LIVIVO - Search results -

Search results

Result 1 - 10 of total 26

Search options

Article ; Online: Numerical assessment of hemodynamic perspectives of a left ventricular assist device and subsequent proposal for improvisation.

Ray, Pulak Kumar / Das, Arup Kumar / Das, Prasanta Kumar

2022 Volume 151, Issue Pt A, Page(s) 106309

Abstract: Due to the unavailability of donors, the use of left ventricular assist devices has emerged to be a reliable line of alternative treatment for heart failure. However, ventricular assist devices (VAD) have been associated with several postoperative ... ...

Abstract	Due to the unavailability of donors, the use of left ventricular assist devices has emerged to be a reliable line of alternative treatment for heart failure. However, ventricular assist devices (VAD) have been associated with several postoperative complications such as thrombosis, hemolysis, etc. Despite considerable improvements in technology, blood trauma due to high shear stress generation has been a major concern that is largely related to the geometrical feature of the VAD. This study aims to establish the design process of a centrifugal pump by considering several variations in the geometrical feature of a base design using the commercial solver ANSYS-CFX. To capture the uncertain behavior of blood as fluid, Newtonian, as well as non-Newtonian (Bird-Carreau model), models are used for flow field prediction. To assess the possibility of blood damage maximum wall shear stress and hemolysis index have been estimated for each operating point. The results of the simulations yield an optimized design of the pump based on parameters like pressure head generation, maximum shear stress, hydraulic efficiency, and hemolysis index. Further, the design methodology and the steps of development discussed in the paper can serve as a guideline for developing small centrifugal pumps handling blood.
MeSH term(s)	Humans ; Heart-Assist Devices ; Hemolysis ; Hemodynamics ; Heart Failure/surgery ; Stress, Mechanical
Language	English
Publishing date	2022-11-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	127557-4
ISSN	1879-0534 ; 0010-4825
ISSN (online)	1879-0534
ISSN	0010-4825
DOI	10.1016/j.compbiomed.2022.106309
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 653: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior.

Pastorino, Nicole G / Tomatsu, Saori / Lin, Amy / Doerr, Jackson / Waterman, Zachary / Sershen, Krisztina / Ray, Pulak / Rodriguez, Analiz / Galileo, Deni S

Journal of visualized experiments : JoVE

2023 , Issue 195

Abstract: The chick embryo has been an ideal model system for the study of vertebrate development, particularly for experimental manipulations. Use of the chick embryo has been extended for studying the formation of human glioblastoma (GBM) brain tumors in vivo ... ...

Abstract	The chick embryo has been an ideal model system for the study of vertebrate development, particularly for experimental manipulations. Use of the chick embryo has been extended for studying the formation of human glioblastoma (GBM) brain tumors in vivo and the invasiveness of tumor cells into surrounding brain tissue. GBM tumors can be formed by injection of a suspension of fluorescently labeled cells into the E5 midbrain (optic tectum) ventricle in ovo. Depending on the GBM cells, compact tumors randomly form in the ventricle and within the brain wall, and groups of cells invade the brain wall tissue. Thick tissue sections (350 µm) of fixed E15 tecta with tumors can be immunostained to reveal that invading cells often migrate along blood vessels when analyzed by 3D reconstruction of confocal z-stack images. Live E15 midbrain and forebrain slices (250-350 µm) can be cultured on membrane inserts, where fluorescently labeled GBM cells can be introduced into non-random locations to provide ex vivo co-cultures to analyze cell invasion, which also can occur along blood vessels, over a period of about 1 week. These ex vivo co-cultures can be monitored by widefield or confocal fluorescence time-lapse microscopy to observe live cell behavior. Co-cultured slices then can be fixed, immunostained, and analyzed by confocal microscopy to determine whether or not the invasion occurred along blood vessels or axons. Additionally, the co-culture system can be used for investigating potential cell-cell interactions by placing aggregates of different cell types and colors in different precise locations and observing cell movements. Drug treatments can be performed on ex vivo cultures, whereas these treatments are not compatible with the in ovo system. These two complementary approaches allow for detailed and precise analyses of human GBM cell behavior and tumor formation in a highly manipulatable vertebrate brain environment.
MeSH term(s)	Chick Embryo ; Animals ; Humans ; Glioblastoma ; Cerebral Ventricles ; Mesencephalon ; Prosencephalon ; Brain Neoplasms
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Journal Article ; Video-Audio Media ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/65199
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Interfacial synthesis of large-area ultrathin polyimine nanofilms as molecular separation membrane.

