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  1. Article ; Online: Colonialism Revisited

    Dr. Muthanna Mohammed Sultan

    الأستاذ, Vol 224, Iss

    Reading in Selected Poems of the Nineteenth Century

    2018  Volume 1

    Abstract: This paper will try to discover and discuss the colonial contentsof some of the nineteenth-century British poets. At that time, the colonial ideology and impetus were increasingly elevated and demanded as the British Empire notably expanded and ... ...

    Abstract This paper will try to discover and discuss the colonial contentsof some of the nineteenth-century British poets. At that time, the colonial ideology and impetus were increasingly elevated and demanded as the British Empire notably expanded and significantly flourished. Colonialism was among the main aspects in the British political and social life. Literary figures and scholars dealt with thisnewly-born phenomenon differently; some welcomed and adhered it, while others showed some doubts and suspicion. There was no unified thread about the colonial project the Europeans held. Did exist there a kind of consensus? Or was there a sense of ambivalence about it? This paper is going to address these issues and attempt to reach at some plausible answers and results. To do this, the paper will analyze a group of poems by William Blake, Samuel Taylor Coleridge, Alfred, Lord Tennyson, and Rudyard Kipling.
    Keywords Colonialism ; nineteenth-century British poets ; William Blake ; Social sciences (General) ; H1-99
    Subject code 950
    Language Arabic
    Publishing date 2018-03-01T00:00:00Z
    Publisher Collage of Education Ibn Rushd / University of Baghdad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Integration of dynamic growth modeling and hydrodynamics in an internal‐loop split photobioreactor

    Sabri, Laith S / Ojha, Aastha / Sultan, Abbas J / Aldahhan, Muthanna H

    Journal of chemical technology and biotechnology. 2022 May, v. 97, no. 5

    2022  

    Abstract: In this study, new high‐quality experimental data for culturing green microalgae Scenedesmus in tubular and cylindrical split airlift photobioreactors were obtained under different operating conditions. The obtained experimental data of culturing ... ...

    Abstract In this study, new high‐quality experimental data for culturing green microalgae Scenedesmus in tubular and cylindrical split airlift photobioreactors were obtained under different operating conditions. The obtained experimental data of culturing microalgae Scenedesmus in a tubular photobioreactor were used for determining the kinetic parameters of the photosynthetic reaction. On the other hand, the culturing of green microalgae in a split airlift photobioreactor was used to measure the microalgae cell trajectory using an advanced radioactive particle tracking (RPT) technique. The obtained results in terms of kinetic parameters of the photosynthetic reaction and microalgae cell trajectory were integrated for the first time to obtain the three‐state dynamic growth model. This integration between dynamic growth and cell trajectories will provide a direct and comprehensive tool for photobioreactor analysis, which is essential for proper and efficient reactor design and scale‐up for large‐scale biomass production. © 2021 Society of Chemical Industry (SCI).
    Keywords Scenedesmus ; biomass production ; growth models ; hydrodynamics ; microalgae ; photobioreactors ; photosynthesis
    Language English
    Dates of publication 2022-05
    Size p. 1112-1127.
    Publishing place John Wiley & Sons, Ltd.
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 1479465-2
    ISSN 1097-4660 ; 0268-2575
    ISSN (online) 1097-4660
    ISSN 0268-2575
    DOI 10.1002/jctb.6996
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Administration of Δ9-Tetrahydrocannabinol (THC) Post-Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity.

    Mohammed, Amira / Alghetaa, Hasan / Sultan, Muthanna / Singh, Narendra P / Nagarkatti, Prakash / Nagarkatti, Mitzi

    Frontiers in pharmacology

    2020  Volume 11, Page(s) 893

    Abstract: Acute Respiratory Distress Syndrome (ARDS) is a life-threatening complication that can ensue ... ...

    Abstract Acute Respiratory Distress Syndrome (ARDS) is a life-threatening complication that can ensue following
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.00893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome by Downregulating miRNA that Target Inflammatory Pathways.

    Sultan, Muthanna / Alghetaa, Hasan / Mohammed, Amirah / Abdulla, Osama A / Wisniewski, Paul J / Singh, Narendra / Nagarkatti, Prakash / Nagarkatti, Mitzi

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 644281

    Abstract: Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, ...

