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Article ; Online: Sicilians' knowledge, perceptions, prevention and practices during the pandemic in relation to vaccination: A questionnaire-based survey.

Basha, Sami / Salameh, Basma

2023 Volume 30, Issue 4, Page(s) 16–24

Abstract: Background: COVID-19 has influenced Sicily, Italy as any other part of the world, and people had various types of reactions to this global epidemic. This study aimed to assess the behavior, perception, and willingness of the Sicilian population to ... ...

Abstract	Background: COVID-19 has influenced Sicily, Italy as any other part of the world, and people had various types of reactions to this global epidemic. This study aimed to assess the behavior, perception, and willingness of the Sicilian population to accept vaccination, as well as their attitudes toward conspiracy theories, which have been a concern for governments around the globe. Methods: Study design: cross sectional-descriptive study. The data were collected through a survey developed based on a protocol from the World Health Organization's regional office in Europe, which was distributed in two waves. The first wave took place in April and May 2020, and a modified survey was distributed during June and July. Results: Sicilians showed a very good knowledge of the virus, while their positive attitude has changed toward vaccination in the second wave. Furthermore, Sicilians showed an average trust in the governmental institutions, which allow the doubts of conspiracy to exist in the population. Conclusions: Although the results indicate a good level of knowledge and positive attitude toward vaccination, we believe that further studies should be conducted in the Mediterranean to better understand how to face future epidemics with limited resources in the healthcare system, as compared with other countries.
MeSH term(s)	Humans ; Pandemics/prevention & control ; Cross-Sectional Studies ; Vaccination ; COVID-19/epidemiology ; COVID-19/prevention & control ; Surveys and Questionnaires
Language	English
Publishing date	2023-06-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2502036-5
ISSN	1757-9767 ; 1757-9759
ISSN (online)	1757-9767
ISSN	1757-9759
DOI	10.1177/17579759231168652
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Article ; Online: Knowledge, Perceptions, and Prevention Practices among Palestinian University Students during the COVID-19 Pandemic: A Questionnaire-Based Survey.

Salameh, Basma / Basha, Sami / Basha, Walid / Abdallah, Jihad

Inquiry : a journal of medical care organization, provision and financing

2021 Volume 58, Page(s) 46958021993944

Abstract: The purpose of this study is to offer a timely understanding of university students' knowledge, perception, and preventative practices related to COVID-19 in Palestine and to determine affecting factors (gender, region, and type of locality). A cross- ... ...

Abstract	The purpose of this study is to offer a timely understanding of university students' knowledge, perception, and preventative practices related to COVID-19 in Palestine and to determine affecting factors (gender, region, and type of locality). A cross-sectional design was used and data was collected over 2 weeks in April 2020 through an online survey. A total of 484 surveys were collected from students from different Palestinian universities. Participants showed high levels of knowledge across multiple topics (symptoms and characteristics of COVID-19, prevention practices, and at-risk groups), although respondents were less likely to indicate mask wearing as an effective prevention practice compared to other practices, and almost one-third reported incorrectly that taking antibiotics is effective in preventing COVID-19 infection. Respondents reported the most trust in the Ministry of Health as a source of information, and the least trust in social media. A generally high level of acceptance of government regulations related to the COVID-19 pandemic was found. Given the current global situation and the second wave of infections in Palestine, plans should be in place to disseminate correct information and combat newly-emerging rumors and misinformation through channels that are trusted by the university student population.
MeSH term(s)	Adult ; Arabs/psychology ; Arabs/statistics & numerical data ; COVID-19/epidemiology ; COVID-19/psychology ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Public Opinion ; Students/psychology ; Students/statistics & numerical data ; Surveys and Questionnaires ; Universities ; Young Adult
Language	English
Publishing date	2021-02-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	42153-4
ISSN	1945-7243 ; 0046-9580
ISSN (online)	1945-7243
ISSN	0046-9580
DOI	10.1177/0046958021993944
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Article ; Online: Early perception, behavior, knowledge, and preventive practices related to COVID-19 among Palestinians.

Salameh, Basma Salim / Basha, Sami / Abdallah, Jihad / Basha, Walid

Global health promotion

2021 Volume 29, Issue 1, Page(s) 33–43

Abstract: It is necessary to understand early perception, behavior, and knowledge of coronavirus disease 2019 (COVID-19) and preventive practices in relation to suggested policies and information accessible to the Palestinian population during the early stages of ... ...

