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  1. Article: COVID-19 associated pancreatitis: A mini case-series.

    Schembri Higgans, Jessica / Bowman, Sarah / Abela, Jo-Etienne

    International journal of surgery case reports

    2021  Volume 87, Page(s) 106429

    Abstract: Introduction: One of the recognized causes of acute pancreatitis is viral-induced pancreatitis. The SARS-COV-2 virus has been linked to pancreatic injury and hence the causation of acute pancreatitis. This paper reports three cases of acute pancreatitis ...

    Abstract Introduction: One of the recognized causes of acute pancreatitis is viral-induced pancreatitis. The SARS-COV-2 virus has been linked to pancreatic injury and hence the causation of acute pancreatitis. This paper reports three cases of acute pancreatitis linked to COVID-19 infection adding to serving to further consolidate evidence.
    Case presentation: Three patients aged between 63 and 87 years were diagnosed with acute pancreatitis and concomitant or previous COVID-19 infection. Criteria for diagnosis of pancreatitis were according to the revised Atlanta criteria. None of the patients had had previous episodes of pancreatitis and other aetiologies were not suggestive. The patients were not vaccinated against SARS-CoV-2. Supportive treatment was instituted for the three patients, and all made an uneventful recovery. Mean hospital stay was 4 days.
    Discussion: The diagnosis of acute pancreatitis in the presented cases is being linked to COVID-19 infection, as other causes were not evident. There is however a confounding factor, as the patient in case 2 had slightly elevated triglyceride levels and had been on long-term low dose atorvastatin, both of which are associated with a low risk of acute pancreatitis. However, she had never had pancreatitis prior to this presentation.
    Conclusion: The novel virus SARS-COV-2 has also been linked to pancreatic damage and thus a possible causative factor in acute pancreatitis. This mini-case series presents three cases of acute pancreatitis in COVID-19 positive patients, in the absence of other risk factors. This phenomenon linking COVID-19 and pancreatitis has been expounded by other case reports and cohort studies from around the world. It is reasonable to acknowledge that, like other viruses, SARS CoV-2 may cause acute pancreatitis, although sounder evidence from the international community needs to be compiled.
    Language English
    Publishing date 2021-09-22
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2021.106429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Denture impacted in the oesophagus for 9 months

    John Anderson / Jo-Etienne Abela

    Clinics and Practice, Vol 1, Iss

    successful endoscopic retrieval

    2011  Volume 4

    Abstract: This case report describes the presentation and successful endoscopic retrieval of an impacted denture plate from the distal oesophagus where it had been in-situ for nine months. ...

    Abstract This case report describes the presentation and successful endoscopic retrieval of an impacted denture plate from the distal oesophagus where it had been in-situ for nine months.
    Keywords impacted denture ; endoscopic retrieval ; Medicine (General) ; R5-920
    Language English
    Publishing date 2011-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Denture impacted in the oesophagus for 9 months: successful endoscopic retrieval.

    Anderson, John E / Abela, Jo-Etienne

    Clinics and practice

    2011  Volume 1, Issue 4, Page(s) e96

    Abstract: This case report describes the presentation and successful endoscopic retrieval of an impacted denture plate from the distal oesophagus where it had been in-situ for nine months. ...

    Abstract This case report describes the presentation and successful endoscopic retrieval of an impacted denture plate from the distal oesophagus where it had been in-situ for nine months.
    Language English
    Publishing date 2011-11-02
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2605724-4
    ISSN 2039-7283 ; 2039-7275
    ISSN (online) 2039-7283
    ISSN 2039-7275
    DOI 10.4081/cp.2011.e96
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Haemobilia causing cholangitis in a patient on dual anti-platelet treatment suffering from acute acalculous cholecystitis.

    Luhmann, Andreas / Buter, Anton / Abela, Jo-Etienne

    International journal of surgery case reports

    2013  Volume 4, Issue 4, Page(s) 368–370

    Abstract: Introduction: Haemobilia is a rare cause of upper gastro-intestinal haemorrhage which can be difficult to diagnose.: Presentation of case: We present the case of a patient who suffered from acute acalculous cholecystitis while on dual anti-platelet ... ...

    Abstract Introduction: Haemobilia is a rare cause of upper gastro-intestinal haemorrhage which can be difficult to diagnose.
    Presentation of case: We present the case of a patient who suffered from acute acalculous cholecystitis while on dual anti-platelet therapy with aspirin and clopidogrel. We describe the diagnostic and treatment challenges arising from the patient's complicated past history and the steps leading to the diagnosis of haemobilia causing biliary obstruction and cholangitis. Our patient did not, at any point, manifest anaemia or evidence of haemorrhage.
    Discussion: Haemobilia has a varied aetiology. To our knowledge there is no association with dual anti-platelet treatment in the literature to date. Diagnosis is difficult and relies on multiple modalities. In our patient the final diagnosis was only made in the course of open bile duct exploration.
    Conclusion: In acute biliary obstruction we recommend the consideration of haemobilia in the differential diagnosis, especially in patients with a bleeding tendency.
    Language English
    Publishing date 2013-02-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2012.12.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Endo-biliary stents for benign disease: not always benign after all!