    Abstract Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, anandamide (AEA), on ARDS induced in the mouse by
    Language English
    Publishing date 2021-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.644281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Detailed Hydrodynamic Study of the Split-Plate Airlift Reactor by Using Non-Invasive Gamma-Ray Techniques

    Laith S. Sabri / Abbas J. Sultan / Hasan Shakir Majdi / Shadha K. Jebur / Muthanna H. Al-Dahhan

    ChemEngineering, Vol 6, Iss 18, p

    2022  Volume 18

    Abstract: This study focused on detailed investigations of selected local hydrodynamics in split airlift reactor by using an unconventional measurements facility: computed tomography (CT) and radioactive particle tracking (RPT). The local distribution in a cross- ... ...

    Abstract This study focused on detailed investigations of selected local hydrodynamics in split airlift reactor by using an unconventional measurements facility: computed tomography (CT) and radioactive particle tracking (RPT). The local distribution in a cross-sectional manner with its radial’s profiles for gas holdup, liquid velocity flow field, shear stresses, and turbulent kinetic energy were studied under various gas velocity 1, 2 and 3 cm/s with various six axial level z = 12, 20, 40, 60, 90 and 112 cm. The distribution in gas–liquid phases in the whole split reactor column, the riser and downcomer sides, including their behavior at the top and bottom sections of the split plate was also described. The outcomes of this study displayed an exemplary gas–liquid phases dispersion approximately in all reactor’s zones and had large magnitude over the ring of the sparger as well as upper the split plate. Furthermore, the outcomes pointed out that the distribution of this flow may significantly impacts the performance of the split reactor, which may have essential influence on its performance particularly for microorganisms culturing applications. These outcomes are dependable as benchmark information to validate computational fluid dynamics (CFD) simulations and other models.
    Keywords split-plate airlift reactor ; hydrodynamics parameters ; non-invasive gamma-ray techniques ; Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Study of Gas Holdup Distribution in Cylindrical Split Airlift Reactor by Using Gamma-Ray Densitometry (GRD)

    Abbas J. Sultan / Laith S. Sabri / Hasan Shakir Majdi / Shadha K. Jebur / Muthanna H. Al-Dahhan

    Processes, Vol 10, Iss 910, p

    2022  Volume 910

    Abstract: The local gas holdup details and behaviors in the cylindrical split airlift column by using an unconventional gamma-ray densitometry (GRD) measurement in non-invasive manner technique was investigated for the first time in this work for such kind of ... ...

    Abstract The local gas holdup details and behaviors in the cylindrical split airlift column by using an unconventional gamma-ray densitometry (GRD) measurement in non-invasive manner technique was investigated for the first time in this work for such kind of airlift column. With different gas velocities, 1, 2, and 3 cm/s, at three various axial planes (different levels) in z = 3, 60, and 110 cm were studied for local distribution in radial gas holdup profiles. The distribution in gas–liquid phases (air-water system) in the entire split reactor column, in the rising and descending sides, including their behavior in the upper and lower zones of the split plate, were investigated as well. The results of this study showed that approximately all reactor zones had exemplary gas–liquid phases and that there was a large magnitude over both the dividing ring and the top sections. The results further indicated that the distribution of which flow variable in the implementation of the cylindrical split reactor can have an important impact on its behavior, especially for cultivating applications of microorganisms. These data can be used as benchmarks results for CFD simulations and validation.
    Keywords gas holdup ; cylindrical airlift reactor ; GRD technique ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Aggression in August Wilson’s King Hedley II

    Asma’a Mohannad Saad / Asst. Prof. (Dr) Muthanna Mohammad Sultan

    الأستاذ, Vol 58, Iss

    2019  Volume 4

    Abstract: The need for investigating the stereotypical image of the African American males as aggressive, criminal individuals brings this research to address this sensitive issue. But the stereotypes of the African American have drawn the attention of many black ... ...