Abstract	It is necessary to understand early perception, behavior, and knowledge of coronavirus disease 2019 (COVID-19) and preventive practices in relation to suggested policies and information accessible to the Palestinian population during the early stages of the pandemic. The aim of this research is to contribute to this understanding for the purpose of affecting future practical preventive policies that can be implemented and adapted in Palestine in order to shape a new reflective practices model to face any future epidemic crisis of any type. A cross-sectional design was used to conduct the study over 3 weeks in April 2020 and an online survey was disseminated in all areas of Palestine. A total of 1040 responses were collected from persons who were over 18 years of age. A high level of knowledge related to COVID-19 was found, including symptoms and characteristics of the virus, prevention practices, and at-risk groups. Respondents believe that they are more susceptible to influenza than COVID-19 and more likely to be infected by the influenza virus than the COVID-19 virus but expect that infection of influenza would be less severe than infection of COVID-19. Respondents were more inclined to find COVID-19 worrying and stressful than they were to find it fear-inducing. Around two-thirds of respondents believe that different types of COVID-19-related conspiracy theories are true to some degree. Going forward, it is crucial and essential to provide basic awareness among large populations around diseases, which can contribute to positively influencing people's knowledge and attitudes and their perception toward such diseases and combat conspiracy theories.
MeSH term(s)	Adolescent ; Adult ; Arabs ; COVID-19/epidemiology ; COVID-19/prevention & control ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Humans ; Influenza, Human ; Perception ; Surveys and Questionnaires
Language	English
Publishing date	2021-09-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2502036-5
ISSN	1757-9767 ; 1757-9759
ISSN (online)	1757-9767
ISSN	1757-9759
DOI	10.1177/17579759211035092
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Article ; Online: Immunohistochemical Analysis of Endothelial Cells in Vascular Transformation of Lymph Node Sinuses: Vascular or Lymphatic Differentiation?

Basha, Basma M / Hsi, Eric D

Applied immunohistochemistry & molecular morphology : AIMM

2018 Volume 27, Issue 6, Page(s) 482–489

Abstract: Introduction: Vascular transformation of sinuses (VTS) is an uncommon and benign lesion, defined by conversion of lymph node sinuses into complex, anatomizing and endothelial-lined channels. Despite the name of VTS, which implies a change in ... ...

Abstract	Introduction: Vascular transformation of sinuses (VTS) is an uncommon and benign lesion, defined by conversion of lymph node sinuses into complex, anatomizing and endothelial-lined channels. Despite the name of VTS, which implies a change in differentiation from lymphatic to vascular endothelium, very few studies have systematically examined VTS with modern immunohistochemical markers commonly used in clinical laboratories. It is unclear whether endothelial cells in VTS display pure vascular or lymphatic differentiation, or both. Design: A total of 11 cases with a diagnosis of VTS (identified in the tissue archives of the Cleveland Clinic between 1992 and 2015) were reviewed and confirmed. Twenty cases of benign lymph nodes without specific diagnoses were used as control tissues. Immunohistochemical stains were performed on formalin-fixed, paraffin-embedded lymph node tissue using an automated immunohistochemistry platform with antibodies against CD31, CD34, D2-40, and ERG. Positivity in the VTS lesions was defined as distinct expression in the appropriate cell compartment in ≥20% of cells. In control cases, staining was evaluated in both vascular and lymphatic channels-vascular structures were identified by presence of red cells or well-formed vascular walls and lymphatics by anatomic location and absence of vascular features. Results: In the VTS lesions, D2-40 expression was absent in the lesional endothelial cells of 5/11 (45%) cases. In the cases lacking D240 expression, uninvolved lymphatic endothelium maintained expression. CD34 expression was also seen in 6/11 (54%), CD31 was seen in 10/11 (90%), and ERG expression was seen in all cases. In all the control cases, D240 expression was exclusively seen in lymphatic endothelial cells and not seen in vascular endothelial cells (eg, vascular channels in the hilum). CD34 was weakly positive in the lymphatic endothelium of only 7/20 (35%) control cases, but expressed in 20/20 (100%) control cases in the vascular endothelium. 20/20 (100%) of control cases showed expression of CD31 and ERG in both vascular and lymphatic endothelium. Conclusion: VTS lesional endothelial cells demonstrate patterns of vascular markers that show mixed blood vascular and lymphatic features. There appears to be a degree of alignment toward endothelial differentiation with decreased expression of D2-40 in some cases.
MeSH term(s)	Adult ; Aged ; Antibodies, Monoclonal, Murine-Derived ; Antigens, CD34/metabolism ; Biomarkers, Tumor/metabolism ; Case-Control Studies ; Cell Differentiation ; Cell Transformation, Neoplastic ; Endothelium, Lymphatic/physiology ; Endothelium, Vascular/physiology ; Female ; Humans ; Immunohistochemistry ; Lymph Nodes/pathology ; Male ; Middle Aged ; Vascular Neoplasms/diagnosis ; Vascular Neoplasms/metabolism ; Vascular Neoplasms/pathology
Chemical Substances	Antibodies, Monoclonal, Murine-Derived ; Antigens, CD34 ; Biomarkers, Tumor ; monoclonal antibody D2-40
Language	English
Publishing date	2018-04-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1473273-7
ISSN	1533-4058 ; 1062-3345 ; 1541-2016
ISSN (online)	1533-4058
ISSN	1062-3345 ; 1541-2016
DOI	10.1097/PAI.0000000000000661
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Zs.A 3783: Show issues

