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  1. Article ; Online: Why there is new hope for the care of chronic diseases in Africa.

    Moeti, Matshidiso / Mocumbi, Ana / Bukhman, Gene

    BMJ (Clinical research ed.)

    2023  Volume 383, Page(s) 2382

    MeSH term(s) Humans ; Africa/epidemiology ; Chronic Disease
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p2382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Universal health coverage for the poorest billion: justice and equity considerations - Authors' reply.

    Bukhman, Gene / Mocumbi, Ana

    Lancet (London, England)

    2021  Volume 397, Issue 10273, Page(s) 474

    MeSH term(s) Humans ; Poverty ; Social Justice ; Universal Health Insurance
    Language English
    Publishing date 2021-02-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)32389-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Heart failure in Africa: continuity or change?

    Bukhman, Gene

    Heart (British Cardiac Society)

    2014  Volume 100, Issue 16, Page(s) 1223–1224

    MeSH term(s) Anemia/epidemiology ; Atrial Fibrillation ; Diabetes Mellitus/epidemiology ; Female ; HIV Infections/epidemiology ; Heart Failure ; Humans ; Male ; Tuberculosis/epidemiology
    Language English
    Publishing date 2014-08
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2014-305936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The COVID-19 Pandemic: A Massive Threat for Those Living With Cardiovascular Disease Among the Poorest Billion.

    Klassen, Sheila L / Kwan, Gene F / Bukhman, Gene

    Circulation

    2020  Volume 142, Issue 20, Page(s) 1887–1889

    MeSH term(s) Africa South of the Sahara/epidemiology ; Asia, Southeastern/epidemiology ; Betacoronavirus/isolation & purification ; COVID-19 ; Cardiovascular Diseases/pathology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Delivery of Health Care ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Poverty ; Rural Population ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.047969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Models of care for sickle cell disease in low-income and lower-middle-income countries: a scoping review.

    Drown, Laura / Osei, Miriam / Thapa, Ada / Boudreaux, Chantelle / Archer, Natasha / Bukhman, Gene / Adler, Alma J

    The Lancet. Haematology

    2024  Volume 11, Issue 4, Page(s) e299–e308

    Abstract: Sickle cell disease has a growing global burden falling primarily on low-income countries (LICs) and lower-middle-income countries (LMICs) where comprehensive care is often insufficient, particularly in rural areas. Integrated care models might be ... ...

    Abstract Sickle cell disease has a growing global burden falling primarily on low-income countries (LICs) and lower-middle-income countries (LMICs) where comprehensive care is often insufficient, particularly in rural areas. Integrated care models might be beneficial for improving access to care in areas with human resource and infrastructure constraints. As part of the Centre for Integration Science's ongoing efforts to define, systematise, and implement integrated care delivery models for non-communicable diseases (NCDs), this Review explores models of care for sickle cell disease in LICs and LMICs. We identified 99 models from 136 studies, primarily done in tertiary, urban facilities in LMICs. Except for two models of integrated care for concurrent treatment of other conditions, sickle cell disease care was mostly provided in specialised clinics, which are low in number and accessibility. The scarcity of published evidence of models of care for sickle cell disease and integrated care in rural settings of LICs and LMICs shows a need to implement more integrated models to improve access, particularly in rural areas. PEN-Plus, a model of decentralised, integrated care for severe chronic non-communicable diseases, provides an approach to service integration that could fill gaps in access to comprehensive sickle cell disease care in LICs and LMICs.
    MeSH term(s) Humans ; Developing Countries ; Noncommunicable Diseases/therapy ; Poverty ; Delivery of Health Care, Integrated
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2352-3026
    ISSN (online) 2352-3026
    DOI 10.1016/S2352-3026(24)00007-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Non-communicable disease care in Sierra Leone: a mixed-methods study of the drivers and barriers to retention in care for hypertension.

    Dibba, Yusupha / Kachimanga, Chiyembekezo / Gassimu, Joseph / Kulinkina, Alexandra V / Bukhman, Gene / Gilbert, Hannah N / Adler, Alma J / Mukherjee, Joia S

    BMJ open

    2024  Volume 14, Issue 2, Page(s) e077326

    Abstract: Objective: To retrospectively analyse routinely collected data on the drivers and barriers to retention in chronic care for patients with hypertension in the Kono District of Sierra Leone.: Design: Convergent mixed-methods study.: Setting: Koidu ... ...