Tiwari, Karishma / Modak, Solagna / Sarkar, Pulak / Ray, Santanu / Adupa, Vasista / Reddy, K Anki / Pramanik, Sumit Kumar / Das, Amitava / Karan, Santanu

iScience

2022 Volume 25, Issue 4, Page(s) 104027

Abstract: Thin film membranes of covalent organic frameworks are promising for high-permeance molecular separation. However, their synthesis needs a high temperature or longer reaction time, unsuitable for large-scale fabrication of thin film composite membranes. ... ...

Abstract	Thin film membranes of covalent organic frameworks are promising for high-permeance molecular separation. However, their synthesis needs a high temperature or longer reaction time, unsuitable for large-scale fabrication of thin film composite membranes. The ultrathin film of porous organic polymers as a separation layer of the composite membrane could be a close alternative to COF membranes. Here we report transition metal ion-catalyzed room temperature fabrication of the ultrathin (≈12 nm) polyimine nanofilms via interfacial polymerization of melamine and triformylphloroglucinol onto hydrolyzed polyacrylonitrile support within a short reaction time. Composite membranes exhibit high water permeance (≈78 L m
Language	English
Publishing date	2022-03-04
Publishing country	United States
Document type	Journal Article
ISSN	2589-0042
ISSN (online)	2589-0042
DOI	10.1016/j.isci.2022.104027
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Interfacial synthesis of large-area ultrathin polyimine nanofilms as molecular separation membrane

Karishma Tiwari / Solagna Modak / Pulak Sarkar / Santanu Ray / Vasista Adupa / K. Anki Reddy / Sumit Kumar Pramanik / Amitava Das / Santanu Karan

iScience, Vol 25, Iss 4, Pp 104027- (2022)

2022

Abstract: Summary: Thin film membranes of covalent organic frameworks are promising for high-permeance molecular separation. However, their synthesis needs a high temperature or longer reaction time, unsuitable for large-scale fabrication of thin film composite ... ...

Abstract	Summary: Thin film membranes of covalent organic frameworks are promising for high-permeance molecular separation. However, their synthesis needs a high temperature or longer reaction time, unsuitable for large-scale fabrication of thin film composite membranes. The ultrathin film of porous organic polymers as a separation layer of the composite membrane could be a close alternative to COF membranes. Here we report transition metal ion-catalyzed room temperature fabrication of the ultrathin (≈12 nm) polyimine nanofilms via interfacial polymerization of melamine and triformylphloroglucinol onto hydrolyzed polyacrylonitrile support within a short reaction time. Composite membranes exhibit high water permeance (≈78 L m−2 h−1 bar−1), high rejection (99.6%) of brilliant blue R (825.9 g mol−1), low rejection of NaCl (≈1.8%) and Na2SO4 (≈17%), and enable efficient molecular separation. The role of metal ion catalysts for large-area fabrication of the ultrathin polyimine nanofilm membranes used for molecular separation is demonstrated.
Keywords	Nanotechnology ; Membranes ; Materials sciences ; Science ; Q
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Fast water transport through sub-5 nm polyamide nanofilms: the new upper-bound of the permeance–selectivity trade-off in nanofiltration

Sarkar, Pulak / Modak, Solagna / Ray, Santanu / Adupa, Vasista / Reddy, K. Anki / Karan, Santanu

Journal of materials chemistry A. 2021 Sept. 21, v. 9, no. 36

2021

Abstract: Liquid transport through a composite membrane is inversely proportional to the thickness of its separation layer. While the scalable fabrication of ultrathin polymer membranes is sought for their commercial exploitation, there is an indispensable need to ...

Abstract	Liquid transport through a composite membrane is inversely proportional to the thickness of its separation layer. While the scalable fabrication of ultrathin polymer membranes is sought for their commercial exploitation, there is an indispensable need to understand the ion sieving property of ultrathin polymer films. Here, the fabrication of composite membranes with a sub-5 nm thick polyamide nanofilm selective layer fabricated by controlled post-solvent-washing and post-heating of the nascent nanofilm formed via interfacial polymerization of piperazine (PIP) and trimesoyl chloride (TMC) is reported. The post-solvent-washing step removes the unreacted TMC from the surface of the nascent nanofilm and prohibits further growth of the nanofilm during the post-heating process necessary to achieve a desired crosslinked structure. Post-solvent-washing helps design nanofilms with a controlled surface charge and produces the ultrathin separation layer (∼4.5 nm) of the composite membrane. Nanofilm composite membranes show ultrahigh water permeance of 30.1–68.0 L m⁻² h⁻¹ bar⁻¹, under a working pressure of 5 bar and showed 96.0–99.82% rejection of a divalent salt (Na₂SO₄). The monovalent (Cl⁻) to divalent (SO₄²⁻) ion selectivity establishes a global upper-bound of the permeance–selectivity trade-off for the nanofiltration membranes and also delivers an extremely high ion selectivity (1256) in mixed salts.
Keywords	asymmetric membranes ; crosslinking ; liquids ; nanofiltration ; nanosheets ; piperazine ; polyamides ; polymerization ; trimesoyl chloride
Language	English
Dates of publication	2021-0921
Size	p. 20714-20724.
Publishing place	The Royal Society of Chemistry
Document type	Article
ZDB-ID	2702232-8
ISSN	2050-7496 ; 2050-7488
ISSN (online)	2050-7496
ISSN	2050-7488
DOI	10.1039/d1ta04763a
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Development of an orthosis for simultaneous three-dimensional correction of clubfoot deformity.

