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Article ; Online: Exploring Eating Habits, Healthy Food Awareness, and Inclination toward Functional Foods of Italian Elderly People through Computer-Assisted Telephone Interviews (CATIs).

Daniele, Giulia Maria / Medoro, Chiara / Lippi, Nico / Cianciabella, Marta / Magli, Massimiliano / Predieri, Stefano / Versari, Giuseppe / Volpe, Roberto / Gatti, Edoardo

Nutrients

2024 Volume 16, Issue 6

Abstract: The continuous increase in life expectancy leads to progressive population ageing, especially in most developed countries. A healthy diet and better consumption of tailored functional foods may represent one of the strategies to postpone or slow down age- ...

Abstract	The continuous increase in life expectancy leads to progressive population ageing, especially in most developed countries. A healthy diet and better consumption of tailored functional foods may represent one of the strategies to postpone or slow down age-related decrements, thus increasing healthy ageing and reducing healthcare costs. This research aimed to explore elderly people's (>65 years old) eating habits and assess their awareness of food-health correlation. In total, 511 Italian seniors answered a CATI (computer-assisted telephone interviewing) questionnaire through a deep, telephone interview to collect information about dietary habits, healthy food awareness, and inclination for functional foods. The elderly were divided into four groups according to gender and age: Early Elderly Female (
MeSH term(s)	Male ; Humans ; Female ; Aged ; Functional Food ; Feeding Behavior ; Diet ; Vegetables ; Diet, Mediterranean ; Italy ; Telephone ; Computers
Language	English
Publishing date	2024-03-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16060762
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Article ; Online: Multivariate prediction of Saliva Precipitation Index for relating selected chemical parameters of red wines to the sensory perception of astringency.

Galaz Torres, Cristian / Ricci, Arianna / Parpinello, Giuseppina Paola / Gambuti, Angelita / Rinaldi, Alessandra / Moio, Luigi / Rolle, Luca / Paissoni, Maria Alessandra / Mattivi, Fulvio / Perenzoni, Daniele / Arapitsas, Panagiotis / Marangon, Matteo / Mayr Marangon, Christine / Slaghenaufi, Davide / Ugliano, Maurizio / Versari, Andrea

Current research in food science

2023 Volume 7, Page(s) 100626

Abstract: Astringency is an essential sensory attribute of red wine closely related to the saliva precipitation upon contact with the wine. In this study a data matrix of 52 physico-chemical parameters was used to predict the Saliva Precipitation Index (SPI) in ... ...

Abstract	Astringency is an essential sensory attribute of red wine closely related to the saliva precipitation upon contact with the wine. In this study a data matrix of 52 physico-chemical parameters was used to predict the Saliva Precipitation Index (SPI) in 110 Italian mono-varietal red wines using partial least squares regression (PLSr) with variable selection by Variable Importance for Projection (VIP) and the significance of regression coefficients. The final PLSr model, evaluated using a test data set, had 3 components and yielded an R
Language	English
Publishing date	2023-10-26
Publishing country	Netherlands
Document type	Journal Article
ISSN	2665-9271
ISSN (online)	2665-9271
DOI	10.1016/j.crfs.2023.100626
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Article ; Online: A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation

Franco Lai / Lorenzo Pelagatti / Chiara Pagnini / Alessio Baldini / Daniele Versari / Simone Magazzini

Emergency Care Journal, Vol 16, Iss

2020 Volume 1

Abstract: A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on ... ...

Abstract	A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels.
Keywords	Acute alcohol intoxication ; ST-segment elevation ; coronary vasospasm ; Medicine (General) ; R5-920
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	PAGEPress Publications
Document type	Article ; Online
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Article ; Online: The contribution of varietal thiols in the diverse aroma of Italian monovarietal white wines.

Carlin, Silvia / Piergiovanni, Maurizio / Pittari, Elisabetta / Tiziana Lisanti, Maria / Moio, Luigi / Piombino, Paola / Marangon, Matteo / Curioni, Andrea / Rolle, Luca / Rìo Segade, Susana / Versari, Andrea / Ricci, Arianna / Parpinello, Giuseppina Paola / Luzzini, Giovanni / Ugliano, Maurizio / Perenzoni, Daniele / Vrhovsek, Urska / Mattivi, Fulvio

Food research international (Ottawa, Ont.)