    Abstract The need for investigating the stereotypical image of the African American males as aggressive, criminal individuals brings this research to address this sensitive issue. But the stereotypes of the African American have drawn the attention of many black writers and psychiatrists who tried to dismantle these images by revealing the social, psychological, and socioeconomic factors which contribute in this phenomenon. This paper highlights the reasons that drive the black males to adopt aggression through analyzing August Wilson’s King Hedley II (1999). In this play, Wilson portrays the widely spread aggression and its negative consequences. He also goes a step further and suggests a solution that the paper questions its validity.
    Keywords Aggression ; Frantz Fanon ; hegemony ; King Hedley II ; Social sciences (General) ; H1-99
    Language Arabic
    Publishing date 2019-12-01T00:00:00Z
    Publisher Collage of Education Ibn Rushd / University of Baghdad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota.

    Abdulla, Osama A / Neamah, Wurood / Sultan, Muthanna / Alghetaa, Hasan K / Singh, Narendra / Busbee, Philip Brandon / Nagarkatti, Mitzi / Nagarkatti, Prakash

    Frontiers in immunology

    2021  Volume 12, Page(s) 684727

    Abstract: Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates T cell function. The aim of this study was to investigate the effects of AhR ligands, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), and 6-Formylindolo[3,2-b]carbazole ...

    Abstract Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates T cell function. The aim of this study was to investigate the effects of AhR ligands, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), and 6-Formylindolo[3,2-b]carbazole (FICZ), on gut-associated microbiota and T cell responses during delayed-type hypersensitivity (DTH) reaction induced by methylated bovine serum albumin (mBSA) in a mouse model. Mice with DTH showed significant changes in gut microbiota including an increased abundance of
    MeSH term(s) Animals ; Basic Helix-Loop-Helix Transcription Factors/agonists ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Butyric Acid/pharmacology ; Carbazoles/toxicity ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Gastrointestinal Microbiome/drug effects ; Hypersensitivity, Delayed/genetics ; Hypersensitivity, Delayed/immunology ; Hypersensitivity, Delayed/metabolism ; Hypersensitivity, Delayed/prevention & control ; Ligands ; Mice ; Mice, Inbred C57BL ; Polychlorinated Dibenzodioxins/toxicity ; Receptors, Aryl Hydrocarbon/agonists ; Receptors, Aryl Hydrocarbon/metabolism ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Th17 Cells/drug effects ; Th17 Cells/immunology ; Th17 Cells/metabolism
    Chemical Substances 6-formylindolo(3,2-b)carbazole ; AHR protein, human ; Basic Helix-Loop-Helix Transcription Factors ; Carbazoles ; Cytokines ; Ligands ; Polychlorinated Dibenzodioxins ; Receptors, Aryl Hydrocarbon ; Butyric Acid (107-92-6)
    Language English
    Publishing date 2021-06-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.684727
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: AhR Ligands Differentially Regulate miRNA-132 Which Targets HMGB1 and to Control the Differentiation of Tregs and Th-17 Cells During Delayed-Type Hypersensitivity Response.

    Abdulla, Osama A / Neamah, Wurood / Sultan, Muthanna / Chatterjee, Saurabh / Singh, Narendra / Nagarkatti, Mitzi / Nagarkatti, Prakash

    Frontiers in immunology

    2021  Volume 12, Page(s) 635903

    Abstract: Aryl hydrocarbon receptor (AhR), is a transcription factor and an environmental sensor that has been shown to regulate T cell differentiation. Interestingly, AhR ligands exert varying effects from suppression to exacerbation of inflammation through ... ...

