LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 614

Search options

  1. Article ; Online: Bioactivities of thymol and p-cymene from the essential oil of Adenosma buchneroides against three stored-product insects.

    Xie, Qiao-Hui / Tian-Liang / Li, Bo-Ya / Yu, Jiao-Neng / Zheng, Yu / Du, Shu-Shan / Borjigidai, Almaz

    Environmental science and pollution research international

    2023  Volume 30, Issue 51, Page(s) 110841–110850

    Abstract: ... Subsequently, EO as well as its main constituents (thymol and p-cymene) were tested for their insecticidal ... and the booklouse (Liposcelis bostrychophila). The joint action of thymol and p-cymene produced ... compounds, thymol, and p-cymene both showed significant toxic activity against the target pests ...

    Abstract The adverse effects of relying solely on synthetic pesticides have become increasingly evident, leading many countries to explore alternatives sourced from plant-based green economies. Essential oil (EO) from stems and leaves of Adenosma buchneroides Bonati (A. buchneroides) was distilled by using hydrodistillation and subjected to gas chromatography-mass spectrometry (GC-MS) for component identification. Subsequently, EO as well as its main constituents (thymol and p-cymene) were tested for their insecticidal activity against the red flour beetle (Tribolium castaneum), the cigarette beetle (Lasioderma serricorne), and the booklouse (Liposcelis bostrychophila). The joint action of thymol and p-cymene produced an additive or synergistic effect. A. buchneroides essential oil (BHO) and the fixed ratio of the main compounds, thymol, and p-cymene both showed significant toxic activity against the target pests. This toxic effect is not simply the sum of individual effects, as it is influenced by various factors such as insect species and mode of action. These findings imply that the BHO and its phytoconstituents possess great potential to develop plant-derived biopesticides that will be safe for humans and the environment.
    MeSH term(s) Animals ; Humans ; Oils, Volatile/chemistry ; Thymol/pharmacology ; Insect Repellents/pharmacology ; Insecta ; Coleoptera ; Tribolium ; Insecticides/chemistry
    Chemical Substances Oils, Volatile ; Thymol (3J50XA376E) ; 4-cymene (1G1C8T1N7Q) ; Insect Repellents ; Insecticides
    Language English
    Publishing date 2023-10-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-30068-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Rapid Evaluation Method for Accuracy of Range Estimation of Pure Electric Vehicle Range Estimation Based on CLTC-P

    Dai Tianlu / Zhou Boya / Zhang Yanyi / Chen Guang / Liu Peng

    E3S Web of Conferences, Vol 235, p

    2021  Volume 01035

    Abstract: ... for estimating the accuracy of the range of pure electric vehicles based on CLTC-P, which is based on different ...

    Abstract Based on theoretical and experimental research, this paper constructs a rapid test method for estimating the accuracy of the range of pure electric vehicles based on CLTC-P, which is based on different environmental temperatures, air conditioning use, test scenarios, and high-speed operating conditions. The article further compares and analyzes a variety of mathematical statistical methods and selects certain coefficients to evaluate the accuracy of cruising range estimation, and proposes a general rapid test method and evaluation theory of cruising range estimation accuracy, which lays the foundation for establishing a unified assessment standard in industry, and promotes the development of the electric vehicle industry.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  3. Article ; Online: Autophagy and disease: new insights and challenges ahead.

    Boya, Patricia

    Molecular aspects of medicine

    2021  Volume 82, Page(s) 101047

    MeSH term(s) Autophagy ; Humans
    Language English
    Publishing date 2021-11-23
    Publishing country England
    Document type Editorial
    ZDB-ID 197640-0
    ISSN 1872-9452 ; 0098-2997
    ISSN (online) 1872-9452
    ISSN 0098-2997
    DOI 10.1016/j.mam.2021.101047
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Lipid dismantling of lens organelles for clear vision.

    Boya, Patricia

    Nature

    2021  Volume 592, Issue 7855, Page(s) 509–510

    MeSH term(s) Phospholipases ; Lens, Crystalline ; Visual Acuity ; Organelles ; Lipids
    Chemical Substances Phospholipases (EC 3.1.-) ; Lipids
    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type News ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-021-00888-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: High-mobility graphene on liquid p-block elements by ultra-low-loss CVD growth.