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Article ; Online: Design, Validation, and Clinical Implementation of a Gap-Polymerase Chain Reaction Method for α-Thalassemia Genotyping Using Capillary Electrophoresis.

Basha, Basma / Mularo, Frank / Cook, James R

Hemoglobin

2017 Volume 41, Issue 2, Page(s) 124–130

Abstract: α-Thalassemia (α-thal) is genetically heterogeneous with most cases caused by variably sized deletions of the HBA1 and/or HBA2 loci. In this report, we describe the development, validation, and implementation of a novel gap-polymerase chain reaction (gap- ...

Abstract	α-Thalassemia (α-thal) is genetically heterogeneous with most cases caused by variably sized deletions of the HBA1 and/or HBA2 loci. In this report, we describe the development, validation, and implementation of a novel gap-polymerase chain reaction (gap-PCR)/capillary electrophoresis (CE). Method: This assay utilizes two multiplex reactions and CE to detect the following deletions: -α
Language	English
Publishing date	2017-03
Publishing country	England
Document type	Journal Article
ZDB-ID	750615-6
ISSN	1532-432X ; 0363-0269
ISSN (online)	1532-432X
ISSN	0363-0269
DOI	10.1080/03630269.2017.1327868
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Article: Essential Care Needs for Patients' Family Members at the Intensive Care Units in Palestine.

Salameh, Basma Salim Saleh / Basha, Sami Salim Saleh / Eddy, Linda Lee / Judeh, Hiba Salem / Toqan, Dalia Rahmi

Iranian journal of nursing and midwifery research

2020 Volume 25, Issue 2, Page(s) 154–159

Abstract: Background: Understanding the needs of families of hospital patients, especially those in intensive care units is key to providing comprehensive, effective support. The aim of this study is to determine the needs of families of Intensive Care Unit (ICU) ...

Abstract	Background: Understanding the needs of families of hospital patients, especially those in intensive care units is key to providing comprehensive, effective support. The aim of this study is to determine the needs of families of Intensive Care Unit (ICU) patients in four Palestinian hospitals. Materials and methods: This was a cross-sectional, analytic study including 240 participants selected using convenience sampling. Data was obtained from participants from September 2016 to April 2018. The Critical Care Family Needs Inventory (CCFNI) was distributed to examine their needs. Descriptive analysis, Results: The results revealed that the assurance domain was the most important, but participants had some unmet needs from the support domain. Parents reported higher levels of importance of all needs than other types of relatives of patients. In addition, participants with a higher level of education reported a significantly higher level of importance in the dimensions of assurance (F Conclusions: Family members of ICU patients have certain unmet needs, which require attention from healthcare professionals and administration in Palestinian hospitals. In addition, sociodemographic variables influence family member needs.
Language	English
Publishing date	2020-02-24
Publishing country	India
Document type	Journal Article
ZDB-ID	2609892-1
ISSN	2228-5504 ; 1735-9066
ISSN (online)	2228-5504
ISSN	1735-9066
DOI	10.4103/ijnmr.IJNMR_9_19
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Article ; Online: Knowledge, Perceptions, and Prevention Practices among Palestinian University Students during the COVID-19 Pandemic

Basma Salameh PhD, RN / Sami Basha PhD / Walid Basha PhD / Jihad Abdallah PhD

Inquiry: The Journal of Health Care Organization, Provision, and Financing, Vol

A Questionnaire-Based Survey

2021 Volume 58

Abstract: The purpose of this study is to offer a timely understanding of university students’ knowledge, perception, and preventative practices related to COVID-19 in Palestine and to determine affecting factors (gender, region, and type of locality). A cross- ... ...