    Abstract Objective: To retrospectively analyse routinely collected data on the drivers and barriers to retention in chronic care for patients with hypertension in the Kono District of Sierra Leone.
    Design: Convergent mixed-methods study.
    Setting: Koidu Government Hospital, a secondary-level hospital in Kono District.
    Participants: We conducted a descriptive analysis of key variables for 1628 patients with hypertension attending the non-communicable disease (NCD) clinic between February 2018 and August 2019 and qualitative interviews with 21 patients and 7 staff to assess factors shaping patients' retention in care at the clinic.
    Outcomes: Three mutually exclusive outcomes were defined for the study period: adherence to the treatment protocol (attending >80% of scheduled visits); loss-to-follow-up (LTFU) (consecutive 6 months of missed appointments) and engaged in (but not fully adherent) with treatment (<80% attendance).
    Results: 57% of patients were adherent, 20% were engaged in treatment and 22% were LTFU. At enrolment, in the unadjusted variables, patients with higher systolic and diastolic blood pressures had better adherence than those with lower blood pressures (OR 1.005, 95% CI 1.002 to 1.009, p=0.004 and OR 1.008, 95% CI 1.004 to 1.012, p<0.001, respectively). After adjustment, there were 14% lower odds of adherence to appointments associated with a 1 month increase in duration in care (OR 0.862, 95% CI 0.801 to 0.927, p<0.001). Qualitative findings highlighted the following drivers for retention in care: high-quality education sessions, free medications and good interpersonal interactions. Challenges to seeking care included long wait times, transport costs and misunderstanding of the long-term requirement for hypertension care.
    Conclusion: Free medications, high-quality services and health education may be effective ways of helping NCD patients stay engaged in care. Facility and socioeconomic factors can pose challenges to retention in care.
    MeSH term(s) Humans ; Noncommunicable Diseases/therapy ; Retrospective Studies ; Sierra Leone ; Retention in Care ; Hypertension/therapy
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-077326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The origins of the 4 × 4 framework for noncommunicable disease at the World Health Organization.

    Schwartz, Leah N / Shaffer, Jonathan D / Bukhman, Gene

    SSM - population health

    2021  Volume 13, Page(s) 100731

    Abstract: This paper traces the history of noncommunicable disease public health research and programming at the World Health Organization. Specifically, it investigates the origins of the now pervasive 4 × 4 framework focusing on four sets of diseases ( ... ...

    Abstract This paper traces the history of noncommunicable disease public health research and programming at the World Health Organization. Specifically, it investigates the origins of the now pervasive 4 × 4 framework focusing on four sets of diseases (cardiovascular diseases, diabetes, chronic respiratory diseases, and cancers) caused by four behavioral risk factors (tobacco use, harmful use of alcohol, unhealthy diets, and physical inactivity). We have found that the 4 × 4 framework developed as a generalization from strategies to control epidemics of cardiovascular disease and stroke in high-income countries during the second half of the twentieth century. These strategies, which were narrowly focused on interventions to address behavioral "lifestyle" risk factors as well as pharmacotherapy for physiologic risk factors, were ultimately packaged as an integrated approach initially in high-income countries and subsequently extended to low- and middle-income countries, where they have failed to address much of the burden among very poor populations.
    Language English
    Publishing date 2021-01-11
    Publishing country England
    Document type Journal Article
    ISSN 2352-8273
    ISSN 2352-8273
    DOI 10.1016/j.ssmph.2021.100731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The origins of the 4 × 4 framework for noncommunicable disease at the World Health Organization

    Leah N. Schwartz / Jonathan D. Shaffer / Gene Bukhman

    SSM: Population Health, Vol 13, Iss , Pp 100731- (2021)

    2021  

    Abstract: This paper traces the history of noncommunicable disease public health research and programming at the World Health Organization. Specifically, it investigates the origins of the now pervasive 4 × 4 framework focusing on four sets of diseases ( ... ...

    Abstract This paper traces the history of noncommunicable disease public health research and programming at the World Health Organization. Specifically, it investigates the origins of the now pervasive 4 × 4 framework focusing on four sets of diseases (cardiovascular diseases, diabetes, chronic respiratory diseases, and cancers) caused by four behavioral risk factors (tobacco use, harmful use of alcohol, unhealthy diets, and physical inactivity). We have found that the 4 × 4 framework developed as a generalization from strategies to control epidemics of cardiovascular disease and stroke in high-income countries during the second half of the twentieth century. These strategies, which were narrowly focused on interventions to address behavioral “lifestyle” risk factors as well as pharmacotherapy for physiologic risk factors, were ultimately packaged as an integrated approach initially in high-income countries and subsequently extended to low- and middle-income countries, where they have failed to address much of the burden among very poor populations.
    Keywords Noncommunicable Diseases (NCDs) ; WHO ; 4 × 4 framework ; Global health ; Public aspects of medicine ; RA1-1270 ; Social sciences (General) ; H1-99
    Subject code 306
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The COVID-19 pandemic

    Klassen, Sheila L / Kwan, Gene F / Bukhman, Gene

    Circulation ; ISSN 0009-7322 1524-4539

    a massive threat for those living with cardiovascular disease among the poorest billion

    2020  

    Keywords Physiology (medical) ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    DOI 10.1161/circulationaha.120.047969
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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