    Wang, Jiao / Zeng, Mengqi / Tan, Lifang / Dai, Boya / Deng, Yuan / Rümmeli, Mark / Xu, Haitao / Li, Zishen / Wang, Sheng / Peng, Lianmao / Eckert, Jürgen / Fu, Lei

    Scientific reports

    2013  Volume 3, Page(s) 2670

    Abstract: ... quality single-layer, single-crystalline graphene flakes and their continuous films over p-block elements ...

    Abstract The high-quality and low-cost of the graphene preparation method decide whether graphene is put into the applications finally. Enormous efforts have been devoted to understand and optimize the CVD process of graphene over various d-block transition metals (e.g. Cu, Ni and Pt). Here we report the growth of uniform high-quality single-layer, single-crystalline graphene flakes and their continuous films over p-block elements (e.g. Ga) liquid films using ambient-pressure chemical vapor deposition. The graphene shows high crystalline quality with electron mobility reaching levels as high as 7400 cm(2) V(-1) s(-1) under ambient conditions. Our employed growth strategy is ultra-low-loss. Only trace amounts of Ga are consumed in the production and transfer of the graphene and expensive film deposition or vacuum systems are not needed. We believe that our research will open up new territory in the field of graphene growth and thus promote its practical application.
    Language English
    Publishing date 2013-09-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep02670
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Aging STINGs: mitophagy at the crossroads of neuroinflammation.

    Jiménez-Loygorri, Juan Ignacio / Boya, Patricia

    Autophagy

    2024  , Page(s) 1–3

    Abstract: Loss of proteostasis and dysregulated mitochondrial function are part of the traditional hallmarks of aging, and in their last revision impaired macroautophagy and chronic inflammation are also included. Mitophagy is at the intersection of all these ... ...

    Abstract Loss of proteostasis and dysregulated mitochondrial function are part of the traditional hallmarks of aging, and in their last revision impaired macroautophagy and chronic inflammation are also included. Mitophagy is at the intersection of all these processes but whether it undergoes age-associated perturbations was not known. In our recent work, we performed a systematic and systemic analysis of mitolysosome levels in mice and found that, despite the already-known decrease in nonselective macroautophagy, mitophagy remains stable or increases upon aging in all tissues analyzed and is mediated by the PINK1-PRKN-dependent pathway. Further analyses revealed a concomitant increase in mtDNA leakage into the cytosol and activation of the CGAS-STING1 inflammation axis. Notably, both phenomena are also observed in primary fibroblasts from aged human donors. We hypothesized that mitophagy might be selectively upregulated during aging to improve mitochondrial fitness and reduce mtDNA-induced inflammation. Treatment with the mitophagy inducer urolithin A alleviates age-associated neurological decline, including improved synaptic connectivity, cognitive memory and visual function. Supporting our initial hypothesis, urolithin A reduces the levels of cytosolic mtDNA, CGAS-STING1 activation and neuroinflammation. Finally, using an
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2024.2322421
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Why autophagy is good for retinal ganglion cells?

    Boya, P

    Eye (London, England)

    2017  Volume 31, Issue 2, Page(s) 185–190

    Abstract: Autophagy is a catabolic pathway that promotes the degradation and recycling of cellular components. Proteins, lipids, and even whole organelles are engulfed in autophagosomes and delivered to the lysosome for elimination. In response to stress, ... ...

    Abstract Autophagy is a catabolic pathway that promotes the degradation and recycling of cellular components. Proteins, lipids, and even whole organelles are engulfed in autophagosomes and delivered to the lysosome for elimination. In response to stress, autophagy mediates the degradation of cell components, which are recycled to generate the nutrients and building blocks required to sustain cellular homeostasis. Moreover, it has an important role in cellular quality control, particularly in neurons, in which the total burden of altered proteins and damaged organelles cannot be reduced by redistribution to daughter cells through cell division. Autophagy occurs in all cells and tissues, and it is regulated by the Atg genes. The importance of this pathway has been recently recognized by the Nobel Prize in Physiology and Medicine award to Professor Yoshinori Ohsumi who was the discoverer of the first Atg genes in yeast in the 1990s. Research has only begun to examine the role of autophagy in the visual system. Both the retina and the eye are exposed to a variety of environmental insults and stressors, including genetic mutations and age-associated alterations that impair their function. Here, we review studies that have sought to explain autophagy's importance for retinal ganglion cells, and their implications for diseases like glaucoma and optic neuropathies.
    MeSH term(s) Aging/physiology ; Animals ; Autophagy/physiology ; Cell Death/physiology ; Eye Diseases/physiopathology ; Humans ; Retina/physiology ; Retinal Ganglion Cells/physiology
    Language English
    Publishing date 2017-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/eye.2016.278
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Cardiovascular Perceived Exertion and Blood Lactate Response afterBadminton Matches

    Manhal Nabeel Boya Boya

    دراسات وبحوث التربية الرياضية, Vol 31, Iss

    2021  Volume 2

    Abstract: ... match comparing to others with significant differences among them for both before F3, 15= 20.08, P=0.000 ... F3, 15= 14.80, P=0.000, and after the end of the matches F3, 15= 16.48, P=0.000. F3, 15= 13.71, P=0 ...