2022 Volume 157, Page(s) 111404

Abstract: Thanks to their low odor detection thresholds, free varietal thiols (VTs) play a key role in the primary aroma of wines, to which they confer an intense scent reminiscent of box tree, grapefruit, citrus fruits, passionfruit and cat urine odor. Excluding ... ...

Abstract	Thanks to their low odor detection thresholds, free varietal thiols (VTs) play a key role in the primary aroma of wines, to which they confer an intense scent reminiscent of box tree, grapefruit, citrus fruits, passionfruit and cat urine odor. Excluding wines from a few VT-rich grapevine cultivars, VTs appear to be present in most cultivars at trace levels, although a comprehensive dataset is still missing. The low concentration of VTs combined with their high reactivity and matrix complexity make their determination in wines a challenging task. In this research an optimized liquid chromatography - tandem mass spectrometry (LC-MS/MS) method was validated and used for the quantification of 4-methyl-4-sulfanylpentan-2-one (4-MSP), 3-sulfanylhexan-1-ol (3-SH), 3-sulfanylhexyl acetate (3-SHA) and ethyl 3-sulfanylpropionate (E3SP) in 246 samples (vintage 2019) representative of 18 monovarietal Italian white wines. VTs were detected in all cultivars even though higher values of 3-SH were found in Lugana, Müller-Thurgau and Verdicchio cultivars. Müller-Thurgau wines showed the highest level of 4-MSP, that was mainly correlated to the odor descriptors of passionfruit and box tree/cat urine. The VTs composition of Müller-Thurgau was confirmed on a second set of 50 wines from different vintages. From a sensory perspective, the samples of Müller-Thurgau showed the best positive correlations between chemical variables and the odor descriptors thiol note, passion fruit and box tree/cat urine. These notes are significantly related to 4-MSP, suggesting that it could play a relevant olfactory role for the aroma of Müller-Thurgau wines. Sorting analysis allowed to group these wines according to their thiolic characteristics. The chemical variables and the odor descriptors attributable to the thiol notes are important for Müller-Thurgau and Lugana wines, while the contribution of thiol notes was sensorially negligible for the other wines.
MeSH term(s)	Chromatography, Liquid ; Italy ; Odorants/analysis ; Sulfhydryl Compounds/chemistry ; Tandem Mass Spectrometry ; Wine/analysis
Chemical Substances	Sulfhydryl Compounds
Language	English
Publishing date	2022-05-25
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1111695-x
ISSN	1873-7145 ; 0963-9969
ISSN (online)	1873-7145
ISSN	0963-9969
DOI	10.1016/j.foodres.2022.111404
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Article: Omega 3 : where do we stand?

Versari, Daniele / Daghini, Elena / Salvetti, Guido / Salvetti, Antonio

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension

2013 Volume 15, Issue 4, Page(s) 225–230

Abstract: Omega-3 fatty acids are essential polyunsaturated fatty acids that are crucial components of plasma membrane phospholipids. They influence cell structure and function and have anti-thrombotic and anti-arrhythmic properties, thus potentially exerting a ... ...

Abstract	Omega-3 fatty acids are essential polyunsaturated fatty acids that are crucial components of plasma membrane phospholipids. They influence cell structure and function and have anti-thrombotic and anti-arrhythmic properties, thus potentially exerting a favourable action on primary and secondary prevention of cardiovascular events. However, the supposed beneficial effect of omega-3 fatty acids in the management of cardiovascular risk has been evaluated only in a relatively small number of interventional studies, with results that are not consistent and are only suggestive of a putative beneficial effect of omega-3 supplementation on the prevention of cardiovascular mortality. Benefits have been reported mainly for the prevention of sudden death in patients with recent myocardial infarction and for primary and secondary prevention of nonfatal cardiac events in populations with high fish intake. Therefore, only ongoing trials will provide definitive data to elucidate whether omega-3 fatty acids could represent a new therapeutic approach for cardiovascular disease.
Language	English
Publishing date	2013-01-22
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	1236337-6
ISSN	1179-1985 ; 1120-9879
ISSN (online)	1179-1985
ISSN	1120-9879
DOI	10.2165/0151642-200815040-00002
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Article ; Online: Decoding the Proanthocyanins Profile of Italian Red Wines

