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  1. Book ; Online ; E-Book: Polycystic ovary syndrome

    Diamanti-Kandarakis, Evanthia

    challenging issues in the modern era of individualized medicine

    2022  

    Author's details edited by Evanthia Diamanti-Kandarakis
    Language English
    Size 1 Online-Ressource (xvi, 334 Seiten), Illustrationen, Diagramme
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021214252
    ISBN 978-0-12-823046-6 ; 9780128230459 ; 0-12-823046-0 ; 0128230452
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Environmental endocrinology and endocrine disruptors

    Pivonello, Rosario / Diamanti-Kandarakis, Evanthia

    endocrine and endocrine-targeted actions and related human diseases

    (Endocrinology ; Springer reference nature)

    2023  

    Abstract: This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. ...

    Author's details Rosario Pivonello, Evanthia Diamanti-Kandarakis editors
    Series title Endocrinology
    Springer reference nature
    Abstract This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to ‘living editions’ that are constantly updated using a dynamic peer-review publishing process.
    Keywords Internal medicine
    Language English
    Size 1 Online-Ressource (xxli, 520 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030017028
    ISBN 978-3-030-39044-0 ; 9783030390433 ; 3-030-39044-6 ; 3030390438
    DOI 10.1007/978-3-030-39044-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Contemporary Aspects of Endocrinology

    Diamanti-Kandarakis, Evanthia

    2011  

    Keywords Endocrinology
    Size 1 electronic resource (480 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049932
    ISBN 9789535165934 ; 9535165933
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: Endocrine disruptors and puberty

    Diamanti-Kandarakis, Evanthia / Gore, Andrea C.

    (Contemporary endocrinology)

    2012  

    Author's details Evanthia Diamanti-Kandarakis ; Andrea C. Gore, ed
    Series title Contemporary endocrinology
    Language English
    Size XVII, 378 S. : Ill., 24 cm
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017088313
    ISBN 978-1-60761-560-6 ; 1-60761-560-6 ; 9781607615613 ; 1607615614
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 97 order for loan Magazin

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  5. Book: Insulin resistance and polycystic ovarian syndrome

    Diamanti-Kandarakis, Evanthia

    pathogenesis, evaluatioin, and treatment

    2007  

    Author's details ed. by John E. Nestler
    Keywords Polycystic Ovary Syndrome ; Insulin Resistance ; Metabolic Syndrome
    Language English
    Size XVIII, 487 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT014785405
    ISBN 978-1-58829-763-1 ; 1-58829-763-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 1317 order for loan Magazin

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  6. Book ; Online: Insulin Resistance and Polycystic Ovarian Syndrome

    Diamanti-Kandarakis, Evanthia / Nestler, John E. / Panidis, Dimitrios / Pasquali, Renato

    Pathogenesis, Evaluation, and Treatment

    2007  

    Author's details edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali
    Keywords Diabetes ; Endocrinology ; Internal medicine ; Medicine ; Obstetrics
    Language English
    Publisher Humana Press
    Publishing place Totowa, NJ
    Document type Book ; Online
    HBZ-ID HT018392217
    ISBN 978-1-588-29763-1 ; 978-1-597-45310-3 ; 1-588-29763-2 ; 1-597-45310-2
    DOI 10.1007/978-1-59745-310-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  7. Article ; Online: Preface.

    Diamanti-Kandarakis, Evanthia

    Reviews in endocrine & metabolic disorders

    2015  Volume 16, Issue 4, Page(s) 271

    MeSH term(s) Ecosystem ; Endocrine Disruptors ; Environment ; Humans
    Chemical Substances Endocrine Disruptors
    Language English
    Publishing date 2015-12
    Publishing country Germany
    Document type Introductory Journal Article
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-016-9343-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6069: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: The role of stress in PCOS.

    Papalou, Olga / Diamanti-Kandarakis, Evanthia

    Expert review of endocrinology & metabolism

    2017  Volume 12, Issue 1, Page(s) 87–95

    Abstract: Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting a remarkable proportion of premenopausal women. Different studies have shown that stress is widely encountered in women with PCOS. Areas covered: As PCOS is a ... ...

