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  1. Article ; Online: A GAN-BO-XGBoost model for high-quality patents identification.

    Wu, Zengyuan / Zhao, Jiali / Li, Ying / Wang, Zelin / He, Bin / Chen, Liang

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9560

    Abstract: ... algorithm (XGBoost) with Bayesian optimization (BO) is used to identify high-quality patents. For clarity ... this model is called a GAN-BO-XGBoost model. To test the effectiveness of above model, we use patent data ... between our proposed model and other models. The results show that GAN-BO-XGBoost model performs better ...

    Abstract The number of patents increases quickly, while more and more low-quality patents are emerging. It's important to identify high-quality patents from massive data quickly and accurately for organizational R&D decision-making and patent layout. However, due to low percentage of high-quality patents, it is challenging to identify them efficiently. In order to solve above problem, we reconstruct the existing index system for identifying high-quality patents by adding 4 features from technological strength of patentees. Furthermore, we propose an improved model by integrating resampling technique and ensemble learning algorithm. First, generative adversarial networks (GAN) are used to expand minority samples. Second, Extreme Gradient Boosting algorithm (XGBoost) with Bayesian optimization (BO) is used to identify high-quality patents. For clarity, this model is called a GAN-BO-XGBoost model. To test the effectiveness of above model, we use patent data in field of lithography technology. Tenfold cross-validation is carried out to evaluate the performance between our proposed model and other models. The results show that GAN-BO-XGBoost model performs better and it's more stable than other models.
    Language English
    Publishing date 2024-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-60173-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Directional Construction of New Nonlinear Optical Bifunctional Units through Molecular Engineering Design Inspired by the B₃O₇-Typed Configuration

    Fan, Huixin / Lin, Chensheng / Liang, Fei / Tian, Haotian / Huang, Shijun / Zhou, Yuqiao / Ke, Shixian / Li, Bingxuan / Ye, Ning / Luo, Min

    ACS applied materials & interfaces. 2022 July 07, v. 14, no. 28

    2022  

    Abstract: ... with a highly analogous structure to the B₃O₇ group and its derivate B(C₂N₅)₂ unit with a configuration of B₅O₁₀ ...

    Abstract Studies on new functional structural units with both large hyperpolarizability and high anisotropy are essentially important for finding high-performance nonlinear optical (NLO) materials and enriching the material systems. Under the guidance of the “structure-analogue” strategy, the work utilizes the molecular engineering approach to direct the construction of target units, BC₂N₅O₂ and B(C₂N₅)₂ units. The BC₂N₅O₂ unit with a highly analogous structure to the B₃O₇ group and its derivate B(C₂N₅)₂ unit with a configuration of B₅O₁₀ group are designed as NLO-active units. Furthermore, two compounds with these new NLO-active units, BC₂N₅H₆(OH)₂·H₂O (I) and B(C₂N₅H₆.₅)₂(NO₃)₂ (II), are synthesized, successfully. These compounds exhibit excellent properties with second-harmonic generation (SHG) responses ranging from 0.5 to 5.9 times that of KDP and large birefringence (ΔnI = 0.181 @ 546.1 nm and ΔnII = 0.148 @ 546.1 nm). Theoretical calculations prove that the BC₂N₅O₂ and B(C₂N₅)₂ units make great contributions to the SHG effects and birefringence, which confirms that the BC₂N₅O₂ and B(C₂N₅)₂ units are novel NLO bifunctional units and could be excellent fundamental building blocks to construct amounts of novel NLO and birefringence crystals. Our studies would enlighten the research studies on biguanide complexes of boron.
    Keywords anisotropy ; boron ; crystals ; design ; engineers ; exhibitions ; materials
    Language English
    Dates of publication 2022-0707
    Size p. 32270-32278.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021/acsami.2c08495
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Impacts of 5d electron binding energy and electron–phonon coupling on luminescence of Ce³⁺ in Li₆Y(BO₃)₃

    Ou, Yiyi / Weijie Zhou / Dejian Hou / Mikhail G. Brik / Pieter Dorenbos / Yan Huang / Hongbin Liang

    RSC advances. 2019 Mar. 11, v. 9, no. 14

    2019  

    Abstract: ... vacuum ultraviolet-ultraviolet-visible (VUV-UV-vis) luminescence properties of Li₆Y(BO₃)₃ (LYBO):Ce³⁺ ... of ∼6, which indicates a strong electron–phonon interaction of Ce³⁺ luminescence in the Li₆Y(BO₃)₃ host ...