Khas, Kanwaljit S / Pandey, Pulak M / Ray, Alok R

Clinical biomechanics (Bristol, Avon)

2017 Volume 51, Page(s) 67–75

Abstract: Background: Clubfoot is a three-dimensional deformity of the foot in which the foot is twisted in three mutually perpendicular planes from the normal shape of the foot. Of the various treatment methods that are available to manage clubfoot, non- ... ...

Abstract	Background: Clubfoot is a three-dimensional deformity of the foot in which the foot is twisted in three mutually perpendicular planes from the normal shape of the foot. Of the various treatment methods that are available to manage clubfoot, non-operative approaches are preferred. The conventional non-operative method of treatment is to apply a series of casts to the infant's clubfoot to gradually manipulate its position. However, prolonged use of casts can result in skin rash, skin dehydration and ulcers on the soft skin of an infant. Treatment using orthosis represents an alternative non-operative and convenient technique because an orthosis can be put on and taken off at any time. Methods: In the present study, an orthosis was developed according to the rotation of three mutually perpendicular planes and was subsequently tested on five patients over the duration of one week. Findings: In all five cases, the desired incremental correction to the clubfoot was achieved through the one week intervention with the orthosis. No form of rash, dehydration, ulcers, and so on were observed on the skin of any baby involved in the study during or following application of the orthosis. Interpretation: By using the developed orthosis, partial correction of the clubfoot deformity was achieved over a short period of time. However the widespread use of this device for extended durations and with a larger number of patients will generate further evidence of the extent to which this orthosis can reliably treat clubfoot.
MeSH term(s)	Braces ; Casts, Surgical ; Clubfoot/physiopathology ; Clubfoot/therapy ; Female ; Humans ; Imaging, Three-Dimensional ; Infant, Newborn ; Male ; Orthotic Devices ; Range of Motion, Articular/physiology ; Secondary Prevention ; Splints ; Treatment Outcome
Language	English
Publishing date	2017-12-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632747-3
ISSN	1879-1271 ; 0268-0033
ISSN (online)	1879-1271
ISSN	0268-0033
DOI	10.1016/j.clinbiomech.2017.12.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2876: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Design and development of a device to measure the deformities of clubfoot.

Khas, Kanwaljit S / Pandey, Pulak M / Ray, Alok R

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

2015 Volume 229, Issue 3, Page(s) 194–204

Abstract: Clubfoot describes a range of foot abnormalities usually present at birth, in which the foot of a baby is twisted out of shape or position. In order to develop an effective treatment plan for clubfoot and/or assess the extent to which existing ... ...

Abstract	Clubfoot describes a range of foot abnormalities usually present at birth, in which the foot of a baby is twisted out of shape or position. In order to develop an effective treatment plan for clubfoot and/or assess the extent to which existing interventions are successful, medical practitioners need to be able to accurately measure the nature and extent of the deformity. This is typically performed using a goniometer. However, this device is only able to measure one dimension at a time. As such, a complete assessment of the condition of a foot can be extremely burdensome and time-consuming. This article describes a new device that can quickly and efficiently take several measurements on feet of various sizes and shapes. The use of this device was verified by measuring the deformities of real clubfeet. A silicone rubber clubfoot model was also used in this study to clearly illustrate the effectiveness with which the proposed device can measure the various deformities of clubfoot. It is envisaged that the use of this device will significantly reduce the time and effort orthopedists require to measure clubfoot deformities and develop and assess treatment plans.
MeSH term(s)	Clubfoot/diagnosis ; Clubfoot/pathology ; Clubfoot/physiopathology ; Equipment Design ; Humans ; Imaging, Three-Dimensional/instrumentation ; Imaging, Three-Dimensional/methods ; Models, Biological ; Range of Motion, Articular/physiology
Language	English
Publishing date	2015-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1065942-0
ISSN	2041-3033 ; 0046-2039 ; 0954-4119
ISSN (online)	2041-3033
ISSN	0046-2039 ; 0954-4119
DOI	10.1177/0954411915574758
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2652: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Overcoming barriers to social inclusion in agricultural intensification

