by specific demographic and psychosocial factors that could act as intervention targets.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Caregivers ; Depression ; Anxiety/epidemiology ; Anxiety/psychology ; Seizures ; Surveys and Questionnaires ; Quality of Life/psychology
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2086797-9
    ISSN 1950-6945 ; 1294-9361
    ISSN (online) 1950-6945
    ISSN 1294-9361
    DOI 10.1002/epd2.20014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top