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  1. Article ; Online: Commentary.

    Yip, Hon Chi / Chiu, Philip Wai-Yan

    Endoscopy

    2022  Volume 54, Issue 8, Page(s) 830

    Language English
    Publishing date 2022-07-27
    Publishing country Germany
    Document type Journal Article ; Comment
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1803-0574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
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    Zs.MO 162: Show issues

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  2. Article ; Online: Endoscopic ultrasound-guided transduodenal ERCP for hepatico-jejunostomy stricture.

    Teh, Jun Liang / Chan, Shannon M / Yip, Hon Chi / Teoh, Anthony Yuen Bun

    Endoscopy

    2024  Volume 56, Issue S 01, Page(s) E25–E26

    MeSH term(s) Humans ; Cholangiopancreatography, Endoscopic Retrograde ; Constriction, Pathologic/etiology ; Constriction, Pathologic/surgery ; Jejunostomy ; Endosonography ; Ultrasonography, Interventional
    Language English
    Publishing date 2024-01-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2218-2260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article: Endoscopic ultrasound-guided transduodenal ERCP for hepatico-jejunostomy stricture

    Teh, Jun Liang / Chan, Shannon M / Yip, Hon Chi / Teoh, Anthony Yuen Bun

    Endoscopy

    2024  Volume 56, Issue S 01, Page(s) E25–E26

    Language English
    Publishing date 2024-01-09
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2218-2260
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

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  4. Article: Commentary

    Yip, Hon Chi / Chiu, Philip Wai-yan

    Endoscopy

    2022  Volume 54, Issue 08, Page(s) 830–830

    Language English
    Publishing date 2022-07-27
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1803-0574
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
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  5. Article ; Online: MFGE8 in exosomes derived from mesenchymal stem cells prevents esophageal stricture after endoscopic submucosal dissection in pigs.

    Lai, Huasheng / Yip, Hon-Chi / Gong, Yu / Chan, Kai-Fung / Leung, Kevin Kai-Chung / Chan, Melissa Shannon / Xia, Xianfeng / Chiu, Philip Wai-Yan

    Journal of nanobiotechnology

    2024  Volume 22, Issue 1, Page(s) 143

    Abstract: Background: Endoscopic submucosal dissection (ESD) is the current standard treatment for early-stage esophageal neoplasms. However, the postoperative esophageal stricture after extensive mucosal dissection remains a severe challenge with limited ... ...

    Abstract Background: Endoscopic submucosal dissection (ESD) is the current standard treatment for early-stage esophageal neoplasms. However, the postoperative esophageal stricture after extensive mucosal dissection remains a severe challenge with limited effective treatments available. In this study, we introduced a chitosan/gelatin (ChGel) sponge encapsulating the adipose mesenchymal stem cells (ADMSCs)-derived exosomes (ChGel
    Results: Pigs were randomly assigned into (1) ChGel
    Conclusions: Our study demonstrates that exosomal MFGE8 significantly promotes the polarization of the M2b-macrophage subset, consequently reducing collagen deposition. These findings suggest a promising potential for MSC-Exo therapy in preventing the development of esophageal stricture after near-circumferential ESD.
    MeSH term(s) Swine ; Animals ; Esophageal Stenosis/etiology ; Esophageal Stenosis/prevention & control ; Endoscopic Mucosal Resection/methods ; Chromatography, Liquid ; Exosomes ; Tandem Mass Spectrometry ; Mesenchymal Stem Cells ; Collagen
    Chemical Substances Collagen (9007-34-5)
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-024-02429-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Curative endoscopic full-thickness resection of a fundic gland-type gastric adenocarcinoma.

    Scheppach, Markus W / Ng, Stephen Ka Kei / Ni, Shelly / Chiu, Philip Wai Yan / Yip, Hon Chi

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2023  Volume 9, Issue 2, Page(s) 72–74

    Abstract: Video 1Summary of the presented case. Macroscopic images of the lesion in a white-light endoscopy and narrow-band imaging and in an underwater view followed by scenes from the resection with circular marking, submucosal injection, circumferential ... ...

    Abstract Video 1Summary of the presented case. Macroscopic images of the lesion in a white-light endoscopy and narrow-band imaging and in an underwater view followed by scenes from the resection with circular marking, submucosal injection, circumferential incision, and submucosal dissection using a multi-bend double-channel endoscope, as well as clip traction, controlled full-thickness dissection, and inspection of the defect plus closure of the defect with the clip-and-loop technique.
    Language English
    Publishing date 2023-10-21
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2023.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Endoscopic ultrasound-guided gallbladder drainage using a novel cautery-enhanced, endoscopist-deployed lumen-apposing metal stent.