Roth, Christian H. / Cosijn, Michaela / Carter, Lucy / Chakraborty, Arnab / Das, Mahanambrota / Hamilton, Serena H. / Jana, Alak Kumar / Lim-Camacho, Lilly / Majumdar, Subrata / Merritt, Wendy S. / Mishra, Pulak / Mishra, Rajeshwar / Nidumolu, Uday / Rahman, Md Wakilur / Ray, Dhananjay / Williams, Liana J.

Community Development Journal

reflections on a transdisciplinary community development project from India and Bangladesh

2023

Abstract: We describe a research-for-development (R4D) strategy developed to address how investments and interventions in agricultural intensification as a means to achieve community development can be designed to be more socially inclusive and equitable. We draw ... ...

Abstract	We describe a research-for-development (R4D) strategy developed to address how investments and interventions in agricultural intensification as a means to achieve community development can be designed to be more socially inclusive and equitable. We draw on results from a 5-year project – Promoting socially inclusive and sustainable agricultural intensification in West Bengal (India) and southern Bangladesh (SIAGI). We reflect on a major pivot in the project’s strategy, from being primarily research-driven to placing community concerns and priorities at the centre with a shift towards Ethical Community Engagement (ECE). This became the foundational framework which guided the definition and undertaking of all subsequent activities – including a rethink of methods and concepts to develop tools and frameworks fit for purpose and local context, and inculcating a culture of reflexivity and mutual learning in the project. We show that creating the conditions for true participation, where project beneficiaries and non-government organizations are equal partners alongside researchers and government actors, and for co-learning using the ECE framework, sets the foundations for increased and potentially enduring social inclusion in agricultural intensification.
Keywords	climate change ; food systems ; deltas ; food security ; agriculture
Language	English
Publishing date	2023-09-08T11:40:33Z
Publisher	Oxford University Press
Publishing country	fr
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: A parametric variant of resonant activation: two-state model approach.

Ghosh, Pulak Kumar / Ray, Deb Shankar

The Journal of chemical physics

2006 Volume 125, Issue 12, Page(s) 124102

Abstract: Mean first passage time of a periodically driven particle for its escape over a fluctuating barrier with wells remaining unbiased exhibits a resonance when the frequency of the driving field is varied. This parametric variant of resonant activation and ... ...

Abstract	Mean first passage time of a periodically driven particle for its escape over a fluctuating barrier with wells remaining unbiased exhibits a resonance when the frequency of the driving field is varied. This parametric variant of resonant activation and associated features of noise induced transition are realized in terms of a two-state model to estimate analytically several quantifiers of the escape event. Numerical simulation on a continuous double-well model collaborates our theoretical analysis.
Language	English
Publishing date	2006-09-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	3113-6
ISSN	1089-7690 ; 0021-9606
ISSN (online)	1089-7690
ISSN	0021-9606
DOI	10.1063/1.2348867
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 49/16: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Stochastic energetics of quantum transport.

Ghosh, Pulak Kumar / Ray, Deb Shankar

Physical review. E, Statistical, nonlinear, and soft matter physics

2006 Volume 73, Issue 3 Pt 2, Page(s) 36103

Abstract: We examine the stochastic energetics of directed quantum transport due to rectification of nonequilibrium thermal fluctuations. We calculate the quantum efficiency of a ratchet device both in presence and absence of an external load to characterize two ... ...

Abstract	We examine the stochastic energetics of directed quantum transport due to rectification of nonequilibrium thermal fluctuations. We calculate the quantum efficiency of a ratchet device both in presence and absence of an external load to characterize two quantifiers of efficiency. It has been shown that the quantum current as well as efficiency in absence of load (Stokes efficiency) is higher as compared to classical current and efficiency, respectively, at low temperature. The conventional efficiency of the device in presence of load on the other hand is higher for a classical system in contrast to its classical counterpart. The maximum conventional efficiency being independent of the nature of the bath and the potential remains the same for classical and quantum systems.
Language	English
Publishing date	2006-03
Publishing country	United States
Document type	Journal Article
ISSN	1539-3755
ISSN	1539-3755
DOI	10.1103/PhysRevE.73.036103
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED