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  1. Article ; Online: Shared Decision Making for Abdominal Aortic Aneurysm: Patients Want It But Are Not Getting It.

    Vijaykumar, Kalpana / Choke, Edward

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2023  Volume 65, Issue 6, Page(s) 850

    MeSH term(s) Humans ; Decision Making, Shared ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Decision Support Techniques
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2023.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Timing is Right Only When You Choose What is Right.

    Choke, Edward

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2018  Volume 56, Issue 6, Page(s) 783

    MeSH term(s) Carotid Artery, Common ; Constriction, Pathologic ; Humans ; Stents
    Language English
    Publishing date 2018-09-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2018.08.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Further Evidence for Regional Variation in Hospital Incidence of Abdominal Aortic Aneurysms: The German Data.

    Choke, Edward

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2018  Volume 55, Issue 6, Page(s) 860

    MeSH term(s) Aortic Aneurysm, Abdominal ; Data Analysis ; Germany ; Hospital Mortality ; Humans ; Incidence
    Language English
    Publishing date 2018-04-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2018.03.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Symptomatic Isolated Mesenteric Artery Dissection: Insights from a Conservative Approach.

    Choke, Edward / Aw, Darius Kang Lie

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2022  

    Language English
    Publishing date 2022-09-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2022.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice.

    Choke, Edward / Cockerill, Gillian W / Dawson, Joseph / Howe, Franklyn / Wilson, William R W / Loftus, Ian M / Thompson, Matthew M

    Journal of vascular surgery

    2010  Volume 52, Issue 1, Page(s) 159–166.e1

    Abstract: ... on experimental aneurysms.: Methods: Apolipoprotein E-deficient (apoE(-/-)) mice were assigned to one of four ...

    Abstract Objective: Abdominal aortic aneurysm (AAA) development is associated with increased angiogenesis and overexpression of vascular endothelial growth factor (VEGF). Inhibition of angiogenesis results in attenuation of experimental aneurysms. This study investigated the effects of recombinant human (rh)VEGF on experimental aneurysms.
    Methods: Apolipoprotein E-deficient (apoE(-/-)) mice were assigned to one of four groups: (1) normal saline infusion (sham), (2) angiotensin-II (AngII) infusion, (3) AngII infusion plus 100 microg daily rhVEGF for 14 days (AngII+14dVEGF), or (4) AngII infusion plus 100 microg daily rhVEGF for 21 days (AngII+21dVEGF). Aortic maximum diameter and cross-sectional area were determined by magnetic resonance imaging and microscopy. All mice were sacrificed at day 28.
    Results: Aneurysms developed in all mice in the AngII+14dVEGF and AngII+21dVEGF groups by day 21 compared with 40% in the AngII group. Treatment with rhVEGF increased maximum aortic diameter (P < .002) and cross-sectional area of aneurysms (P < .005) at day 21. This effect was maintained at day 28 (P < .0005). Decreasing rhVEGF treatment from 21 to 14 days did not attenuate aneurysm formation. Treatment with rhVEGF upregulated matrix metalloproteinase 2 gene expression within the aortic wall (P < .0009).
    Conclusions: Treatment with rhVEGF intensified the formation of AngII-induced aneurysms. Further studies are needed to investigate if antiangiogenic therapy may be a valid medical therapy against aneurysm expansion or rupture.
    MeSH term(s) Angiotensin II/administration & dosage ; Animals ; Aorta, Abdominal/metabolism ; Aorta, Abdominal/pathology ; Aortic Aneurysm, Abdominal/chemically induced ; Aortic Aneurysm, Abdominal/genetics ; Aortic Aneurysm, Abdominal/metabolism ; Aortic Aneurysm, Abdominal/pathology ; Apolipoproteins E/deficiency ; Apolipoproteins E/genetics ; Body Weight ; Dilatation, Pathologic ; Disease Models, Animal ; Disease Progression ; Gene Expression Regulation, Enzymologic ; Humans ; Infusion Pumps, Implantable ; Injections, Intraperitoneal ; Magnetic Resonance Angiography ; Male ; Matrix Metalloproteinase 2/genetics ; Mice ; Mice, Knockout ; Recombinant Proteins/administration & dosage ; Time Factors ; Vascular Endothelial Growth Factor A/administration & dosage
    Chemical Substances Apolipoproteins E ; Recombinant Proteins ; VEGFA protein, human ; Vascular Endothelial Growth Factor A ; Angiotensin II (11128-99-7) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; Mmp2 protein, mouse (EC 3.4.24.24)
    Language English
    Publishing date 2010-05-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2010.02.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Commentary on "Development of Collaterals to the Spinal Cord After Endovascular Stent Graft Repair of Thoracic Aneurysms".

    Choke, E

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2016  Volume 52, Issue 6, Page(s) 808

    Language English
    Publishing date 2016-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2016.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Commentary to "Outcome After Turndown for Elective Abdominal Aortic Aneurysm Surgery".

    Choke, Edward

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2017  Volume 54, Issue 5, Page(s) 587

    Language English
    Publishing date 2017-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2017.08.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Carotid Plaques - Should Looks Matter Too?

    Choke, Edward / Lee, Jia H

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2021  Volume 62, Issue 5, Page(s) 727

    MeSH term(s) Carotid Arteries ; Humans ; Plaque, Atherosclerotic
    Language English
    Publishing date 2021-09-21
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2021.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Commentary on 'Low post-operative mortality after surgery on patients with screening-detected abdominal aortic aneurysms: a Swedvasc registry study'.

    Choke, E

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2014  Volume 48, Issue 6, Page(s) 657–658

    MeSH term(s) Aortic Aneurysm, Abdominal/diagnosis ; Aortic Aneurysm, Abdominal/surgery ; Endovascular Procedures/mortality ; Humans ; Male ; Mass Screening/methods ; Patient Selection ; Postoperative Complications/mortality ; Vascular Surgical Procedures/mortality
    Language English
    Publishing date 2014-12
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2014.10.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Uncomplicated Type B Aortic Dissection: Complicated Choices.

    Choke, Edward / Verhoeven, Eric

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2020  Volume 60, Issue 2, Page(s) 201–202

    MeSH term(s) Aneurysm, Dissecting ; Aortic Aneurysm, Thoracic ; Australia ; Decision Making ; Humans ; New Zealand ; Surgeons ; Surveys and Questionnaires
    Language English
    Publishing date 2020-07-03
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2020.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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