    Ong, Lester Wei Lin / Chan, Shannon Melissa / Yip, Hon Chi / Teoh, Anthony Yuen Bun

    Endoscopy

    2022  Volume 54, Issue S 02, Page(s) E800–E801

    Language English
    Publishing date 2022-05-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1806-1646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 162: Show issues

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  8. Article: Endoscopic full-thickness resection (EFTR) compared to submucosal tunnel endoscopic resection (STER) for treatment of gastric gastrointestinal stromal tumors.

    Chiu, Philip Wai Yan / Yip, Hon Chi / Chan, Shannon Melissa / Ng, Stephen Ka Kei / Teoh, Anthony Yuen Bun / Ng, Enders Kwok Wai

    Endoscopy international open

    2023  Volume 11, Issue 2, Page(s) E179–E186

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2023-02-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1972-3409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ZNF746 plays cardinal roles on colorectal cancer (CRC) cell invasion and migration and regulates mitochondrial dynamics and morphological changes of CRC cells-Role of combined melatonin and 5-FU regimen.

    Huang, Chi-Ruei / Chu, Yu-Ting / Chang, Chia-Lo / Yip, Hon-Kan / Chen, Hong-Hwa

    Journal of cellular biochemistry

    2023  Volume 125, Issue 2, Page(s) e30507

    Abstract: The underlying mechanism of colorectal cells developing into cancer cells has been extensively investigated, yet is still not fully delineated, resulting in the treatment of advanced colorectal cancer (CRC) remains regrettably an unmet need. Zinc Finger ... ...

    Abstract The underlying mechanism of colorectal cells developing into cancer cells has been extensively investigated, yet is still not fully delineated, resulting in the treatment of advanced colorectal cancer (CRC) remains regrettably an unmet need. Zinc Finger Protein 746/Parkin-interacting substrate (ZNF746/PARIS) has previously been identified to play a fundamental role on bladder cancer cell proliferation and metastasis that were effectively inhibited by melatonin (Mel). In this study, we utilized ex vivo/in vivo studies to verify whether the ZNF746 signaling was also crucial in CRC growth/invasion/migration. Tissue-bank specimens showed that the protein expression of ZNF746 was significantly increased in CRC than that of healthy colorectal tissues (p < 0.001). Additionally, in vitro study demonstrated that excessive expression of ZNF746 significantly inhibited mitochondrial activity via (1) interfering with the dynamic balance of mitochondrial fusion/fission and (2) inhibiting the protein expression of MFN1/MFN2/PGC1a (all p < 0.001). Furthermore, we identified that inhibition of ZNF746 protein expression significantly reduced the resistance of CRC cell lines to the anticancer drug of 5-FU (p < 0.001), whereas overexpression of ZNF746 significantly augmented resistance of CRC cells to 5-FU (all p < 0.001). Finally, using the cell culture method, we found that combined Mel and 5-FU was superior to merely one on promoting the CRC cell apoptosis (p < 0.001). Our results confirmed that ZNF746 signaling played a cardinal role of CRC cell proliferation/survival and combined Mel and 5-FU treatment attenuated the resistance of CRC cells to the drug mainly through suppressing this signaling.
    MeSH term(s) Humans ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Cell Line, Tumor ; Melatonin/pharmacology ; Melatonin/therapeutic use ; Mitochondrial Dynamics ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Cell Proliferation ; Drug Resistance, Neoplasm ; Repressor Proteins/metabolism
    Chemical Substances Fluorouracil (U3P01618RT) ; Melatonin (JL5DK93RCL) ; ZNF746 protein, human ; Repressor Proteins
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392402-6
    ISSN 1097-4644 ; 0730-2312
    ISSN (online) 1097-4644
    ISSN 0730-2312
    DOI 10.1002/jcb.30507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1114: Show issues Location:
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  10. Article ; Online: Melatonin-Assisted Cisplatin Suppresses Urinary Bladder Cancer Cell Proliferation and Growth through Inhibiting PrP

    Yang, Chih-Chao / Chuang, Fei-Chi / Chang, Chia-Lo / Huang, Chi-Ruei / Chen, Hong-Hwa / Yip, Hon-Kan / Chen, Yen-Ta

    International journal of molecular sciences

    2023  Volume 24, Issue 4

    Abstract: This study investigated whether melatonin (Mel) would promote cisplatin to suppress the proliferation and growth of bladder cancer (BC) cells by inhibiting cellular prion protein ( ... ...

    Abstract This study investigated whether melatonin (Mel) would promote cisplatin to suppress the proliferation and growth of bladder cancer (BC) cells by inhibiting cellular prion protein (PrP
    MeSH term(s) Animals ; Humans ; Mice ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Cisplatin ; Cytochromes ; Matrix Metalloproteinase 9 ; Melatonin/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Urinary Bladder Neoplasms/metabolism ; PrPC Proteins
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Cytochromes ; Matrix Metalloproteinase 9 (EC 3.4.24.35) ; Melatonin (JL5DK93RCL) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; PrPC Proteins
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24043353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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