LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article: Screening and GC-MS profiling of ethanolic extract of

    Starlin, Thangarajan / Prabha, Poochi Saravana / Thayakumar, Basanth Kumar Allen / Gopalakrishnan, Velliyur Kanniappan

    Bioinformation

    2019  Volume 15, Issue 6, Page(s) 425–429

    Abstract: Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many ...

    Abstract Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.
    Language English
    Publishing date 2019-06-15
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630015425
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Employing bioactive compounds derived from

    Poochi, Saravana Prabha / Easwaran, Murugesh / Balasubramanian, Balamuralikrishnan / Anbuselvam, Mohan / Meyyazhagan, Arun / Park, Sungkwon / Bhotla, Haripriya Kuchi / Anbuselvam, Jeeva / Arumugam, Vijaya Anand / Keshavarao, Sasikala / Kanniyappan, Gopalakrishnan Velliyur / Pappusamy, Manikantan / Kaul, Tanushri

    Food frontiers

    2020  Volume 1, Issue 2, Page(s) 168–179

    Abstract: Angiotensin converting enzyme 2 (ACE2) and main protease ( ... ...

    Abstract Angiotensin converting enzyme 2 (ACE2) and main protease (M
    Keywords covid19
    Language English
    Publishing date 2020-07-06
    Publishing country United States
    Document type Journal Article
    ISSN 2643-8429
    ISSN (online) 2643-8429
    DOI 10.1002/fft2.29
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Employing bioactive compounds derived from Ipomoea obscura (L.) to evaluate potential inhibitor for SARS‐CoV‐2 main protease and ACE2 protein

    Poochi, Saravana Prabha / Easwaran, Murugesh / Balasubramanian, Balamuralikrishnan / Anbuselvam, Mohan / Meyyazhagan, Arun / Park, Sungkwon / Bhotla, Haripriya Kuchi / Anbuselvam, Jeeva / Arumugam, Vijaya Anand / Keshavarao, Sasikala / Kanniyappan, Gopalakrishnan Velliyur / Pappusamy, Manikantan / Kaul, Tanushri

    Food Frontiers

    2020  Volume 1, Issue 2, Page(s) 168–179

    Keywords covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 2643-8429
    DOI 10.1002/fft2.29
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article: Employing bioactive compounds derived from Ipomoea obscura (L.) to evaluate potential inhibitor for SARS-CoV-2 main protease and ACE2 protein

    Poochi, Saravana Prabha / Easwaran, Murugesh / Balasubramanian, Balamuralikrishnan / Anbuselvam, Mohan / Meyyazhagan, Arun / Park, Sungkwon / Bhotla, Haripriya Kuchi / Anbuselvam, Jeeva / Arumugam, Vijaya Anand / Keshavarao, Sasikala / Kanniyappan, Gopalakrishnan Velliyur / Pappusamy, Manikantan / Kaul, Tanushri

    Abstract: Angiotensin converting enzyme 2 (ACE2) and main protease (MPro) are significant target proteins, mainly involved in the attachment of viral genome to host cells and aid in replication of severe acute respiratory syndrome-coronaviruses or SARS-CoV genome. ...

    Abstract Angiotensin converting enzyme 2 (ACE2) and main protease (MPro) are significant target proteins, mainly involved in the attachment of viral genome to host cells and aid in replication of severe acute respiratory syndrome-coronaviruses or SARS-CoV genome. In the present study, we identified 11 potent bioactive compounds from ethanolic leaf extract of Ipomoea obscura (L.) by using GC-MS analysis. These potential bioactive compounds were considered for molecular docking studies against ACE2 and MPro target proteins to determine the antiviral effects against SARS-COV. Results exhibits that among 11 compounds from I. obscura (L.), urso-deoxycholic acid, demeclocycline, tetracycline, chlorotetracycline, and ethyl iso-allocholate had potential viral inhibitory activity. Hence, the present findings suggested that chemical constitution present in I. obscura (L.) will address inhibition of corona viral replication in host cells.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #728082
    Database COVID19

    Kategorien

To top