    Abstract In this work, the crystal structure and electronic structure as well as the synchrotron radiation vacuum ultraviolet-ultraviolet-visible (VUV-UV-vis) luminescence properties of Li₆Y(BO₃)₃ (LYBO):Ce³⁺ phosphors were investigated in detail. The Rietveld refinement and DFT calculation reveal the P2₁/c monoclinic crystal phase and the direct band gap of the LYBO compound, respectively. Only one kind of Ce³⁺ 4f–5d transition is resolved in terms of the low temperature VUV-UV excitation, UV-vis emission spectra and luminescence decay curves. Furthermore, by constructing the vacuum referred binding energy (VRBE) scheme and applying the frequency-degenerate vibrational model, the impacts of 5d electron binding energy and electron–phonon coupling on luminescence of Ce³⁺ in LYBO are analysed. The results show that the Ce³⁺ emission in LYBO possesses a moderate intrinsic thermal stability. With the increase in concentration, the thermal stability of the emission gets worse due to the possible thermally-activated concentration quenching. In addition, the simulation of Ce³⁺ emission profile at low temperature reveals that the 4f–5d electronic transitions of Ce³⁺ ions can be treated to couple with one frequency-degenerate vibrational mode having the effective phonon energy of ∼257 cm⁻¹ with the corresponding Huang–Rhys parameter of ∼6, which indicates a strong electron–phonon interaction of Ce³⁺ luminescence in the Li₆Y(BO₃)₃ host. Finally, the X-ray excited luminescence spectrum of the LYBO:5%Ce³⁺ phosphor is measured to check the potential scintillator applications.
    Keywords X-radiation ; cerium ; crystal structure ; energy ; ions ; luminescence ; models ; temperature ; thermal stability
    Language English
    Dates of publication 2019-0311
    Size p. 7908-7915.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c9ra00381a
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: A novel inorganic-organic hybrid borate, poly{[Na(2)(C(4)H(2)O(4))(H(3)BO(3))(H(2)O)(4)]·H(3)BO(3)}.

    Shao, Zhi-Dong / Zhang, Yu-Qi / Wu, Shu-Li / Liang, Yun-Xiao

    Acta crystallographica. Section E, Structure reports online

    2010  Volume 66, Issue Pt 11, Page(s) m1460–1

    Abstract: The structure of the title compound, catena-poly[[[di-μ-aqua-μ-fumarato-μ-(boric acid)-disodium]-di-μ-aqua] boric acid monosolvate], contains two crystallographically independent Na(+) cations, each being six-coordinated by one fumarate O atom, one boric ...

    Abstract The structure of the title compound, catena-poly[[[di-μ-aqua-μ-fumarato-μ-(boric acid)-disodium]-di-μ-aqua] boric acid monosolvate], contains two crystallographically independent Na(+) cations, each being six-coordinated by one fumarate O atom, one boric acid O atom and four water O atoms in a distorted octa-hedral geometry. Adjacent [NaO(2)(OH(2))(4)] units share edges and are linked into chains propagating parallel to [100]. The free boric acid mol-ecules are connected to the chains through strong inter-molecular O-H⋯O hydrogen bonds. Additional O-H⋯O hydrogen bonds between the water mol-ecules, the free and coordinated boric acid mol-ecules and the fumarate anion lead to the formation of a three-dimensional supra-molecular structure. With the exception of the two water mol-ecules, all other atoms lie on mirror planes.
    Language English
    Publishing date 2010-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 1600-5368 ; 1600-5368
    ISSN (online) 1600-5368
    ISSN 1600-5368
    DOI 10.1107/S1600536810041358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Giant Magnetoelectric Effect in HoAl_3(BO_3)_4

    Liang, K. -C. / Chaudhury, R. P. / Lorenz, B. / Sun, Y. Y. / Bezmaternykh, L. N. / Temerov, V. L. / Chu, C. W.

    2011  

    Abstract: A giant magnetoelectric polarization is found in HoAl$_3$(BO$_3$)$_4$. The polarization ... BO$_3$)$_4$ is extremely strong and that the magnetic field causes a large polar distortion ...

    Abstract A giant magnetoelectric polarization is found in HoAl$_3$(BO$_3$)$_4$. The polarization in transverse field geometry at 70 kOe reaches 3600 $\mu C/m^2$ which is significantly higher than reported values of linear magnetoelectric or even multiferroic compounds. The magnetostrictive effect is also measured and compared with the magnetoelectricity. The results show that spin-lattice coupling in HoAl$_3$(BO$_3$)$_4$ is extremely strong and that the magnetic field causes a large polar distortion of the ionic positions in the unit cell.

    Comment: 4 pages, 4 figures
    Keywords Condensed Matter - Strongly Correlated Electrons ; Condensed Matter - Materials Science
    Publishing date 2011-05-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Membrane biogenesis of subunit II of cytochrome bo oxidase: contrasting requirements for insertion of N-terminal and C-terminal domains.

    Celebi, Nil / Yi, Liang / Facey, Sandra J / Kuhn, Andreas / Dalbey, Ross E

    Journal of molecular biology

    2006  Volume 357, Issue 5, Page(s) 1428–1436

    Abstract: ... a crucial role in the assembly of the bacterial subunit II (CyoA) of cytochrome bo oxidase. CyoA spans ...