    Abstract Aryl hydrocarbon receptor (AhR), is a transcription factor and an environmental sensor that has been shown to regulate T cell differentiation. Interestingly, AhR ligands exert varying effects from suppression to exacerbation of inflammation through induction of Tregs and Th-17 cells, respectively. In the current study, we investigated whether the differential effects of AhR ligands on T cell differentiation are mediated by miRNA during delayed-type hypersensitivity (DTH) reaction against methylated Bovine Serum Albumin (mBSA). Treatment of C57BL/6 mice with TCDD attenuated mBSA-mediated DTH response, induced Tregs, decreased Th-17 cells, and caused upregulation of miRNA-132. TCDD caused an increase in several Treg subsets including inducible peripheral, natural thymic, and Th3 cells. Also, TCDD increased TGF-β and Foxp3 expression. In contrast, treating mice with FICZ exacerbated the DTH response, induced inflammatory Th17 cells, induced IL-17, and RORγ. Analysis of miRNA profiles from draining lymph nodes showed that miR-132 was upregulated in the TCDD group and downregulated in the FICZ group. Transfection studies revealed that miRNA-132 targeted High Mobility Group Box 1 (HMGB1). Downregulation of HMGB1 caused an increase in FoxP3+ Treg differentiation and suppression of Th-17 cells while upregulation of HMGB1 caused opposite effects. Moreover, TCDD was less effective in suppressing DTH response and induction of Tregs in mice that were deficient in miR-132. In summary, this study demonstrates that TCDD and FICZ have divergent effects on DTH response and T cell differentiation, which is mediated through, at least in part, regulation of miRNA-132 that targets HMGB1.
    MeSH term(s) Animals ; Basic Helix-Loop-Helix Transcription Factors/agonists ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Carbazoles/toxicity ; Cell Differentiation/drug effects ; Cells, Cultured ; Cytokines/genetics ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; HMGB1 Protein/genetics ; HMGB1 Protein/metabolism ; Hypersensitivity, Delayed/genetics ; Hypersensitivity, Delayed/immunology ; Hypersensitivity, Delayed/metabolism ; Hypersensitivity, Delayed/prevention & control ; Ligands ; Mice, Inbred C57BL ; Mice, Knockout ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Phenotype ; Polychlorinated Dibenzodioxins/toxicity ; Receptors, Aryl Hydrocarbon/agonists ; Receptors, Aryl Hydrocarbon/metabolism ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Th17 Cells/drug effects ; Th17 Cells/immunology ; Th17 Cells/metabolism ; Mice
    Chemical Substances 6-formylindolo(3,2-b)carbazole ; Ahr protein, mouse ; Basic Helix-Loop-Helix Transcription Factors ; Carbazoles ; Cytokines ; Forkhead Transcription Factors ; Foxp3 protein, mouse ; HMGB1 Protein ; HMGB1 protein, mouse ; Ligands ; MIRN132 microRNA, mouse ; MicroRNAs ; Polychlorinated Dibenzodioxins ; Receptors, Aryl Hydrocarbon
    Language English
    Publishing date 2021-02-19
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.635903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome through Modulation of Microbiome in the Gut-Lung Axis

    Muthanna Sultan / Kiesha Wilson / Osama A. Abdulla / Philip Brandon Busbee / Alina Hall / Taylor Carter / Narendra Singh / Saurabh Chatterjee / Prakash Nagarkatti / Mitzi Nagarkatti

    Cells, Vol 10, Iss 3305, p

    2021  Volume 3305

    Abstract: Acute respiratory distress syndrome (ARDS) is a serious lung condition characterized by severe hypoxemia leading to limitations of oxygen needed for lung function. In this study, we investigated the effect of anandamide (AEA), an endogenous cannabinoid, ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is a serious lung condition characterized by severe hypoxemia leading to limitations of oxygen needed for lung function. In this study, we investigated the effect of anandamide (AEA), an endogenous cannabinoid, on Staphylococcal enterotoxin B (SEB)-mediated ARDS in female mice. Single-cell RNA sequencing data showed that the lung epithelial cells from AEA-treated mice showed increased levels of antimicrobial peptides (AMPs) and tight junction proteins. MiSeq sequencing data on 16S RNA and LEfSe analysis demonstrated that SEB caused significant alterations in the microbiota, with increases in pathogenic bacteria in both the lungs and the gut, while treatment with AEA reversed this effect and induced beneficial bacteria. AEA treatment suppressed inflammation both in the lungs as well as gut-associated mesenteric lymph nodes (MLNs). AEA triggered several bacterial species that produced increased levels of short-chain fatty acids (SCFAs), including butyrate. Furthermore, administration of butyrate alone could attenuate SEB-mediated ARDS. Taken together, our data indicate that AEA treatment attenuates SEB-mediated ARDS by suppressing inflammation and preventing dysbiosis, both in the lungs and the gut, through the induction of AMPs, tight junction proteins, and SCFAs that stabilize the gut-lung microbial axis driving immune homeostasis.
    Keywords acute respiratory distress syndrome (ARDS) ; Staphylococcus enterotoxin B (SEB) ; anandamide (AEA) ; COVID-19 ; microbiome ; MiSeq sequencing ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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