    Abela, Jo-Etienne / Anderson, John E / Whalen, Henry R / Mitchell, Kenneth G

    Clinics and practice

    2011  Volume 1, Issue 4, Page(s) e102

    Abstract: This case report describes the presentation, management and treatment of a patient who suffered small bowel perforation due to the migration of his biliary stent which had been inserted for benign disease. ...

    Abstract This case report describes the presentation, management and treatment of a patient who suffered small bowel perforation due to the migration of his biliary stent which had been inserted for benign disease.
    Language English
    Publishing date 2011-11-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2605724-4
    ISSN 2039-7283 ; 2039-7275
    ISSN (online) 2039-7283
    ISSN 2039-7275
    DOI 10.4081/cp.2011.e102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Endo-biliary stents for benign disease

    Jo-Etienne Abela / John E. Anderson / Henry R. Whalen / Kenneth G. Mitchell

    Clinics and Practice, Vol 1, Iss

    not always benign after all!

    2011  Volume 4

    Abstract: This case report describes the presentation, management and treatment of a patient who suffered small bowel perforation due to the migration of his biliary stent which had been inserted for benign disease. ...

    Abstract This case report describes the presentation, management and treatment of a patient who suffered small bowel perforation due to the migration of his biliary stent which had been inserted for benign disease.
    Keywords slipped endo-biliary stent ; Medicine (General) ; R5-920
    Language English
    Publishing date 2011-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A case of a large, painless retroperitoneal mass causing hydronephrosis and biliary obstruction.

    Attard, Joseph / Azzopardi, Christine / Cortis, Kelvin / Abela, Jo Etienne

    BMJ case reports

    2015  Volume 2015

    MeSH term(s) Cholestasis/etiology ; Humans ; Hydronephrosis/etiology ; Male ; Medical Illustration ; Middle Aged ; Retroperitoneal Neoplasms/complications ; Retroperitoneal Neoplasms/pathology ; Retroperitoneal Neoplasms/surgery
    Language English
    Publishing date 2015-10-15
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-212422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Systematic four-quadrant biopsy detects Barrett's dysplasia in more patients than nonsystematic biopsy.

    Abela, Jo-Etienne / Going, James J / Mackenzie, John F / McKernan, Margaret / O'Mahoney, Sylvia / Stuart, Robert C

    The American journal of gastroenterology

    2008  Volume 103, Issue 4, Page(s) 850–855

    Abstract: Aims: To compare detection of Barrett's dysplasia and adenocarcinoma by systematic versus nonsystematic surveillance biopsy protocols.: Methods: Upper GI consultation and open-access endoscopy are provided jointly at Glasgow Royal Infirmary by ... ...

    Abstract Aims: To compare detection of Barrett's dysplasia and adenocarcinoma by systematic versus nonsystematic surveillance biopsy protocols.
    Methods: Upper GI consultation and open-access endoscopy are provided jointly at Glasgow Royal Infirmary by medical and surgical teams. The surgical team adopted annual systematic four-quadrant biopsy Barrett's surveillance in 1995. The medical team continued annual Barrett's surveillance with nonsystematic biopsy until 2004. We compare detection of Barrett's dysplasia and esophageal adenocarcinoma in unselected patients by these two biopsy strategies over 10 yr. All patients had > or = 3 cm Barrett's esophagus and histological proof of intestinal metaplasia. Patients referred for dysplasia management or with prevalent adenocarcinoma were excluded. Cohort A (N = 180) had four-quadrant biopsy every 2 cm while cohort B (N = 182) had nonsystematic biopsies.
    Results: Cohort A versus cohort B: Median number of biopsies per endoscopy: 16 versus 4. Prevalence of low-grade dysplasia (per patient): 18.9% versus 1.6% (P << 0.001). Prevalence of high-grade dysplasia: 2.8% versus 0% (P = 0.03). Incidence of low-grade dysplasia: 2.2% versus 6.6% (NS). Incidence of high-grade dysplasia: 2.8% versus 0% (P = 0.03). Nine cohort A patients (total 5%, 1.4% per patient-year) were treated for HGD (eight endoscopically, one by esophagectomy). Two had intramucosal adenocarcinoma. No cohort A patient developed advanced cancer but three cohort B patients developed and died of invasive Barrett's adenocarcinoma (0.6% per patient-year).
    Conclusions: Patient age, gender, Barrett's segment length, and follow-up were similar (though not identical) in both cohorts, but confounding seems unlikely to account for a 13-fold difference in detection of prevalent dysplasia between the two groups. Our data support the hypothesis that systematic four-quadrant biopsy is considerably more effective than nonsystematic biopsy sampling in detecting Barrett's dysplasia and early adenocarcinoma. Greater biopsy numbers and the systematic pattern of biopsy taking may both contribute to this greater effectiveness.
    MeSH term(s) Adenocarcinoma/pathology ; Barrett Esophagus/pathology ; Biopsy/methods ; Esophagoscopy ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Statistics, Nonparametric
    Language English
    Publishing date 2008-04
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.1111/j.1572-0241.2007.01746.x
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    Ui V Zs.36: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Endoscopic mucosal resection for gastroesophageal cancer in a U.K. population. Long-term follow-up of a consecutive series.

