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  1. Article: Successful treatment with ivabradine in a β-blocker-refractory patient with acute decompensated heart failure with reduced ejection fraction.

    Inoue, Tomoko / Matsunaga, Keiji / Kobayashi, Waki / Minamino, Tetsuo

    Clinical case reports

    2023  Volume 11, Issue 3, Page(s) e6890

    Abstract: Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF); however, it is not used for acute heart failure treatment. Negative inotropic effects (NIE) often limit the up-titration of β-blockers. Contrarily, ... ...

    Abstract Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF); however, it is not used for acute heart failure treatment. Negative inotropic effects (NIE) often limit the up-titration of β-blockers. Contrarily, ivabradine has no NIE, and enables β-blockers usage for treating patients with acute decompensated HFrEF.
    Language English
    Publishing date 2023-03-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Phenotypic homozygous familial hypercholesterolemia successfully treated with proprotein convertase subtilisin/kexin type 9 inhibitors.

    Tani, Ryosuke / Matsunaga, Keiji / Toda, Yuta / Inoue, Tomoko / Fu, Hai Ying / Minamino, Tetsuo

    Clinical case reports

    2024  Volume 12, Issue 2, Page(s) e8537

    Abstract: Recent data reveal phenotypic HoFH patients may be responsive to PCSK9 inhibitors, challenging prior assumptions. Genetic testing advancements now more accurately forecast patient responses to these therapies, improving treatment strategies. ...

    Abstract Recent data reveal phenotypic HoFH patients may be responsive to PCSK9 inhibitors, challenging prior assumptions. Genetic testing advancements now more accurately forecast patient responses to these therapies, improving treatment strategies.
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.8537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The impact of dietary fat type on lipid profiles in lean mass hyper-responder phenotype.

    Takemura, Yuma / Inoue, Tomoko / Matsunaga, Keiji / Tani, Ryosuke / Fu, Hai Ying / Minamino, Tetsuo

    Clinical case reports

    2024  Volume 12, Issue 2, Page(s) e8485

    Abstract: Key clinical message: Although the lean mass hyper-responder (LMHR) phenotype is well known, its diagnosis is impeded by the influence of fat type and intake on the lipid profile. Accordingly, a detailed assessment is warranted if LMHR is suspected.: ... ...

    Abstract Key clinical message: Although the lean mass hyper-responder (LMHR) phenotype is well known, its diagnosis is impeded by the influence of fat type and intake on the lipid profile. Accordingly, a detailed assessment is warranted if LMHR is suspected.
    Abstract: A 47-year-old man with suspected familial hypercholesterolemia presented with elevated triglyceride and low-density lipoprotein cholesterol levels. He had adhered to a ketogenic diet and was suspected of a lean mass hyper-responder phenotype; however, his lipid profile did not meet the definition. His lipid profile improved through dietary management without medication.
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.8485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Successful treatment with ivabradine in a β‐blocker‐refractory patient with acute decompensated heart failure with reduced ejection fraction

    Tomoko Inoue / Keiji Matsunaga / Waki Kobayashi / Tetsuo Minamino

    Clinical Case Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)

    2023  

    Abstract: Abstract Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF); however, it is not used for acute heart failure treatment. Negative inotropic effects (NIE) often limit the up‐titration of β‐blockers. ... ...

    Abstract Abstract Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF); however, it is not used for acute heart failure treatment. Negative inotropic effects (NIE) often limit the up‐titration of β‐blockers. Contrarily, ivabradine has no NIE, and enables β‐blockers usage for treating patients with acute decompensated HFrEF.
    Keywords acute decompensated heart failure ; cancer therapy‐related cardiac dysfunction ; inappropriate tachycardia ; ivabradine ; up‐titration ; β‐Blocker ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Diagnostic Performance of an Automated Blood Pressure Monitor With an Irregular Heartbeat Algorithm Designed to Detect Atrial Fibrillation.

    Ishihara, Yu / Ishizawa, Makoto / Noma, Takahisa / Ohara, Minako / Tani, Ryosuke / Kurashita, Genki / Toda, Yuta / Kobayashi, Waki / Minamino, Tetsuo

    Circulation reports

    2024  Volume 6, Issue 4, Page(s) 110–117

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-03-22
    Publishing country Japan
    Document type Journal Article
    ISSN 2434-0790
    ISSN (online) 2434-0790
    DOI 10.1253/circrep.CR-24-0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: d-allulose protects against diabetic nephropathy progression in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes.

    Niibo, Misato / Kanasaki, Akane / Iida, Tetsuo / Ohnishi, Keisuke / Ozaki, Taro / Akimitsu, Kazuya / Minamino, Tetsuo

    PloS one

    2022  Volume 17, Issue 1, Page(s) e0263300

    Abstract: d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty ( ... ...