Abstract	The purpose of this study is to offer a timely understanding of university students’ knowledge, perception, and preventative practices related to COVID-19 in Palestine and to determine affecting factors (gender, region, and type of locality). A cross-sectional design was used and data was collected over 2 weeks in April 2020 through an online survey. A total of 484 surveys were collected from students from different Palestinian universities. Participants showed high levels of knowledge across multiple topics (symptoms and characteristics of COVID-19, prevention practices, and at-risk groups), although respondents were less likely to indicate mask wearing as an effective prevention practice compared to other practices, and almost one-third reported incorrectly that taking antibiotics is effective in preventing COVID-19 infection. Respondents reported the most trust in the Ministry of Health as a source of information, and the least trust in social media. A generally high level of acceptance of government regulations related to the COVID-19 pandemic was found. Given the current global situation and the second wave of infections in Palestine, plans should be in place to disseminate correct information and combat newly-emerging rumors and misinformation through channels that are trusted by the university student population.
Keywords	Public aspects of medicine ; RA1-1270
Subject code	302
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: What Is the Clinical Utility of Repeat SNP Array Testing in the Follow-up of Myeloid Neoplasms?: A Retrospective Analysis of 44 Patients With Serial SNP Arrays.

Basha, Basma / Smith, Janice / Rogers, Heesun J / Cook, James R

American journal of clinical pathology

2017 Volume 147, Issue 3, Page(s) 278–284

Abstract: Objectives: Single-nucleotide polymorphism (SNP) arrays have been shown to identify cytogenetic abnormalities in myeloid neoplasms that may be missed by metaphase cytogenetics alone at initial diagnosis. This study examines the utility of serial SNP ... ...

Abstract	Objectives: Single-nucleotide polymorphism (SNP) arrays have been shown to identify cytogenetic abnormalities in myeloid neoplasms that may be missed by metaphase cytogenetics alone at initial diagnosis. This study examines the utility of serial SNP arrays in follow-up testing of myeloid neoplasms. Methods: We retrospectively reviewed results of SNP array testing in 44 patients with myeloid neoplasms and more than one SNP array study (n = 133 SNP arrays total; median, three per patient; range, two to eight per patient). Results: Baseline abnormalities were identified by SNP array in 35 (79%) of 44 (79%) compared with 18 (50%) of 36 by metaphase karyotype. In follow-up studies, clonal evolution was found by both SNP array and karyotyping in seven (15.9%), by metaphase karyotyping alone in six (13.6%), and SNP arrays alone in two (4.5%). Overall survival was not significantly different between patients with or without clonal evolution detected by SNP array. Conclusions: This study, the first systematic examination of serial SNP arrays in myeloid neoplasms, confirms the clinical utility of SNP arrays at initial diagnosis but shows that clonal evolution of the karyotype can be detected by metaphase cytogenetics alone in most patients. Follow-up SNP array testing is not required in routine clinical use in most cases.
MeSH term(s)	Aged ; Aged, 80 and over ; Chromosome Aberrations ; Female ; Follow-Up Studies ; Humans ; Karyotyping ; Male ; Middle Aged ; Myelodysplastic Syndromes/genetics ; Myelodysplastic Syndromes/mortality ; Myeloproliferative Disorders/genetics ; Myeloproliferative Disorders/mortality ; Oligonucleotide Array Sequence Analysis ; Polymorphism, Single Nucleotide/genetics ; Retrospective Studies
Language	English
Publishing date	2017-03-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2944-0
ISSN	1943-7722 ; 0002-9173
ISSN (online)	1943-7722
ISSN	0002-9173
DOI	10.1093/ajcp/aqx003
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Article ; Online: Application of a 5 Marker Panel to the Routine Diagnosis of Peripheral T-Cell Lymphoma With T-Follicular Helper Phenotype.