    Crumley, Andrew B C / Going, James J / McEwan, Kerryanne / McKernan, Margaret / Abela, Jo-Etienne / Shearer, Christopher J / Stanley, Adrian J / Stuart, Robert C

    Surgical endoscopy

    2010  Volume 25, Issue 2, Page(s) 543–548

    Abstract: Background: Endoscopic mucosal resection (EMR) of early gastric and esophageal tumors is effective and avoids the morbidity and mortality of surgery. We report the long-term results of a consecutive series of 93 endoscopic resections, during a 7-year ... ...

    Abstract Background: Endoscopic mucosal resection (EMR) of early gastric and esophageal tumors is effective and avoids the morbidity and mortality of surgery. We report the long-term results of a consecutive series of 93 endoscopic resections, during a 7-year period, in a U.K. population.
    Methods: Eighty-eight patients with 93 lesions were included. EMR was performed for 64 and 29 malignant and benign lesions, respectively. Patients with malignant disease were subgrouped into "high risk" or "low risk" for recurrence.
    Results: Of the 35 lesions in the low-risk group, local control was achieved in 31; 29 after 1 EMR session. Two had residual invasive carcinoma, one had treatment ceased due to pancreatic cancer, and one patient did not attend follow-up. Of the 29 lesions in the high-risk group, local control was achieved in 15; 13 after 1 EMR session. Median follow-up was 53 months. Cancer specific survival for the 45 invasive cancers (T1m and T1sm) was 93%; three patients died from their disease.
    Conclusions: This study has shown for the first time in a U.K. population that EMR is effective in controlling disease in patients with local high grade dysplasia (HGD) and early invasive carcinoma, with no mortality and low morbidity.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Cohort Studies ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagogastric Junction/pathology ; Esophagogastric Junction/surgery ; Esophagoscopy/adverse effects ; Esophagoscopy/methods ; Female ; Follow-Up Studies ; Gastric Mucosa/pathology ; Gastric Mucosa/surgery ; Gastroscopy/adverse effects ; Gastroscopy/methods ; Humans ; Male ; Middle Aged ; Mucous Membrane/pathology ; Mucous Membrane/surgery ; Neoplasm Recurrence, Local/mortality ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/surgery ; Neoplasm Staging ; Postoperative Complications/mortality ; Postoperative Complications/physiopathology ; Retrospective Studies ; Risk Assessment ; Sex Factors ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Survival Analysis ; Time Factors ; Treatment Outcome ; United Kingdom
    Language English
    Publishing date 2010-07-10
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-010-1213-9
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    Zs.A 2214: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Exhaled ethane concentration in patients with cancer of the upper gastrointestinal tract - a proof of concept study.

    Abela, Jo Etienne / Skeldon, Kenneth D / Stuart, Robert C / Padgett, Miles J

    Bioscience trends

    2009  Volume 3, Issue 3, Page(s) 110–114

    Abstract: There has been growing interest in the measurement of breath ethane as an optimal non-invasive marker of oxidative stress. High concentrations of various breath alkanes including ethane have been reported in a number of malignancies. Our aim was to ... ...

    Abstract There has been growing interest in the measurement of breath ethane as an optimal non-invasive marker of oxidative stress. High concentrations of various breath alkanes including ethane have been reported in a number of malignancies. Our aim was to investigate the use of novel laser spectroscopy for rapid reporting of exhaled ethane and to determine whether breath ethane concentration is related to a diagnosis of upper gastrointestinal malignancy. Two groups of patients were recruited. Group A (n = 20) had a histo-pathological diagnosis of either esophageal or gastric malignancy. Group B (n = 10) was made up of healthy controls. Breath samples were collected from these subjects and the ethane concentration in these samples was subsequently measured to an accuracy of 0.2 parts per billion, ppb. Group A patients had a corrected exhaled breath ethane concentration of 2.3 +/- 0.8 (mean +/- SEM) ppb. Group B patients registered a mean of 3.1 +/- 0.5 ppb. There was no statistically significant difference between the two groups (p = 0.39). In conclusion, concentrations of ethane in collected breath samples were not significantly elevated in upper gastrointestinal malignancy. The laser spectroscopy system provided a reliable and rapid turnaround for breath sample analysis.
    MeSH term(s) Biomarkers, Tumor/analysis ; Breath Tests/methods ; Ethane/analysis ; Gastrointestinal Neoplasms/diagnosis ; Gastrointestinal Neoplasms/metabolism ; Humans ; Lasers ; Spectrum Analysis/methods ; Upper Gastrointestinal Tract/metabolism
    Chemical Substances Biomarkers, Tumor ; Ethane (L99N5N533T)
    Language English
    Publishing date 2009-06
    Publishing country Japan
    Document type Comparative Study ; Journal Article
    ZDB-ID 2543899-2
    ISSN 1881-7823 ; 1881-7815
    ISSN (online) 1881-7823
    ISSN 1881-7815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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