    Abstract Badminton is the fastest racket game with action of short duration and high intensity. Purpose: to measure and compare blood lactate concentration, PRE, heart rate and blood pressure before and after repeated badminton matches. Method: Six national ranked players (age = 22.6 ± 5.3 years; height = 172.5 ± 3.2 cm, weight = 66.1 ± 5.3 kg) played four badminton matches in raw with recovery period of 30 minutes in which Heart Rate, Blood pressure and RPE were measured before and immediately after the end ofeach match. Additionally, blood lactate concentration was measured before and after 5 min from the end of the match. Result: the study indicates that blood lactate concentration and RPE were higher in the fourth match comparing to others with significant differences among them for both before F3, 15= 20.08, P=0.000, F3, 15= 14.80, P=0.000, and after the end of the matches F3, 15= 16.48, P=0.000. F3, 15= 13.71, P=0.000, respectively. No significant differences for heart rate and blood pressure were found. Conclusion: the repetitive badminton matches exerted high cardiovascular and psychophysiological stress on the players. Reconsidering the given recovery time and the number of games allowed per day during national and international tournaments is highly recommended.
    Keywords Blood Lactate ; RPE ; Heart Rate ; Badminton ; Sports ; GV557-1198.995
    Subject code 796
    Language Arabic
    Publishing date 2021-10-01T00:00:00Z
    Publisher University of Basrah
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Lysosomes in retinal health and disease.

    Boya, Patricia / Kaarniranta, Kai / Handa, James T / Sinha, Debasish

    Trends in neurosciences

    2023  Volume 46, Issue 12, Page(s) 1067–1082

    Abstract: Lysosomes play crucial roles in various cellular processes - including endocytosis, phagocytosis, and autophagy - which are vital for maintaining retinal health. Moreover, these organelles serve as environmental sensors and act as central hubs for ... ...

    Abstract Lysosomes play crucial roles in various cellular processes - including endocytosis, phagocytosis, and autophagy - which are vital for maintaining retinal health. Moreover, these organelles serve as environmental sensors and act as central hubs for multiple signaling pathways. Through communication with other cellular components, such as mitochondria, lysosomes orchestrate the cytoprotective response essential for preserving cellular homeostasis. This coordination is particularly critical in the retina, given its high metabolic rate and susceptibility to photo-oxidative stress. Consequently, impaired lysosomal function and dysregulated communication between lysosomes and other organelles contribute significantly to the pathobiology of major retinal degenerative diseases. This review explores the pivotal role of lysosomes in retinal cells and their involvement in retinal degenerative diseases.
    MeSH term(s) Humans ; Retina ; Lysosomes/metabolism ; Autophagy/physiology ; Mitochondria/metabolism ; Endocytosis
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 282488-7
    ISSN 1878-108X ; 0378-5912 ; 0166-2236
    ISSN (online) 1878-108X
    ISSN 0378-5912 ; 0166-2236
    DOI 10.1016/j.tins.2023.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents.

    Maestro, Ines / Madruga, Enrique / Boya, Patricia / Martínez, Ana

    Journal of enzyme inhibition and medicinal chemistry

    2022  Volume 38, Issue 1, Page(s) 2153841

    Abstract: SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind ...

    Abstract SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases, there are no reported inhibitors able to cross the BBB so far, being a field yet to be explored. In this context, a structure-based virtual screening against this kinase was performed, pointing out the deazapurine moiety as an interesting and easy-to-derivatize scaffold. Moreover, these inhibitors are able to i) exert neuroprotection in an
    MeSH term(s) Apoptosis ; Neuroprotective Agents/pharmacology ; Protein Serine-Threonine Kinases/antagonists & inhibitors
    Chemical Substances Neuroprotective Agents ; Protein Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2022-12-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2082578-X
    ISSN 1475-6374 ; 1475-6366
    ISSN (online) 1475-6374
    ISSN 1475-6366
    DOI 10.1080/14756366.2022.2153841
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top