Basha, Basma M / Bryant, Sandra C / Rech, Karen L / Feldman, Andrew L / Vrana, Julie A / Shi, Min / Reed, Katelyn A / King, Rebecca L

The American journal of surgical pathology

2019 Volume 43, Issue 9, Page(s) 1282–1290

Abstract: The 2017 World Health Organization update introduced a new category of nodal peripheral T-cell lymphoma with T-follicular helper phenotype (PTCL-TFH) defined by expression of at least 2 or 3 TFH markers. Our study assesses the utility of an ... ...

Abstract	The 2017 World Health Organization update introduced a new category of nodal peripheral T-cell lymphoma with T-follicular helper phenotype (PTCL-TFH) defined by expression of at least 2 or 3 TFH markers. Our study assesses the utility of an immunohistochemical panel of 5 TFH markers (CD10, BCL6, PD-1, CXCL13, and ICOS) for identification of TFH phenotype in angioimmunoblastic T-cell lymphoma (AITL) and PTCL not otherwise specified (NOS). Immunohistochemical for the 5 markers was performed on 22 cases of AITL and 29 cases of PTCL-NOS. Cases were reviewed for morphologic features characteristic of AITL. All AITL cases showed expression of ≥2 TFH markers. This panel resulted in reclassification of 41% PTCL-NOS cases to PTCL-TFH. Positive percent agreement for the TFH phenotype is 97% for PD1, 94% for ICOS, 44% for CD10 and CXCL13, and 29% for BCL6. Negative percent agreement for TFH phenotype is 100% for CD10, BCL6, and CXCL13, 82% for ICOS and 71% for PD1. AITL cases were more likely than PTCL-TFH cases to contain expanded CD21-positive follicular dendritic cell meshworks, clear cell cytology and polymorphous inflammatory background; however, there was a significant (P<0.005) Kruskal-Wallis trend in all morphologic variables between the 3 groups suggesting a continuum from PTCL-NOS to PTCL-TFH to AITL. The median number of morphologic features of AITL also correlated significantly with number of TFH markers positive (Spearman coefficient ρ=0.759). In summary, the stain panel chosen will have an impact on cases classified as PTCL-TFH. This entity may exist along a spectrum between PTCL-NOS and AITL.
MeSH term(s)	Biomarkers, Tumor/analysis ; Germinal Center/immunology ; Humans ; Lymphoma, T-Cell, Peripheral/classification ; Lymphoma, T-Cell, Peripheral/diagnosis ; Lymphoma, T-Cell, Peripheral/immunology ; Phenotype ; T-Lymphocytes, Helper-Inducer/pathology
Chemical Substances	Biomarkers, Tumor
Language	English
Publishing date	2019-07-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	752964-8
ISSN	1532-0979 ; 0147-5185
ISSN (online)	1532-0979
ISSN	0147-5185
DOI	10.1097/PAS.0000000000001315
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Article ; Online: Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?

Basha, Basma / Samuel, Samson Mathews / Triggle, Chris R / Ding, Hong

Experimental diabetes research

2012 Volume 2012, Page(s) 481840

Abstract: The vascular complications of diabetes mellitus impose a huge burden on the management of this disease. The higher incidence of cardiovascular complications and the unfavorable prognosis among diabetic individuals who develop such complications have been ...

Abstract	The vascular complications of diabetes mellitus impose a huge burden on the management of this disease. The higher incidence of cardiovascular complications and the unfavorable prognosis among diabetic individuals who develop such complications have been correlated to the hyperglycemia-induced oxidative stress and associated endothelial dysfunction. Although antioxidants may be considered as effective therapeutic agents to relieve oxidative stress and protect the endothelium, recent clinical trials involving these agents have shown limited therapeutic efficacy in this regard. In the recent past experimental evidence suggest that endoplasmic reticulum (ER) stress in the endothelial cells might be an important contributor to diabetes-related vascular complications. The current paper contemplates the possibility of the involvement of ER stress in endothelial dysfunction and diabetes-associated vascular complications.
MeSH term(s)	Diabetes Mellitus/physiopathology ; Diabetic Angiopathies/physiopathology ; Endoplasmic Reticulum Stress/physiology ; Endothelium, Vascular/physiopathology ; Humans ; Hyperglycemia/physiopathology ; Oxidative Stress/physiology
Language	English
Publishing date	2012-02-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2465179-5
ISSN	1687-5303 ; 1687-5214
ISSN (online)	1687-5303
ISSN	1687-5214
DOI	10.1155/2012/481840
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