    Abstract d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat model of type 2 diabetes mellitus. Drinking water with or without 3% d-allulose was administered to OLETF rats for 13 weeks. Long-Evans Tokushima Otsuka rats that received drinking water without d-allulose were used as non-diabetic control rats. d-allulose significantly attenuated the increase in blood glucose levels and progressive mesangial expansion in the glomerulus, which is regarded as a characteristic of diabetic nephropathy, in OLETF rats. d-allulose also attenuated the significant increases in renal IL-6 and tumor necrosis factor-α mRNA levels in OLETF rats, which is a proinflammatory parameter. Additionally, we showed that d-allulose suppresses mesangial matrix expansion, but its correlation with suppressing renal inflammation in OLETF rats should be investigated further. Collectively, our results support the hypothesis that d-allulose can prevent diabetic nephropathy in rats.
    MeSH term(s) Animals ; Blood Glucose/metabolism ; Body Weight ; Cytokines/genetics ; Cytokines/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/pathology ; Diabetes Mellitus, Type 2/urine ; Diabetic Nephropathies/blood ; Diabetic Nephropathies/drug therapy ; Diabetic Nephropathies/urine ; Disease Progression ; Drinking Behavior ; Fasting/blood ; Fasting/urine ; Feeding Behavior ; Fructose/pharmacology ; Fructose/therapeutic use ; Inflammation Mediators/metabolism ; Insulin/blood ; Kidney/drug effects ; Kidney/pathology ; Male ; Organ Size ; Protective Agents/pharmacology ; Protective Agents/therapeutic use ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Inbred OLETF ; Rats
    Chemical Substances Blood Glucose ; Cytokines ; Inflammation Mediators ; Insulin ; Protective Agents ; RNA, Messenger ; psicose (23140-52-5) ; Fructose (30237-26-4)
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0263300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Caution regarding induction of Type 1 Brugada electrocardiogram through drug testing followed by full-stomach conditions.

    Matsunaga, Keiji / Inoue, Tomoko / Ishihara, Yu / Minamino, Tetsuo

    European heart journal. Case reports

    2020  Volume 4, Issue 4, Page(s) 1–2

    Language English
    Publishing date 2020-07-09
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytaa154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  8. Article ; Online: d-allulose protects against diabetic nephropathy progression in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes.

    Misato Niibo / Akane Kanasaki / Tetsuo Iida / Keisuke Ohnishi / Taro Ozaki / Kazuya Akimitsu / Tetsuo Minamino

    PLoS ONE, Vol 17, Iss 1, p e

    2022  Volume 0263300

    Abstract: d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty ( ... ...

    Abstract d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat model of type 2 diabetes mellitus. Drinking water with or without 3% d-allulose was administered to OLETF rats for 13 weeks. Long-Evans Tokushima Otsuka rats that received drinking water without d-allulose were used as non-diabetic control rats. d-allulose significantly attenuated the increase in blood glucose levels and progressive mesangial expansion in the glomerulus, which is regarded as a characteristic of diabetic nephropathy, in OLETF rats. d-allulose also attenuated the significant increases in renal IL-6 and tumor necrosis factor-α mRNA levels in OLETF rats, which is a proinflammatory parameter. Additionally, we showed that d-allulose suppresses mesangial matrix expansion, but its correlation with suppressing renal inflammation in OLETF rats should be investigated further. Collectively, our results support the hypothesis that d-allulose can prevent diabetic nephropathy in rats.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  9. Article ; Online: d-allulose protects against diabetic nephropathy progression in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes

    Misato Niibo / Akane Kanasaki / Tetsuo Iida / Keisuke Ohnishi / Taro Ozaki / Kazuya Akimitsu / Tetsuo Minamino

    PLoS ONE, Vol 17, Iss

    2022  Volume 1

    Abstract: d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty ( ... ...

    Abstract d-allulose is a rare sugar that has been reported to possess anti-hyperglycemic effects. In the present study, we hypothesized that d-allulose is effective in attenuating the progression of diabetic nephropathy in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat model of type 2 diabetes mellitus. Drinking water with or without 3% d-allulose was administered to OLETF rats for 13 weeks. Long-Evans Tokushima Otsuka rats that received drinking water without d-allulose were used as non-diabetic control rats. d-allulose significantly attenuated the increase in blood glucose levels and progressive mesangial expansion in the glomerulus, which is regarded as a characteristic of diabetic nephropathy, in OLETF rats. d-allulose also attenuated the significant increases in renal IL-6 and tumor necrosis factor-α mRNA levels in OLETF rats, which is a proinflammatory parameter. Additionally, we showed that d-allulose suppresses mesangial matrix expansion, but its correlation with suppressing renal inflammation in OLETF rats should be investigated further. Collectively, our results support the hypothesis that d-allulose can prevent diabetic nephropathy in rats.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  10. Article: Paper-like bilateral sternocleidomastoid muscle atrophy may suggest the occurrence of sustained ventricular tachycardia.

    Matsunaga, Keiji / Miyake, Yuichi / Noma, Takahisa / Minamino, Tetsuo

    HeartRhythm case reports

    2019  Volume 6, Issue 1, Page(s) 48–49

    Language English
    Publishing date 2019-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2019.10.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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