    Abstract The membrane assembly of the respiratory complexes requires the membrane insertases Oxa1 in mitochondria and YidC in bacteria. Oxa1 is responsible for the insertion of the mitochondrial cytochrome c oxidase subunit II (CoxII). Here, we investigated whether YidC, the bacterial Oxa1 homolog, plays a crucial role in the assembly of the bacterial subunit II (CyoA) of cytochrome bo oxidase. CyoA spans the membrane twice and is made with a cleavable signal peptide. We find that translocation of the short N-terminal domain of CyoA is YidC-dependent. In contrast, both the SecA/SecYEG complex and YidC are required for translocation of the large C-terminal domain. By studying the N-terminal domain of CyoA alone, we find that translocation is unaffected when SecE is depleted, suggesting that the YidC insertase on its own catalyzes membrane insertion of the N-terminal region of CyoA. Strikingly, we find that the translocation of the N-terminal domain is a prerequisite for translocation of the C-terminal domain in the full-length CyoA protein because translocation of the large C-terminal domain alone in a truncated CyoA derivative was observed in the absence of YidC. This work shows that the distinct domains of CyoA have different translocation requirements (YidC only and Sec/YidC) and confirms that the membrane biogenesis of subunit II of cytochrome oxidase in bacteria and mitochondria have conserved features.
    MeSH term(s) Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Membrane/metabolism ; Electron Transport Complex IV/biosynthesis ; Electron Transport Complex IV/chemistry ; Electron Transport Complex IV/genetics ; Escherichia coli/enzymology ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Evolution, Molecular ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Mitochondria/enzymology ; Protein Conformation ; Protein Precursors/chemistry ; Protein Precursors/genetics ; Protein Precursors/metabolism ; Protein Sorting Signals ; Protein Subunits/biosynthesis ; Protein Subunits/chemistry ; Protein Subunits/genetics ; SEC Translocation Channels
    Chemical Substances Bacterial Proteins ; Escherichia coli Proteins ; Membrane Transport Proteins ; Protein Precursors ; Protein Sorting Signals ; Protein Subunits ; SEC Translocation Channels ; YIDC protein, E coli ; SecA protein, Bacteria (119129-39-4) ; cytochrome o oxidase (EC 1.9.3.-) ; Electron Transport Complex IV (EC 1.9.3.1) ; Adenosine Triphosphatases (EC 3.6.1.-)
    Language English
    Publishing date 2006-04-14
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80229-3
    ISSN 1089-8638 ; 0022-2836
    ISSN (online) 1089-8638
    ISSN 0022-2836
    DOI 10.1016/j.jmb.2006.01.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Yi xue chuan bo xue

    Liang, Haocai

    1989  

    Title translation Medical communication.
    Author's details zhu bian Liang Haocai
    MeSH term(s) Communication ; Medicine ; Information Services
    Language Chinese
    Size 45 p. :, ill.
    Edition Di 1 ban.
    Publisher Shanghai ke xue ji shu chu ban she
    Publishing place Shanghai
    Document type Book
    ISBN 9787532315109 ; 753231510X
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article ; Online: An autophagy-independent role of ULK1/ULK2 in mechanotransduction and breast cancer cell migration.

    Liang, Peigang / Wang, Bo

    Autophagy

    2024  , Page(s) 1–2

    Abstract: The progression of breast cancer is often accompanied by changes in extracellular matrix stiffness and cell adhesion ability, which are closely related to cellular mechanotransduction. However, the underlying regulatory mechanisms remain mysterious. Our ... ...

    Abstract The progression of breast cancer is often accompanied by changes in extracellular matrix stiffness and cell adhesion ability, which are closely related to cellular mechanotransduction. However, the underlying regulatory mechanisms remain mysterious. Our study reveals that the macroautophagy/autophagy-inducing kinases, ULK1 and ULK2, inhibit the assembly of focal adhesions and F-actin by phosphorylating the adhesion protein PXN, to prevent breast cancer cell migration in an autophagy-independent fashion. Interestingly, ULK1/ULK2-mediated serine phosphorylation of PXN counteracts PXN phosphorylation at the adjacent tyrosine residues by PTK2 and SRC, to gatekeep cellular mechanotransduction. Our research establishes a new function of ULK1/ULK2 in governing cellular mechanotransduction that might be harnessed for treating breast cancer.
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2023.2300916
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Treatment of refractory hand eczema by dupilumab: A case report.

    Dong, Hanyue / Chen, Wei / Liang, Bo / Li, Hongmin

    International journal of dermatology

    2024  

    Language English
    Publishing date 2024-02-25
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.17098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: MicroR-380-3p Reduces Sepsis-Induced Acute Kidney Injury via Regulating RAB1P to Restrain NF-κB Pathway.

    Liang, Jifang / Li, Bo / Xia, Yanmei

    The Tohoku journal of experimental medicine

    2024  

    Language English
    Publishing date 2024-01-12
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 123477-8
    ISSN 1349-3329 ; 0040-8727
    ISSN (online) 1349-3329
    ISSN 0040-8727
    DOI 10.1620/tjem.2023.J106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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