Arapitsas, Panagiotis / Perenzoni, Daniele / Ugliano, Maurizio / Slaghenaufi, Davide / Giacosa, Simone / Paissoni, Maria Alessandra / Piombino, Paola / Pittari, Elisabetta / Versari, Andrea / Ricci, Arianna / Curioni, Andrea / Marangon, Matteo / Mattivi, Fulvio

Beverages. 2022 Nov. 25, v. 8, no. 4

2022

Abstract: The Italian wine appellations system is organized in hundreds of origin wines, with unique characteristics that are protected with many denominations of origin. The aim of this work was to analyze and compare the proanthocyanin profile of 12 single- ... ...

Abstract	The Italian wine appellations system is organized in hundreds of origin wines, with unique characteristics that are protected with many denominations of origin. The aim of this work was to analyze and compare the proanthocyanin profile of 12 single-cultivar and single-vintage Italian red wine groups (Aglianico from Campania, Cannonau from Sardinia, Corvina from Veneto, Montepulciano from Abruzzo, Nebbiolo from Piedmont, Nerello Mascalese from Sicily, Primitivo from Apulia, Raboso Piave from Veneto, Sagrantino from Umbria, Sangiovese from Tuscany and Romagna, and Teroldego from Trentino), each one produced in their terroirs under ad hoc legal frameworks to guarantee their quality and origin. All wines were analyzed with a protocol that combined the phloroglucinolysis reaction with an LC-MS/MS instrument. The results underlined Sagrantino wines as the richest in proanthocyanins. Sangiovese, Montepulciano, Nerello, and Teroldego were the richest in B-ring trihydroxylated flavan-3-ols, and especially Nerello was the richest in prodelphinidins. Cannonau, Raboso Piave, Nerello, and Corvina were characterized by C-ring trans conformation flavan-3-ols. Nebbiolo and Corvina had high percentages of galloylated flavan-3-ols. Aglianico and Primitivo had the lowest percentages of B-ring trihydroxylated and C-ring trans conformation flavan-3-ols. This information should be useful in better understanding the Italian red wines and valorize them.
Keywords	Sciaenidae ; flavanols ; piedmont ; red wines ; Italy ; Sardinia ; Sicily
Language	English
Dates of publication	2022-1125
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2785444-9
ISSN	2306-5710
ISSN	2306-5710
DOI	10.3390/beverages8040076
Database	NAL-Catalogue (AGRICOLA)

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Article: Long life to olive oil and wine! Long life with olive oil and wine?

Versari, Daniele / Ghiadoni, Lorenzo / Taddei, Stefano

Journal of hypertension

2008 Volume 26, Issue 2, Page(s) 186–187

MeSH term(s)	Antioxidants/metabolism ; Blood Pressure/physiology ; Cross-Over Studies ; Diet, Mediterranean ; Humans ; Hypertension/diet therapy ; Life Expectancy ; Olive Oil ; Plant Oils/metabolism ; Wine
Chemical Substances	Antioxidants ; Olive Oil ; Plant Oils
Language	English
Publishing date	2008-02
Publishing country	England
Document type	Comment ; Editorial
ZDB-ID	605532-1
ISSN	1473-5598 ; 0263-6352 ; 0952-1178
ISSN (online)	1473-5598
ISSN	0263-6352 ; 0952-1178
DOI	10.1097/HJH.0b013e3282f4a631
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Article ; Online: The contribution of varietal thiols in the diverse aroma of Italian monovarietal white wines