    Abstract Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting a remarkable proportion of premenopausal women. Different studies have shown that stress is widely encountered in women with PCOS. Areas covered: As PCOS is a multifaceted disorder, 'stress' incorporates different translations. We performed a literature review, focusing on the most recent data, regarding the multipotent role of stress in the syndrome. Expert commentary: Stress is believed to be an important component of PCOS. It encompasses different definitions that are all equivalent, like metabolic, inflammatory, oxidative and emotional stress. However, the type of stress that distinguishes PCOS is metabolic stress. It becomes evident early in life and constitutes the pathophysiological heart of the syndrome. Metabolic stress along with the other types of stress are the progenitors of severe long-term health implications, which exacerbate further the reproductive, metabolic and psychological derangements of the syndrome, leading to an endless cycle of chronic illness.
    Language English
    Publishing date 2017-01
    Publishing country England
    Document type Journal Article
    ISSN 1744-8417
    ISSN (online) 1744-8417
    DOI 10.1080/17446651.2017.1266250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Implications and Future Perspectives of AGEs in PCOS Pathophysiology.

    Merhi, Zaher / Kandaraki, Eleni A / Diamanti-Kandarakis, Evanthia

    Trends in endocrinology and metabolism: TEM

    2019  Volume 30, Issue 3, Page(s) 150–162

    Abstract: Human, animal, and in vitro studies provide evidence that advanced glycation end-products (AGEs) may contribute to the pathogenesis of polycystic ovary syndrome (PCOS) and its metabolic and reproductive consequences. AGEs are able to induce, via ... ...

    Abstract Human, animal, and in vitro studies provide evidence that advanced glycation end-products (AGEs) may contribute to the pathogenesis of polycystic ovary syndrome (PCOS) and its metabolic and reproductive consequences. AGEs are able to induce, via activation of key intracellular signaling pathways, the generation of oxidative stress and proinflammatory cytokines, thus contributing to the adverse health impact of PCOS. This review presents the implications of AGEs in several disease pathophysiologies, including PCOS, as well as the cellular and systemic effects of AGEs on insulin resistance (IR), hyperandrogenemia, endoplasmic reticulum (ER) stress, hypoxia, and ovarian function. The gaps in our knowledge will serve as launching pad for future developments ranging from dietary and lifestyle changes to pharmaceutical interventions aiming at potential applications in women with PCOS.
    MeSH term(s) Animals ; Female ; Glycation End Products, Advanced/metabolism ; Humans ; Insulin Resistance/physiology ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/physiopathology ; Receptor for Advanced Glycation End Products/metabolism
    Chemical Substances Glycation End Products, Advanced ; Receptor for Advanced Glycation End Products
    Language English
    Publishing date 2019-02-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1042384-9
    ISSN 1879-3061 ; 1043-2760
    ISSN (online) 1879-3061
    ISSN 1043-2760
    DOI 10.1016/j.tem.2019.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2999: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: The Role of Androgen Excess on Insulin Sensitivity in Women.

    Diamanti-Kandarakis, Evanthia / Papalou, Olga / Kandaraki, Eleni A

    Frontiers of hormone research

    2019  Volume 53, Page(s) 50–64

    Abstract: Sex steroids, except for their primary reproductive role, exert key effects on metabolic target tissues. Androgen receptors have been detected in various tissues, participating in both central and peripheral regulation of metabolism and insulin action. ... ...

    Abstract Sex steroids, except for their primary reproductive role, exert key effects on metabolic target tissues. Androgen receptors have been detected in various tissues, participating in both central and peripheral regulation of metabolism and insulin action. The physiological role of androgens in regulating multiple aspects of female insulin signaling and energy metabolism becomes evident early in utero, thus programming how insulin-targeted tissues will behave in later life. Across lifespan, distinct effects of androgens in all insulin-targeted tissues are controlled by their circulating serum levels, within a narrow window, outside of which disturbances in metabolism are observed. Thus, androgen excess in women, as documented in those with polycystic ovary syndrome, can adversely affect insulin sensitivity, promoting visceral adiposity, adipose tissue dysfunction, and, ultimately, insulin resistance.
    MeSH term(s) Adiposity ; Androgens/blood ; Androgens/metabolism ; Female ; Humans ; Hyperandrogenism/blood ; Hyperandrogenism/metabolism ; Insulin/blood ; Insulin/metabolism ; Insulin Resistance ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/metabolism
    Chemical Substances Androgens ; Insulin
    Language English
    Publishing date 2019-09-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1662-3762 ; 0301-3073
    ISSN (online) 1662-3762
    ISSN 0301-3073
    DOI 10.1159/000494902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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