Carlin, Silvia / Piergiovanni, Maurizio / Pittari, Elisabetta / Tiziana Lisanti, Maria / Moio, Luigi / Piombino, Paola / Marangon, Matteo / Curioni, Andrea / Rolle, Luca / Río Segade, Susana / Versari, Andrea / Ricci, Arianna / Parpinello, Giuseppina Paola / Luzzini, Giovanni / Ugliano, Maurizio / Perenzoni, Daniele / Vrhovsek, Urska / Mattivi, Fulvio

Food Research International. 2022 July, v. 157 p.111404-

2022

Abstract	Thanks to their low odor detection thresholds, free varietal thiols (VTs) play a key role in the primary aroma of wines, to which they confer an intense scent reminiscent of box tree, grapefruit, citrus fruits, passionfruit and cat urine odor. Excluding wines from a few VT-rich grapevine cultivars, VTs appear to be present in most cultivars at trace levels, although a comprehensive dataset is still missing. The low concentration of VTs combined with their high reactivity and matrix complexity make their determination in wines a challenging task. In this research an optimized liquid chromatography – tandem mass spectrometry (LC-MS/MS) method was validated and used for the quantification of 4-methyl-4-sulfanylpentan-2-one (4-MSP), 3-sulfanylhexan-1-ol (3-SH), 3-sulfanylhexyl acetate (3-SHA) and ethyl 3-sulfanylpropionate (E3SP) in 246 samples (vintage 2019) representative of 18 monovarietal Italian white wines. VTs were detected in all cultivars even though higher values of 3-SH were found in Lugana, Müller-Thurgau and Verdicchio cultivars. Müller-Thurgau wines showed the highest level of 4-MSP, that was mainly correlated to the odor descriptors of passionfruit and box tree/cat urine. The VTs composition of Müller-Thurgau was confirmed on a second set of 50 wines from different vintages. From a sensory perspective, the samples of Müller-Thurgau showed the best positive correlations between chemical variables and the odor descriptors thiol note, passion fruit and box tree/cat urine. These notes are significantly related to 4-MSP, suggesting that it could play a relevant olfactory role for the aroma of Müller-Thurgau wines. Sorting analysis allowed to group these wines according to their thiolic characteristics. The chemical variables and the odor descriptors attributable to the thiol notes are important for Müller-Thurgau and Lugana wines, while the contribution of thiol notes was sensorially negligible for the other wines.
Keywords	Citrus ; Vitis ; acetates ; cultivars ; data collection ; food research ; grapefruits ; liquid chromatography ; odors ; passion fruits ; tandem mass spectrometry ; thiols ; trees ; urine ; Volatile thiols ; White wine ; LC-MS/MS ; Sensory analysis ; Müller-Thurgau ; Verdicchio ; Lugana ; Ebselen ; 4-Methyl-4-sulfanylpentan-2-one ; 3-Sulfanylhexan-1-ol ; 3-Sulfanylhexyl acetate ; Ethyl 3-sulfanylpropionate
Language	English
Dates of publication	2022-07
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	1111695-x
ISSN	1873-7145 ; 0963-9969
ISSN (online)	1873-7145
ISSN	0963-9969
DOI	10.1016/j.foodres.2022.111404
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Phosphodiesterase 5 inhibition in essential hypertension.

Ghiadoni, Lorenzo / Versari, Daniele / Taddei, Stefano

Current hypertension reports

2008 Volume 10, Issue 1, Page(s) 52–57

Abstract: Phosphodiesterase (PDE) 5 inhibitors reduce cyclic guanylate monophosphate breakdown, promoting vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. Sildenafil, vardenafil, and tadalafil were approved as effective ... ...

Abstract	Phosphodiesterase (PDE) 5 inhibitors reduce cyclic guanylate monophosphate breakdown, promoting vascular relaxation in the corpora cavernosa and penile erection during sexual stimulation. Sildenafil, vardenafil, and tadalafil were approved as effective treatments for male erectile dysfunction. Because PDE5 is present in artery and vein smooth muscle cells throughout the body, PDE5 inhibitors have mild systemic vasodilatory effects and thus the potential to impact the vascular system. The US Food and Drug Administration has approved PDE5 inhibitors for treating pulmonary hypertension. Moreover, their systemic vasodilating properties theoretically make these drugs suitable for treating hypertension. Studies indicate that PDE5 inhibition may be an option for reducing blood pressure in hypertensive patients. Additional benefits may be related to improved arterial stiffness and endothelial dysfunction, two early vascular abnormalities characterizing essential hypertension. More investigation is needed on PDE5 inhibitors as antihypertensive drugs, especially with slow-release formulations or compounds with long half-life. Studies on safety during long-term administration, interactions with antihypertensive and nonantihypertensive drugs, and effect on target organ damage are needed.
MeSH term(s)	Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Carbolines/therapeutic use ; Endothelium/drug effects ; Humans ; Hypertension/drug therapy ; Imidazoles/therapeutic use ; Phosphodiesterase 5 Inhibitors ; Phosphodiesterase Inhibitors/therapeutic use ; Piperazines/therapeutic use ; Purines/therapeutic use ; Sildenafil Citrate ; Sulfones/therapeutic use ; Tadalafil ; Triazines/therapeutic use ; Vardenafil Dihydrochloride
Chemical Substances	Antihypertensive Agents ; Carbolines ; Imidazoles ; Phosphodiesterase 5 Inhibitors ; Phosphodiesterase Inhibitors ; Piperazines ; Purines ; Sulfones ; Triazines ; Vardenafil Dihydrochloride (5O8R96XMH7) ; Tadalafil (742SXX0ICT) ; Sildenafil Citrate (BW9B0ZE037)
Language	English
Publishing date	2008-03-26
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2057367-4
ISSN	1534-3111 ; 1522-6417
ISSN (online)	1534-3111
ISSN	1522-6417
DOI	10.1007/s11906-008-0011-4
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Article: Control of blood pressure in the community: an unsolved problem.

Salvetti, Antonio / Versari, Daniele

Current pharmaceutical design

2003 Volume 9, Issue 29, Page(s) 2375–2384

Abstract: Available data indicate that blood pressure (BP) is reduced below 140-90 mmHg in less than 30% of hypertensive patients. This poor control of BP derives from lack of diagnosis (unawareness of hypertension), lack of treatment of aware hypertensive ... ...

Abstract	Available data indicate that blood pressure (BP) is reduced below 140-90 mmHg in less than 30% of hypertensive patients. This poor control of BP derives from lack of diagnosis (unawareness of hypertension), lack of treatment of aware hypertensive patients and lack of efficacy of treatment. Systolic BP (SBP) is now considered as the most important parameter for diagnosis and stadiation of hypertension, above all in elderly patients, and the most frequent cause of unsatisfactory control of BP in the population. Lack of SBP control is caused both by physicians' attitude and difficulty in reducing SBP. Physicians are more prone to consider diastolic BP as the most important parameter for diagnosis and stadiation of hypertension, decision to treat and intensification of treatment and therefore SBP is often forgotten and-or misinterpreted in this decision making process. On the other hand, since current antihypertensive drugs are equally effective in lowering SBP and DBP and-or less effective in lowering SBP more than DBP, SBP is often uncontrolled in treated patients with isolated systolic hypertension or prevalent increase in SBP. The possibility of obtaining better control of SBP in the future is linked to better education of physicians, who need to pay greater attention to SBP as a parameter for diagnosing, treating and intensifying treatment, and to the development of new drugs more active in reducing SBP.
MeSH term(s)	Age of Onset ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Epidemiologic Studies ; Gender Identity ; Health Status ; Health Surveys ; Humans ; Hypertension/epidemiology ; Hypertension/physiopathology ; Hypertension/prevention & control ; Population Dynamics ; Prognosis ; Risk Factors ; Socioeconomic Factors ; Systole/drug effects ; Systole/physiology
Language	English
Publishing date	2003
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	1304236-1
ISSN	1873-4286 ; 1381-6128
ISSN (online)	1873-4286
ISSN	1381-6128
DOI	10.2174/1381612033453848
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